Hong-Jian Zhu

Author PubWeight™ 38.25‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha. Cell 2002 4.92
2 Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model. J Am Soc Nephrol 2003 2.24
3 Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling. Nat Med 2005 2.06
4 Advanced glycation end products activate Smad signaling via TGF-beta-dependent and independent mechanisms: implications for diabetic renal and vascular disease. FASEB J 2003 1.93
5 Smad7 inhibits fibrotic effect of TGF-Beta on renal tubular epithelial cells by blocking Smad2 activation. J Am Soc Nephrol 2002 1.86
6 Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos. Mol Cell Biol 2003 1.59
7 Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components. Proteomics 2013 1.46
8 CR1/CR2 interactions modulate the functions of the cell surface epidermal growth factor receptor. J Biol Chem 2004 1.45
9 SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer. Cancer Res 2012 1.39
10 Role of TGF-beta signaling in extracellular matrix production under high glucose conditions. Kidney Int 2003 1.29
11 The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR. Oncogene 2004 1.28
12 Oncogenic H-ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. Mol Cell Proteomics 2013 1.04
13 Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes. Electrophoresis 2008 1.00
14 Secretome-based proteomic profiling of Ras-transformed MDCK cells reveals extracellular modulators of epithelial-mesenchymal transition. J Proteome Res 2009 0.99
15 Extracellular vesicle isolation and characterization: toward clinical application. J Clin Invest 2016 0.95
16 Proteomics profiling of Madin-Darby canine kidney plasma membranes reveals Wnt-5a involvement during oncogenic H-Ras/TGF-beta-mediated epithelial-mesenchymal transition. Mol Cell Proteomics 2010 0.94
17 Extracellular remodelling during oncogenic Ras-induced epithelial-mesenchymal transition facilitates MDCK cell migration. J Proteome Res 2010 0.94
18 Regulation and function of protein kinases and phosphatases. Enzyme Res 2011 0.94
19 TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers. Mol Cell Biol 2012 0.93
20 A novel non-catalytic mechanism employed by the C-terminal Src-homologous kinase to inhibit Src-family kinase activity. J Biol Chem 2004 0.86
21 PTEN catalysis of phospholipid dephosphorylation reaction follows a two-step mechanism in which the conserved aspartate-92 does not function as the general acid--mechanistic analysis of a familial Cowden disease-associated PTEN mutation. Cell Signal 2007 0.86
22 Perturbation of the CD4 T cell compartment and expansion of regulatory T cells in autoimmune-prone Lyn-deficient mice. J Immunol 2009 0.84
23 Transforming growth factor-beta (TGF-beta) and brain tumours. J Clin Neurosci 2008 0.84
24 Dynamin II function is required for EGF-mediated Stat3 activation but not Erk1/2 phosphorylation. Growth Factors 2012 0.82
25 The immune suppressive function of transforming growth factor-β (TGF-β) in human diseases. Growth Factors 2015 0.81
26 Tandem application of cationic colloidal silica and Triton X-114 for plasma membrane protein isolation and purification: towards developing an MDCK protein database. Proteomics 2011 0.81
27 Defining the substrate specificity determinants recognized by the active site of C-terminal Src kinase-homologous kinase (CHK) and identification of β-synuclein as a potential CHK physiological substrate. Biochemistry 2011 0.81
28 New reagents for improved in vitro and in vivo examination of TGF-β signalling. Growth Factors 2011 0.81
29 Analysis of Ras-induced oncogenic transformation of NIH-3T3 cells using differential-display 2-DE proteomics. Electrophoresis 2007 0.78
30 Unique biochemical properties of the protein tyrosine phosphatase activity of PTEN-demonstration of different active site structural requirements for phosphopeptide and phospholipid phosphatase activities of PTEN. Biochim Biophys Acta 2010 0.77
31 Expression, generation, and purification of unphosphorylated and phospho-Ser-380/Thr-382/Thr-383 form of recombinant PTEN phosphatase. Protein Expr Purif 2007 0.76
32 Genome sequence of a novel endornavirus from the phytopathogenic fungus Alternaria brassicicola. Arch Virol 2015 0.75
33 Complete genome sequence and organization of a novel virus from the rice false smut fungus Ustilaginoidea virens. Virus Genes 2014 0.75