Published in Metabolism on May 01, 2003
Inflammation in diabetic nephropathy. Mediators Inflamm (2012) 1.81
Interleukin-33 induces protective effects in adipose tissue inflammation during obesity in mice. Circ Res (2010) 1.80
What is the mechanism of microalbuminuria in diabetes: a role for the glomerular endothelium? Diabetologia (2008) 1.70
The role of interferon-gamma in the increased tuberculosis risk in type 2 diabetes mellitus. Eur J Clin Microbiol Infect Dis (2007) 1.58
Quercetin and allopurinol ameliorate kidney injury in STZ-treated rats with regulation of renal NLRP3 inflammasome activation and lipid accumulation. PLoS One (2012) 1.21
Cardiovascular diabetology in the core of a novel interleukins classification: the bad, the good and the aloof. Cardiovasc Diabetol (2003) 1.09
Inflammatory cytokines in diabetic nephropathy. J Diabetes Res (2015) 1.01
Insulin-like growth factor binding protein-3 mediates cytokine-induced mesangial cell apoptosis. Growth Horm IGF Res (2005) 0.99
Phosphorylation of pleckstrin increases proinflammatory cytokine secretion by mononuclear phagocytes in diabetes mellitus. J Immunol (2007) 0.98
Inflammation and oxidative stress in diabetic nephropathy: new insights on its inhibition as new therapeutic targets. J Diabetes Res (2013) 0.97
Beneficial effect of TNF-α inhibition on diabetic peripheral neuropathy. J Neuroinflammation (2013) 0.94
Inflammation in diabetic kidney disease. World J Diabetes (2014) 0.91
TNF-α and microalbuminuria in patients with type 2 diabetes mellitus. J Diabetes Res (2014) 0.90
Intracellular signalling by C-peptide. Exp Diabetes Res (2008) 0.89
Serum amyloid A and inflammation in diabetic kidney disease and podocytes. Lab Invest (2014) 0.86
IL-1 family members in the pathogenesis and treatment of metabolic disease: Focus on adipose tissue inflammation and insulin resistance. Cytokine (2015) 0.85
C-Peptide and its intracellular signaling. Rev Diabet Stud (2009) 0.84
The role of inflammatory pathway genetic variation on maternal metabolic phenotypes during pregnancy. PLoS One (2012) 0.83
Effects of combined aerobic and resistance training on the glycolipid metabolism and inflammation levels in type 2 diabetes mellitus. J Phys Ther Sci (2015) 0.83
Genetic disruption of soluble epoxide hydrolase is protective against streptozotocin-induced diabetic nephropathy. Am J Physiol Endocrinol Metab (2012) 0.83
Elevated levels of serum IL-12 and IL-18 are associated with lower frequencies of CD4(+)CD25 (high)FOXP3 (+) regulatory t cells in young patients with type 1 diabetes. Inflammation (2014) 0.83
Pancreatic regulation of glucose homeostasis. Exp Mol Med (2016) 0.81
A Study to Investigate the Efficacy and Safety of an Anti-Interleukin-18 Monoclonal Antibody in the Treatment of Type 2 Diabetes Mellitus. PLoS One (2016) 0.79
Matching experiments across species using expression values and textual information. Bioinformatics (2012) 0.79
Interleukin-1 Family Cytokines in Liver Diseases. Mediators Inflamm (2015) 0.79
Melatonin Attenuates Contrast-Induced Nephropathy in Diabetic Rats: The Role of Interleukin-33 and Oxidative Stress. Mediators Inflamm (2016) 0.78
Inflammation and pathogenesis of diabetic nephropathy. Metabolism (2004) 0.78
Diabetic Kidney Disease: Pathophysiology and Therapeutic Targets. J Diabetes Res (2015) 0.77
Anti-inflammatory and Antioxidative Activities of Safranal in the Reduction of Renal Dysfunction and Damage that Occur in Diabetic Nephropathy. Inflammation (2015) 0.77
Systemic and renal lipids in kidney disease development and progression. Am J Physiol Renal Physiol (2015) 0.77
Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury. J Clin Invest (2016) 0.76
Diabetes-Induced Reactive Oxygen Species: Mechanism of Their Generation and Role in Renal Injury. J Diabetes Res (2017) 0.75
Serum Interleukin-18 and Its Gene Haplotypes Profile as Predictors in Patients with Diabetic Nephropathy. Open Access Maced J Med Sci (2016) 0.75
Renal Outcomes of Pioglitazone Compared with Acarbose in Diabetic Patients: A Randomized Controlled Study. PLoS One (2016) 0.75
Biomarkers of Renal Disease and Progression in Patients with Diabetes. J Clin Med (2015) 0.75
Interleukin-18 polymorphism as an inflammatory index in metabolic syndrome: A preliminary study. World J Diabetes (2017) 0.75
B cells in type 1 diabetes mellitus and diabetic kidney disease. Nat Rev Nephrol (2017) 0.75
Beneficial Effect of Aqueous Garlic Extract on Inflammation and Oxidative Stress Status in the Kidneys of Type 1 Diabetic Rats. Indian J Clin Biochem (2016) 0.75
The prevalence of primary open-angle glaucoma in Japanese: the Tajimi Study. Ophthalmology (2004) 4.95
Refractive errors in an elderly Japanese population: the Tajimi study. Ophthalmology (2008) 2.28
Risk factors for open-angle glaucoma in a Japanese population: the Tajimi Study. Ophthalmology (2006) 2.14
Prevalence and causes of low vision and blindness in a Japanese adult population: the Tajimi Study. Ophthalmology (2006) 1.81
Roles of caspase-1 in Listeria infection in mice. Int Immunol (2004) 1.78
EphA2 overexpression correlates with poor prognosis in esophageal squamous cell carcinoma. Int J Cancer (2003) 1.68
The incremental effect of positron emission tomography on diagnostic accuracy in the initial staging of esophageal carcinoma. Cancer (2005) 1.64
Phase I/IIa trial of autologous formalin-fixed tumor vaccine concomitant with fractionated radiotherapy for newly diagnosed glioblastoma. Clinical article. J Neurosurg (2011) 1.63
Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane. J Biol Chem (2002) 1.61
Menopause, but not age, is an independent risk factor for fasting plasma glucose levels in nondiabetic women. Menopause (2007) 1.59
Increased frequency of metabolic syndrome and its individual metabolic abnormalities in Japanese patients with primary gout. J Clin Rheumatol (2010) 1.51
Evaluation of optineurin sequence variations in 1,048 patients with open-angle glaucoma. Am J Ophthalmol (2003) 1.43
Association of Toll-like receptor 4 gene polymorphisms with normal tension glaucoma. Invest Ophthalmol Vis Sci (2008) 1.43
Retroperitoneal ancient schwannoma presenting as an adrenal incidentaloma: CT and MR findings. Magn Reson Imaging (2006) 1.42
A1C but not serum glycated albumin is elevated in late pregnancy owing to iron deficiency. Diabetes Care (2008) 1.35
Interleukin-18-mediated microglia/astrocyte interaction in the spinal cord enhances neuropathic pain processing after nerve injury. J Neurosci (2008) 1.34
Clinical trial of autologous formalin-fixed tumor vaccine for glioblastoma multiforme patients. Cancer Sci (2007) 1.30
Treatment of arthritis with a selective inhibitor of c-Fos/activator protein-1. Nat Biotechnol (2008) 1.23
Reactive oxygen species (ROS) control the expression of Bcl-2 family proteins by regulating their phosphorylation and ubiquitination. Cancer Sci (2004) 1.21
Genetic alterations in esophageal cancer. Surg Today (2005) 1.20
The involvement of hypoxia-inducible factor-1alpha in the susceptibility to gamma-rays and chemotherapeutic drugs of oral squamous cell carcinoma cells. Int J Cancer (2007) 1.18
Mechanism of HIF-1alpha-dependent suppression of hypoxia-induced apoptosis in squamous cell carcinoma cells. Cancer Sci (2005) 1.18
Reduced expression of transforming growth factor-beta receptors is an unfavorable prognostic factor in human esophageal squamous cell carcinoma. Int J Cancer (2003) 1.17
Involvement of heat-shock protein 90 in the interleukin-6-mediated signaling pathway through STAT3. Biochem Biophys Res Commun (2003) 1.15
Laser scanning tomography of optic discs of the normal Japanese population in a population-based setting. Ophthalmology (2008) 1.15
Effect of TNF-alpha inhibition on urinary albumin excretion in experimental diabetic rats. Acta Diabetol (2007) 1.13
Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice. Hum Mol Genet (2010) 1.13
Detection of IDH1 mutation in human gliomas: comparison of immunohistochemistry and sequencing. Brain Tumor Pathol (2011) 1.12
Nationwide survey for bisphosphonate-related osteonecrosis of the jaws in Japan. J Oral Maxillofac Surg (2011) 1.11
Prognostic significance of EpCAM expression in human esophageal cancer. Int J Oncol (2007) 1.11
Hepatoma-derived growth factor induces tumorigenesis in vivo through both direct angiogenic activity and induction of vascular endothelial growth factor. Cancer Sci (2003) 1.11
Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid). Clin Chim Acta (2005) 1.11
Primary squamous cell carcinoma of the stomach: a case report with immunohistochemical and molecular biologic studies. Hepatogastroenterology (2005) 1.10
Mild encephalitis/encephalopathy with a reversible splenial lesion: evaluation by diffusion tensor imaging. Two case reports. Neurol Med Chir (Tokyo) (2010) 1.10
Effects of topiroxostat on the serum urate levels and urinary albumin excretion in hyperuricemic stage 3 chronic kidney disease patients with or without gout. Clin Exp Nephrol (2014) 1.09
Green tea polyphenols induce differentiation and proliferation in epidermal keratinocytes. J Pharmacol Exp Ther (2003) 1.08
Regulation of transforming growth factor-beta signaling by protein inhibitor of activated STAT, PIASy through Smad3. J Biol Chem (2003) 1.08
The clinical application of (18)F-fluorodeoxyglucose positron emission tomography to predict survival in patients with operable esophageal cancer. Cancer (2009) 1.07
ECA39 is a novel distant metastasis-related biomarker in colorectal cancer. World J Gastroenterol (2006) 1.07
Enhanced optineurin E50K-TBK1 interaction evokes protein insolubility and initiates familial primary open-angle glaucoma. Hum Mol Genet (2013) 1.06
Comparison between whole-body positron emission tomography and bone scintigraphy in evaluating bony metastases of esophageal carcinomas. Anticancer Res (2005) 1.06
Modulation of TLR4 signaling by a novel adaptor protein signal-transducing adaptor protein-2 in macrophages. J Immunol (2006) 1.05
IL18 polymorphism is associated with an increased risk of Crohn's disease. J Gastroenterol (2002) 1.04
Nuclear factor kappa B decoy oligodeoxynucleotides prevent endotoxin-induced fatal liver failure in a murine model. Hepatology (2003) 1.04
Phase I/II trial of hyperfractionated concomitant boost proton radiotherapy for supratentorial glioblastoma multiforme. Int J Radiat Oncol Biol Phys (2009) 1.04
NS-398, a selective cyclooxygenase 2 inhibitor, inhibited cell growth and induced cell cycle arrest in human hepatocellular carcinoma cell lines. Int J Cancer (2002) 1.03
Preoperative endovascular embolization for hemangioblastoma in the posterior fossa. Neurol Med Chir (Tokyo) (2012) 1.03
Phase 2 randomized clinical study of a Rho kinase inhibitor, K-115, in primary open-angle glaucoma and ocular hypertension. Am J Ophthalmol (2013) 1.02
Immunohistochemical detection of IDH1 mutation, p53, and internexin as prognostic factors of glial tumors. J Neurooncol (2012) 1.01
A new model of retinal photoreceptor cell degeneration induced by a chemical hypoxia-mimicking agent, cobalt chloride. Brain Res (2006) 1.00
Nonalcoholic fatty liver disease in adult hypopituitary patients with GH deficiency and the impact of GH replacement therapy. Eur J Endocrinol (2012) 1.00
Contribution of TIR domain-containing adapter inducing IFN-beta-mediated IL-18 release to LPS-induced liver injury in mice. J Hepatol (2009) 0.99
Target intraocular pressure for stability of visual field loss progression in normal-tension glaucoma. Jpn J Ophthalmol (2010) 0.98
Lucica GA-L glycated albumin assay kit: a new diagnostic test for diabetes mellitus. Mol Diagn Ther (2010) 0.98
Immunodeficiency reduces neural stem/progenitor cell apoptosis and enhances neurogenesis in the cerebral cortex after stroke. J Neurosci Res (2010) 0.98
Receptor for advanced glycation end products regulates adipocyte hypertrophy and insulin sensitivity in mice: involvement of Toll-like receptor 2. Diabetes (2012) 0.98
Transdifferentiation into biliary ductular cells of hepatocytes transplanted into the spleen. Pathology (2008) 0.98
Physical and functional interactions between Daxx and DNA methyltransferase 1-associated protein, DMAP1. J Immunol (2004) 0.98
IL-18 together with anti-CD3 antibody induces human Th1 cells to produce Th1- and Th2-cytokines and IL-8. Int Immunol (2004) 0.97
Expression of cyclooxygenase 2 and cytosolic phospholipase A(2) in the liver tissue of patients with chronic hepatitis and liver cirrhosis. Hepatol Res (2002) 0.97
A novel approach to the prevention of postoperative delirium in the elderly after gastrointestinal surgery. Surg Today (2002) 0.97
Huge pelvic mass secondary to wear debris causing ureteral obstruction. J Arthroplasty (2005) 0.96
Acute subdural hematoma without subarachnoid hemorrhage caused by ruptured A1-A2 junction aneurysm. Case report. Neurol Med Chir (Tokyo) (2012) 0.96
Uric acid induces oxidative stress and growth inhibition by activating adenosine monophosphate-activated protein kinase and extracellular signal-regulated kinase signal pathways in pancreatic β cells. Mol Cell Endocrinol (2013) 0.96
The role of IL-18 in blood-stage immunity against murine malaria Plasmodium yoelii 265 and Plasmodium berghei ANKA. J Immunol (2002) 0.96
Efficacy of keishibukuryogan, a traditional Japanese herbal medicine, in treating cold sensation and numbness after stroke: clinical improvement and skin temperature normalization in 22 stroke patients. Neurol Med Chir (Tokyo) (2010) 0.96
Results of long-term monitoring of normal-tension glaucoma patients receiving medical therapy: results of an 18-year follow-up. Graefes Arch Clin Exp Ophthalmol (2014) 0.96
A novel calpain inhibitor, ((1S)-1-((((1S)-1-Benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester (SNJ-1945), reduces murine retinal cell death in vitro and in vivo. J Pharmacol Exp Ther (2009) 0.95
Allopurinol improves cardiac dysfunction after ischemia-reperfusion via reduction of oxidative stress in isolated perfused rat hearts. Circ J (2003) 0.95
Zoledronic acid-induced expansion of γδ T cells from early-stage breast cancer patients: effect of IL-18 on helper NK cells. Cancer Immunol Immunother (2012) 0.95
Correlation between laminin-5 gamma2 chain and epidermal growth factor receptor expression in esophageal squamous cell carcinomas. Oncology (2005) 0.95
Thresholds of various glycemic measures for diagnosing diabetes based on prevalence of retinopathy in community-dwelling Japanese subjects: the Hisayama Study. Cardiovasc Diabetol (2014) 0.95
Sentinel lymph nodes with technetium-99m colloidal rhenium sulfide in patients with esophageal carcinoma. Cancer (2003) 0.95
Expression of vascular endothelial growth factor (VEGF) and its receptors (Flt-1 and Flk-1) in esophageal squamous cell carcinoma. Anticancer Res (2003) 0.95
STAP-2/BKS, an adaptor/docking protein, modulates STAT3 activation in acute-phase response through its YXXQ motif. J Biol Chem (2003) 0.94
Green tea polyphenol-induced epidermal keratinocyte differentiation is associated with coordinated expression of p57/KIP2 and caspase 14. J Pharmacol Exp Ther (2004) 0.94
Thr-774 (transmembrane segment M5), Val-920 (M8), and Glu-954 (M9) are involved in Na+ transport, and Gln-923 (M8) is essential for Na,K-ATPase activity. J Biol Chem (2005) 0.93
Phase-noise characteristics of a 25-GHz-spaced optical frequency comb based on a phase- and intensity-modulated laser. Opt Express (2013) 0.93
Oral administration of lactoferrin increases NK cell activity in mice via increased production of IL-18 and type I IFN in the small intestine. J Interferon Cytokine Res (2006) 0.93
Association of serum glycated albumin to haemoglobin A1C ratio with hepatic function tests in patients with chronic liver disease. Ann Clin Biochem (2009) 0.93
Detection of retinal nerve fiber layer defects on retinal fundus images for early diagnosis of glaucoma. J Biomed Opt (2010) 0.93
Effectiveness of FDG-PET in screening of synchronous cancer of other organs in patients with esophageal cancer. Anticancer Res (2014) 0.93
Serum interleukin-12 and interleukin-18 levels as a tumor marker in patients with esophageal carcinoma. Cancer Lett (2004) 0.93
Allopurinol reduces neointimal hyperplasia in the carotid artery ligation model in spontaneously hypertensive rats. Hypertens Res (2006) 0.92
The clinical characteristics of sudden cardiac arrest in asymptomatic patients with congenital heart disease. Heart Vessels (2013) 0.92
Myopia and advanced-stage open-angle glaucoma. Ophthalmology (2002) 0.92
A new proliferation marker, minichromosome maintenance protein 2, is associated with tumor aggressiveness in esophageal squamous cell carcinoma. J Surg Oncol (2003) 0.92
Correlation of 18-F-fluorodeoxyglucose (FDG) accumulation with glucose transporter (Glut-1) expression in esophageal squamous cell carcinoma. Anticancer Res (2003) 0.92
Navigation-guided endoscopic biopsy for intraparenchymal brain tumor. Neurol Med Chir (Tokyo) (2011) 0.92
Association of urine acidification with visceral obesity and the metabolic syndrome. Endocr J (2011) 0.92
Ionizing irradiation induces apoptotic damage of salivary gland acinar cells via NADPH oxidase 1-dependent superoxide generation. Biochem Biophys Res Commun (2007) 0.92
Low peripheral lymphocyte count before focal radiotherapy plus concomitant temozolomide predicts severe lymphopenia during malignant glioma treatment. Neurol Med Chir (Tokyo) (2010) 0.92