Published in Arterioscler Thromb Vasc Biol on April 10, 2003
Signaling during platelet adhesion and activation. Arterioscler Thromb Vasc Biol (2010) 2.43
Vascularization strategies for tissue engineering. Tissue Eng Part B Rev (2009) 2.31
Human peripheral blood-derived CD31+ cells have robust angiogenic and vasculogenic properties and are effective for treating ischemic vascular disease. J Am Coll Cardiol (2010) 1.92
Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels. Am J Pathol (2009) 1.87
Site-specific effects of PECAM-1 on atherosclerosis in LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol (2008) 1.78
Enhanced susceptibility to endotoxic shock and impaired STAT3 signaling in CD31-deficient mice. Am J Pathol (2005) 1.65
A CD31-derived peptide prevents angiotensin II-induced atherosclerosis progression and aneurysm formation. Cardiovasc Res (2012) 1.63
Minding the gaps to promote thrombus growth and stability. J Clin Invest (2005) 1.53
PECAM-1: conflicts of interest in inflammation. Life Sci (2010) 1.30
Breaking down the barrier: the effects of HIV-1 on the blood-brain barrier. Brain Res (2011) 1.29
Expression of genes encoding innate host defense molecules in normal human monocytes in response to Candida albicans. Infect Immun (2005) 1.24
Effect of antibodies on endothelium. Am J Transplant (2009) 1.23
Regulating thrombus growth and stability to achieve an optimal response to injury. J Thromb Haemost (2011) 1.20
Angiogenesis in platelet endothelial cell adhesion molecule-1-null mice. Am J Pathol (2009) 1.18
Alpha2,6-sialic acid on platelet endothelial cell adhesion molecule (PECAM) regulates its homophilic interactions and downstream antiapoptotic signaling. J Biol Chem (2010) 1.16
TCR stimulation drives cleavage and shedding of the ITIM receptor CD31. J Immunol (2010) 1.15
Ig gene-like molecule CD31 plays a nonredundant role in the regulation of T-cell immunity and tolerance. Proc Natl Acad Sci U S A (2010) 1.11
Vascular endothelial platelet endothelial cell adhesion molecule 1 (PECAM-1) regulates advanced metastatic progression. Proc Natl Acad Sci U S A (2010) 1.07
Monocyte trafficking across the vessel wall. Cardiovasc Res (2015) 1.06
PECAM-1: regulator of endothelial junctional integrity. Cell Tissue Res (2014) 1.05
Assessing angiogenesis during fracture healing. Iowa Orthop J (2006) 1.04
Online nanoflow multidimensional fractionation for high efficiency phosphopeptide analysis. Mol Cell Proteomics (2011) 1.02
The alleles of PECAM-1. Gene (2006) 1.00
Platelet signaling. Handb Exp Pharmacol (2012) 0.99
Collaborative enhancement of antibody binding to distinct PECAM-1 epitopes modulates endothelial targeting. PLoS One (2012) 0.98
Relative contribution of PECAM-1 adhesion and signaling to the maintenance of vascular integrity. J Cell Sci (2011) 0.96
Residues within a lipid-associated segment of the PECAM-1 cytoplasmic domain are susceptible to inducible, sequential phosphorylation. Blood (2011) 0.95
Lyn and PECAM-1 function as interdependent inhibitors of platelet aggregation. Blood (2011) 0.95
PECAM-1 regulates proangiogenic properties of endothelial cells through modulation of cell-cell and cell-matrix interactions. Am J Physiol Cell Physiol (2010) 0.95
CD31 is required on CD4+ T cells to promote T cell survival during Salmonella infection. J Immunol (2011) 0.93
Immunoreceptor tyrosine-based inhibitory motif (ITIM)-mediated inhibitory signaling is regulated by sequential phosphorylation mediated by distinct nonreceptor tyrosine kinases: a case study involving PECAM-1. Biochemistry (2013) 0.91
Human aging and CD31+ T-cell number, migration, apoptotic susceptibility, and telomere length. J Appl Physiol (1985) (2010) 0.90
PECAM-1 engagement counteracts ICAM-1-induced signaling in brain vascular endothelial cells. J Neurochem (2007) 0.89
Human haemodynamic frequency harmonics regulate the inflammatory phenotype of vascular endothelial cells. Nat Commun (2013) 0.89
PECAM-1 isoform-specific functions in PECAM-1-deficient brain microvascular endothelial cells. Microvasc Res (2007) 0.89
Paired immunoglobulin-like receptor B regulates platelet activation. Blood (2014) 0.89
Non-invasive diagnosis of early pulmonary disease in PECAM-deficient mice using infrared pulse oximetry. Exp Mol Pathol (2009) 0.88
Vascular development and hemodynamic force in the mouse yolk sac. Front Physiol (2014) 0.88
Interactions between blood-borne Streptococcus pneumoniae and the blood-brain barrier preceding meningitis. PLoS One (2013) 0.88
Migration of polymorphonuclear leucocytes is influenced by dendritic cells. Immunology (2005) 0.88
A novel role for PECAM-1 (CD31) in regulating haematopoietic progenitor cell compartmentalization between the peripheral blood and bone marrow. PLoS One (2008) 0.88
The Y's that bind: negative regulators of Src family kinase activity in platelets. J Thromb Haemost (2009) 0.87
Platelet endothelial cell adhesion molecule-1 regulates collagen-stimulated platelet function by modulating the association of phosphatidylinositol 3-kinase with Grb-2-associated binding protein-1 and linker for activation of T cells. J Thromb Haemost (2010) 0.86
NEU1 sialidase regulates the sialylation state of CD31 and disrupts CD31-driven capillary-like tube formation in human lung microvascular endothelia. J Biol Chem (2014) 0.86
PECAM-1 isoforms, eNOS and endoglin axis in regulation of angiogenesis. Clin Sci (Lond) (2015) 0.85
PECAM-1: a multifaceted regulator of megakaryocytopoiesis. Blood (2007) 0.84
CD31 signals confer immune privilege to the vascular endothelium. Proc Natl Acad Sci U S A (2015) 0.84
In vitro behaviour of endothelial cells on a titanium surface. Head Face Med (2008) 0.84
Phosphorylation of leukocyte PECAM and its association with detergent-resistant membranes regulate transendothelial migration. J Immunol (2010) 0.84
Levels of soluble platelet endothelial cell adhesion molecule-1 and P-selectin are decreased in children with autism spectrum disorder. Biol Psychiatry (2012) 0.84
An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling. J Cell Sci (2008) 0.83
Primed T cell responses to chemokines are regulated by the immunoglobulin-like molecule CD31. PLoS One (2012) 0.83
Endothelial functions of platelet/endothelial cell adhesion molecule-1 (CD31). Curr Opin Hematol (2016) 0.83
Hedgehog signaling in the posterior region of the mouse gastrula suggests manifold roles in the fetal-umbilical connection and posterior morphogenesis. Dev Dyn (2011) 0.82
The anti-inflammatory actions of platelet endothelial cell adhesion molecule-1 do not involve regulation of endothelial cell NF-kappa B. J Immunol (2010) 0.82
PECAM-1 dampens cytokine levels during LPS-induced endotoxemia by regulating leukocyte trafficking. Life Sci (2011) 0.82
Harnessing the platelet signaling network to produce an optimal hemostatic response. Hematol Oncol Clin North Am (2013) 0.82
Interaction of platelet endothelial cell adhesion molecule (PECAM) with α2,6-sialylated glycan regulates its cell surface residency and anti-apoptotic role. J Biol Chem (2014) 0.81
Phosphorylation and localization of protein-zero related (PZR) in cultured endothelial cells. Endothelium (2008) 0.81
Platelet endothelial cell adhesion molecule-1, a putative receptor for the adhesion of Streptococcus pneumoniae to the vascular endothelium of the blood-brain barrier. Infect Immun (2014) 0.81
Structural basis for PECAM-1 homophilic binding. Blood (2015) 0.80
Mapping mouse hemangioblast maturation from headfold stages. Dev Biol (2012) 0.80
QHREDGS enhances tube formation, metabolism and survival of endothelial cells in collagen-chitosan hydrogels. PLoS One (2013) 0.80
Elevated tricuspid regurgitant jet velocity in subgroups of thalassemia patients: insight into pathophysiology and the effect of splenectomy. Ann Hematol (2014) 0.79
Toxic damage increases angiogenesis and metastasis in fibrotic livers via PECAM-1. Biomed Res Int (2014) 0.79
Flow shear stress differentially regulates endothelial uptake of nanocarriers targeted to distinct epitopes of PECAM-1. J Control Release (2015) 0.79
Cloning and Stable Expression of cDNA Coding For Platelet Endothelial Cell Adhesion Molecule -1 (PECAM-1, CD31) in NIH-3T3 Cell Line. Adv Pharm Bull (2015) 0.79
Mechanosignaling in the vasculature: emerging concepts in sensing, transduction and physiological responses. Am J Physiol Heart Circ Physiol (2015) 0.78
PECAM-1 is involved in BCR/ABL signaling and may downregulate imatinib-induced apoptosis of Philadelphia chromosome-positive leukemia cells. Int J Oncol (2012) 0.78
Activation of Vascular Endothelial Growth Factor (VEGF) Receptor 2 Mediates Endothelial Permeability Caused by Cyclic Stretch. J Biol Chem (2016) 0.78
Esophageal squamous cell carcinoma: assessing tumor angiogenesis using multi-slice CT perfusion imaging. Dig Dis Sci (2012) 0.78
CD44: target for antiangiogenesis therapy. Blood (2009) 0.77
Vascular endothelial growth factor (VEGF) and platelet (PF-4) factor 4 inputs modulate human microvascular endothelial signaling in a three-dimensional matrix migration context. Mol Cell Proteomics (2013) 0.77
Asn563Ser polymorphism of CD31/PECAM-1 is associated with atherosclerotic cerebral infarction in a southern Han population. Neuropsychiatr Dis Treat (2014) 0.77
sPECAM-1 and sVCAM-1: Role in Pathogenesis and Diagnosis of Chronic Hepatitis C and Association with Response to Antiviral Therapy. Therap Adv Gastroenterol (2009) 0.77
ApoA-I induced CD31 in bone marrow-derived vascular progenitor cells increases adhesion: implications for vascular repair. Biochim Biophys Acta (2008) 0.76
The adhesion molecule PECAM-1 enhances the TGF-β-mediated inhibition of T cell function. Sci Signal (2016) 0.76
Platelets in pulmonary vascular physiology and pathology. Pulm Circ (2012) 0.76
Inhibition of lung tumor growth in nude mice by siRNA(CD31) targeting PECAM-1. Oncol Lett (2014) 0.76
The Role of Sialylated Glycans in Human Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1)-mediated Trans Homophilic Interactions and Endothelial Cell Barrier Function. J Biol Chem (2016) 0.75
Transendothelial migration: unifying principles from the endothelial perspective. Immunol Rev (2016) 0.75
Preeclampsia does not alter vascular growth and expression of CD31 and vascular endothelial cadherin in human placentas. J Histochem Cytochem (2014) 0.75
Seminal CD38 Enhances Human Sperm Capacitation through Its Interaction with CD31. PLoS One (2015) 0.75
Biochemical and Functional Insights into the Integrated Regulation of Innate Immune Cell Responses by Teleost Leukocyte Immune-Type Receptors. Biology (Basel) (2016) 0.75
Unreported intrinsic disorder in proteins: Building connections to the literature on IDPs. Intrinsically Disord Proteins (2014) 0.75
Structural Basis for Human PECAM-1-Mediated Trans-homophilic Cell Adhesion. Sci Rep (2016) 0.75
Soothing touch of CD31 protects endothelium during cellular immune responses. Proc Natl Acad Sci U S A (2015) 0.75
Nitric oxide modulates lipopolysaccharide-induced endothelial platelet endothelial cell adhesion molecule expression via interleukin-10. Clin Exp Immunol (2011) 0.75
Distinct sites within the vascular cell adhesion molecule-1 (VCAM-1) cytoplasmic domain regulate VCAM-1 activation of calcium fluxes versus Rac1 during leukocyte transendothelial migration. Biochemistry (2012) 0.75
Mechanotransduction Effects on Endothelial Cell Proliferation via CD31 and VEGFR2: Implications for Immunomagnetic Separation. Biotechnol J (2017) 0.75
Site-specific effects of PECAM-1 on atherosclerosis in LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol (2008) 1.78
High-throughput phosphotyrosine profiling using SH2 domains. Mol Cell (2007) 1.72
Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo. Blood (2012) 1.72
The cell-adhesion and signaling molecule PECAM-1 is a molecular mediator of resistance to genotoxic chemotherapy. Cancer Biol Ther (2006) 1.65
Heparin promotes platelet responsiveness by potentiating αIIbβ3-mediated outside-in signaling. Blood (2011) 1.59
Identification of FcgammaRIIa as the ITAM-bearing receptor mediating alphaIIbbeta3 outside-in integrin signaling in human platelets. Blood (2008) 1.54
Platelet PECAM-1 inhibits thrombus formation in vivo. Blood (2005) 1.53
Endothelial cell PECAM-1 confers protection against endotoxic shock. Am J Physiol Heart Circ Physiol (2004) 1.44
PECAM-1 functions as a specific and potent inhibitor of mitochondrial-dependent apoptosis. Blood (2003) 1.33
PECAM-1: conflicts of interest in inflammation. Life Sci (2010) 1.30
Eptifibatide-induced thrombocytopenia and thrombosis in humans require FcgammaRIIa and the integrin beta3 cytoplasmic domain. J Clin Invest (2009) 1.24
TCR stimulation drives cleavage and shedding of the ITIM receptor CD31. J Immunol (2010) 1.15
Peroxynitrite reduces the endothelium-derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knockout mice. Am J Physiol Regul Integr Comp Physiol (2005) 1.05
PECAM-1 negatively regulates GPIb/V/IX signaling in murine platelets. Blood (2003) 1.01
The alleles of PECAM-1. Gene (2006) 1.00
Platelet signaling. Handb Exp Pharmacol (2012) 0.99
Paxillin family members function as Csk-binding proteins that regulate Lyn activity in human and murine platelets. Biochem J (2007) 0.98
Neutrophil transmigration mediated by the neutrophil-specific antigen CD177 is influenced by the endothelial S536N dimorphism of platelet endothelial cell adhesion molecule-1. J Immunol (2010) 0.98
The proinflammatory phenotype of PECAM-1-deficient mice results in atherogenic diet-induced steatohepatitis. Am J Physiol Gastrointest Liver Physiol (2007) 0.97
Relative contribution of PECAM-1 adhesion and signaling to the maintenance of vascular integrity. J Cell Sci (2011) 0.96
Residues within a lipid-associated segment of the PECAM-1 cytoplasmic domain are susceptible to inducible, sequential phosphorylation. Blood (2011) 0.95
Lyn and PECAM-1 function as interdependent inhibitors of platelet aggregation. Blood (2011) 0.95
A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling. Blood (2011) 0.93
Phospholipase Cgamma2 contributes to stable thrombus formation on VWF. FEBS Lett (2004) 0.93
Critical role for mouse marginal zone B cells in PF4/heparin antibody production. Blood (2013) 0.91
Immunoreceptor tyrosine-based inhibitory motif (ITIM)-mediated inhibitory signaling is regulated by sequential phosphorylation mediated by distinct nonreceptor tyrosine kinases: a case study involving PECAM-1. Biochemistry (2013) 0.91
An important role of phospholipase Cgamma1 in pre-B-cell development and allelic exclusion. EMBO J (2004) 0.90
Reactive oxygen species induce reversible PECAM-1 tyrosine phosphorylation and SHP-2 binding. Am J Physiol Heart Circ Physiol (2003) 0.88
Mechanism of outside-in {alpha}IIb{beta}3-mediated activation of human platelets by the colonizing Bacterium, Streptococcus gordonii. Arterioscler Thromb Vasc Biol (2010) 0.85
B-cell tolerance regulates production of antibodies causing heparin-induced thrombocytopenia. Blood (2013) 0.84
An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling. J Cell Sci (2008) 0.83
The anti-inflammatory actions of platelet endothelial cell adhesion molecule-1 do not involve regulation of endothelial cell NF-kappa B. J Immunol (2010) 0.82
PECAM-1 dampens cytokine levels during LPS-induced endotoxemia by regulating leukocyte trafficking. Life Sci (2011) 0.82
Cadherin 6 has a functional role in platelet aggregation and thrombus formation. Arterioscler Thromb Vasc Biol (2012) 0.80