Published in J Ocul Pharmacol Ther on February 01, 2003
Comparative toxicity of preservatives on immortalized corneal and conjunctival epithelial cells. J Ocul Pharmacol Ther (2009) 1.63
New anti-infective coatings of medical implants. Antimicrob Agents Chemother (2008) 0.87
Role of AMP-18 in oral mucositis. Oral Oncol (2011) 0.83
NC-1059: a channel-forming peptide that modulates drug delivery across in vitro corneal epithelium. Invest Ophthalmol Vis Sci (2009) 0.79
Human corneal cell culture models for drug toxicity studies. Drug Deliv Transl Res (2016) 0.75
Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans. Mech Ageing Dev (2006) 5.61
Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians. PLoS One (2010) 3.64
Inflamm-ageing and lifelong antigenic load as major determinants of ageing rate and longevity. FEBS Lett (2005) 2.30
Inflammation markers predicting frailty and mortality in the elderly. Exp Mol Pathol (2006) 1.79
Massive load of functional effector CD4+ and CD8+ T cells against cytomegalovirus in very old subjects. J Immunol (2007) 1.73
LASIK flap creation with the Ziemer femtosecond laser in 787 consecutive eyes. J Refract Surg (2010) 1.53
Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians. Mech Ageing Dev (2005) 1.49
Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010. Arch Toxicol (2011) 1.46
Determination of retinal blood vessel diameters and arteriovenous ratios in systemic hypertension: comparison of different calculation formulae. Graefes Arch Clin Exp Ophthalmol (2006) 1.40
Intense antiextracellular adaptive immune response to human cytomegalovirus in very old subjects with impaired health and cognitive and functional status. J Immunol (2010) 1.34
Ciclopirox: recent nonclinical and clinical data relevant to its use as a topical antimycotic agent. Drugs (2010) 1.33
Role of epigenetics in human aging and longevity: genome-wide DNA methylation profile in centenarians and centenarians' offspring. Age (Dordr) (2012) 1.33
Pharmaceutical agents known to produce disulfiram-like reaction: effects on hepatic ethanol metabolism and brain monoamines. Int J Toxicol (2007) 1.30
The genetics of human longevity. Ann N Y Acad Sci (2006) 1.30
Toward the defined and xeno-free differentiation of functional human pluripotent stem cell-derived retinal pigment epithelial cells. Mol Vis (2011) 1.25
Immune system, cell senescence, aging and longevity--inflamm-aging reappraised. Curr Pharm Des (2013) 1.23
Inflamm-ageing. Curr Opin Clin Nutr Metab Care (2013) 1.20
Age-related differences in the expression of circulating microRNAs: miR-21 as a new circulating marker of inflammaging. Mech Ageing Dev (2012) 1.19
Matrix metalloproteinases and their inhibitors in the chamber angle of normal eyes and patients with primary open-angle glaucoma and exfoliation glaucoma. Graefes Arch Clin Exp Ophthalmol (2006) 1.19
Dose-ranging study of metronomic oral vinorelbine in patients with advanced refractory cancer. Clin Cancer Res (2009) 1.17
Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cells. J Cell Mol Med (2008) 1.14
Long-term immune-endocrine effects of bereavement: relationships with anxiety levels and mood. Psychiatry Res (2003) 1.13
PLGA microspheres for the ocular delivery of a peptide drug, vancomycin using emulsification/spray-drying as the preparation method: in vitro/in vivo studies. Eur J Pharm Biopharm (2004) 1.13
Metabolic signatures of extreme longevity in northern Italian centenarians reveal a complex remodeling of lipids, amino acids, and gut microbiota metabolism. PLoS One (2013) 1.11
A phase II study on the duration and stability of the intraocular pressure-lowering effect and tolerability of Tafluprost compared with latanoprost. J Ocul Pharmacol Ther (2010) 1.05
Dose selection trial of metronomic oral vinorelbine monotherapy in patients with metastatic cancer: a hellenic cooperative oncology group clinical translational study. BMC Cancer (2013) 1.04
Constructing benchmark databases and protocols for medical image analysis: diabetic retinopathy. Comput Math Methods Med (2013) 1.03
Low circulating IGF-I bioactivity is associated with human longevity: findings in centenarians' offspring. Aging (Albany NY) (2012) 1.01
Immunoproteasomes and immunosenescence. Ageing Res Rev (2003) 1.00
Mitochondrial DNA involvement in human longevity. Biochim Biophys Acta (2006) 0.98
Oxidative DNA damage repair and parp 1 and parp 2 expression in Epstein-Barr virus-immortalized B lymphocyte cells from young subjects, old subjects, and centenarians. Rejuvenation Res (2007) 0.98
What studies on human longevity tell us about the risk for cancer in the oldest old: data and hypotheses on the genetics and immunology of centenarians. Exp Gerontol (2002) 0.97
The frequency of Klotho KL-VS polymorphism in a large Italian population, from young subjects to centenarians, suggests the presence of specific time windows for its effect. Biogerontology (2009) 0.97
Revisiting bleomycin from pathophysiology to safe clinical use. Crit Rev Oncol Hematol (2013) 0.96
Malassezia yeasts produce a collection of exceptionally potent activators of the Ah (dioxin) receptor detected in diseased human skin. J Invest Dermatol (2013) 0.96
The impact of mitochondrial DNA on human lifespan: a view from studies on centenarians. Biotechnol J (2008) 0.96
A mouse model for Stickler's syndrome: ocular phenotype of mice carrying a targeted heterozygous inactivation of type II (pro)collagen gene (Col2a1). Exp Eye Res (2006) 0.95
p53 codon 72 alleles influence the response to anticancer drugs in cells from aged people by regulating the cell cycle inhibitor p21WAF1. Cell Cycle (2005) 0.95
p53 codon 72 genotype affects apoptosis by cytosine arabinoside in blood leukocytes. Biochem Biophys Res Commun (2002) 0.95
Age-related modifications in circulating IL-15 levels in humans. Mediators Inflamm (2005) 0.94
Centenarians as super-controls to assess the biological relevance of genetic risk factors for common age-related diseases: a proof of principle on type 2 diabetes. Aging (Albany NY) (2013) 0.94
A detailed behavioral analysis of the acute motor effects of caffeine in the rat: involvement of adenosine A1 and A2A receptors. Psychopharmacology (Berl) (2005) 0.93
Circulating mitochondrial DNA increases with age and is a familiar trait: Implications for "inflamm-aging". Eur J Immunol (2014) 0.93
Heat shock response by EBV-immortalized B-lymphocytes from centenarians and control subjects: a model to study the relevance of stress response in longevity. Exp Gerontol (2004) 0.92
Comparison of nitric oxide donors in lowering intraocular pressure in rabbits: role of cyclic GMP. J Ocul Pharmacol Ther (2002) 0.92
The immune system in the elderly: activation-induced and damage-induced apoptosis. Immunol Res (2004) 0.92
Solid lipid nanoparticles (SLN) as ocular delivery system for tobramycin. Int J Pharm (2002) 0.91
Zinc status, psychological and nutritional assessment in old people recruited in five European countries: Zincage study. Biogerontology (2006) 0.91
Human longevity within an evolutionary perspective: the peculiar paradigm of a post-reproductive genetics. Exp Gerontol (2007) 0.91
Mediterranean diet and plasma concentration of inflammatory markers in old and very old subjects in the ZINCAGE population study. Clin Chem Lab Med (2008) 0.90
The cytotoxic effects of preserved and preservative-free prostaglandin analogs on human corneal and conjunctival epithelium in vitro and the distribution of benzalkonium chloride homologs in ocular surface tissues in vivo. Curr Eye Res (2011) 0.90
Occludin is involved in adhesion, apoptosis, differentiation and Ca2+-homeostasis of human keratinocytes: implications for tumorigenesis. PLoS One (2013) 0.90
Structure and barrier properties of human embryonic stem cell-derived retinal pigment epithelial cells are affected by extracellular matrix protein coating. Tissue Eng Part A (2014) 0.90
Long-term consequences of early maternal deprivation in serotonergic activity and HPA function in adult rat. Neurosci Lett (2010) 0.89
Mitochondrial viability and apoptosis induced by aluminum, mercuric mercury and methylmercury in cell lines of neural origin. Arch Toxicol (2004) 0.89
Geldanamycin increases 4-hydroxynonenal (HNE)-induced cell death in human retinal pigment epithelial cells. Neurosci Lett (2005) 0.89
Zinc deficiency and IL-6 -174G/C polymorphism in old people from different European countries: effect of zinc supplementation. ZINCAGE study. Exp Gerontol (2008) 0.88
Comparison of liposome-encapsulated acyclovir with acyclovir ointment: ocular pharmacokinetics in rabbits. J Ocul Pharmacol Ther (2004) 0.88
Bioactivatable, membrane-permeant analogs of cyclic nucleotides as biological tools for growth control of C6 glioma cells. Biol Chem (2003) 0.87
Generation of hESC-derived retinal pigment epithelium on biopolymer coated polyimide membranes. Biomaterials (2012) 0.87
Phase 1 trial of lipoplatin and gemcitabine as a second-line chemotherapy in patients with nonsmall cell lung carcinoma. Cancer (2008) 0.87
Chronic antigenic load and apoptosis in immunosenescence. Trends Immunol (2005) 0.87
Comparison of simultaneous readings of intraocular pressure in rabbits using Perkins handheld, Tono-Pen XL, and TonoVet tonometers. Graefes Arch Clin Exp Ophthalmol (2006) 0.87
The canonical NF-κB pathway differentially protects normal and human tumor cells from ROS-induced DNA damage. Cell Signal (2012) 0.87
Quality of life along the diabetes continuum: a cross-sectional view of health-related quality of life and general health status in middle-aged and older Finns. Qual Life Res (2014) 0.87
In search of sustainable chemical processes: cloning, recombinant expression, and functional characterization of the 7α- and 7β-hydroxysteroid dehydrogenases from Clostridium absonum. Appl Microbiol Biotechnol (2011) 0.86
Phospholipase A2 in chamber angle of normal eyes and patients with primary open angle glaucoma and exfoliation glaucoma. Mol Vis (2007) 0.86
Serum profiling of healthy aging identifies phospho- and sphingolipid species as markers of human longevity. Aging (Albany NY) (2014) 0.86
A human corneal equivalent constructed from SV40-immortalised corneal cell lines. Altern Lab Anim (2005) 0.86
Strong expression of HSP47 in metaplastic nasal mucosa may predict a poor outcome after primary endoscopic dacryocystorhinostomy: a prospective study. Acta Ophthalmol (2011) 0.85
Age-dependent skewing of X chromosome inactivation appears delayed in centenarians' offspring. Is there a role for allelic imbalance in healthy aging and longevity? Aging Cell (2012) 0.85
Imiquimod in the treatment of eyelid basal cell carcinoma. Acta Ophthalmol Scand (2007) 0.85
Assessment of gene-nutrient interactions on inflammatory status of the elderly with the use of a zinc diet score--ZINCAGE study. J Nutr Biochem (2009) 0.85
Penetration of topically applied levofloxacin 0.5% and ofloxacin 0.3% into the vitreous of the non-inflamed human eye. Graefes Arch Clin Exp Ophthalmol (2006) 0.85
Remodelling of biological parameters during human ageing: evidence for complex regulation in longevity and in type 2 diabetes. Age (Dordr) (2011) 0.85
Effects of different N-trimethyl chitosans on in vitro/in vivo ofloxacin transcorneal permeation. J Pharm Sci (2004) 0.84
Polymorphisms in MT1a gene coding region are associated with longevity in Italian Central female population. Biogerontology (2006) 0.84
Complexity of anti-immunosenescence strategies in humans. Artif Organs (2006) 0.84
Oestradiol potentiates the effects of certain pyrethroid compounds in the MCF7 human breast carcinoma cell line. Altern Lab Anim (2004) 0.84
Comparison of human corneal cell cultures in cytotoxicity testing. ALTEX (2004) 0.84
Coadministration of oxaliplatin does not influence the pharmacokinetics of gemcitabine. Anticancer Drugs (2006) 0.83
Comparison of an immortalized human corneal epithelial cell line and rabbit corneal epithelial cell culture in cytotoxicity testing. J Ocul Pharmacol Ther (2002) 0.83
Geldanamycin activates Hsp70 response and attenuates okadaic acid-induced cytotoxicity in human retinal pigment epithelial cells. Brain Res Mol Brain Res (2005) 0.83
Laser in situ keratomileusis enhancements with the Ziemer FEMTO LDV femtosecond laser following previous LASIK treatments. Graefes Arch Clin Exp Ophthalmol (2012) 0.83
Corneal flap thickness with the Moria M2 single-use head 90 microkeratome. Acta Ophthalmol Scand (2007) 0.83
Individual differences in the effects of cannabinoids on motor activity, dopaminergic activity and DARPP-32 phosphorylation in distinct regions of the brain. Int J Neuropsychopharmacol (2009) 0.83
Glutamate uptake is inhibited by tamoxifen and toremifene in cultured retinal pigment epithelial cells. Pharmacol Toxicol (2002) 0.82