Published in Mol Genet Metab on March 01, 2003
A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth. Mol Cell (2007) 5.99
The regulation and evolution of a genetic switch controlling sexually dimorphic traits in Drosophila. Cell (2008) 2.27
New androgen receptor genomic targets show an interaction with the ETS1 transcription factor. EMBO Rep (2007) 2.17
Structural basis of androgen receptor binding to selective androgen response elements. Proc Natl Acad Sci U S A (2004) 1.97
Endocrine-disrupting potential of bisphenol A, bisphenol A dimethacrylate, 4-n-nonylphenol, and 4-n-octylphenol in vitro: new data and a brief review. Environ Health Perspect (2007) 1.95
Steroidogenesis in the skin: implications for local immune functions. J Steroid Biochem Mol Biol (2013) 1.71
Intronic hormone response elements mediate regulation of FKBP5 by progestins and glucocorticoids. Cell Stress Chaperones (2004) 1.62
ChIPping away at gene regulation. EMBO Rep (2008) 1.54
Diverse roles of androgen receptor (AR) domains in AR-mediated signaling. Nucl Recept Signal (2008) 1.47
Sex-related differences in gene expression in human skeletal muscle. PLoS One (2008) 1.20
Androgens and spermatogenesis: lessons from transgenic mouse models. Philos Trans R Soc Lond B Biol Sci (2010) 1.16
Selective androgen receptor modulators in preclinical and clinical development. Nucl Recept Signal (2008) 1.11
Androgens, progestins, and glucocorticoids induce follicle-stimulating hormone beta-subunit gene expression at the level of the gonadotrope. Mol Endocrinol (2006) 1.10
Loss of androgen receptor-dependent growth suppression by prostate cancer cells can occur independently from acquiring oncogenic addiction to androgen receptor signaling. PLoS One (2010) 1.09
DAX-1, as an androgen-target gene, inhibits aromatase expression: a novel mechanism blocking estrogen-dependent breast cancer cell proliferation. Cell Death Dis (2013) 1.08
Loss of androgen receptor binding to selective androgen response elements causes a reproductive phenotype in a knockin mouse model. Proc Natl Acad Sci U S A (2007) 1.06
Inhibition of cyclin D1 expression by androgen receptor in breast cancer cells--identification of a novel androgen response element. Nucleic Acids Res (2010) 1.06
Direct transcriptional targets of sex steroid hormones in bone. J Cell Biochem (2011) 0.99
A novel androgen receptor-binding element modulates Cdc6 transcription in prostate cancer cells during cell-cycle progression. Nucleic Acids Res (2009) 0.95
Xenoestrogenic activity in blood of European and Inuit populations. Environ Health (2006) 0.92
Repression of androgen receptor activity by HEYL, a third member of the Hairy/Enhancer-of-split-related family of Notch effectors. J Biol Chem (2011) 0.88
Androgen response element of the glycine N-methyltransferase gene is located in the coding region of its first exon. Biosci Rep (2013) 0.87
Zygote arrest 1 gene in pig, cattle and human: evidence of different transcript variants in male and female germ cells. Reprod Biol Endocrinol (2006) 0.86
A computational model of the hypothalamic: pituitary: gonadal axis in female fathead minnows (Pimephales promelas) exposed to 17α-ethynylestradiol and 17β-trenbolone. BMC Syst Biol (2011) 0.85
New insights into the androgen-targeted therapies and epigenetic therapies in prostate cancer. Prostate Cancer (2011) 0.79
Androgen and AR contribute to breast cancer development and metastasis: an insight of mechanisms. Oncogene (2016) 0.78
Androgen/androgen receptor axis maintains and promotes cancer cell stemness through direct activation of Nanog transcription in hepatocellular carcinoma. Oncotarget (2016) 0.77
Suppression of metallothionein 3 gene expression by androgen in LNCaP prostate cancer cells. Biomed Rep (2013) 0.76
Refinement of the androgen response element based on ChIP-Seq in androgen-insensitive and androgen-responsive prostate cancer cell lines. Sci Rep (2016) 0.76
Androgen receptor transcriptionally regulates semaphorin 3C in a GATA2-dependent manner. Oncotarget (2016) 0.75
Comparing the rules of engagement of androgen and glucocorticoid receptors. Cell Mol Life Sci (2017) 0.75
Ca(2+)/Calmodulin-Dependent Protein Kinase II and Androgen Signaling Pathways Modulate MEF2 Activity in Testosterone-Induced Cardiac Myocyte Hypertrophy. Front Pharmacol (2017) 0.75
Fracture risk and zoledronic acid therapy in men with osteoporosis. N Engl J Med (2012) 3.51
A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis. Proc Natl Acad Sci U S A (2004) 3.48
Structural basis of androgen receptor binding to selective androgen response elements. Proc Natl Acad Sci U S A (2004) 1.97
Diverse roles of androgen receptor (AR) domains in AR-mediated signaling. Nucl Recept Signal (2008) 1.47
The hinge region regulates DNA binding, nuclear translocation, and transactivation of the androgen receptor. Cancer Res (2007) 1.35
Sex steroid actions in male bone. Endocr Rev (2014) 1.26
Targeting the BAF57 SWI/SNF subunit in prostate cancer: a novel platform to control androgen receptor activity. Cancer Res (2008) 1.26
The rules of DNA recognition by the androgen receptor. Mol Endocrinol (2010) 1.17
Identification of an androgen response element in intron 8 of the sterol regulatory element-binding protein cleavage-activating protein gene allowing direct regulation by the androgen receptor. J Biol Chem (2004) 1.16
Interplay between two hormone-independent activation domains in the androgen receptor. Cancer Res (2006) 1.10
Loss of androgen receptor binding to selective androgen response elements causes a reproductive phenotype in a knockin mouse model. Proc Natl Acad Sci U S A (2007) 1.06
Evidence for DNA-binding domain--ligand-binding domain communications in the androgen receptor. Mol Cell Biol (2012) 1.03
Looking at nuclear receptors from a new angle. Mol Cell Endocrinol (2013) 1.01
Inhibition of cathepsin K for treatment of osteoporosis. Curr Osteoporos Rep (2012) 1.00
Implications of a polyglutamine tract in the function of the human androgen receptor. Biochem Biophys Res Commun (2003) 0.98
The hinge region in androgen receptor control. Mol Cell Endocrinol (2012) 0.98
Active vitamin D (1,25-dihydroxyvitamin D) and bone health in middle-aged and elderly men: the European Male Aging Study (EMAS). J Clin Endocrinol Metab (2013) 0.98
Androgen receptor (AR) in osteocytes is important for the maintenance of male skeletal integrity: evidence from targeted AR disruption in mouse osteocytes. J Bone Miner Res (2012) 0.98
Dual function of an amino-terminal amphipatic helix in androgen receptor-mediated transactivation through specific and nonspecific response elements. J Biol Chem (2002) 0.95
Squalene synthase, a determinant of Raft-associated cholesterol and modulator of cancer cell proliferation. J Biol Chem (2007) 0.95
A 629RKLKK633 motif in the hinge region controls the androgen receptor at multiple levels. Cell Mol Life Sci (2010) 0.93
Once-yearly zoledronic acid in older men compared with women with recent hip fracture. J Am Geriatr Soc (2011) 0.92
Characterization of the two coactivator-interacting surfaces of the androgen receptor and their relative role in transcriptional control. J Biol Chem (2002) 0.92
Osteoporosis in older men: recent advances in pathophysiology and treatment. Best Pract Res Clin Endocrinol Metab (2013) 0.92
Androgens and skeletal muscle: cellular and molecular action mechanisms underlying the anabolic actions. Cell Mol Life Sci (2011) 0.91
Superagonistic action of 14-epi-analogs of 1,25-dihydroxyvitamin D explained by vitamin D receptor-coactivator interaction. Mol Pharmacol (2005) 0.91
Structural basis for nuclear hormone receptor DNA binding. Mol Cell Endocrinol (2011) 0.90
Functional interplay between two response elements with distinct binding characteristics dictates androgen specificity of the mouse sex-limited protein enhancer. J Biol Chem (2002) 0.89
The genomic landscape of prostate cancer. Int J Mol Sci (2013) 0.88
Novel insights in the regulation and mechanism of androgen action on bone. Curr Opin Endocrinol Diabetes Obes (2013) 0.87
Androgen regulation of the TMPRSS2 gene and the effect of a SNP in an androgen response element. Mol Endocrinol (2013) 0.87
Variations in the exome of the LNCaP prostate cancer cell line. Prostate (2011) 0.87
DNA demethylation-dependent AR recruitment and GATA factors drive Rhox5 homeobox gene transcription in the epididymis. Mol Endocrinol (2012) 0.87
DNA recognition by the androgen receptor: evidence for an alternative DNA-dependent dimerization, and an active role of sequences flanking the response element on transactivation. Biochem J (2003) 0.86
Expression of Tubb3, a beta-tubulin isotype, is regulated by androgens in mouse and rat Sertoli cells. Biol Reprod (2011) 0.86
The hinge region of the androgen receptor plays a role in proteasome-mediated transcriptional activation. Ann N Y Acad Sci (2004) 0.86
Regulation of androgen receptor-dependent transcription by coactivator MED1 is mediated through a newly discovered noncanonical binding motif. J Biol Chem (2011) 0.86
Sensitive routine liquid chromatography-tandem mass spectrometry method for serum estradiol and estrone without derivatization. Anal Bioanal Chem (2013) 0.85
Androgens inhibit the osteogenic response to mechanical loading in adult male mice. Endocrinology (2015) 0.84
Associations between sex steroids and the development of metabolic syndrome: a longitudinal study in European men. J Clin Endocrinol Metab (2015) 0.84
NBBS isolated from Pygeum africanum bark exhibits androgen antagonistic activity, inhibits AR nuclear translocation and prostate cancer cell growth. Invest New Drugs (2009) 0.81
Testosterone and the male skeleton: a dual mode of action. J Osteoporos (2011) 0.81
Influence of bone remodelling rate on quantitative ultrasound parameters at the calcaneus and DXA BMDa of the hip and spine in middle-aged and elderly European men: the European Male Ageing Study (EMAS). Eur J Endocrinol (2011) 0.81
Androgen receptor uses relaxed response element stringency for selective chromatin binding and transcriptional regulation in vivo. Nucleic Acids Res (2014) 0.81
Agonist-antagonist induced coactivator and corepressor interplay on the human androgen receptor. Mol Cell Endocrinol (2003) 0.80
Calcium and vitamin d supplementation in men. J Osteoporos (2011) 0.79
Time to onset of antifracture efficacy and year-by-year persistence of effect of zoledronic acid in women with osteoporosis. J Bone Miner Res (2012) 0.79
A role for selective androgen response elements in the development of the epididymis and the androgen control of the 5α reductase II gene. FASEB J (2012) 0.78
Healthy birth after testicular extraction of sperm and ICSI from an azoospermic man with mild androgen insensitivity syndrome caused by an androgen receptor partial loss-of-function mutation. Clin Endocrinol (Oxf) (2012) 0.78
Identification of androgen-selective androgen-response elements in the human aquaporin-5 and Rad9 genes. Biochem J (2008) 0.78
The natural compound atraric acid is an antagonist of the human androgen receptor inhibiting cellular invasiveness and prostate cancer cell growth. J Cell Mol Med (2009) 0.77
Identification and characterization of androgen response elements. Methods Mol Biol (2011) 0.77
Comparison of different androgen bioassays in the screening for environmental (anti)androgenic activity. Environ Toxicol Chem (2005) 0.76
The discovery of novel human androgen receptor antagonist chemotypes using a combined pharmacophore screening procedure. ChemMedChem (2013) 0.76
Identification and characterization of MEL-3, a novel AR antagonist that suppresses prostate cancer cell growth. Mol Cancer Ther (2012) 0.76
Altered Vitamin D receptor-coactivator interactions reflect superagonism of Vitamin D analogs. J Steroid Biochem Mol Biol (2005) 0.75