Published in Trends Cell Biol on May 01, 2003
MYC as a regulator of ribosome biogenesis and protein synthesis. Nat Rev Cancer (2010) 3.64
The nucleolus under stress. Mol Cell (2010) 3.63
Target of rapamycin (TOR) in nutrient signaling and growth control. Genetics (2011) 3.28
Gene and genon concept: coding versus regulation. A conceptual and information-theoretic analysis of genetic storage and expression in the light of modern molecular biology. Theory Biosci (2007) 2.89
Growth control of the eukaryote cell: a systems biology study in yeast. J Biol (2007) 2.79
RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components. Genes Dev (2004) 2.48
Prp43 bound at different sites on the pre-rRNA performs distinct functions in ribosome synthesis. Mol Cell (2009) 2.36
Release of the export adapter, Nmd3p, from the 60S ribosomal subunit requires Rpl10p and the cytoplasmic GTPase Lsg1p. EMBO J (2005) 2.22
The ribosomal basis of Diamond-Blackfan Anemia: mutation and database update. Hum Mutat (2010) 2.03
Maturation of eukaryotic ribosomes: acquisition of functionality. Trends Biochem Sci (2010) 1.93
RNA helicase Prp43 and its co-factor Pfa1 promote 20 to 18 S rRNA processing catalyzed by the endonuclease Nob1. J Biol Chem (2009) 1.93
Nuclear export and cytoplasmic processing of precursors to the 40S ribosomal subunits in mammalian cells. EMBO J (2005) 1.91
Biogenesis of cytosolic ribosomes requires the essential iron-sulphur protein Rli1p and mitochondria. EMBO J (2005) 1.87
The splicing ATPase prp43p is a component of multiple preribosomal particles. Mol Cell Biol (2005) 1.82
The 90S preribosome is a multimodular structure that is assembled through a hierarchical mechanism. Mol Cell Biol (2007) 1.82
The moving parts of the nucleolus. Histochem Cell Biol (2005) 1.81
Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol (2009) 1.81
Defining the pathway of cytoplasmic maturation of the 60S ribosomal subunit. Mol Cell (2010) 1.79
The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeast. EMBO J (2004) 1.77
Initial genomics of the human nucleolus. PLoS Genet (2010) 1.71
NOPdb: Nucleolar Proteome Database. Nucleic Acids Res (2006) 1.68
Functional link between ribosome formation and biogenesis of iron-sulfur proteins. EMBO J (2005) 1.67
A functional network involved in the recycling of nucleocytoplasmic pre-60S factors. J Cell Biol (2006) 1.64
Yeast Asc1p and mammalian RACK1 are functionally orthologous core 40S ribosomal proteins that repress gene expression. Mol Cell Biol (2004) 1.64
Transcription elongation by RNA polymerase I is linked to efficient rRNA processing and ribosome assembly. Mol Cell (2007) 1.59
Defining the order in which Nmd3p and Rpl10p load onto nascent 60S ribosomal subunits. Mol Cell Biol (2005) 1.55
Distinct cytoplasmic maturation steps of 40S ribosomal subunit precursors require hRio2. J Cell Biol (2009) 1.55
Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA (2004) 1.48
The putative NTPase Fap7 mediates cytoplasmic 20S pre-rRNA processing through a direct interaction with Rps14. Mol Cell Biol (2005) 1.46
Cytoplasmic recycling of 60S preribosomal factors depends on the AAA protein Drg1. Mol Cell Biol (2007) 1.46
Npa1p, a component of very early pre-60S ribosomal particles, associates with a subset of small nucleolar RNPs required for peptidyl transferase center modification. Mol Cell Biol (2004) 1.45
Suprainduction of p53 by disruption of 40S and 60S ribosome biogenesis leads to the activation of a novel G2/M checkpoint. Genes Dev (2012) 1.44
Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis. Cell (2016) 1.41
A ribosome-anchored chaperone network that facilitates eukaryotic ribosome biogenesis. J Cell Biol (2010) 1.41
A protein inventory of human ribosome biogenesis reveals an essential function of exportin 5 in 60S subunit export. PLoS Biol (2010) 1.39
Bud23 methylates G1575 of 18S rRNA and is required for efficient nuclear export of pre-40S subunits. Mol Cell Biol (2008) 1.38
Ribosomal protein and biogenesis factors affect multiple steps during movement of the Saccharomyces cerevisiae Ty1 retrotransposon. Mob DNA (2015) 1.38
Structure of the pre-60S ribosomal subunit with nuclear export factor Arx1 bound at the exit tunnel. Nat Struct Mol Biol (2012) 1.34
Ltv1 is required for efficient nuclear export of the ribosomal small subunit in Saccharomyces cerevisiae. Genetics (2006) 1.34
Nucleolar trafficking of nucleostemin family proteins: common versus protein-specific mechanisms. Mol Cell Biol (2007) 1.32
An overview of pre-ribosomal RNA processing in eukaryotes. Wiley Interdiscip Rev RNA (2014) 1.30
Bioinformatic analysis of the nucleolus. Biochem J (2003) 1.30
Nuclear recycling of the pre-60S ribosomal subunit-associated factor Arx1 depends on Rei1 in Saccharomyces cerevisiae. Mol Cell Biol (2006) 1.30
The AAA-ATPase Rea1 drives removal of biogenesis factors during multiple stages of 60S ribosome assembly. Mol Cell (2010) 1.26
Yvh1 is required for a late maturation step in the 60S biogenesis pathway. J Cell Biol (2009) 1.25
The homologous putative GTPases Grn1p from fission yeast and the human GNL3L are required for growth and play a role in processing of nucleolar pre-rRNA. Mol Biol Cell (2005) 1.25
The SUMO system controls nucleolar partitioning of a novel mammalian ribosome biogenesis complex. EMBO J (2011) 1.24
Quantitative analysis of snoRNA association with pre-ribosomes and release of snR30 by Rok1 helicase. EMBO Rep (2008) 1.24
The RP-Mdm2-p53 pathway and tumorigenesis. Oncotarget (2011) 1.23
Human ribosomal protein L13a is dispensable for canonical ribosome function but indispensable for efficient rRNA methylation. RNA (2007) 1.23
The Hsp40 chaperone Jjj1 is required for the nucleo-cytoplasmic recycling of preribosomal factors in Saccharomyces cerevisiae. RNA (2007) 1.22
NO66, a highly conserved dual location protein in the nucleolus and in a special type of synchronously replicating chromatin. Mol Biol Cell (2004) 1.21
Dim2p, a KH-domain protein required for small ribosomal subunit synthesis. RNA (2004) 1.20
The Caulobacter crescentus CgtAC protein cosediments with the free 50S ribosomal subunit. J Bacteriol (2004) 1.20
RNA length defines RNA export pathway. Genes Dev (2004) 1.18
Hmo1 is required for TOR-dependent regulation of ribosomal protein gene transcription. Mol Cell Biol (2007) 1.18
Structural consequences of nucleophosmin mutations in acute myeloid leukemia. J Biol Chem (2008) 1.18
The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA. Nucleic Acids Res (2010) 1.17
Exportin 7 defines a novel general nuclear export pathway. EMBO J (2004) 1.17
Ribosome stalk assembly requires the dual-specificity phosphatase Yvh1 for the exchange of Mrt4 with P0. J Cell Biol (2009) 1.17
Ribosomal protein L33 is required for ribosome biogenesis, subunit joining, and repression of GCN4 translation. Mol Cell Biol (2007) 1.16
The cytosolic J-protein, Jjj1, and Rei1 function in the removal of the pre-60 S subunit factor Arx1. J Biol Chem (2009) 1.15
Autoregulation of ribosome biosynthesis by a translational response in fission yeast. Mol Cell Biol (2006) 1.12
Comprehensive mutational analysis of yeast DEXD/H box RNA helicases required for small ribosomal subunit synthesis. Mol Cell Biol (2006) 1.11
Coexisting Liquid Phases Underlie Nucleolar Subcompartments. Cell (2016) 1.11
TOR regulates late steps of ribosome maturation in the nucleoplasm via Nog1 in response to nutrients. EMBO J (2006) 1.10
The power of AAA-ATPases on the road of pre-60S ribosome maturation--molecular machines that strip pre-ribosomal particles. Biochim Biophys Acta (2011) 1.09
The AAA ATPase Rix7 powers progression of ribosome biogenesis by stripping Nsa1 from pre-60S particles. J Cell Biol (2008) 1.09
Formation and nuclear export of tRNA, rRNA and mRNA is regulated by the ubiquitin ligase Rsp5p. EMBO Rep (2003) 1.09
Nuclear RNA-seq of single neurons reveals molecular signatures of activation. Nat Commun (2016) 1.08
Elucidation of the assembly events required for the recruitment of Utp20, Imp4 and Bms1 onto nascent pre-ribosomes. Nucleic Acids Res (2011) 1.07
The essential WD-repeat protein Rsa4p is required for rRNA processing and intra-nuclear transport of 60S ribosomal subunits. Nucleic Acids Res (2005) 1.05
The nuclear tRNA aminoacylation-dependent pathway may be the principal route used to export tRNA from the nucleus in Saccharomyces cerevisiae. Biochem J (2004) 1.04
The kinase activity of human Rio1 is required for final steps of cytoplasmic maturation of 40S subunits. Mol Biol Cell (2011) 1.04
60S ribosomal subunit assembly dynamics defined by semi-quantitative mass spectrometry of purified complexes. Nucleic Acids Res (2008) 1.04
Analysis of two human pre-ribosomal factors, bystin and hTsr1, highlights differences in evolution of ribosome biogenesis between yeast and mammals. Nucleic Acids Res (2010) 1.02
Synergistic defect in 60S ribosomal subunit assembly caused by a mutation of Rrs1p, a ribosomal protein L11-binding protein, and 3'-extension of 5S rRNA in Saccharomyces cerevisiae. Nucleic Acids Res (2005) 1.02
Structural and functional analysis of the archaeal endonuclease Nob1. Nucleic Acids Res (2011) 1.01
Characterization of Saccharomyces cerevisiae Npa2p (Urb2p) reveals a low-molecular-mass complex containing Dbp6p, Npa1p (Urb1p), Nop8p, and Rsa3p involved in early steps of 60S ribosomal subunit biogenesis. Mol Cell Biol (2006) 1.01
A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation. J Cell Biol (2014) 1.00
Ribosome biogenesis factors bind a nuclear envelope SUN domain protein to cluster yeast telomeres. EMBO J (2011) 0.99
Ribosomal proteins: functions beyond the ribosome. J Mol Cell Biol (2015) 0.99
Nucleolar separation from chromosomes during Aspergillus nidulans mitosis can occur without spindle forces. Mol Biol Cell (2009) 0.99
Las1L is a nucleolar protein required for cell proliferation and ribosome biogenesis. Mol Cell Biol (2010) 0.99
Two trypanosome-specific proteins are essential factors for 5S rRNA abundance and ribosomal assembly in Trypanosoma brucei. Eukaryot Cell (2007) 0.98
Role of Mex67-Mtr2 in the nuclear export of 40S pre-ribosomes. PLoS Genet (2012) 0.98
Mrd1p binds to pre-rRNA early during transcription independent of U3 snoRNA and is required for compaction of the pre-rRNA into small subunit processomes. Nucleic Acids Res (2008) 0.96
T. gondii RP promoters & knockdown reveal molecular pathways associated with proliferation and cell-cycle arrest. PLoS One (2010) 0.96
Nuclear PI3K signaling in cell growth and tumorigenesis. Front Cell Dev Biol (2015) 0.96
In vivo functional characterization of the Saccharomyces cerevisiae 60S biogenesis GTPase Nog1. Mol Genet Genomics (2007) 0.95
Dominant mutations in the late 40S biogenesis factor Ltv1 affect cytoplasmic maturation of the small ribosomal subunit in Saccharomyces cerevisiae. Genetics (2010) 0.95
Pol I transcription and pre-rRNA processing are coordinated in a transcription-dependent manner in mammalian cells. Mol Biol Cell (2006) 0.95
Nop53p is required for late 60S ribosome subunit maturation and nuclear export in yeast. RNA (2005) 0.95
The Saccharomyces cerevisiae 60 S ribosome biogenesis factor Tif6p is regulated by Hrr25p-mediated phosphorylation. J Biol Chem (2008) 0.95
NVL2 is a nucleolar AAA-ATPase that interacts with ribosomal protein L5 through its nucleolar localization sequence. Mol Biol Cell (2004) 0.95
Visualization of the joining of ribosomal subunits reveals the presence of 80S ribosomes in the nucleus. RNA (2013) 0.94
Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription. Mol Cell Biol (2004) 0.94
Basic mechanisms in RNA polymerase I transcription of the ribosomal RNA genes. Subcell Biochem (2013) 0.94
Single molecule fluorescence approaches shed light on intracellular RNAs. Chem Rev (2014) 0.94
TREX is a conserved complex coupling transcription with messenger RNA export. Nature (2002) 6.53
90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell (2002) 4.78
Exporting RNA from the nucleus to the cytoplasm. Nat Rev Mol Cell Biol (2007) 4.12
A conserved mRNA export machinery coupled to pre-mRNA splicing. Cell (2002) 3.88
60S pre-ribosome formation viewed from assembly in the nucleolus until export to the cytoplasm. EMBO J (2002) 3.62
The path from nucleolar 90S to cytoplasmic 40S pre-ribosomes. EMBO J (2003) 3.38
Sus1, a functional component of the SAGA histone acetylase complex and the nuclear pore-associated mRNA export machinery. Cell (2004) 3.16
Driving ribosome assembly. Biochim Biophys Acta (2009) 3.14
Recruitment of the human TREX complex to mRNA during splicing. Genes Dev (2005) 3.13
The mRNA export machinery requires the novel Sac3p-Thp1p complex to dock at the nucleoplasmic entrance of the nuclear pores. EMBO J (2002) 2.56
Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins. EMBO J (2002) 2.47
Insight into structure and assembly of the nuclear pore complex by utilizing the genome of a eukaryotic thermophile. Cell (2011) 2.46
Mechanochemical removal of ribosome biogenesis factors from nascent 60S ribosomal subunits. Cell (2009) 2.32
A proteome-wide approach identifies sumoylated substrate proteins in yeast. J Biol Chem (2004) 2.31
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export. Nat Cell Biol (2008) 2.27
Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export. Mol Cell (2009) 2.25
A Noc complex specifically involved in the formation and nuclear export of ribosomal 40 S subunits. J Biol Chem (2002) 1.98
Hrr25-dependent phosphorylation state regulates organization of the pre-40S subunit. Nature (2006) 1.95
RNA helicase Prp43 and its co-factor Pfa1 promote 20 to 18 S rRNA processing catalyzed by the endonuclease Nob1. J Biol Chem (2009) 1.93
The mRNA export factor Sus1 is involved in Spt/Ada/Gcn5 acetyltransferase-mediated H2B deubiquitinylation through its interaction with Ubp8 and Sgf11. Mol Biol Cell (2006) 1.83
Nuclear export of ribosomal 60S subunits by the general mRNA export receptor Mex67-Mtr2. Mol Cell (2007) 1.78
Structural basis for assembly and activation of the heterotetrameric SAGA histone H2B deubiquitinase module. Cell (2010) 1.66
Structural insights into tail-anchored protein binding and membrane insertion by Get3. Proc Natl Acad Sci U S A (2009) 1.63
Yeast centrin Cdc31 is linked to the nuclear mRNA export machinery. Nat Cell Biol (2004) 1.63
Unconventional tethering of Ulp1 to the transport channel of the nuclear pore complex by karyopherins. Nat Cell Biol (2003) 1.63
Membrane curvature induced by Arf1-GTP is essential for vesicle formation. Proc Natl Acad Sci U S A (2008) 1.63
Arx1 functions as an unorthodox nuclear export receptor for the 60S preribosomal subunit. Mol Cell (2007) 1.60
Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNA. EMBO J (2009) 1.53
Structural basis of histone H2A-H2B recognition by the essential chaperone FACT. Nature (2013) 1.47
Molecular basis for the functional interaction of dynein light chain with the nuclear-pore complex. Nat Cell Biol (2007) 1.45
Structural basis of the nic96 subcomplex organization in the nuclear pore channel. Mol Cell (2008) 1.42
The inner nuclear membrane protein Src1 associates with subtelomeric genes and alters their regulated gene expression. J Cell Biol (2008) 1.40
Rlp7p is associated with 60S preribosomes, restricted to the granular component of the nucleolus, and required for pre-rRNA processing. J Cell Biol (2002) 1.39
A pre-ribosome with a tadpole-like structure functions in ATP-dependent maturation of 60S subunits. Mol Cell (2004) 1.34
Structure of the pre-60S ribosomal subunit with nuclear export factor Arx1 bound at the exit tunnel. Nat Struct Mol Biol (2012) 1.34
Gene regulation by nucleoporins and links to cancer. Mol Cell (2010) 1.32
Eukaryotic ribosome biogenesis at a glance. J Cell Sci (2013) 1.28
Linking gene regulation to mRNA production and export. Curr Opin Cell Biol (2011) 1.28
Rea1, a dynein-related nuclear AAA-ATPase, is involved in late rRNA processing and nuclear export of 60 S subunits. J Biol Chem (2004) 1.27
Formation and nuclear export of preribosomes are functionally linked to the small-ubiquitin-related modifier pathway. Traffic (2006) 1.27
The AAA-ATPase Rea1 drives removal of biogenesis factors during multiple stages of 60S ribosome assembly. Mol Cell (2010) 1.26
Sem1 is a functional component of the nuclear pore complex-associated messenger RNA export machinery. J Cell Biol (2009) 1.25
Structure of the C-terminal FG-nucleoporin binding domain of Tap/NXF1. Nat Struct Biol (2002) 1.24
Reconstitution of Nup157 and Nup145N into the Nup84 complex. J Biol Chem (2005) 1.23
ATPase-dependent role of the atypical kinase Rio2 on the evolving pre-40S ribosomal subunit. Nat Struct Mol Biol (2012) 1.16
Purification of nuclear poly(A)-binding protein Nab2 reveals association with the yeast transcriptome and a messenger ribonucleoprotein core structure. J Biol Chem (2009) 1.15
Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export. Nucleic Acids Res (2012) 1.15
An endoribonuclease functionally linked to perinuclear mRNP quality control associates with the nuclear pore complexes. PLoS Biol (2009) 1.10
Nucleus-specific and cell cycle-regulated degradation of mitogen-activated protein kinase scaffold protein Ste5 contributes to the control of signaling competence. Mol Cell Biol (2008) 1.10
TOR regulates late steps of ribosome maturation in the nucleoplasm via Nog1 in response to nutrients. EMBO J (2006) 1.10
Structural basis for the assembly and nucleic acid binding of the TREX-2 transcription-export complex. Nat Struct Mol Biol (2012) 1.10
A versatile interaction platform on the Mex67-Mtr2 receptor creates an overlap between mRNA and ribosome export. EMBO J (2007) 1.10
Complex formation between Tap and p15 affects binding to FG-repeat nucleoporins and nucleocytoplasmic shuttling. J Biol Chem (2001) 1.09
The power of AAA-ATPases on the road of pre-60S ribosome maturation--molecular machines that strip pre-ribosomal particles. Biochim Biophys Acta (2011) 1.09
Formation and nuclear export of tRNA, rRNA and mRNA is regulated by the ubiquitin ligase Rsp5p. EMBO Rep (2003) 1.09
The AAA ATPase Rix7 powers progression of ribosome biogenesis by stripping Nsa1 from pre-60S particles. J Cell Biol (2008) 1.09
The NUG1 GTPase reveals and N-terminal RNA-binding domain that is essential for association with 60 S pre-ribosomal particles. J Biol Chem (2006) 1.07
Linear ubiquitin fusion to Rps31 and its subsequent cleavage are required for the efficient production and functional integrity of 40S ribosomal subunits. Mol Microbiol (2009) 1.07
The crystal structure of Ebp1 reveals a methionine aminopeptidase fold as binding platform for multiple interactions. FEBS Lett (2007) 1.04
The structure of Get4 reveals an alpha-solenoid fold adapted for multiple interactions in tail-anchored protein biogenesis. FEBS Lett (2010) 1.03
Structural characterization of a eukaryotic chaperone--the ribosome-associated complex. Nat Struct Mol Biol (2012) 1.03
Synchronizing nuclear import of ribosomal proteins with ribosome assembly. Science (2012) 1.02
Protein interfaces of the conserved Nup84 complex from Chaetomium thermophilum shown by crosslinking mass spectrometry and electron microscopy. Structure (2013) 1.01
Structural basis for the interaction between yeast Spt-Ada-Gcn5 acetyltransferase (SAGA) complex components Sgf11 and Sus1. J Biol Chem (2009) 1.00
Precise mapping of subunits in multiprotein complexes by a versatile electron microscopy label. Nat Struct Mol Biol (2010) 0.99
Structural basis for cooperativity of CRM1 export complex formation. Proc Natl Acad Sci U S A (2012) 0.98
Structural basis for the molecular evolution of SRP-GTPase activation by protein. Nat Struct Mol Biol (2011) 0.96
Two structurally distinct domains of the nucleoporin Nup170 cooperate to tether a subset of nucleoporins to nuclear pores. J Cell Biol (2009) 0.94
Rrp5p, Noc1p and Noc2p form a protein module which is part of early large ribosomal subunit precursors in S. cerevisiae. Nucleic Acids Res (2012) 0.94
New twist to nuclear import: When two travel together. Commun Integr Biol (2013) 0.90
Consistent mutational paths predict eukaryotic thermostability. BMC Evol Biol (2013) 0.89
An intron in the YRA1 gene is required to control Yra1 protein expression and mRNA export in yeast. EMBO Rep (2002) 0.89
Analysis of the yeast nucleoporin Nup188 reveals a conserved S-like structure with similarity to karyopherins. J Struct Biol (2011) 0.88
The yeast kinase Swe1 is required for proper entry into cell cycle after arrest due to ribosome biogenesis and protein synthesis defects. Cell Cycle (2004) 0.87
Mutational uncoupling of the role of Sus1 in nuclear pore complex targeting of an mRNA export complex and histone H2B deubiquitination. J Biol Chem (2009) 0.87
Monitoring spatiotemporal biogenesis of macromolecular assemblies by pulse-chase epitope labeling. Mol Cell (2012) 0.87
The tRNA aminoacylation co-factor Arc1p is excluded from the nucleus by an Xpo1p-dependent mechanism. FEBS Lett (2005) 0.85
Cell biology: Arrest by ribosome. Nature (2009) 0.84
The conserved Bud20 zinc finger protein is a new component of the ribosomal 60S subunit export machinery. Mol Cell Biol (2012) 0.84
Evidence for an evolutionary relationship between the large adaptor nucleoporin Nup192 and karyopherins. Proc Natl Acad Sci U S A (2014) 0.83
Nuclear export of tRNA. Results Probl Cell Differ (2002) 0.82
Coordinated nuclear import of RNA polymerase III subunits. Traffic (2006) 0.81
Probing the nucleoporin FG repeat network defines structural and functional features of the nuclear pore complex. J Cell Biol (2011) 0.80
Identification and characterization of a novel RanGTP-binding protein in the yeast Saccharomyces cerevisiae. J Biol Chem (2003) 0.77
Adjunct duties for karyopherins: regulating septin sumoylation. Dev Cell (2007) 0.75