Characterization of a novel coronavirus associated with severe acute respiratory syndrome.

PubWeight™: 18.34‹?› | Rank: Top 0.1% | All-Time Top 10000

🔗 View Article (PMID 12730500)

Published in Science on May 01, 2003

Authors

Paul A Rota1, M Steven Oberste, Stephan S Monroe, W Allan Nix, Ray Campagnoli, Joseph P Icenogle, Silvia Peñaranda, Bettina Bankamp, Kaija Maher, Min-Hsin Chen, Suxiong Tong, Azaibi Tamin, Luis Lowe, Michael Frace, Joseph L DeRisi, Qi Chen, David Wang, Dean D Erdman, Teresa C T Peret, Cara Burns, Thomas G Ksiazek, Pierre E Rollin, Anthony Sanchez, Stephanie Liffick, Brian Holloway, Josef Limor, Karen McCaustland, Melissa Olsen-Rasmussen, Ron Fouchier, Stephan Günther, Albert D M E Osterhaus, Christian Drosten, Mark A Pallansch, Larry J Anderson, William J Bellini

Author Affiliations

1: National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. prota@cdc.gov

Articles citing this

(truncated to the top 100)

Hospital outbreak of Middle East respiratory syndrome coronavirus. N Engl J Med (2013) 11.85

Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia. J Virol (2005) 9.13

Bats: important reservoir hosts of emerging viruses. Clin Microbiol Rev (2006) 8.77

Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans. MBio (2012) 8.54

Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats. Proc Natl Acad Sci U S A (2005) 8.52

Discovery of seven novel Mammalian and avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses as the gene source of gammacoronavirus and deltacoronavirus. J Virol (2012) 6.04

Viral discovery and sequence recovery using DNA microarrays. PLoS Biol (2003) 5.95

A previously undescribed coronavirus associated with respiratory disease in humans. Proc Natl Acad Sci U S A (2004) 5.76

Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry. Proc Natl Acad Sci U S A (2005) 4.07

Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human. Proc Natl Acad Sci U S A (2005) 3.37

Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association. Proc Natl Acad Sci U S A (2004) 3.23

Complete genome sequence of a Chinese virulent porcine epidemic diarrhea virus strain. J Virol (2011) 3.19

Coronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus. Microbiol Mol Biol Rev (2005) 3.18

Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2. EMBO J (2005) 3.14

Comparative analysis of twelve genomes of three novel group 2c and group 2d coronaviruses reveals unique group and subgroup features. J Virol (2006) 3.07

pH-dependent entry of severe acute respiratory syndrome coronavirus is mediated by the spike glycoprotein and enhanced by dendritic cell transfer through DC-SIGN. J Virol (2004) 3.04

Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry. Proc Natl Acad Sci U S A (2004) 3.03

The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor. Proc Natl Acad Sci U S A (2003) 3.02

Real-time reverse transcription-polymerase chain reaction assay for SARS-associated coronavirus. Emerg Infect Dis (2004) 2.88

Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus. Proc Natl Acad Sci U S A (2003) 2.82

Evaluation of reverse transcription-PCR assays for rapid diagnosis of severe acute respiratory syndrome associated with a novel coronavirus. J Clin Microbiol (2003) 2.77

A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice. PLoS Pathog (2007) 2.71

Severe acute respiratory syndrome coronavirus phylogeny: toward consensus. J Virol (2004) 2.61

Recombination, reservoirs, and the modular spike: mechanisms of coronavirus cross-species transmission. J Virol (2009) 2.60

Pseudoknots: RNA structures with diverse functions. PLoS Biol (2005) 2.60

Development and evaluation of a novel loop-mediated isothermal amplification method for rapid detection of severe acute respiratory syndrome coronavirus. J Clin Microbiol (2004) 2.45

Coronavirus HKU1 and other coronavirus infections in Hong Kong. J Clin Microbiol (2006) 2.44

Severe acute respiratory syndrome coronavirus spike protein expressed by attenuated vaccinia virus protectively immunizes mice. Proc Natl Acad Sci U S A (2004) 2.38

CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus. Proc Natl Acad Sci U S A (2004) 2.38

Identification and characterization of severe acute respiratory syndrome coronavirus replicase proteins. J Virol (2004) 2.38

Multiple enzymatic activities associated with severe acute respiratory syndrome coronavirus helicase. J Virol (2004) 2.29

A novel pancoronavirus RT-PCR assay: frequent detection of human coronavirus NL63 in children hospitalized with respiratory tract infections in Belgium. BMC Infect Dis (2005) 2.28

Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme. Proc Natl Acad Sci U S A (2006) 2.28

A novel picornavirus associated with gastroenteritis. J Virol (2009) 2.25

The spike protein of SARS-CoV--a target for vaccine and therapeutic development. Nat Rev Microbiol (2009) 2.23

Severe acute respiratory syndrome coronavirus group-specific open reading frames encode nonessential functions for replication in cell cultures and mice. J Virol (2005) 2.22

Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry. Proc Natl Acad Sci U S A (2005) 2.21

Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome. Clin Exp Immunol (2004) 2.21

Ultrastructure and origin of membrane vesicles associated with the severe acute respiratory syndrome coronavirus replication complex. J Virol (2006) 2.20

Venezuelan encephalitis emergence mediated by a phylogenetically predicted viral mutation. Proc Natl Acad Sci U S A (2006) 2.07

Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus. J Biol Chem (2007) 2.07

Comparative analysis of complete genome sequences of three avian coronaviruses reveals a novel group 3c coronavirus. J Virol (2008) 2.06

Severe acute respiratory syndrome coronavirus infection of human ciliated airway epithelia: role of ciliated cells in viral spread in the conducting airways of the lungs. J Virol (2005) 2.05

Epidemiologic clues to SARS origin in China. Emerg Infect Dis (2004) 2.03

A metagenomic analysis of pandemic influenza A (2009 H1N1) infection in patients from North America. PLoS One (2010) 1.99

Identification of severe acute respiratory syndrome coronavirus replicase products and characterization of papain-like protease activity. J Virol (2004) 1.97

E-Predict: a computational strategy for species identification based on observed DNA microarray hybridization patterns. Genome Biol (2005) 1.93

Molecular evolution analysis and geographic investigation of severe acute respiratory syndrome coronavirus-like virus in palm civets at an animal market and on farms. J Virol (2005) 1.93

Comparative analysis of 22 coronavirus HKU1 genomes reveals a novel genotype and evidence of natural recombination in coronavirus HKU1. J Virol (2006) 1.87

Characterization of the RNA components of a putative molecular switch in the 3' untranslated region of the murine coronavirus genome. J Virol (2004) 1.85

Protease-mediated enhancement of severe acute respiratory syndrome coronavirus infection. Proc Natl Acad Sci U S A (2005) 1.85

SARS coronavirus: a new challenge for prevention and therapy. J Clin Invest (2003) 1.80

S protein of severe acute respiratory syndrome-associated coronavirus mediates entry into hepatoma cell lines and is targeted by neutralizing antibodies in infected patients. J Virol (2004) 1.80

Amino acids 270 to 510 of the severe acute respiratory syndrome coronavirus spike protein are required for interaction with receptor. J Virol (2004) 1.79

Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines. PLoS Pathog (2007) 1.78

Detection of specific antibodies to severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein for serodiagnosis of SARS coronavirus pneumonia. J Clin Microbiol (2004) 1.78

Ultrastructural characterization of SARS coronavirus. Emerg Infect Dis (2004) 1.76

Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain. J Virol (2007) 1.75

Evasion of antibody neutralization in emerging severe acute respiratory syndrome coronaviruses. Proc Natl Acad Sci U S A (2005) 1.75

Design of wide-spectrum inhibitors targeting coronavirus main proteases. PLoS Biol (2005) 1.73

Basic concepts of microarrays and potential applications in clinical microbiology. Clin Microbiol Rev (2009) 1.70

Contributions of the structural proteins of severe acute respiratory syndrome coronavirus to protective immunity. Proc Natl Acad Sci U S A (2004) 1.69

Use of the DNA flow-thru chip, a three-dimensional biochip, for typing and subtyping of influenza viruses. J Clin Microbiol (2004) 1.69

The nucleoprotein is required for efficient coronavirus genome replication. J Virol (2004) 1.68

Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection. Clin Microbiol Rev (2007) 1.68

Three distinct suppressors of RNA silencing encoded by a 20-kb viral RNA genome. Proc Natl Acad Sci U S A (2004) 1.67

MAVS-mediated apoptosis and its inhibition by viral proteins. PLoS One (2009) 1.67

The severe acute respiratory syndrome coronavirus Nsp15 protein is an endoribonuclease that prefers manganese as a cofactor. J Virol (2004) 1.67

Characterization of severe acute respiratory syndrome coronavirus genomes in Taiwan: molecular epidemiology and genome evolution. Proc Natl Acad Sci U S A (2004) 1.66

Severe acute respiratory syndrome coronavirus 3a protein is a viral structural protein. J Virol (2005) 1.64

Coronavirus genomics and bioinformatics analysis. Viruses (2010) 1.63

Identification of a severe acute respiratory syndrome coronavirus-like virus in a leaf-nosed bat in Nigeria. MBio (2010) 1.62

Cross-species transmission of a novel adenovirus associated with a fulminant pneumonia outbreak in a new world monkey colony. PLoS Pathog (2011) 1.62

Mosaic evolution of the severe acute respiratory syndrome coronavirus. J Virol (2004) 1.61

The severe acute respiratory syndrome-coronavirus replicative protein nsp9 is a single-stranded RNA-binding subunit unique in the RNA virus world. Proc Natl Acad Sci U S A (2004) 1.61

Expression profile of immune response genes in patients with Severe Acute Respiratory Syndrome. BMC Immunol (2005) 1.61

Molecular epidemiology of human coronavirus OC43 reveals evolution of different genotypes over time and recent emergence of a novel genotype due to natural recombination. J Virol (2011) 1.60

Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus. J Virol (2006) 1.59

Construction of a severe acute respiratory syndrome coronavirus infectious cDNA clone and a replicon to study coronavirus RNA synthesis. J Virol (2006) 1.57

Microbiologic characteristics, serologic responses, and clinical manifestations in severe acute respiratory syndrome, Taiwan. Emerg Infect Dis (2003) 1.55

Evaluation of human monoclonal antibody 80R for immunoprophylaxis of severe acute respiratory syndrome by an animal study, epitope mapping, and analysis of spike variants. J Virol (2005) 1.54

Coexistence of different genotypes in the same bat and serological characterization of Rousettus bat coronavirus HKU9 belonging to a novel Betacoronavirus subgroup. J Virol (2010) 1.53

A novel severe acute respiratory syndrome coronavirus protein, U274, is transported to the cell surface and undergoes endocytosis. J Virol (2004) 1.53

Chemokine up-regulation in SARS-coronavirus-infected, monocyte-derived human dendritic cells. Blood (2005) 1.52

Mechanisms of zoonotic severe acute respiratory syndrome coronavirus host range expansion in human airway epithelium. J Virol (2007) 1.52

A severe acute respiratory syndrome coronavirus that lacks the E gene is attenuated in vitro and in vivo. J Virol (2006) 1.51

Species-independent detection of RNA virus by representational difference analysis using non-ribosomal hexanucleotides for reverse transcription. Nucleic Acids Res (2005) 1.51

Interpretation of diagnostic laboratory tests for severe acute respiratory syndrome: the Toronto experience. CMAJ (2004) 1.50

MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV. PLoS Pathog (2008) 1.47

Isolation and characterization of current human coronavirus strains in primary human epithelial cell cultures reveal differences in target cell tropism. J Virol (2013) 1.47

SARS coronavirus and innate immunity. Virus Res (2007) 1.44

Chloroquine is a potent inhibitor of SARS coronavirus infection and spread. Virol J (2005) 1.43

Viral proteomics. Microbiol Mol Biol Rev (2007) 1.43

Analysis of intraviral protein-protein interactions of the SARS coronavirus ORFeome. PLoS One (2007) 1.42

In vitro reconstitution of SARS-coronavirus mRNA cap methylation. PLoS Pathog (2010) 1.41

Discovery of novel human and animal cells infected by the severe acute respiratory syndrome coronavirus by replication-specific multiplex reverse transcription-PCR. J Clin Microbiol (2004) 1.41

Middle East respiratory syndrome coronavirus accessory protein 4a is a type I interferon antagonist. J Virol (2013) 1.40

Evaluation of advanced reverse transcription-PCR assays and an alternative PCR target region for detection of severe acute respiratory syndrome-associated coronavirus. J Clin Microbiol (2004) 1.40

Evidence of the recombinant origin of a bat severe acute respiratory syndrome (SARS)-like coronavirus and its implications on the direct ancestor of SARS coronavirus. J Virol (2007) 1.39

A SARS DNA vaccine induces neutralizing antibody and cellular immune responses in healthy adults in a Phase I clinical trial. Vaccine (2008) 1.39

Articles by these authors

Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA (2003) 31.71

A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med (2003) 29.55

Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med (2003) 27.97

Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med (2012) 22.75

Emergence of Zaire Ebola virus disease in Guinea. N Engl J Med (2014) 16.45

Mapping the antigenic and genetic evolution of influenza virus. Science (2004) 14.28

Global patterns of influenza a virus in wild birds. Science (2006) 13.80

Airborne transmission of influenza A/H5N1 virus between ferrets. Science (2012) 13.48

Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise. Nature (2006) 12.92

Avian influenza A virus (H7N7) associated with human conjunctivitis and a fatal case of acute respiratory distress syndrome. Proc Natl Acad Sci U S A (2004) 12.39

The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum. PLoS Biol (2003) 11.86

Characterization of a novel influenza A virus hemagglutinin subtype (H16) obtained from black-headed gulls. J Virol (2005) 10.77

Retracted Identification of a novel Gammaretrovirus in prostate tumors of patients homozygous for R462Q RNASEL variant. PLoS Pathog (2006) 10.08

The global circulation of seasonal influenza A (H3N2) viruses. Science (2008) 10.05

Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. N Engl J Med (2013) 8.76

Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans. MBio (2012) 8.54

Assemblathon 1: a competitive assessment of de novo short read assembly methods. Genome Res (2011) 8.38

Identification of a novel polyomavirus from patients with acute respiratory tract infections. PLoS Pathog (2007) 8.01

Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study. Lancet Infect Dis (2013) 7.83

Pathogenesis and transmission of swine-origin 2009 A(H1N1) influenza virus in ferrets. Science (2009) 7.80

Norovirus classification and proposed strain nomenclature. Virology (2005) 7.69

Sensitive, seminested PCR amplification of VP1 sequences for direct identification of all enterovirus serotypes from original clinical specimens. J Clin Microbiol (2006) 7.56

Transmission of H7N7 avian influenza A virus to human beings during a large outbreak in commercial poultry farms in the Netherlands. Lancet (2004) 7.52

Aetiology: Koch's postulates fulfilled for SARS virus. Nature (2003) 7.51

The severe acute respiratory syndrome. N Engl J Med (2003) 7.48

Microarray-based detection and genotyping of viral pathogens. Proc Natl Acad Sci U S A (2002) 7.27

Rapid detection and quantification of RNA of Ebola and Marburg viruses, Lassa virus, Crimean-Congo hemorrhagic fever virus, Rift Valley fever virus, dengue virus, and yellow fever virus by real-time reverse transcription-PCR. J Clin Microbiol (2002) 6.60

Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome. Lancet (2003) 6.52

Assessment of the risk of Ebola virus transmission from bodily fluids and fomites. J Infect Dis (2007) 6.46

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC. Nature (2013) 6.39

A distinct lineage of influenza A virus from bats. Proc Natl Acad Sci U S A (2012) 6.27

Virological features and clinical manifestations associated with human metapneumovirus: a new paramyxovirus responsible for acute respiratory-tract infections in all age groups. J Infect Dis (2002) 6.09

Newly discovered ebola virus associated with hemorrhagic fever outbreak in Uganda. PLoS Pathog (2008) 6.07

Spatial, temporal, and species variation in prevalence of influenza A viruses in wild migratory birds. PLoS Pathog (2007) 6.04

Viral discovery and sequence recovery using DNA microarrays. PLoS Biol (2003) 5.95

Rapid diagnosis of Ebola hemorrhagic fever by reverse transcription-PCR in an outbreak setting and assessment of patient viral load as a predictor of outcome. J Virol (2004) 5.86

Trends in hospitalizations for pneumonia among persons aged 65 years or older in the United States, 1988-2002. JAMA (2005) 5.84

A previously undescribed coronavirus associated with respiratory disease in humans. Proc Natl Acad Sci U S A (2004) 5.76

Population-based surveillance for hospitalizations associated with respiratory syncytial virus, influenza virus, and parainfluenza viruses among young children. Pediatrics (2004) 5.74

Outbreak of poliomyelitis in Hispaniola associated with circulating type 1 vaccine-derived poliovirus. Science (2002) 5.71

Characterization of human metapneumoviruses isolated from patients in North America. J Infect Dis (2002) 5.64

Nipah virus encephalitis reemergence, Bangladesh. Emerg Infect Dis (2004) 5.49

Multiple Ebola virus transmission events and rapid decline of central African wildlife. Science (2004) 5.49

Transmission of lymphocytic choriomeningitis virus by organ transplantation. N Engl J Med (2006) 5.42

Avian H5N1 influenza in cats. Science (2004) 5.40

Clinical findings in 111 cases of influenza A (H7N9) virus infection. N Engl J Med (2013) 5.38

Human betacoronavirus 2c EMC/2012-related viruses in bats, Ghana and Europe. Emerg Infect Dis (2013) 5.25

Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group. J Virol (2013) 4.98

Human metapneumovirus infections in young and elderly adults. J Infect Dis (2003) 4.91

Epidemiologic and molecular trends of "Norwalk-like viruses" associated with outbreaks of gastroenteritis in the United States. J Infect Dis (2002) 4.88

Human and avian influenza viruses target different cells in the lower respiratory tract of humans and other mammals. Am J Pathol (2007) 4.86

Enterovirus surveillance--United States, 1970-2005. MMWR Surveill Summ (2006) 4.78

Analysis of the genomic sequence of a human metapneumovirus. Virology (2002) 4.64

Molecular predictors of outcome with gefitinib in a phase III placebo-controlled study in advanced non-small-cell lung cancer. J Clin Oncol (2006) 4.58

A case of severe Ebola virus infection complicated by gram-negative septicemia. N Engl J Med (2014) 4.57

Isolation of genetically diverse Marburg viruses from Egyptian fruit bats. PLoS Pathog (2009) 4.56

Evaluation and improvement of real-time PCR assays targeting lytA, ply, and psaA genes for detection of pneumococcal DNA. J Clin Microbiol (2007) 4.44

Vaccine-derived polioviruses and the endgame strategy for global polio eradication. Annu Rev Microbiol (2005) 4.42

Metagenomic analysis of human diarrhea: viral detection and discovery. PLoS Pathog (2008) 4.29

Expression profiling of the schizont and trophozoite stages of Plasmodium falciparum with a long-oligonucleotide microarray. Genome Biol (2003) 4.24

Severe respiratory illness associated with enterovirus D68 - Missouri and Illinois, 2014. MMWR Morb Mortal Wkly Rep (2014) 4.21

Pan-viral screening of respiratory tract infections in adults with and without asthma reveals unexpected human coronavirus and human rhinovirus diversity. J Infect Dis (2007) 4.16

A new phlebovirus associated with severe febrile illness in Missouri. N Engl J Med (2012) 4.15

Bats host major mammalian paramyxoviruses. Nat Commun (2012) 4.15

Transmission of rabies virus from an organ donor to four transplant recipients. N Engl J Med (2005) 4.05

Genome-wide mapping of the cohesin complex in the yeast Saccharomyces cerevisiae. PLoS Biol (2004) 4.03

Rift Valley fever epidemic in Saudi Arabia: epidemiological, clinical, and laboratory characteristics. Clin Infect Dis (2003) 4.02

Marburgvirus genomics and association with a large hemorrhagic fever outbreak in Angola. J Virol (2006) 4.01

Marburg virus infection detected in a common African bat. PLoS One (2007) 4.01

Clearance of influenza virus from the lung depends on migratory langerin+CD11b- but not plasmacytoid dendritic cells. J Exp Med (2008) 3.97

Human coronavirus EMC does not require the SARS-coronavirus receptor and maintains broad replicative capability in mammalian cell lines. MBio (2012) 3.96

Real-time reverse transcription-PCR assay for comprehensive detection of human rhinoviruses. J Clin Microbiol (2007) 3.95

Stroke and stroke care in China: huge burden, significant workload, and a national priority. Stroke (2011) 3.94

Genetic control of individual differences in gene-specific methylation in human brain. Am J Hum Genet (2010) 3.91

Virology: SARS virus infection of cats and ferrets. Nature (2003) 3.86