Published in J Cell Physiol on June 01, 2003
High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet (2008) 9.68
AU-rich elements and associated factors: are there unifying principles? Nucleic Acids Res (2006) 6.22
Phosphorylation of HuR by Chk2 regulates SIRT1 expression. Mol Cell (2007) 5.29
Identification and functional outcome of mRNAs associated with RNA-binding protein TIA-1. Mol Cell Biol (2005) 2.83
Antiapoptotic function of RNA-binding protein HuR effected through prothymosin alpha. EMBO J (2005) 2.33
The zinc-finger antiviral protein recruits the RNA processing exosome to degrade the target mRNA. Proc Natl Acad Sci U S A (2006) 2.12
Translational control of cytochrome c by RNA-binding proteins TIA-1 and HuR. Mol Cell Biol (2006) 2.05
Translational repression by RNA-binding protein TIAR. Mol Cell Biol (2006) 1.87
Inhibition of the ubiquitin-proteasome system induces stress granule formation. Mol Biol Cell (2007) 1.75
Involvement of KSRP in the post-transcriptional regulation of human iNOS expression-complex interplay of KSRP with TTP and HuR. Nucleic Acids Res (2005) 1.69
The herpes simplex virus 1 UL41 gene-dependent destabilization of cellular RNAs is selective and may be sequence-specific. Proc Natl Acad Sci U S A (2004) 1.62
Decoding ARE-mediated decay: is microRNA part of the equation? J Cell Biol (2008) 1.60
Point mutations and genomic deletions in CCND1 create stable truncated cyclin D1 mRNAs that are associated with increased proliferation rate and shorter survival. Blood (2007) 1.60
A new Arabidopsis gene, FLK, encodes an RNA binding protein with K homology motifs and regulates flowering time via FLOWERING LOCUS C. Plant Cell (2004) 1.56
Global analysis of Pub1p targets reveals a coordinate control of gene expression through modulation of binding and stability. Mol Cell Biol (2005) 1.50
Tethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decay. Mol Cell Biol (2006) 1.44
The RNA-binding zinc-finger protein tristetraprolin regulates AU-rich mRNAs involved in breast cancer-related processes. Oncogene (2010) 1.43
Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype. Oncogene (2008) 1.41
Multifaceted actions of 8-amino-adenosine kill BCR-ABL positive cells. Leuk Lymphoma (2012) 1.40
The new face of the old molecules: crustin Pm4 and transglutaminase type I serving as rnps down-regulate astakine-mediated hematopoiesis. PLoS One (2013) 1.40
miRNA regulation of cytokine genes. Cytokine (2009) 1.39
KLF4 and PCNA identify stages of tumor initiation in a conditional model of cutaneous squamous epithelial neoplasia. Cancer Biol Ther (2005) 1.38
The RNA-binding protein TbDRBD3 regulates the stability of a specific subset of mRNAs in trypanosomes. Nucleic Acids Res (2008) 1.32
Endotoxin mediates recruitment of RNA polymerase II to target genes in acute renal failure. J Am Soc Nephrol (2008) 1.23
Transcriptional regulation of long-term memory in the marine snail Aplysia. Mol Brain (2008) 1.23
p38alpha stabilizes interleukin-6 mRNA via multiple AU-rich elements. J Biol Chem (2007) 1.21
Roles of a Trypanosoma brucei 5'->3' exoribonuclease homolog in mRNA degradation. RNA (2006) 1.17
Convergent actions of I kappa B kinase beta and protein kinase C delta modulate mRNA stability through phosphorylation of 14-3-3 beta complexed with tristetraprolin. Mol Cell Biol (2005) 1.13
Posttranscriptional control of type I interferon genes by KSRP in the innate immune response against viral infection. Mol Cell Biol (2011) 1.13
p38 MAPK regulates IL-1beta induced IL-6 expression through mRNA stability in osteoblasts. Immunol Invest (2004) 1.12
L-arginine deprivation regulates cyclin D3 mRNA stability in human T cells by controlling HuR expression. J Immunol (2010) 1.06
AU-rich elements regulate Drosophila gene expression. Mol Cell Biol (2009) 1.05
Modulation of utrophin A mRNA stability in fast versus slow muscles via an AU-rich element and calcineurin signaling. Nucleic Acids Res (2007) 1.05
Resistance of human hepatitis delta virus RNAs to dicer activity. J Virol (2003) 1.04
Oncogenic Ras and transforming growth factor-beta synergistically regulate AU-rich element-containing mRNAs during epithelial to mesenchymal transition. Mol Cancer Res (2008) 1.04
QKI binds MAP1B mRNA and enhances MAP1B expression during oligodendrocyte development. Mol Biol Cell (2006) 1.03
IL-4-Stat6 signaling induces tristetraprolin expression and inhibits TNF-alpha production in mast cells. J Exp Med (2003) 1.03
Circadian amplitude of cryptochrome 1 is modulated by mRNA stability regulation via cytoplasmic hnRNP D oscillation. Mol Cell Biol (2010) 0.99
Cip1 and Cip2 are novel RNA-recognition-motif proteins that counteract Csx1 function during oxidative stress. Mol Biol Cell (2006) 0.98
A nonclassical arabinogalactan protein gene highly expressed in vascular tissues, AGP31, is transcriptionally repressed by methyl jasmonic acid in Arabidopsis. Plant Physiol (2007) 0.98
Intronic splicing of hyaluronan synthase 1 (HAS1): a biologically relevant indicator of poor outcome in multiple myeloma. Blood (2005) 0.97
Epidermal growth factor increases the interaction between nucleolin and heterogeneous nuclear ribonucleoprotein K/poly(C) binding protein 1 complex to regulate the gastrin mRNA turnover. Mol Biol Cell (2007) 0.97
JNK activation decreases PP2A regulatory subunit B56alpha expression and mRNA stability and increases AUF1 expression in cardiomyocytes. Am J Physiol Heart Circ Physiol (2006) 0.96
A common variant in the 3'UTR of the GRIK4 glutamate receptor gene affects transcript abundance and protects against bipolar disorder. Proc Natl Acad Sci U S A (2008) 0.96
HuR stabilizes vacuolar H+-translocating ATPase mRNA during cellular energy depletion. J Biol Chem (2005) 0.95
Temporally regulated traffic of HuR and its associated ARE-containing mRNAs from the chromatoid body to polysomes during mouse spermatogenesis. PLoS One (2009) 0.93
Selective translational repression of HIV-1 RNA by Sam68DeltaC occurs by altering PABP1 binding to unspliced viral RNA. Retrovirology (2008) 0.93
The 3' untranslated region of human Cyclin-Dependent Kinase 5 Regulatory subunit 1 contains regulatory elements affecting transcript stability. BMC Mol Biol (2007) 0.91
Spam1-associated transmission ratio distortion in mice: elucidating the mechanism. Reprod Biol Endocrinol (2005) 0.91
Improvement of reporter activity by IRES-mediated polycistronic reporter system. Nucleic Acids Res (2008) 0.90
Mutations and novel polymorphisms in coding regions and UTRs of CDK5R1 and OMG genes in patients with non-syndromic mental retardation. Neurogenetics (2006) 0.89
The RNA-binding protein ELAVL1/HuR is essential for mouse spermatogenesis, acting both at meiotic and postmeiotic stages. Mol Biol Cell (2011) 0.88
Posttranscriptional control of photosynthetic mRNA decay under stress conditions requires 3' and 5' untranslated regions and correlates with differential polysome association in rice. Plant Physiol (2012) 0.88
The DMD locus harbours multiple long non-coding RNAs which orchestrate and control transcription of muscle dystrophin mRNA isoforms. PLoS One (2012) 0.87
Variation in dermcidin expression in a range of primary human tumours and in hypoxic/oxidatively stressed human cell lines. Br J Cancer (2008) 0.87
PTHrP gene expression in cancer: do all paths lead to Ets? Crit Rev Eukaryot Gene Expr (2005) 0.86
The cAMP-responsive element binding protein (CREB) regulates the expression of acid ceramidase (ASAH1) in H295R human adrenocortical cells. Biochim Biophys Acta (2009) 0.86
Translating the Untranslated Region. J Immunol (2015) 0.86
AUF1 p42 isoform selectively controls both steady-state and PGE2-induced FGF9 mRNA decay. Nucleic Acids Res (2010) 0.85
Alternative splicing of parathyroid hormone-related protein mRNA: expression and stability. J Mol Endocrinol (2004) 0.85
Cytoplasmatic post-transcriptional regulation and intracellular signalling. Mol Genet Genomics (2007) 0.83
Differential regulation of mRNA stability controls the transient expression of genes encoding Drosophila antimicrobial peptide with distinct immune response characteristics. Nucleic Acids Res (2009) 0.82
B cell lymphoma (Bcl)-2 protein is the major determinant in bcl-2 adenine-uridine-rich element turnover overcoming HuR activity. J Biol Chem (2009) 0.82
Evolutionary conservation and functional roles of ncRNA. Front Genet (2012) 0.81
Role of KSRP in control of type I interferon and cytokine expression. J Interferon Cytokine Res (2014) 0.80
Downregulation of Nipah virus N mRNA occurs through interaction between its 3' untranslated region and hnRNP D. J Virol (2013) 0.80
zeta-Crystallin is a bcl-2 mRNA binding protein involved in bcl-2 overexpression in T-cell acute lymphocytic leukemia. FASEB J (2010) 0.79
Genome-wide assessment of post-transcriptional control in the fly brain. Front Mol Neurosci (2013) 0.79
KSRP is critical in governing hepatic lipid metabolism through controlling Per2 expression. J Lipid Res (2014) 0.79
Tristetraprolin Recruits the Herpes Simplex Virion Host Shutoff RNase to AU-Rich Elements in Stress Response mRNAs To Enable Their Cleavage. J Virol (2015) 0.79
Multilevel regulation of HIF-1 signaling by TTP. Mol Biol Cell (2012) 0.79
A potential proliferative gene, NUDT6, is down-regulated by green tea catechins at the posttranscriptional level. J Nutr Biochem (2009) 0.79
Enrichment of inflammatory bowel disease and colorectal cancer risk variants in colon expression quantitative trait loci. BMC Genomics (2015) 0.78
p85α promotes nucleolin transcription and subsequently enhances EGFR mRNA stability and EGF-induced malignant cellular transformation. Oncotarget (2016) 0.78
Pycnogenol Attenuates the Release of Proinflammatory Cytokines and Expression of Perilipin 2 in Lipopolysaccharide-Stimulated Microglia in Part via Inhibition of NF-κB and AP-1 Activation. PLoS One (2015) 0.78
mRNA decay proteins are targeted to poly(A)+ RNA and dsRNA-containing cytoplasmic foci that resemble P-bodies in Entamoeba histolytica. PLoS One (2012) 0.78
Optimization of translation profiles enhances protein expression and solubility. PLoS One (2015) 0.78
DEAD box protein DDX1 regulates cytoplasmic localization of KSRP. PLoS One (2013) 0.77
Recruitment, Duplex Unwinding and Protein-Mediated Inhibition of the Dead-Box RNA Helicase Dbp2 at Actively Transcribed Chromatin. J Mol Biol (2016) 0.77
Novel mRNA-containing cytoplasmic granules in ALK-transformed cells. Mol Biol Cell (2011) 0.77
AU-rich element-binding protein negatively regulates CCAAT enhancer-binding protein mRNA stability during long-term synaptic plasticity in Aplysia. Proc Natl Acad Sci U S A (2012) 0.77
Secondary structure of the Irf7 5'-UTR, analyzed using SHAPE (selective 2'-hydroxyl acylation analyzed by primer extension). BMB Rep (2014) 0.77
Variation among rainbow trout (Oncorhynchus mykiss) estrogen receptor isoform 3' untranslated regions and the effect of 17beta-estradiol on mRNA stability in hepatocyte culture. DNA Cell Biol (2010) 0.77
Thy-1 mRNA destabilization by norepinephrine a 3' UTR cAMP responsive decay element and involves RNA binding proteins. Brain Behav Immun (2010) 0.76
Replication error deficient and proficient colorectal cancer gene expression differences caused by 3'UTR polyT sequence deletions. Proc Natl Acad Sci U S A (2010) 0.76
SAMe and HuR in liver physiology: usefulness of stem cells in hepatic differentiation research. Methods Mol Biol (2012) 0.75
A glutamine-rich factor affects stem cell genesis in leech. Stem Cells Int (2010) 0.75
RrmA regulates the stability of specific transcripts in response to both nitrogen source and oxidative stress. Mol Microbiol (2013) 0.75
Natural compounds for cancer treatment and prevention. Pharmacol Res (2009) 2.07
mTOR: a protein kinase switching between life and death. Pharmacol Res (2004) 1.55
Ocular safety of infliximab in rabbit and cell culture models. J Ocul Pharmacol Ther (2010) 1.39
AUF1 Is a bcl-2 A + U-rich element-binding protein involved in bcl-2 mRNA destabilization during apoptosis. J Biol Chem (2002) 1.36
Coenzyme q10 prevents apoptosis by inhibiting mitochondrial depolarization independently of its free radical scavenging property. J Biol Chem (2003) 1.25
Bcl-2 phosphorylation and apoptosis activated by damaged microtubules require mTOR and are regulated by Akt. Oncogene (2004) 1.17
The role of cyclooxygenase-2 in mediating the effects of histamine on cell proliferation and vascular endothelial growth factor production in colorectal cancer. Clin Cancer Res (2005) 1.09
Preferential chemosensitization of PTEN-mutated prostate cells by silencing the Akt kinase. Prostate (2007) 1.08
Identification of TINO: a new evolutionarily conserved BCL-2 AU-rich element RNA-binding protein. J Biol Chem (2004) 1.08
Inhibition of 5-lipoxygenase by MK886 augments the antitumor activity of celecoxib in human colon cancer cells. Mol Cancer Ther (2006) 1.06
Cannabinoid receptor activation induces apoptosis through tumor necrosis factor alpha-mediated ceramide de novo synthesis in colon cancer cells. Clin Cancer Res (2008) 1.04
Synergic antiproliferative and antiangiogenic effects of EGFR and mTor inhibitors on pancreatic cancer cells. Biochem Pharmacol (2007) 1.03
Down-regulation of nitric oxide synthase-2 and cyclooxygenase-2 pathways by p53 in squamous cell carcinoma. Am J Pathol (2003) 1.01
LMW-PTP is a positive regulator of tumor onset and growth. Oncogene (2004) 1.00
MYC prevents apoptosis and enhances endoreduplication induced by paclitaxel. PLoS One (2009) 0.98
The 3' untranslated region of human Cyclin-Dependent Kinase 5 Regulatory subunit 1 contains regulatory elements affecting transcript stability. BMC Mol Biol (2007) 0.91
In vitro blockade of receptor activator of nuclear factor-kappaB ligand prevents osteoclastogenesis induced by neuroblastoma cells. Int J Cancer (2004) 0.91
B cell lymphoma (Bcl)-2 protein is the major determinant in bcl-2 adenine-uridine-rich element turnover overcoming HuR activity. J Biol Chem (2009) 0.82
Coenzyme Q10 protects retinal cells from apoptosis induced by radiation in vitro and in vivo. J Radiat Res (2012) 0.82
Apoptosis shifts to necrosis via intermediate types of cell death by a mechanism depending on c-myc and bcl-2 expression. Cell Tissue Res (2004) 0.81
Downregulation of bcl-2 expression in lymphoma cells by bcl-2 ARE-targeted modified, synthetic ribozyme. Cancer Gene Ther (2003) 0.81
Stabilization of cellular mRNAs and up-regulation of proteins by oligoribonucleotides homologous to the Bcl2 adenine-uridine rich element motif. Mol Pharmacol (2006) 0.81
Divergent pathways for TNF and C(2)-ceramide toxicity in HTC hepatoma cells. Biochim Biophys Acta (2009) 0.80
Anticancer activity of an antisense oligonucleotide targeting TRADD combined with proteasome inhibitors in chemoresistant hepatocellular carcinoma cells. J Chemother (2013) 0.80
Energy-dependent types of cell death in MCF-7 breast cancer cell tumors implanted into nude mice. Cells Tissues Organs (2002) 0.80
Coenzyme Q10 instilled as eye drops on the cornea reaches the retina and protects retinal layers from apoptosis in a mouse model of kainate-induced retinal damage. Invest Ophthalmol Vis Sci (2012) 0.80
Molecular characterization of established human colon carcinoma cell lines (HCT-8) made resistant to 5-fluorouracil by different selection schedules. Oncol Res (2005) 0.79
zeta-Crystallin is a bcl-2 mRNA binding protein involved in bcl-2 overexpression in T-cell acute lymphocytic leukemia. FASEB J (2010) 0.79
Phosphodiester oligonucleotides inhibit mitosis and trigger apoptosis by a non-antisense, p53-mediated mechanism. Antisense Nucleic Acid Drug Dev (2002) 0.78
Autologous lipofilling: coenzyme Q10 can rescue adipocytes from stress-induced apoptotic death. Plast Reconstr Surg (2007) 0.78
Increased Bcl2 expression by antisense oligoribonucleotides targeting the adenine-uridine-rich element motif. Mol Pharmacol (2005) 0.77
Concomitant effect of topical ubiquinone Q10 and vitamin E to prevent keratocyte apoptosis after excimer laser photoablation in rabbits. J Refract Surg (2002) 0.77
Bcl-2 protein is required for the adenine/uridine-rich element (ARE)-dependent degradation of its own messenger. J Biol Chem (2003) 0.77
Impact of targeting the adenine- and uracil-rich element of bcl-2 mRNA with oligoribonucleotides on apoptosis, cell cycle, and neuronal differentiation in SHSY-5Y cells. Mol Pharmacol (2007) 0.76
Lipolytic effectiveness of phosphatidylcholine in the treatment of 'buffalo hump' of HIV patients. J Plast Reconstr Aesthet Surg (2010) 0.75
RNA targeting in cancer cells. Suppl Tumori (2003) 0.75