PubRank

Frank O Nestle

Author PubWeight™ 112.51‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide. Nature 2007 8.88
2 A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet 2010 8.48
3 Mapping cis- and trans-regulatory effects across multiple tissues in twins. Nat Genet 2012 6.97
4 The architecture of gene regulatory variation across multiple human tissues: the MuTHER study. PLoS Genet 2011 5.95
5 Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nat Genet 2012 4.13
6 The IL-23/Th17 axis in the immunopathogenesis of psoriasis. J Invest Dermatol 2009 3.93
7 Infliximab induction and maintenance therapy for moderate-to-severe psoriasis: a phase III, multicentre, double-blind trial. Lancet 2005 3.59
8 Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis. Hum Genet 2007 2.78
9 Alpha1beta1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis. Nat Med 2007 2.70
10 Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha. J Exp Med 2004 2.63
11 Psoriasis and systemic inflammatory diseases: potential mechanistic links between skin disease and co-morbid conditions. J Invest Dermatol 2010 2.46
12 Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene. Hum Mol Genet 2008 2.42
13 Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities. J Clin Invest 2004 2.34
14 Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis. Am J Hum Genet 2011 2.21
15 Psoriasis. Annu Rev Pathol 2011 2.21
16 Expression of CXC chemokine receptor-4 enhances the pulmonary metastatic potential of murine B16 melanoma cells. Cancer Res 2002 2.06
17 Psoriasis triggered by toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors. Arch Dermatol 2004 1.96
18 Resident CD141 (BDCA3)+ dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation. J Exp Med 2012 1.81
19 Identification of a novel proinflammatory human skin-homing Vγ9Vδ2 T cell subset with a potential role in psoriasis. J Immunol 2011 1.79
20 The IL23R R381Q gene variant protects against immune-mediated diseases by impairing IL-23-induced Th17 effector response in humans. PLoS One 2011 1.71
21 A model for harmonizing flow cytometry in clinical trials. Nat Immunol 2010 1.70
22 Cutting edge: A critical functional role for IL-23 in psoriasis. J Immunol 2010 1.61
23 Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells. Sci Transl Med 2011 1.56
24 Immunopathogenesis of psoriasis. Clin Rev Allergy Immunol 2007 1.46
25 The multitasking organ: recent insights into skin immune function. Immunity 2011 1.38
26 Immune evasion by murine melanoma mediated through CC chemokine receptor-10. J Exp Med 2003 1.34
27 Gene expression changes with age in skin, adipose tissue, blood and brain. Genome Biol 2013 1.34
28 The cytokine and chemokine network in psoriasis. Clin Dermatol 2007 1.31
29 Unraveling the autoimmune translational research process layer by layer. Nat Med 2012 1.27
30 The pathogenic role of tissue-resident immune cells in psoriasis. Trends Immunol 2007 1.27
31 TLRs to cytokines: mechanistic insights from the imiquimod mouse model of psoriasis. Eur J Immunol 2013 1.20
32 Metastatic melanoma secreted IL-10 down-regulates CD1 molecules on dendritic cells in metastatic tumor lesions. Am J Pathol 2004 1.16
33 IgG4 subclass antibodies impair antitumor immunity in melanoma. J Clin Invest 2013 1.12
34 Baseline nail disease in patients with moderate to severe psoriasis and response to treatment with infliximab during 1 year. J Am Acad Dermatol 2007 1.10
35 A systems model for immune cell interactions unravels the mechanism of inflammation in human skin. PLoS Comput Biol 2010 1.07
36 Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis. Hum Mol Genet 2012 1.06
37 Vaccination of patients with cutaneous T-cell lymphoma using intranodal injection of autologous tumor-lysate-pulsed dendritic cells. Blood 2003 1.05
38 Xenogeneic graft-versus-host-disease in NOD-scid IL-2Rγnull mice display a T-effector memory phenotype. PLoS One 2012 1.04
39 Recombinant IgE antibodies for passive immunotherapy of solid tumours: from concept towards clinical application. Cancer Immunol Immunother 2011 1.03
40 Characterisation of an engineered trastuzumab IgE antibody and effector cell mechanisms targeting HER2/neu-positive tumour cells. Cancer Immunol Immunother 2008 0.99
41 A role for Th17 cells in the immunopathogenesis of atopic dermatitis? J Invest Dermatol 2008 0.99
42 Intranodal injection of semimature monocyte-derived dendritic cells induces T helper type 1 responses to protein neoantigen. Blood 2003 0.96
43 Biomarkers in psoriasis and psoriatic arthritis. Ann Rheum Dis 2013 0.95
44 The IL23R A/Gln381 allele promotes IL-23 unresponsiveness in human memory T-helper 17 cells and impairs Th17 responses in psoriasis patients. J Invest Dermatol 2013 0.95
45 High frequency of melanoma-associated antigen or HLA class I loss does not correlate with survival in primary melanoma. J Immunother 2003 0.94
46 Functional expression of the eotaxin receptor CCR3 in CD30+ cutaneous T-cell lymphoma. Blood 2002 0.93
47 Monitoring the systemic human memory B cell compartment of melanoma patients for anti-tumor IgG antibodies. PLoS One 2011 0.92
48 The role of IL-23 in the immunopathogenesis of psoriasis. F1000 Biol Rep 2010 0.92
49 Integration of lyoplate based flow cytometry and computational analysis for standardized immunological biomarker discovery. PLoS One 2013 0.91
50 Integrative biology approach identifies cytokine targeting strategies for psoriasis. Sci Transl Med 2014 0.89
51 Nephrogenic fibrosing dermopathy treated with extracorporeal photopheresis. Dermatology 2004 0.88
52 Antibody-antigen-adjuvant conjugates enable co-delivery of antigen and adjuvant to dendritic cells in cis but only have partial targeting specificity. PLoS One 2012 0.87
53 Transcriptome classification reveals molecular subtypes in psoriasis. BMC Genomics 2012 0.87
54 An in-depth characterization of the major psoriasis susceptibility locus identifies candidate susceptibility alleles within an HLA-C enhancer element. PLoS One 2013 0.86
55 Harnessing dendritic cells in inflammatory skin diseases. Semin Immunol 2011 0.86
56 Allele-specific cytokine responses at the HLA-C locus: implications for psoriasis. J Invest Dermatol 2011 0.83
57 IgG4 antibodies and cancer-associated inflammation: Insights into a novel mechanism of immune escape. Oncoimmunology 2013 0.83
58 Animal models of psoriasis and psoriatic arthritis: an update. Curr Rheumatol Rep 2006 0.80
59 Toward prediction of immune mechanisms and design of immunotherapies in melanoma. Crit Rev Biomed Eng 2012 0.79
60 Infliximab treatment improves productivity among patients with moderate-to-severe psoriasis. Eur J Dermatol 2007 0.77
61 Advances in the treatment of melanoma. Clin Med 2012 0.77
62 What on "irf" is this gene 4? Irf4 transcription-factor-dependent dendritic cells are required for T helper 2 cell responses in murine skin. Immunity 2013 0.75
63 A new lease on life for dendritic cell vaccines? Nat Biotechnol 2006 0.75
64 Dendritic cell-based cancer therapy. Curr Opin Mol Ther 2003 0.75
65 Functional detection of epithelial cell adhesion molecule specific cytotoxic T lymphocytes in patients with lung cancer, colorectal cancer and in healthy donors. Lung Cancer 2002 0.75
66 Pathogenesis and immunotherapy in cutaneous psoriasis: what can rheumatologists learn? Curr Opin Rheumatol 2017 0.75
67 Antigen specific immunotherapy: Quo vadis? Swiss Med Wkly 2005 0.75
68 Real-time polymerase chain reaction monitoring of epithelial cell adhesion molecule-induced T-cell stimulation in patients with lung cancer and healthy individuals using LightCycler technology. J Immunother 2002 0.75
69 Painless erythema of the hands associated with non-Hodgkin's lymphoma in a lung transplant recipient. J Am Acad Dermatol 2002 0.75
70 From inflammation to neoplasia: new concepts in the pathogenesis of cutaneous lymphomas. Recent Results Cancer Res 2002 0.75