1
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2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference.
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Crit Care Med
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2003
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28.68
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2
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Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock.
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Crit Care Med
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2004
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24.47
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3
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2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference.
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Intensive Care Med
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2003
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10.39
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4
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Drotrecogin alfa (activated) in adults with septic shock.
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N Engl J Med
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2012
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9.19
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5
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The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis.
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Crit Care Med
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2010
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6.69
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6
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Association of hydroxyethyl starch administration with mortality and acute kidney injury in critically ill patients requiring volume resuscitation: a systematic review and meta-analysis.
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JAMA
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2013
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5.98
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7
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Sepsis definitions: time for change.
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Lancet
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2013
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5.63
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8
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No surgical innovation without evaluation: the IDEAL recommendations.
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Lancet
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2009
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5.57
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9
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The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis.
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Intensive Care Med
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2010
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4.64
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10
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Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock.
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Intensive Care Med
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2004
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4.56
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11
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Design, conduct, analysis and reporting of a multi-national placebo-controlled trial of activated protein C for persistent septic shock.
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Intensive Care Med
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2008
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4.21
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12
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Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome.
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JAMA
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2003
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3.69
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13
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Efficacy and safety of the monoclonal anti-tumor necrosis factor antibody F(ab')2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels.
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Crit Care Med
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2004
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3.61
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14
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Evaluation and stages of surgical innovations.
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Lancet
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2009
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3.04
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15
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Challenges in evaluating surgical innovation.
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Lancet
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2009
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2.86
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16
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Ten reasons why we should NOT use severity scores as entry criteria for clinical trials or in our treatment decisions.
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Crit Care Med
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2010
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2.83
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17
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Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials.
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PLoS One
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2.75
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18
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Pre-B cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis.
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J Clin Invest
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2004
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2.72
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19
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Lateralized cognitive processes and lateralized task control in the human brain.
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Science
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2003
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2.62
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20
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Age of transfused blood in critically ill adults.
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N Engl J Med
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2015
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2.52
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21
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Integrating mortality and morbidity outcomes: using quality-adjusted life years in critical care trials.
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Am J Respir Crit Care Med
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2012
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2.15
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22
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Analysis of neural mechanisms underlying verbal fluency in cytoarchitectonically defined stereotaxic space--the roles of Brodmann areas 44 and 45.
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Neuroimage
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2004
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2.10
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23
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Oxidative stress generated by hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages.
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J Exp Med
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2006
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2.07
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24
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Delayed neutrophil apoptosis in sepsis is associated with maintenance of mitochondrial transmembrane potential and reduced caspase-9 activity.
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Crit Care Med
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2004
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1.90
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25
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Pre-B cell colony-enhancing factor (PBEF)/visfatin: a novel mediator of innate immunity.
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J Leukoc Biol
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2008
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1.87
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26
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Effect of a liberal versus restrictive transfusion strategy on mortality in patients with moderate to severe head injury.
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Neurocrit Care
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2006
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1.87
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27
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Modulation of gonadotropin-releasing hormone pulse generator sensitivity to progesterone inhibition in hyperandrogenic adolescent girls--implications for regulation of pubertal maturation.
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J Clin Endocrinol Metab
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1.82
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28
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Increased mortality associated with methicillin-resistant Staphylococcus aureus (MRSA) infection in the intensive care unit: results from the EPIC II study.
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Int J Antimicrob Agents
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2011
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1.80
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29
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Interhemispheric integration of visual processing during task-driven lateralization.
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J Neurosci
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2007
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1.78
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30
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Using fMRI to decompose the neural processes underlying the Wisconsin Card Sorting Test.
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Neuroimage
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2006
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1.77
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31
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The Age of Blood Evaluation (ABLE) randomized controlled trial: study design.
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Transfus Med Rev
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2011
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1.71
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32
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Research recruitment practices and critically ill patients. A multicenter, cross-sectional study (the Consent Study).
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Am J Respir Crit Care Med
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1.63
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33
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Empiric antibiotic therapy for suspected ventilator-associated pneumonia: a systematic review and meta-analysis of randomized trials.
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2008
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1.61
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34
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Obesity and sex steroid changes across puberty: evidence for marked hyperandrogenemia in pre- and early pubertal obese girls.
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2006
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1.55
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35
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Impact of selective decontamination of the digestive tract on multiple organ dysfunction syndrome: systematic review of randomized controlled trials.
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1.55
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36
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Evaluating the use of recombinant human activated protein C in adult severe sepsis: results of the Surviving Sepsis Campaign.
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Crit Care Med
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2012
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1.51
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37
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Low-dose corticosteroid treatment in septic shock: a propensity-matching study.
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Crit Care Med
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2014
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1.50
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38
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Discordance between perception and treatment practices associated with intensive care unit-acquired bacteriuria and funguria: a Canadian physician survey.
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Crit Care Med
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1.48
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39
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The association of obesity and hyperandrogenemia during the pubertal transition in girls: obesity as a potential factor in the genesis of postpubertal hyperandrogenism.
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J Clin Endocrinol Metab
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2006
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1.46
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40
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Neutralization of tumor necrosis factor in preclinical models of sepsis.
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1.45
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41
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Neurophysiological correlates of relatively enhanced local visual search in autistic adolescents.
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Neuroimage
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1.45
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42
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1.39
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43
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Crit Care Med
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1.39
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44
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Estimation of estradiol in mouse serum samples: evaluation of commercial estradiol immunoassays.
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Endocrinology
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2011
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1.31
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45
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Performing allocentric visuospatial judgments with induced distortion of the egocentric reference frame: an fMRI study with clinical implications.
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Neuroimage
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1.28
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Maturation of luteinizing hormone (gonadotropin-releasing hormone) secretion across puberty: evidence for altered regulation in obese peripubertal girls.
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1.20
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47
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1.20
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48
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49
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50
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1.13
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51
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Posterior parietal cortex is implicated in continuous switching between verbal fluency tasks: an fMRI study with clinical implications.
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1.12
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52
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53
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Regulation of Toll-like receptor 4 expression in the lung following hemorrhagic shock and lipopolysaccharide.
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56
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60
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Mechanisms of hemispheric specialization: insights from analyses of connectivity.
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67
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