Published in J Immunol on March 15, 2003
A recent perspective on alcohol, immunity, and host defense. Alcohol Clin Exp Res (2008) 2.50
Mechanisms of neutrophil accumulation in the lungs against bacteria. Am J Respir Cell Mol Biol (2009) 1.28
Focus on: Alcohol and the immune system. Alcohol Res Health (2010) 1.11
Alcohol stimulates activation of Snail, epidermal growth factor receptor signaling, and biomarkers of epithelial-mesenchymal transition in colon and breast cancer cells. Alcohol Clin Exp Res (2009) 1.09
Alcohol-use disorders in the critically ill patient. Chest (2010) 1.07
Alcoholism: a systemic proinflammatory condition. World J Gastroenterol (2014) 0.96
Ethanol causes the redistribution of L1 cell adhesion molecule in lipid rafts. J Neurochem (2011) 0.92
Inhibition of TLR8- and TLR4-induced Type I IFN induction by alcohol is different from its effects on inflammatory cytokine production in monocytes. BMC Immunol (2011) 0.90
Tumour necrosis factor receptor 1 and mortality in a multi-ethnic cohort: the Northern Manhattan Study. Age Ageing (2013) 0.89
Ethanol upregulates glucocorticoid-induced leucine zipper expression and modulates cellular inflammatory responses in lung epithelial cells. J Immunol (2010) 0.87
Alcohol abuse and Streptococcus pneumoniae infections: consideration of virulence factors and impaired immune responses. Alcohol (2011) 0.87
Alcohol exposure impairs myeloid dendritic cell function in rhesus macaques. Alcohol Clin Exp Res (2009) 0.86
Alcohol reversibly disrupts TNF-alpha/TACE interactions in the cell membrane. Respir Res (2005) 0.86
Mmp23b promotes liver development and hepatocyte proliferation through the tumor necrosis factor pathway in zebrafish. Hepatology (2010) 0.83
Alcohol exposure alters mouse lung inflammation in response to inhaled dust. Nutrients (2012) 0.82
Investigation of the role of TNF-α converting enzyme (TACE) in the inhibition of cell surface and soluble TNF-α production by acute ethanol exposure. PLoS One (2012) 0.80
The size of the unbranched aliphatic chain determines the immunomodulatory potency of short and long chain n-alkanols. J Biol Chem (2013) 0.80
Binge alcohol exposure modulates rodent expression of biomarkers of the immunoinflammatory response to orthopaedic trauma. J Bone Joint Surg Am (2011) 0.79
Potential Role of the Gut/Liver/Lung Axis in Alcohol-Induced Tissue Pathology. Biomolecules (2015) 0.78
Alveolar macrophage inflammatory mediator expression is elevated in the setting of alcohol use disorders. Alcohol (2015) 0.77
Alcohol abuse and smoking alter inflammatory mediator production by pulmonary and systemic immune cells. Am J Physiol Lung Cell Mol Physiol (2016) 0.76
Association between circulating inflammatory molecules and alcoholic liver disease in men. Cell Stress Chaperones (2016) 0.75
Chronic alcohol exposure, infection, extended circulating white blood cells differentiated by flow cytometry and neutrophil CD64 expression: a prospective, descriptive study of critically ill medical patients. Ann Intensive Care (2012) 0.75
The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity (2008) 10.55
IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nat Med (2008) 9.05
Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice. Nat Immunol (2007) 6.67
Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae. J Exp Med (2005) 6.37
A protective function for interleukin 17A in T cell-mediated intestinal inflammation. Nat Immunol (2009) 5.26
Targeting IL-17 and TH17 cells in chronic inflammation. Nat Rev Drug Discov (2012) 4.70
Simian immunodeficiency virus-induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut. Nat Med (2008) 4.68
Cutting edge: roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection. J Immunol (2003) 4.45
Interleukin-17A mediates acquired immunity to pneumococcal colonization. PLoS Pathog (2008) 4.05
Control of TH17 cells occurs in the small intestine. Nature (2011) 4.03
TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice. J Immunol (2008) 3.42
IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice. J Clin Invest (2010) 3.40
Interleukin-17 is required for T helper 1 cell immunity and host resistance to the intracellular pathogen Francisella tularensis. Immunity (2009) 3.33
Th17 cells and mucosal host defense. Semin Immunol (2007) 3.17
The beta-glucan receptor dectin-1 recognizes specific morphologies of Aspergillus fumigatus. PLoS Pathog (2005) 3.13
The development of inducible bronchus-associated lymphoid tissue depends on IL-17. Nat Immunol (2011) 3.13
Critical role of IL-17 receptor signaling in acute TNBS-induced colitis. Inflamm Bowel Dis (2006) 3.09
IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. J Immunol (2005) 3.02
Proinflammatory T helper type 17 cells are effective B-cell helpers. Proc Natl Acad Sci U S A (2010) 2.88
Allergic sensitization through the airway primes Th17-dependent neutrophilia and airway hyperresponsiveness. Am J Respir Crit Care Med (2009) 2.72
Blockade of interleukin-17A results in reduced atherosclerosis in apolipoprotein E-deficient mice. Circulation (2010) 2.69
Interleukin-17/interleukin-17 receptor-mediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infection. Infect Immun (2005) 2.66
Alveolar macrophage-mediated killing of Pneumocystis carinii f. sp. muris involves molecular recognition by the Dectin-1 beta-glucan receptor. J Exp Med (2003) 2.52
Critical role of IL-17RA in immunopathology of influenza infection. J Immunol (2009) 2.51
The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone. J Cell Biol (2004) 2.41
Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: role of signal transducer and activator of transcription 3. Hepatology (2010) 2.40
TH17 cells in asthma and COPD. Annu Rev Physiol (2010) 2.36
Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F. J Immunol (2007) 2.24
Cxcr2 and Cxcl5 regulate the IL-17/G-CSF axis and neutrophil homeostasis in mice. J Clin Invest (2012) 2.18
Th17 cells mediate clade-specific, serotype-independent mucosal immunity. Immunity (2011) 2.15
Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: potential therapy for cystic fibrosis. Proc Natl Acad Sci U S A (2004) 2.09
Alcohol, immunosuppression, and the lung. Proc Am Thorac Soc (2005) 2.08
IL-23 mediates inflammatory responses to mucoid Pseudomonas aeruginosa lung infection in mice. Am J Physiol Lung Cell Mol Physiol (2006) 2.06
Alcohol, host defence and society. Nat Rev Immunol (2002) 2.05
Multicenter, double-blind, placebo-controlled study of the use of filgrastim in patients hospitalized with pneumonia and severe sepsis. Crit Care Med (2003) 1.98
Stem cells and cell therapies in lung biology and lung diseases. Proc Am Thorac Soc (2008) 1.98
The ERBB4/HER4 intracellular domain 4ICD is a BH3-only protein promoting apoptosis of breast cancer cells. Cancer Res (2006) 1.94
Lipocalin 2 is required for pulmonary host defense against Klebsiella infection. J Immunol (2009) 1.93
Interleukin-17 receptor deficiency results in impaired synovial expression of interleukin-1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destruction during chronic reactivated streptococcal cell wall-induced arthritis. Arthritis Rheum (2005) 1.93
The NOD2 defect in Blau syndrome does not result in excess interleukin-1 activity. Arthritis Rheum (2009) 1.87
Selective transport of cytokine-induced neutrophil chemoattractant from the lung to the blood facilitates pulmonary neutrophil recruitment. Am J Physiol Lung Cell Mol Physiol (2003) 1.86
The Th17 pathway and inflammatory diseases of the intestines, lungs, and skin. Annu Rev Pathol (2012) 1.80
Th17 cytokines and mucosal immunity. Immunol Rev (2008) 1.80
IL-17 promotes bone erosion in murine collagen-induced arthritis through loss of the receptor activator of NF-kappa B ligand/osteoprotegerin balance. J Immunol (2003) 1.78
IL-17-mediated monocyte migration occurs partially through CC chemokine ligand 2/monocyte chemoattractant protein-1 induction. J Immunol (2010) 1.73
TRIF and IRF-3 binding to the TNF promoter results in macrophage TNF dysregulation and steatosis induced by chronic ethanol. J Immunol (2008) 1.70
IL-17RC is required for immune signaling via an extended SEF/IL-17R signaling domain in the cytoplasmic tail. J Immunol (2010) 1.69
Altered expression of immune modulator and structural genes in neonatal unilateral ureteral obstruction. Kidney Int (2003) 1.67
Coregulation of estrogen receptor by ERBB4/HER4 establishes a growth-promoting autocrine signal in breast tumor cells. Cancer Res (2006) 1.67
Pulmonary interleukin-23 gene delivery increases local T-cell immunity and controls growth of Mycobacterium tuberculosis in the lungs. Infect Immun (2005) 1.65
Cystic fibrosis transmembrane conductance regulator recruitment to phagosomes in neutrophils. J Innate Immun (2013) 1.63
Mechanical ventilators in US acute care hospitals. Disaster Med Public Health Prep (2010) 1.61
IL-17RA is required for CCL2 expression, macrophage recruitment, and emphysema in response to cigarette smoke. PLoS One (2011) 1.61
Interleukin-17 acts independently of TNF-alpha under arthritic conditions. J Immunol (2006) 1.59
Presenilin-dependent gamma-secretase processing regulates multiple ERBB4/HER4 activities. J Biol Chem (2005) 1.57
A functional IL-13 receptor is expressed on polarized murine CD4+ Th17 cells and IL-13 signaling attenuates Th17 cytokine production. J Immunol (2009) 1.57
IL-17 contributes to angiogenesis in rheumatoid arthritis. J Immunol (2010) 1.57
Central role of toll-like receptor 4 signaling and host defense in experimental pneumonia caused by Gram-negative bacteria. Infect Immun (2005) 1.53
Respiratory syncytial virus infection in the absence of STAT 1 results in airway dysfunction, airway mucus, and augmented IL-17 levels. J Allergy Clin Immunol (2005) 1.52
The lineage-c-Kit+Sca-1+ cell response to Escherichia coli bacteremia in Balb/c mice. Stem Cells (2008) 1.49
Suppression of the stem cell antigen-1 response and granulocyte lineage expansion by alcohol during septicemia. Crit Care Med (2011) 1.46
Superusers in social networks for smoking cessation: analysis of demographic characteristics and posting behavior from the Canadian Cancer Society's smokers' helpline online and StopSmokingCenter.net. J Med Internet Res (2012) 1.45
Requirement of IL-17 receptor signaling in radiation-resistant cells in the joint for full progression of destructive synovitis. J Immunol (2005) 1.45
The effect of chronic binge ethanol consumption on the primary stage of SIV infection in rhesus macaques. Alcohol Clin Exp Res (2003) 1.41
Toll/IL-1R domain-containing adaptor protein (TIRAP) is a critical mediator of antibacterial defense in the lung against Klebsiella pneumoniae but not Pseudomonas aeruginosa. J Immunol (2006) 1.40
IL-23 is required for long-term control of Mycobacterium tuberculosis and B cell follicle formation in the infected lung. J Immunol (2011) 1.40
IL-23 is required for protection against systemic infection with Listeria monocytogenes. J Immunol (2009) 1.40
Chronic binge ethanol consumption accelerates progression of simian immunodeficiency virus disease. Alcohol Clin Exp Res (2006) 1.40
Integrating HIV/AIDS and alcohol research. Alcohol Res Health (2010) 1.36
Pharmacologic advances in the treatment and prevention of respiratory syncytial virus. Clin Infect Dis (2010) 1.36
Mechanisms controlling Th17 cytokine expression and host defense. J Leukoc Biol (2011) 1.33
CD4+ T cell-independent DNA vaccination against opportunistic infections. J Clin Invest (2005) 1.33
Regulatory T cells dampen pulmonary inflammation and lung injury in an animal model of pneumocystis pneumonia. J Immunol (2006) 1.31
Stimulation of immature lung macrophages with intranasal interferon gamma in a novel neonatal mouse model of respiratory syncytial virus infection. PLoS One (2012) 1.30
CD1d degradation in Chlamydia trachomatis-infected epithelial cells is the result of both cellular and chlamydial proteasomal activity. J Biol Chem (2007) 1.30
CXCL1 regulates pulmonary host defense to Klebsiella Infection via CXCL2, CXCL5, NF-kappaB, and MAPKs. J Immunol (2010) 1.30
Increased host resistance against Pneumocystis carinii pneumonia in gammadelta T-cell-deficient mice: protective role of gamma interferon and CD8(+) T cells. Infect Immun (2002) 1.30
Conserved natural IgM antibodies mediate innate and adaptive immunity against the opportunistic fungus Pneumocystis murina. J Exp Med (2010) 1.29
Gene therapy-mediated delivery of targeted cytotoxins for glioma therapeutics. Proc Natl Acad Sci U S A (2010) 1.29
Transcriptome analysis of Pseudomonas aeruginosa after interaction with human airway epithelial cells. Infect Immun (2004) 1.29
Directing traffic: IL-17 and IL-22 coordinate pulmonary immune defense. Immunol Rev (2014) 1.28
Alcohol-induced suppression of lung chemokine production and the host defense response to Streptococcus pneumoniae. Alcohol Clin Exp Res (2003) 1.27
AMPK agonists ameliorate sodium and fluid transport and inflammation in cystic fibrosis airway epithelial cells. Am J Respir Cell Mol Biol (2009) 1.27
Vitamin D3 attenuates Th2 responses to Aspergillus fumigatus mounted by CD4+ T cells from cystic fibrosis patients with allergic bronchopulmonary aspergillosis. J Clin Invest (2010) 1.27
Impact of family history of high myopia on level and onset of myopia. Invest Ophthalmol Vis Sci (2004) 1.26
IL-22 is essential for lung epithelial repair following influenza infection. Am J Pathol (2013) 1.26
Identification and characterization of murine SCARA5, a novel class A scavenger receptor that is expressed by populations of epithelial cells. J Biol Chem (2006) 1.25
Requirement of IL-17RA in Con A induced hepatitis and negative regulation of IL-17 production in mouse T cells. J Immunol (2008) 1.25
Role of IL-17A on resolution of pulmonary C. neoformans infection. PLoS One (2011) 1.25