Published in Mol Cell on July 01, 2002
60S pre-ribosome formation viewed from assembly in the nucleolus until export to the cytoplasm. EMBO J (2002) 3.62
The path from nucleolar 90S to cytoplasmic 40S pre-ribosomes. EMBO J (2003) 3.38
Dead-box proteins: a family affair--active and passive players in RNP-remodeling. Nucleic Acids Res (2006) 3.26
Yeast pre-rRNA processing and modification occur cotranscriptionally. Mol Cell (2010) 2.76
Why are there still over 1000 uncharacterized yeast genes? Genetics (2007) 2.71
Ribosome biogenesis in the yeast Saccharomyces cerevisiae. Genetics (2013) 2.70
Identification of cross-linked peptides from complex samples. Nat Methods (2012) 2.70
RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components. Genes Dev (2004) 2.48
Sequential protein association with nascent 60S ribosomal particles. Mol Cell Biol (2003) 2.40
The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosome. Nucleic Acids Res (2009) 2.28
Powering through ribosome assembly. RNA (2009) 2.19
The putative GTPases Nog1p and Lsg1p are required for 60S ribosomal subunit biogenesis and are localized to the nucleus and cytoplasm, respectively. Mol Cell Biol (2003) 1.99
Nob1p is required for cleavage of the 3' end of 18S rRNA. Mol Cell Biol (2003) 1.99
PIN domain of Nob1p is required for D-site cleavage in 20S pre-rRNA. RNA (2004) 1.94
Maturation of eukaryotic ribosomes: acquisition of functionality. Trends Biochem Sci (2010) 1.93
Nucleolus: the fascinating nuclear body. Histochem Cell Biol (2007) 1.87
The small-subunit processome is a ribosome assembly intermediate. Eukaryot Cell (2004) 1.84
The splicing ATPase prp43p is a component of multiple preribosomal particles. Mol Cell Biol (2005) 1.82
The 90S preribosome is a multimodular structure that is assembled through a hierarchical mechanism. Mol Cell Biol (2007) 1.82
Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol (2009) 1.81
The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeast. EMBO J (2004) 1.77
A pre-ribosome-associated HEAT-repeat protein is required for export of both ribosomal subunits. Genes Dev (2004) 1.76
When ribosomes go bad: diseases of ribosome biogenesis. Mol Biosyst (2010) 1.76
Surveillance of nuclear-restricted pre-ribosomes within a subnucleolar region of Saccharomyces cerevisiae. EMBO J (2006) 1.73
Late cytoplasmic maturation of the small ribosomal subunit requires RIO proteins in Saccharomyces cerevisiae. Mol Cell Biol (2003) 1.72
The splicing factor Prp43p, a DEAH box ATPase, functions in ribosome biogenesis. Mol Cell Biol (2006) 1.70
The Escherichia coli GTPase CgtAE is involved in late steps of large ribosome assembly. J Bacteriol (2006) 1.67
The small subunit processome in ribosome biogenesis—progress and prospects. Wiley Interdiscip Rev RNA (2011) 1.66
The WD40 repeat protein WDR-23 functions with the CUL4/DDB1 ubiquitin ligase to regulate nuclear abundance and activity of SKN-1 in Caenorhabditis elegans. Mol Cell Biol (2009) 1.60
Recruitment of factors linking transcription and processing of pre-rRNA to NOR chromatin is UBF-dependent and occurs independent of transcription in human cells. Genes Dev (2007) 1.57
Defining the order in which Nmd3p and Rpl10p load onto nascent 60S ribosomal subunits. Mol Cell Biol (2005) 1.55
Confirmation of organized modularity in the yeast interactome. PLoS Biol (2007) 1.52
Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA (2004) 1.48
Autoregulation in the biosynthesis of ribosomes. Mol Cell Biol (2003) 1.47
The putative NTPase Fap7 mediates cytoplasmic 20S pre-rRNA processing through a direct interaction with Rps14. Mol Cell Biol (2005) 1.46
Npa1p, a component of very early pre-60S ribosomal particles, associates with a subset of small nucleolar RNPs required for peptidyl transferase center modification. Mol Cell Biol (2004) 1.45
Ribosome biogenesis is sensed at the Start cell cycle checkpoint. Mol Biol Cell (2006) 1.43
The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes. Nucleic Acids Res (2003) 1.41
A protein inventory of human ribosome biogenesis reveals an essential function of exportin 5 in 60S subunit export. PLoS Biol (2010) 1.39
The nucleolus: a model for the organization of nuclear functions. Histochem Cell Biol (2006) 1.39
Tor1 and CK2 kinases control a switch between alternative ribosome biogenesis pathways in a growth-dependent manner. PLoS Biol (2017) 1.39
Ytm1, Nop7, and Erb1 form a complex necessary for maturation of yeast 66S preribosomes. Mol Cell Biol (2005) 1.39
The helicase Has1p is required for snoRNA release from pre-rRNA. Mol Cell Biol (2006) 1.34
Sno/scaRNAbase: a curated database for small nucleolar RNAs and cajal body-specific RNAs. Nucleic Acids Res (2006) 1.33
The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation. Proc Natl Acad Sci U S A (2006) 1.31
An overview of pre-ribosomal RNA processing in eukaryotes. Wiley Interdiscip Rev RNA (2014) 1.30
Nuclear recycling of the pre-60S ribosomal subunit-associated factor Arx1 depends on Rei1 in Saccharomyces cerevisiae. Mol Cell Biol (2006) 1.30
A direct interaction between the Utp6 half-a-tetratricopeptide repeat domain and a specific peptide in Utp21 is essential for efficient pre-rRNA processing. Mol Cell Biol (2008) 1.30
The small subunit processome is required for cell cycle progression at G1. Mol Biol Cell (2004) 1.26
Transcriptional regulation of human small nuclear RNA genes. Biochim Biophys Acta (2008) 1.25
Yvh1 is required for a late maturation step in the 60S biogenesis pathway. J Cell Biol (2009) 1.25
Potential roles for ubiquitin and the proteasome during ribosome biogenesis. Mol Cell Biol (2006) 1.25
The homologous putative GTPases Grn1p from fission yeast and the human GNL3L are required for growth and play a role in processing of nucleolar pre-rRNA. Mol Biol Cell (2005) 1.25
The nuclear poly(A) polymerase and Exosome cofactor Trf5 is recruited cotranscriptionally to nucleolar surveillance. RNA (2009) 1.24
The pre-ribosomal network. Nucleic Acids Res (2003) 1.24
Age-dependent evolution of the yeast protein interaction network suggests a limited role of gene duplication and divergence. PLoS Comput Biol (2008) 1.23
The initial U3 snoRNA:pre-rRNA base pairing interaction required for pre-18S rRNA folding revealed by in vivo chemical probing. Nucleic Acids Res (2011) 1.23
Enp1, a yeast protein associated with U3 and U14 snoRNAs, is required for pre-rRNA processing and 40S subunit synthesis. Nucleic Acids Res (2003) 1.22
5'-end surveillance by Xrn2 acts as a shared mechanism for mammalian pre-rRNA maturation and decay. Nucleic Acids Res (2010) 1.22
Role of pre-rRNA base pairing and 80S complex formation in subnucleolar localization of the U3 snoRNP. Mol Cell Biol (2004) 1.21
Dim2p, a KH-domain protein required for small ribosomal subunit synthesis. RNA (2004) 1.20
The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA. Nucleic Acids Res (2010) 1.17
Ribosomal protein L33 is required for ribosome biogenesis, subunit joining, and repression of GCN4 translation. Mol Cell Biol (2007) 1.16
Eukaryotic 5S rRNA biogenesis. Wiley Interdiscip Rev RNA (2011) 1.15
Nop9 is an RNA binding protein present in pre-40S ribosomes and required for 18S rRNA synthesis in yeast. RNA (2007) 1.12
Comprehensive mutational analysis of yeast DEXD/H box RNA helicases required for small ribosomal subunit synthesis. Mol Cell Biol (2006) 1.11
The E. coli RhlE RNA helicase regulates the function of related RNA helicases during ribosome assembly. RNA (2007) 1.11
Characterization of the ATPase and unwinding activities of the yeast DEAD-box protein Has1p and the analysis of the roles of the conserved motifs. Nucleic Acids Res (2005) 1.09
Role and dynamics of the ribosomal protein P0 and its related trans-acting factor Mrt4 during ribosome assembly in Saccharomyces cerevisiae. Nucleic Acids Res (2009) 1.09
The 5' external transcribed spacer in mouse ribosomal RNA contains two cleavage sites. RNA (2008) 1.09
Formation and nuclear export of tRNA, rRNA and mRNA is regulated by the ubiquitin ligase Rsp5p. EMBO Rep (2003) 1.09
Elucidation of the assembly events required for the recruitment of Utp20, Imp4 and Bms1 onto nascent pre-ribosomes. Nucleic Acids Res (2011) 1.07
Trm112 is required for Bud23-mediated methylation of the 18S rRNA at position G1575. Mol Cell Biol (2012) 1.07
The essential WD-repeat protein Rsa4p is required for rRNA processing and intra-nuclear transport of 60S ribosomal subunits. Nucleic Acids Res (2005) 1.05
Esf2p, a U3-associated factor required for small-subunit processome assembly and compaction. Mol Cell Biol (2005) 1.04
Analysis of two human pre-ribosomal factors, bystin and hTsr1, highlights differences in evolution of ribosome biogenesis between yeast and mammals. Nucleic Acids Res (2010) 1.02
Genetic evidence for 18S rRNA binding and an Rps19p assembly function of yeast nucleolar protein Nep1p. Mol Genet Genomics (2006) 1.02
Characterization of Saccharomyces cerevisiae Npa2p (Urb2p) reveals a low-molecular-mass complex containing Dbp6p, Npa1p (Urb1p), Nop8p, and Rsa3p involved in early steps of 60S ribosomal subunit biogenesis. Mol Cell Biol (2006) 1.01
Ribosomal protein L35 is required for 27SB pre-rRNA processing in Saccharomyces cerevisiae. Nucleic Acids Res (2010) 1.01
Saccharomyces cerevisiae ribosomal protein L26 is not essential for ribosome assembly and function. Mol Cell Biol (2012) 1.01
Stage-specific assembly events of the 6-MDa small-subunit processome initiate eukaryotic ribosome biogenesis. Nat Struct Mol Biol (2015) 0.99
Components of U3 snoRNA-containing complexes shuttle between nuclei and the cytoplasm and differentially localize in nucleoli: implications for assembly and function. Mol Biol Cell (2003) 0.99
DExD/H-box RNA helicases in ribosome biogenesis. RNA Biol (2012) 0.99
Intranucleolar sites of ribosome biogenesis defined by the localization of early binding ribosomal proteins. J Cell Biol (2007) 0.99
Mammalian DEAD box protein Ddx51 acts in 3' end maturation of 28S rRNA by promoting the release of U8 snoRNA. Mol Cell Biol (2010) 0.98
Role of Mex67-Mtr2 in the nuclear export of 40S pre-ribosomes. PLoS Genet (2012) 0.98
Transcription of genes encoding trans-acting factors required for rRNA maturation/ribosomal subunit assembly is coordinately regulated with ribosomal protein genes and involves Rap1 in Saccharomyces cerevisiae. Nucleic Acids Res (2003) 0.97
Xenopus U3 snoRNA docks on pre-rRNA through a novel base-pairing interaction. RNA (2004) 0.97
Mrd1p binds to pre-rRNA early during transcription independent of U3 snoRNA and is required for compaction of the pre-rRNA into small subunit processomes. Nucleic Acids Res (2008) 0.96
An evolutionary intra-molecular shift in the preferred U3 snoRNA binding site on pre-ribosomal RNA. Nucleic Acids Res (2005) 0.96
RNA chaperones stimulate formation and yield of the U3 snoRNA-Pre-rRNA duplexes needed for eukaryotic ribosome biogenesis. J Mol Biol (2009) 0.96
Nuclear PI3K signaling in cell growth and tumorigenesis. Front Cell Dev Biol (2015) 0.96
In vivo functional characterization of the Saccharomyces cerevisiae 60S biogenesis GTPase Nog1. Mol Genet Genomics (2007) 0.95
Nop53p is required for late 60S ribosome subunit maturation and nuclear export in yeast. RNA (2005) 0.95
Bystin in human cancer cells: intracellular localization and function in ribosome biogenesis. Biochem J (2007) 0.95
Pol I transcription and pre-rRNA processing are coordinated in a transcription-dependent manner in mammalian cells. Mol Biol Cell (2006) 0.95
Dominant mutations in the late 40S biogenesis factor Ltv1 affect cytoplasmic maturation of the small ribosomal subunit in Saccharomyces cerevisiae. Genetics (2010) 0.95
Functional gene expression profiling in yeast implicates translational dysfunction in mutant huntingtin toxicity. J Biol Chem (2010) 0.94
Visualization of the joining of ribosomal subunits reveals the presence of 80S ribosomes in the nucleus. RNA (2013) 0.94
Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature (2002) 45.19
Proteome survey reveals modularity of the yeast cell machinery. Nature (2006) 20.77
Coding-sequence determinants of gene expression in Escherichia coli. Science (2009) 8.38
Computational prediction of proteotypic peptides for quantitative proteomics. Nat Biotechnol (2006) 7.56
RNA degradation by the exosome is promoted by a nuclear polyadenylation complex. Cell (2005) 7.37
A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. Nat Cell Biol (2004) 7.23
Quantitative mass spectrometry in proteomics: a critical review. Anal Bioanal Chem (2007) 6.80
Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors. Nat Biotechnol (2007) 6.56
TREX is a conserved complex coupling transcription with messenger RNA export. Nature (2002) 6.53
The many pathways of RNA degradation. Cell (2009) 5.31
RNA-quality control by the exosome. Nat Rev Mol Cell Biol (2006) 5.26
Making ribosomes. Curr Opin Cell Biol (2002) 5.20
Phospho.ELM: a database of experimentally verified phosphorylation sites in eukaryotic proteins. BMC Bioinformatics (2004) 4.44
Pre-ribosomes on the road from the nucleolus to the cytoplasm. Trends Cell Biol (2003) 4.31
Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding. Cell (2013) 4.28
Human Proteinpedia enables sharing of human protein data. Nat Biotechnol (2008) 4.21
Exporting RNA from the nucleus to the cytoplasm. Nat Rev Mol Cell Biol (2007) 4.12
Proteome organization in a genome-reduced bacterium. Science (2009) 3.97
A conserved mRNA export machinery coupled to pre-mRNA splicing. Cell (2002) 3.88
60S pre-ribosome formation viewed from assembly in the nucleolus until export to the cytoplasm. EMBO J (2002) 3.62
The path from nucleolar 90S to cytoplasmic 40S pre-ribosomes. EMBO J (2003) 3.38
Sus1, a functional component of the SAGA histone acetylase complex and the nuclear pore-associated mRNA export machinery. Cell (2004) 3.16
Driving ribosome assembly. Biochim Biophys Acta (2009) 3.14
Recruitment of the human TREX complex to mRNA during splicing. Genes Dev (2005) 3.13
Identification of protein binding sites on U3 snoRNA and pre-rRNA by UV cross-linking and high-throughput analysis of cDNAs. Proc Natl Acad Sci U S A (2009) 3.04
ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes. Mol Cell (2003) 3.01
A ncRNA modulates histone modification and mRNA induction in the yeast GAL gene cluster. Mol Cell (2008) 2.97
Functional architecture of RNA polymerase I. Cell (2007) 2.86
Proteomics: a pragmatic perspective. Nat Biotechnol (2010) 2.81
Yeast pre-rRNA processing and modification occur cotranscriptionally. Mol Cell (2010) 2.76
Roles of eukaryotic ribosomal proteins in maturation and transport of pre-18S rRNA and ribosome function. Mol Cell (2005) 2.65
The mRNA export machinery requires the novel Sac3p-Thp1p complex to dock at the nucleoplasmic entrance of the nuclear pores. EMBO J (2002) 2.56
HDAC6-p97/VCP controlled polyubiquitin chain turnover. EMBO J (2006) 2.52
Robust and sensitive iTRAQ quantification on an LTQ Orbitrap mass spectrometer. Mol Cell Proteomics (2008) 2.51
Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins. EMBO J (2002) 2.47
Insight into structure and assembly of the nuclear pore complex by utilizing the genome of a eukaryotic thermophile. Cell (2011) 2.46
Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis. Genes Dev (2010) 2.44
Quantitative mass spectrometry in proteomics: critical review update from 2007 to the present. Anal Bioanal Chem (2012) 2.42
An NMD pathway in yeast involving accelerated deadenylation and exosome-mediated 3'-->5' degradation. Mol Cell (2003) 2.41
Prp43 bound at different sites on the pre-rRNA performs distinct functions in ribosome synthesis. Mol Cell (2009) 2.36
Mechanochemical removal of ribosome biogenesis factors from nascent 60S ribosomal subunits. Cell (2009) 2.32
A proteome-wide approach identifies sumoylated substrate proteins in yeast. J Biol Chem (2004) 2.31
The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosome. Nucleic Acids Res (2009) 2.28
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export. Nat Cell Biol (2008) 2.27
Ssf1p prevents premature processing of an early pre-60S ribosomal particle. Mol Cell (2002) 2.27
Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export. Mol Cell (2009) 2.25
The exosome subunit Rrp44 plays a direct role in RNA substrate recognition. Mol Cell (2007) 2.18
Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks. Mol Cell (2011) 2.16
Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex. Mol Cell (2008) 2.09
Processing of 3'-extended read-through transcripts by the exosome can generate functional mRNAs. Mol Cell (2002) 2.05
The nuclear RNA polymerase II surveillance system targets polymerase III transcripts. EMBO J (2011) 1.99
Nob1p is required for cleavage of the 3' end of 18S rRNA. Mol Cell Biol (2003) 1.99
A Noc complex specifically involved in the formation and nuclear export of ribosomal 40 S subunits. J Biol Chem (2002) 1.98
Yeast Trf5p is a nuclear poly(A) polymerase. EMBO Rep (2006) 1.97
Enterococcus faecalis metalloprotease compromises epithelial barrier and contributes to intestinal inflammation. Gastroenterology (2011) 1.96
Hrr25-dependent phosphorylation state regulates organization of the pre-40S subunit. Nature (2006) 1.95
PIN domain of Nob1p is required for D-site cleavage in 20S pre-rRNA. RNA (2004) 1.94
A large synthetic peptide and phosphopeptide reference library for mass spectrometry-based proteomics. Nat Biotechnol (2013) 1.93
RNA helicase Prp43 and its co-factor Pfa1 promote 20 to 18 S rRNA processing catalyzed by the endonuclease Nob1. J Biol Chem (2009) 1.93
Trf4 targets ncRNAs from telomeric and rDNA spacer regions and functions in rDNA copy number control. EMBO J (2007) 1.92
Ribosome synthesis meets the cell cycle. Curr Opin Microbiol (2004) 1.92
Confident phosphorylation site localization using the Mascot Delta Score. Mol Cell Proteomics (2010) 1.90
Computer-aided design of a PDZ domain to recognize new target sequences. Nat Struct Biol (2002) 1.89
Biogenesis of cytosolic ribosomes requires the essential iron-sulphur protein Rli1p and mitochondria. EMBO J (2005) 1.87
Cross-linking, ligation, and sequencing of hybrids reveals RNA-RNA interactions in yeast. Proc Natl Acad Sci U S A (2011) 1.85
The mRNA export factor Sus1 is involved in Spt/Ada/Gcn5 acetyltransferase-mediated H2B deubiquitinylation through its interaction with Ubp8 and Sgf11. Mol Biol Cell (2006) 1.83
A public-private partnership to unlock the untargeted kinome. Nat Chem Biol (2013) 1.83
Profiling core proteomes of human cell lines by one-dimensional PAGE and liquid chromatography-tandem mass spectrometry. Mol Cell Proteomics (2003) 1.82
Nuclear export of ribosomal 60S subunits by the general mRNA export receptor Mex67-Mtr2. Mol Cell (2007) 1.78
Global proteome analysis of the NCI-60 cell line panel. Cell Rep (2013) 1.77
A pre-ribosome-associated HEAT-repeat protein is required for export of both ribosomal subunits. Genes Dev (2004) 1.76
Cracking pre-40S ribosomal subunit structure by systematic analyses of RNA-protein cross-linking. EMBO J (2010) 1.74
Surveillance of nuclear-restricted pre-ribosomes within a subnucleolar region of Saccharomyces cerevisiae. EMBO J (2006) 1.73
Rrp47p is an exosome-associated protein required for the 3' processing of stable RNAs. Mol Cell Biol (2003) 1.73
Discovery of O-GlcNAc-6-phosphate modified proteins in large-scale phosphoproteomics data. Mol Cell Proteomics (2012) 1.71
A cluster of ribosome synthesis factors regulate pre-rRNA folding and 5.8S rRNA maturation by the Rat1 exonuclease. EMBO J (2011) 1.69