Published in Science on May 21, 1976
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Mechanism of frequency-dependent broadening of molluscan neurone soma spikes. J Physiol (1979) 1.97
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Sodium and calcium gating currents in an Aplysia neurone. J Physiol (1979) 1.22
Activation kinetics of calcium currents in bull-frog sympathetic neurones. J Physiol (1991) 0.94
Capacitance of the surface and transverse tubular membrane of frog sartorius muscle fibers. J Gen Physiol (1969) 5.50
Ionic conductances of the surface and transverse tubular membranes of frog sartorius fibers. J Gen Physiol (1969) 5.45
The permeability of the endplate channel to organic cations in frog muscle. J Gen Physiol (1980) 5.00
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Characteristics of sodium and calcium conductance changes produced by membrane depolarization in an Aplysia neurone. J Physiol (1979) 2.06
The Vpu protein of human immunodeficiency virus type 1 forms cation-selective ion channels. J Virol (1996) 2.01
Block of endplate channels by permeant cations in frog skeletal muscle. J Gen Physiol (1981) 2.00
A persistent sodium current in rat ventricular myocytes. J Physiol (1992) 1.95
Effects of some aliphatic alcohols on the conductance change caused by a quantum of acetylcholine at the toad end-plate. J Physiol (1975) 1.92
Electrical properties of toad sartorius muscle fibres in summer and winter. J Physiol (1973) 1.90
Phasic secretion of acetylcholine at a mammalian neuromuscular junction. J Physiol (1980) 1.90
Hypoxia increases persistent sodium current in rat ventricular myocytes. J Physiol (1996) 1.83
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Calcium entry through receptor-operated channels in bovine pulmonary artery endothelial cells. Tissue Cell (1987) 1.74
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An investigation of the post-tetanic potentiation of end-plate potentials at a mammalian neuromuscular junction. J Physiol (1966) 1.70
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Asymmetrical charge movement in slow- and fast-twitch mammalian muscle fibres in normal and paraplegic rats. J Physiol (1983) 1.60
Permeant cations alter endplate channel characteristics. Nature (1977) 1.59
Dual effect of potassium on transmitter release. Nature (1965) 1.57
Hippocampal GABA(A) channel conductance increased by diazepam. Nature (1997) 1.54
Transmission across the squid giant synapse in the presence of tetrodotoxin. J Physiol (1967) 1.54
Evidence for a Poisson distribution of miniature end-plate potentials and some implications. Nature (1965) 1.51
An analysis of the relationship between the current and potential generated by a quantum of acetylcholine in muscle fibers without transverse tubules. J Membr Biol (1973) 1.51
The origin of the post-tetanic hyperpolarization of mammalian motor nerve terminals. J Physiol (1966) 1.50
Calcium-activated potassium channels in native endothelial cells from rabbit aorta: conductance, Ca2+ sensitivity and block. J Physiol (1992) 1.49
Octanol reduces end-plate channel lifetime. J Physiol (1978) 1.48
Cellular heterogeneity and drug resistance in two ovarian adenocarcinoma cell lines derived from a single patient. Int J Cancer (1987) 1.47
The activating mutation R201C in GNAS promotes intestinal tumourigenesis in Apc(Min/+) mice through activation of Wnt and ERK1/2 MAPK pathways. Oncogene (2010) 1.45
Excitation-contraction coupling and charge movement in denervated rat extensor digitorum longus and soleus muscles. J Physiol (1985) 1.44
Vpr protein of human immunodeficiency virus type 1 forms cation-selective channels in planar lipid bilayers. Proc Natl Acad Sci U S A (1996) 1.44
The effect of methyl, ethyl and n-propyl alcohol on neuromuscular transmission in the rat. J Pharmacol Exp Ther (1965) 1.43
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The RASSF1A isoform of RASSF1 promotes microtubule stability and suppresses tumorigenesis. Mol Cell Biol (2005) 1.40
Endplate currents are shortened by octanol: possible role of membrane lipid. Life Sci (1974) 1.36
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Acetylcholine-evoked currents in cultured neurones dissociated from rat parasympathetic cardiac ganglia. J Physiol (1991) 1.35
Ionic currents in response to membrane depolarization in an Aplysia neurone. J Physiol (1979) 1.34
A threshold sodium current in pyramidal cells in rat hippocampus. Neurosci Lett (1985) 1.33
The role of the electrochemical gradient in determining potassium fluxes in frog striated muscle. J Gen Physiol (1968) 1.30
Prolongation of inhibitory postsynaptic currents by pentobarbitone, halothane and ketamine in CA1 pyramidal cells in rat hippocampus. Br J Pharmacol (1985) 1.29
Effects of several inhalation anaesthetics on the kinetics of postsynaptic conductance changes in mouse diaphragm. Br J Pharmacol (1976) 1.29
The relationship of brevetoxin 'length' and A-ring functionality to binding and activity in neuronal sodium channels. Chem Biol (1995) 1.28
Interaction of azole antifungal antibiotics with cytochrome P-450-dependent 14 alpha-sterol demethylase purified from Candida albicans. Biochem J (1990) 1.27
muO-conotoxin MrVIB selectively blocks Nav1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficits. Proc Natl Acad Sci U S A (2006) 1.26
Synaptic current at the squid giant synapse. Science (1969) 1.26
Differential effects of glycerol treatment on membrane capacity and excitation-contraction coupling in toad sartorius fibres. J Physiol (1973) 1.26
Paralysis of skeletal muscle by butanedione monoxime, a chemical phosphatase. Pflugers Arch (1988) 1.24
Synchronized oscillations in cytoplasmic free calcium concentration in confluent bradykinin-stimulated bovine pulmonary artery endothelial cell monolayers. J Biol Chem (1989) 1.23
Novel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes. J Biol Chem (2000) 1.23
Membrane potential and Na(+)-K+ pump activity modulate resting and bradykinin-stimulated changes in cytosolic free calcium in cultured endothelial cells from bovine atria. J Biol Chem (1990) 1.23
The inhibitory effect of manganese on transmitter release at the neuromuscular junction of the toad. Br J Pharmacol (1973) 1.23
Sodium and calcium gating currents in an Aplysia neurone. J Physiol (1979) 1.22
Interaction of internal anions with potassium channels of the squid giant axon. J Gen Physiol (1983) 1.22
Estrogen induced synthesis of specific proteins in human breast cancer cells. Biochem Biophys Res Commun (1980) 1.22
Postsynaptic effect of i.v. anaesthetic agents at the neuromuscular junction. Br J Anaesth (1977) 1.22
On facilitation of transmitter release at the toad neuromuscular junction. J Physiol (1974) 1.21
Effects of extracellular calcium concentration and dihydropyridines on contraction in mammalian skeletal muscle. J Physiol (1988) 1.20
Lithium stimulates secretion of acetylcholine in the absence of extracellular calcium. Brain Res (1973) 1.18
Differential effects of perhydrohistrionicotoxin on neurally and iontophoretically evoked endplate currents. Proc Natl Acad Sci U S A (1978) 1.17
Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter. Nat Neurosci (2001) 1.17
The identification of Candida albicans strains by restriction fragment length polymorphism analysis of DNA. J Med Vet Mycol (1989) 1.17
Characteristics of two types of chloride channel in sarcoplasmic reticulum vesicles from rabbit skeletal muscle. Biophys J (1996) 1.17
Estrogen regulation of specific messinger RNA's in human breast cancer cells. Biochem Biophys Res Commun (1980) 1.16
Effects of lignocaine and quinidine on the persistent sodium current in rat ventricular myocytes. Br J Pharmacol (1992) 1.15
Attenuation of signaling pathways stimulated by pathologically activated FGF-receptor 2 mutants prevents craniosynostosis. Proc Natl Acad Sci U S A (2006) 1.15
Ion channels formed by NB, an influenza B virus protein. J Membr Biol (1996) 1.15
The Oxford hip and knee outcome questionnaires for arthroplasty. J Bone Joint Surg Br (2005) 1.14
Inhibitors of calcium buffering depress evoked transmitter release at the squid giant synapse. J Physiol (1985) 1.13
Cytochrome P-450-dependent 14 alpha-demethylation of lanosterol in Candida albicans. Biochem J (1989) 1.13
Distribution of an estrogen-induced protein with a molecular weight of 24,000 in normal and malignant human tissues and cells. Cancer Res (1983) 1.13
Monovalent and divalent cation permeability and block of neuronal nicotinic receptor channels in rat parasympathetic ganglia. J Gen Physiol (1995) 1.12
Voltage sensitivity of inhibitory postsynaptic current in Aplysia buccal ganglia. Brain Res (1976) 1.09
A new, sensitive polynucleotide probe for distinguishing Candida albicans strains and its use with a computer assisted archiving and pattern comparison system. J Med Vet Mycol (1992) 1.09
The amino-terminal region of Vpr from human immunodeficiency virus type 1 forms ion channels and kills neurons. J Virol (1999) 1.08
Extracellular HIV-1 virus protein R causes a large inward current and cell death in cultured hippocampal neurons: implications for AIDS pathology. Proc Natl Acad Sci U S A (1998) 1.08
Inhibitory postsynaptic currents at Aplysia cholinergic synapses: effects of permeant anions and depressant drugs. Proc R Soc Lond B Biol Sci (1982) 1.08