Published in J Biol Chem on June 12, 2007
The yeast lysosome-like vacuole: endpoint and crossroads. Biochim Biophys Acta (2008) 2.22
Function, structure and regulation of the vacuolar (H+)-ATPases. Arch Biochem Biophys (2008) 1.68
Regulation and isoform function of the V-ATPases. Biochemistry (2010) 1.57
The Ras/cAMP/protein kinase A pathway regulates glucose-dependent assembly of the vacuolar (H+)-ATPase in yeast. J Biol Chem (2008) 1.33
Structure and regulation of the vacuolar ATPases. Biochim Biophys Acta (2008) 1.29
Consequences of loss of Vph1 protein-containing vacuolar ATPases (V-ATPases) for overall cellular pH homeostasis. J Biol Chem (2011) 1.01
Function and subunit interactions of the N-terminal domain of subunit a (Vph1p) of the yeast V-ATPase. J Biol Chem (2008) 0.97
Targeting reversible disassembly as a mechanism of controlling V-ATPase activity. Curr Protein Pept Sci (2012) 0.96
Aldolase directly interacts with ARNO and modulates cell morphology and acidic vesicle distribution. Am J Physiol Cell Physiol (2011) 0.91
Sorting of the yeast vacuolar-type, proton-translocating ATPase enzyme complex (V-ATPase): identification of a necessary and sufficient Golgi/endosomal retention signal in Stv1p. J Biol Chem (2012) 0.88
The vacuolar (H+)-ATPase: subunit arrangement and in vivo regulation. J Bioenerg Biomembr (2007) 0.87
The RAVE complex is an isoform-specific V-ATPase assembly factor in yeast. Mol Biol Cell (2013) 0.85
Organelle-specific isoenzymes of plant V-ATPase as revealed by in vivo-FRET analysis. BMC Cell Biol (2008) 0.84
The reconstructed ancestral subunit a functions as both V-ATPase isoforms Vph1p and Stv1p in Saccharomyces cerevisiae. Mol Biol Cell (2011) 0.84
Disorders of lysosomal acidification-The emerging role of v-ATPase in aging and neurodegenerative disease. Ageing Res Rev (2016) 0.80
The V-ATPase in Paramecium: functional specialization by multiple gene isoforms. Pflugers Arch (2008) 0.80
pH-dependent localization of Btn1p in the yeast model for Batten disease. Dis Model Mech (2010) 0.80
The vacuolar ATPase from Entamoeba histolytica: molecular cloning of the gene encoding for the B subunit and subcellular localization of the protein. BMC Microbiol (2008) 0.79
Organelle acidification negatively regulates vacuole membrane fusion in vivo. Sci Rep (2016) 0.75
Direct interaction of the Golgi V-ATPase a-subunit isoform with PI(4)P drives localization of Golgi V-ATPases in yeast. Mol Biol Cell (2017) 0.75
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res (1992) 34.33
Getting started with yeast. Methods Enzymol (2002) 6.60
The vacuolar (H+)-ATPases--nature's most versatile proton pumps. Nat Rev Mol Cell Biol (2002) 5.19
VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae. J Cell Biol (1995) 5.04
ATP synthase--a marvellous rotary engine of the cell. Nat Rev Mol Cell Biol (2001) 4.81
Trans-complex formation by proteolipid channels in the terminal phase of membrane fusion. Nature (2001) 4.10
Activation of lysosomal function during dendritic cell maturation. Science (2003) 3.22
Defects in TCIRG1 subunit of the vacuolar proton pump are responsible for a subset of human autosomal recessive osteopetrosis. Nat Genet (2000) 3.12
The v-ATPase V0 subunit a1 is required for a late step in synaptic vesicle exocytosis in Drosophila. Cell (2005) 3.05
The where, when, and how of organelle acidification by the yeast vacuolar H+-ATPase. Microbiol Mol Biol Rev (2006) 2.79
Renal vacuolar H+-ATPase. Physiol Rev (2004) 2.47
Mutations in ATP6N1B, encoding a new kidney vacuolar proton pump 116-kD subunit, cause recessive distal renal tubular acidosis with preserved hearing. Nat Genet (2000) 2.38
Protein transport from the late Golgi to the vacuole in the yeast Saccharomyces cerevisiae. Biochim Biophys Acta (2005) 2.36
Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathway. J Cell Biol (2004) 2.31
Disassembly and reassembly of the yeast vacuolar H(+)-ATPase in vivo. J Biol Chem (1995) 2.27
The membrane protein alkaline phosphatase is delivered to the vacuole by a route that is distinct from the VPS-dependent pathway. J Cell Biol (1997) 2.24
The VPH1 gene encodes a 95-kDa integral membrane polypeptide required for in vivo assembly and activity of the yeast vacuolar H(+)-ATPase. J Biol Chem (1992) 2.07
Vacuolar H+-ATPase in human breast cancer cells with distinct metastatic potential: distribution and functional activity. Am J Physiol Cell Physiol (2004) 2.01
The V0-ATPase mediates apical secretion of exosomes containing Hedgehog-related proteins in Caenorhabditis elegans. J Cell Biol (2006) 1.99
From lysosomes to the plasma membrane: localization of vacuolar-type H+ -ATPase with the a3 isoform during osteoclast differentiation. J Biol Chem (2003) 1.91
Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly. Nat Cell Biol (2001) 1.89
STV1 gene encodes functional homologue of 95-kDa yeast vacuolar H(+)-ATPase subunit Vph1p. J Biol Chem (1994) 1.87
Evidence for rotation of V1-ATPase. Proc Natl Acad Sci U S A (2003) 1.84
Regulation of plasma membrane V-ATPase activity by dissociation of peripheral subunits. J Biol Chem (1995) 1.77
The class C Vps complex functions at multiple stages of the vacuolar transport pathway. Traffic (2001) 1.73
Reversible association between the V1 and V0 domains of yeast vacuolar H+-ATPase is an unconventional glucose-induced effect. Mol Cell Biol (1998) 1.71
Vacuole membrane fusion: V0 functions after trans-SNARE pairing and is coupled to the Ca2+-releasing channel. J Cell Biol (2003) 1.68
Crystal structure of a central stalk subunit C and reversible association/dissociation of vacuole-type ATPase. Proc Natl Acad Sci U S A (2003) 1.66
Phosphatidylinositol 3-kinase-mediated effects of glucose on vacuolar H+-ATPase assembly, translocation, and acidification of intracellular compartments in renal epithelial cells. Mol Cell Biol (2005) 1.62
Distinct expression patterns of different subunit isoforms of the V-ATPase in the rat epididymis. Biol Reprod (2005) 1.53
The amino-terminal domain of the vacuolar proton-translocating ATPase a subunit controls targeting and in vivo dissociation, and the carboxyl-terminal domain affects coupling of proton transport and ATP hydrolysis. J Biol Chem (2001) 1.52
Subunit rotation of vacuolar-type proton pumping ATPase: relative rotation of the G and C subunits. J Biol Chem (2003) 1.50
Yeast V-ATPase complexes containing different isoforms of the 100-kDa a-subunit differ in coupling efficiency and in vivo dissociation. J Biol Chem (2001) 1.47
The H subunit (Vma13p) of the yeast V-ATPase inhibits the ATPase activity of cytosolic V1 complexes. J Biol Chem (2000) 1.47
The RAVE complex is essential for stable assembly of the yeast V-ATPase. J Biol Chem (2002) 1.44
VPS21 controls entry of endocytosed and biosynthetic proteins into the yeast prevacuolar compartment. Mol Biol Cell (2000) 1.40
Arg-735 of the 100-kDa subunit a of the yeast V-ATPase is essential for proton translocation. Proc Natl Acad Sci U S A (2001) 1.35
A journey from mammals to yeast with vacuolar H+-ATPase (V-ATPase). J Bioenerg Biomembr (2003) 1.28
Studying yeast vacuoles. Methods Enzymol (2002) 1.22
Cysteine 254 of the 73-kDa A subunit is responsible for inhibition of the coated vesicle (H+)-ATPase upon modification by sulfhydryl reagents. J Biol Chem (1992) 1.22
Cysteine-mediated cross-linking indicates that subunit C of the V-ATPase is in close proximity to subunits E and G of the V1 domain and subunit a of the V0 domain. J Biol Chem (2005) 1.19
Characterization of the V0 domain of the coated vesicle (H+)-ATPase. J Biol Chem (1992) 1.15
Activation of proton pumping in human neutrophils occurs by exocytosis of vesicles bearing vacuolar-type H+-ATPases. J Biol Chem (1996) 1.08
Molecular cloning and expression of three isoforms of the 100-kDa a subunit of the mouse vacuolar proton-translocating ATPase. J Biol Chem (2000) 1.08
a4, a unique kidney-specific isoform of mouse vacuolar H+-ATPase subunit a. J Biol Chem (2001) 1.07
Involvement of the nonhomologous region of subunit A of the yeast V-ATPase in coupling and in vivo dissociation. J Biol Chem (2004) 1.04
Gene disruption. Methods Enzymol (2002) 1.03
Microtubules are involved in glucose-dependent dissociation of the yeast vacuolar [H+]-ATPase in vivo. J Biol Chem (2001) 0.98
Interacting helical surfaces of the transmembrane segments of subunits a and c' of the yeast V-ATPase defined by disulfide-mediated cross-linking. J Biol Chem (2003) 0.94
The vacuolar (H+)-ATPases--nature's most versatile proton pumps. Nat Rev Mol Cell Biol (2002) 5.19
Function, structure and regulation of the vacuolar (H+)-ATPases. Arch Biochem Biophys (2008) 1.68
Regulation and isoform function of the V-ATPases. Biochemistry (2010) 1.57
Function of a subunit isoforms of the V-ATPase in pH homeostasis and in vitro invasion of MDA-MB231 human breast cancer cells. J Biol Chem (2009) 1.57
V-ATPase functions in normal and disease processes. Pflugers Arch (2007) 1.44
The Ras/cAMP/protein kinase A pathway regulates glucose-dependent assembly of the vacuolar (H+)-ATPase in yeast. J Biol Chem (2008) 1.33
Structure and regulation of the vacuolar ATPases. Biochim Biophys Acta (2008) 1.29
Cysteine-mediated cross-linking indicates that subunit C of the V-ATPase is in close proximity to subunits E and G of the V1 domain and subunit a of the V0 domain. J Biol Chem (2005) 1.19
Subunit H of the vacuolar (H+) ATPase inhibits ATP hydrolysis by the free V1 domain by interaction with the rotary subunit F. J Biol Chem (2007) 1.15
Three-dimensional structure of the vacuolar ATPase. Localization of subunit H by difference imaging and chemical cross-linking. J Biol Chem (2004) 1.14
Cysteine-directed cross-linking to subunit B suggests that subunit E forms part of the peripheral stalk of the vacuolar H+-ATPase. J Biol Chem (2001) 1.10
Subunit a of the yeast V-ATPase participates in binding of bafilomycin. J Biol Chem (2005) 1.09
Localization of subunits D, E, and G in the yeast V-ATPase complex using cysteine-mediated cross-linking to subunit B. Biochemistry (2002) 1.08
Involvement of the nonhomologous region of subunit A of the yeast V-ATPase in coupling and in vivo dissociation. J Biol Chem (2004) 1.04
Definition of membrane topology and identification of residues important for transport in subunit a of the vacuolar ATPase. J Biol Chem (2011) 1.03
Arrangement of subunits in the proteolipid ring of the V-ATPase. J Biol Chem (2007) 1.02
Heme-binding protein HRG-1 is induced by insulin-like growth factor I and associates with the vacuolar H+-ATPase to control endosomal pH and receptor trafficking. J Biol Chem (2009) 0.97
Function and subunit interactions of the N-terminal domain of subunit a (Vph1p) of the yeast V-ATPase. J Biol Chem (2008) 0.97
Mutational analysis of the non-homologous region of subunit A of the yeast V-ATPase. J Biol Chem (2003) 0.96
Analysis of the membrane topology of transmembrane segments in the C-terminal hydrophobic domain of the yeast vacuolar ATPase subunit a (Vph1p) by chemical modification. J Biol Chem (2008) 0.96
Proton translocation driven by ATP hydrolysis in V-ATPases. FEBS Lett (2003) 0.96
Structure and regulation of the V-ATPases. J Bioenerg Biomembr (2005) 0.95
Expression and function of the mouse V-ATPase d subunit isoforms. J Biol Chem (2003) 0.95
Interacting helical surfaces of the transmembrane segments of subunits a and c' of the yeast V-ATPase defined by disulfide-mediated cross-linking. J Biol Chem (2003) 0.94
Structure, subunit function and regulation of the coated vesicle and yeast vacuolar (H(+))-ATPases. Biochim Biophys Acta (2002) 0.91
The first putative transmembrane segment of subunit c" (Vma16p) of the yeast V-ATPase is not necessary for function. J Biol Chem (2002) 0.90
Localization of subunit C (Vma5p) in the yeast vacuolar ATPase by immuno electron microscopy. FEBS Lett (2006) 0.89
TM2 but not TM4 of subunit c'' interacts with TM7 of subunit a of the yeast V-ATPase as defined by disulfide-mediated cross-linking. J Biol Chem (2004) 0.88
The vacuolar (H+)-ATPase: subunit arrangement and in vivo regulation. J Bioenerg Biomembr (2007) 0.87
Regulated assembly of vacuolar ATPase is increased during cluster disruption-induced maturation of dendritic cells through a phosphatidylinositol 3-kinase/mTOR-dependent pathway. J Biol Chem (2013) 0.87
Subunit structure, function, and arrangement in the yeast and coated vesicle V-ATPases. J Bioenerg Biomembr (2003) 0.85
The function of vacuolar ATPase (V-ATPase) a subunit isoforms in invasiveness of MCF10a and MCF10CA1a human breast cancer cells. J Biol Chem (2013) 0.85
Synthesis of photoactivatable acyclic analogues of the lobatamides. J Org Chem (2005) 0.82
Tissue specific expression of the splice variants of the mouse vacuolar proton-translocating ATPase a4 subunit. Biochem Biophys Res Commun (2007) 0.80
Structural analysis of the N-terminal domain of subunit a of the yeast vacuolar ATPase (V-ATPase) using accessibility of single cysteine substitutions to chemical modification. J Biol Chem (2013) 0.79