Published in J Cell Biol on August 17, 2009
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Direct interaction between a myosin V motor and the Rab GTPases Ypt31/32 is required for polarized secretion. Mol Biol Cell (2008) 1.45
Regulated degradation of a class V myosin receptor directs movement of the yeast vacuole. Nature (2003) 1.45
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Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair. Cell (2009) 2.90
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RAD18 transmits DNA damage signalling to elicit homologous recombination repair. Nat Cell Biol (2009) 2.67
Cargo-selected transport from the mitochondria to peroxisomes is mediated by vesicular carriers. Curr Biol (2008) 2.67
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PI(3,5)P(2) controls membrane trafficking by direct activation of mucolipin Ca(2+) release channels in the endolysosome. Nat Commun (2010) 2.54
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Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p. J Cell Biol (2002) 2.52
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Transcriptome profiling to identify genes involved in peroxisome assembly and function. J Cell Biol (2002) 2.30
Cell cycle regulated transport controlled by alterations in the nuclear pore complex. Cell (2003) 2.27
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The molecular architecture of the mammalian DNA repair enzyme, polynucleotide kinase. Mol Cell (2005) 2.09
VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse. EMBO J (2008) 2.08
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Batf coordinates multiple aspects of B and T cell function required for normal antibody responses. J Exp Med (2010) 1.92
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The Vac14p-Fig4p complex acts independently of Vac7p and couples PI3,5P2 synthesis and turnover. J Cell Biol (2006) 1.86
Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member. Mol Biol Cell (2002) 1.84
Yeast homotypic vacuole fusion requires the Ccz1-Mon1 complex during the tethering/docking stage. J Cell Biol (2003) 1.81
Approaching complete peroxisome characterization by gas-phase fractionation. Electrophoresis (2002) 1.78
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ATR autophosphorylation as a molecular switch for checkpoint activation. Mol Cell (2011) 1.70
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Phosphoinositide 5-phosphatase Fig 4p is required for both acute rise and subsequent fall in stress-induced phosphatidylinositol 3,5-bisphosphate levels. Eukaryot Cell (2006) 1.69
BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control. Mol Cell (2010) 1.65
Pex3p initiates the formation of a preperoxisomal compartment from a subdomain of the endoplasmic reticulum in Saccharomyces cerevisiae. J Biol Chem (2005) 1.62
Comprehensive analysis of missense variations in the BRCT domain of BRCA1 by structural and functional assays. Cancer Res (2010) 1.62
Detection of protein folding defects caused by BRCA1-BRCT truncation and missense mutations. J Biol Chem (2003) 1.61
The mobile nucleoporin Nup2p and chromatin-bound Prp20p function in endogenous NPC-mediated transcriptional control. J Cell Biol (2005) 1.59
Peroxisomes take shape. Nat Rev Mol Cell Biol (2013) 1.59
Identification of an organelle-specific myosin V receptor. J Cell Biol (2003) 1.57
Myosin V transports secretory vesicles via a Rab GTPase cascade and interaction with the exocyst complex. Dev Cell (2011) 1.50
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Problems with co-funding in Canada. Science (2005) 1.48
Tidying up loose ends: the role of polynucleotide kinase/phosphatase in DNA strand break repair. Trends Biochem Sci (2011) 1.47
The peroxisomal membrane protein Inp2p is the peroxisome-specific receptor for the myosin V motor Myo2p of Saccharomyces cerevisiae. Dev Cell (2006) 1.46
Direct interaction between a myosin V motor and the Rab GTPases Ypt31/32 is required for polarized secretion. Mol Biol Cell (2008) 1.45
GINS motion reveals replication fork progression is remarkably uniform throughout the yeast genome. Mol Syst Biol (2010) 1.45
Regulated degradation of a class V myosin receptor directs movement of the yeast vacuole. Nature (2003) 1.45
A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses. Nature (2012) 1.44
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In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P. Proc Natl Acad Sci U S A (2012) 1.39
Quantitative mass spectrometry reveals a role for the GTPase Rho1p in actin organization on the peroxisome membrane. J Cell Biol (2004) 1.38
A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis. Dev Cell (2013) 1.36
Interactions between Mad1p and the nuclear transport machinery in the yeast Saccharomyces cerevisiae. Mol Biol Cell (2005) 1.34
Transcriptional responses to fatty acid are coordinated by combinatorial control. Mol Syst Biol (2007) 1.33
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Karyopherins in nuclear pore biogenesis: a role for Kap121p in the assembly of Nup53p into nuclear pore complexes. J Cell Biol (2002) 1.29
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Orchestrating organelle inheritance in Saccharomyces cerevisiae. Curr Opin Microbiol (2007) 1.23
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The role of karyopherins in the regulated sumoylation of septins. J Cell Biol (2007) 1.22
Comparison of the structures and peptide binding specificities of the BRCT domains of MDC1 and BRCA1. Structure (2010) 1.21
Crystal structure of a core spliceosomal protein interface. Proc Natl Acad Sci U S A (2006) 1.20
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A new definition for the consensus sequence of the peroxisome targeting signal type 2. J Mol Biol (2004) 1.19
Role of the histone variant H2A.Z/Htz1p in TBP recruitment, chromatin dynamics, and regulated expression of oleate-responsive genes. Mol Cell Biol (2009) 1.19
Characterization of karyopherin cargoes reveals unique mechanisms of Kap121p-mediated nuclear import. Mol Cell Biol (2004) 1.18
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Dysferlin domain-containing proteins, Pex30p and Pex31p, localized to two compartments, control the number and size of oleate-induced peroxisomes in Pichia pastoris. Mol Biol Cell (2007) 1.16
Expression and functional profiling reveal distinct gene classes involved in fatty acid metabolism. Mol Syst Biol (2006) 1.16
Overlap of cargo binding sites on myosin V coordinates the inheritance of diverse cargoes. J Cell Biol (2012) 1.16
An ER-peroxisome tether exerts peroxisome population control in yeast. EMBO J (2013) 1.15
Dimerization of CtIP, a BRCA1- and CtBP-interacting protein, is mediated by an N-terminal coiled-coil motif. J Biol Chem (2004) 1.15
Genome-wide analysis of signaling networks regulating fatty acid-induced gene expression and organelle biogenesis. J Cell Biol (2008) 1.14
Pex11-related proteins in peroxisome dynamics: a role for the novel peroxin Pex27p in controlling peroxisome size and number in Saccharomyces cerevisiae. Mol Biol Cell (2003) 1.14
The peroxisome: orchestrating important developmental decisions from inside the cell. J Cell Biol (2004) 1.13
FinO is an RNA chaperone that facilitates sense-antisense RNA interactions. EMBO J (2003) 1.13
NUP-1 Is a large coiled-coil nucleoskeletal protein in trypanosomes with lamin-like functions. PLoS Biol (2012) 1.12
Pex30p, Pex31p, and Pex32p form a family of peroxisomal integral membrane proteins regulating peroxisome size and number in Saccharomyces cerevisiae. Mol Biol Cell (2003) 1.12
A role for the nucleoporin Nup170p in chromatin structure and gene silencing. Cell (2013) 1.12
BRCA1 DNA-binding activity is stimulated by BARD1. Cancer Res (2006) 1.12
Identification of an N-domain histidine essential for chaperone function in calreticulin. J Biol Chem (2003) 1.12