John D Aitchison

Author PubWeight™ 87.80‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs. Mol Cell 2006 3.87
2 A data integration methodology for systems biology. Proc Natl Acad Sci U S A 2005 2.93
3 Virtual gating and nuclear transport: the hole picture. Trends Cell Biol 2003 2.68
4 Comprehensive analysis of diverse ribonucleoprotein complexes. Nat Methods 2007 2.55
5 Transcriptome profiling to identify genes involved in peroxisome assembly and function. J Cell Biol 2002 2.30
6 Cell cycle regulated transport controlled by alterations in the nuclear pore complex. Cell 2003 2.27
7 Proteomic and genomic characterization of chromatin complexes at a boundary. J Cell Biol 2005 1.92
8 Approaching complete peroxisome characterization by gas-phase fractionation. Electrophoresis 2002 1.78
9 A data integration methodology for systems biology: experimental verification. Proc Natl Acad Sci U S A 2005 1.77
10 Dual feedback loops in the GAL regulon suppress cellular heterogeneity in yeast. Nat Genet 2006 1.70
11 The mobile nucleoporin Nup2p and chromatin-bound Prp20p function in endogenous NPC-mediated transcriptional control. J Cell Biol 2005 1.59
12 Peroxisomes take shape. Nat Rev Mol Cell Biol 2013 1.59
13 The peroxisomal membrane protein Inp2p is the peroxisome-specific receptor for the myosin V motor Myo2p of Saccharomyces cerevisiae. Dev Cell 2006 1.46
14 GINS motion reveals replication fork progression is remarkably uniform throughout the yeast genome. Mol Syst Biol 2010 1.45
15 A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses. Nature 2012 1.44
16 Quantitative mass spectrometry reveals a role for the GTPase Rho1p in actin organization on the peroxisome membrane. J Cell Biol 2004 1.38
17 Interactions between Mad1p and the nuclear transport machinery in the yeast Saccharomyces cerevisiae. Mol Biol Cell 2005 1.34
18 Transcriptional responses to fatty acid are coordinated by combinatorial control. Mol Syst Biol 2007 1.33
19 Systems biology at the Institute for Systems Biology. Brief Funct Genomic Proteomic 2008 1.30
20 Inp1p is a peroxisomal membrane protein required for peroxisome inheritance in Saccharomyces cerevisiae. J Cell Biol 2005 1.29
21 Karyopherins in nuclear pore biogenesis: a role for Kap121p in the assembly of Nup53p into nuclear pore complexes. J Cell Biol 2002 1.29
22 The role of karyopherins in the regulated sumoylation of septins. J Cell Biol 2007 1.22
23 Role of the histone variant H2A.Z/Htz1p in TBP recruitment, chromatin dynamics, and regulated expression of oleate-responsive genes. Mol Cell Biol 2009 1.19
24 Characterization of karyopherin cargoes reveals unique mechanisms of Kap121p-mediated nuclear import. Mol Cell Biol 2004 1.18
25 Expression and functional profiling reveal distinct gene classes involved in fatty acid metabolism. Mol Syst Biol 2006 1.16
26 Genome-wide analysis of signaling networks regulating fatty acid-induced gene expression and organelle biogenesis. J Cell Biol 2008 1.14
27 Pex11-related proteins in peroxisome dynamics: a role for the novel peroxin Pex27p in controlling peroxisome size and number in Saccharomyces cerevisiae. Mol Biol Cell 2003 1.14
28 Pex30p, Pex31p, and Pex32p form a family of peroxisomal integral membrane proteins regulating peroxisome size and number in Saccharomyces cerevisiae. Mol Biol Cell 2003 1.12
29 NUP-1 Is a large coiled-coil nucleoskeletal protein in trypanosomes with lamin-like functions. PLoS Biol 2012 1.12
30 A role for the nucleoporin Nup170p in chromatin structure and gene silencing. Cell 2013 1.12
31 Faster, quantitative, and accurate precursor acquisition independent from ion count. Anal Chem 2011 1.11
32 Kap121p-mediated nuclear import is required for mating and cellular differentiation in yeast. Mol Cell Biol 2002 1.11
33 Saccharomyces cerevisiae Yta7 regulates histone gene expression. Genetics 2008 1.09
34 Control of transcriptional variability by overlapping feed-forward regulatory motifs. Biophys J 2008 1.08
35 Myosin-driven peroxisome partitioning in S. cerevisiae. J Cell Biol 2009 1.08
36 Role of the nuclear envelope in genome organization and gene expression. Wiley Interdiscip Rev Syst Biol Med 2011 1.04
37 YHR150w and YDR479c encode peroxisomal integral membrane proteins involved in the regulation of peroxisome number, size, and distribution in Saccharomyces cerevisiae. J Cell Biol 2003 1.04
38 Dynamic changes in the subcellular distribution of Gpd1p in response to cell stress. J Biol Chem 2009 1.04
39 A noncanonical bromodomain in the AAA ATPase protein Yta7 directs chromosomal positioning and barrier chromatin activity. Mol Cell Biol 2009 1.00
40 Deterministic and stochastic models of genetic regulatory networks. Methods Enzymol 2009 0.98
41 Regulation of peroxisome dynamics. Curr Opin Cell Biol 2009 0.98
42 Utp8p is an essential intranuclear component of the nuclear tRNA export machinery of Saccharomyces cerevisiae. J Biol Chem 2003 0.95
43 Nanospray FAIMS fractionation provides significant increases in proteome coverage of unfractionated complex protein digests. Mol Cell Proteomics 2011 0.92
44 The dynamin-like protein Vps1p of the yeast Saccharomyces cerevisiae associates with peroxisomes in a Pex19p-dependent manner. J Biol Chem 2006 0.92
45 A regression model approach to enable cell morphology correction in high-throughput flow cytometry. Mol Syst Biol 2011 0.90
46 Multifunctional double-negative T cells in sooty mangabeys mediate T-helper functions irrespective of SIV infection. PLoS Pathog 2013 0.89
47 Global analysis of condition-specific subcellular protein distribution and abundance. Mol Cell Proteomics 2013 0.89
48 Nop53p is a novel nucleolar 60S ribosomal subunit biogenesis protein. Biochem J 2005 0.88
49 Integrated phosphoproteomics analysis of a signaling network governing nutrient response and peroxisome induction. Mol Cell Proteomics 2010 0.88
50 Studying nuclear protein import in yeast. Methods 2006 0.87
51 Asymmetric positive feedback loops reliably control biological responses. Mol Syst Biol 2012 0.86
52 Environment-responsive transcription factors bind subtelomeric elements and regulate gene silencing. Mol Syst Biol 2011 0.85
53 The peroxin Pex34p functions with the Pex11 family of peroxisomal divisional proteins to regulate the peroxisome population in yeast. Mol Biol Cell 2011 0.85
54 Trade-off between responsiveness and noise suppression in biomolecular system responses to environmental cues. PLoS Comput Biol 2011 0.85
55 Pex19p binds Pex30p and Pex32p at regions required for their peroxisomal localization but separate from their peroxisomal targeting signals. J Biol Chem 2006 0.85
56 Molecular mechanisms of system responses to novel stimuli are predictable from public data. Nucleic Acids Res 2013 0.85
57 Genome-wide analysis of effectors of peroxisome biogenesis. PLoS One 2010 0.85
58 Histone chaperone Chz1p regulates H2B ubiquitination and subtelomeric anti-silencing. Nucleic Acids Res 2009 0.84
59 QTIPS: a novel method of unsupervised determination of isotopic amino acid distribution in SILAC experiments. J Am Soc Mass Spectrom 2010 0.83
60 Nuclear pore complex evolution: a trypanosome Mlp analogue functions in chromosomal segregation but lacks transcriptional barrier activity. Mol Biol Cell 2014 0.83
61 Systematic measurement of transcription factor-DNA interactions by targeted mass spectrometry identifies candidate gene regulatory proteins. Proc Natl Acad Sci U S A 2013 0.83
62 A role for the karyopherin Kap123p in microtubule stability. Traffic 2009 0.82
63 Corrigendum: Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity. Nature 2015 0.81
64 Metallochaperones regulate intracellular copper levels. PLoS Comput Biol 2013 0.81
65 An evolutionarily conserved RNase-based mechanism for repression of transcriptional positive autoregulation. Mol Microbiol 2014 0.80
66 Identifying bona fide components of an organelle by isotope-coded labeling of subcellular fractions : an example in peroxisomes. Methods Mol Biol 2008 0.77
67 Cell biology: pore puzzle. Nature 2007 0.77
68 PhosphoChain: a novel algorithm to predict kinase and phosphatase networks from high-throughput expression data. Bioinformatics 2013 0.77
69 Expression of the Salmonella spp. virulence factor SifA in yeast alters Rho1 activity on peroxisomes. Mol Biol Cell 2010 0.76
70 Quantitative phosphoproteomics in fatty acid stimulated Saccharomyces cerevisiae. J Vis Exp 2009 0.76
71 Statistical analysis of dynamic transcriptional regulatory network structure. Methods Mol Biol 2011 0.76
72 Mathematical modeling of biomolecular network dynamics. Methods Mol Biol 2011 0.76
73 Bicluster Sampled Coherence Metric (BSCM) provides an accurate environmental context for phenotype predictions. BMC Syst Biol 2015 0.75
74 Systems cell biology of the mitotic spindle. J Cell Biol 2010 0.75