Published in Enzyme Res on December 13, 2011
The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation. Cell Host Microbe (2013) 2.71
Profiling global kinome signatures of the radioresistant MCF-7/C6 breast cancer cells using MRM-based targeted proteomics. J Proteome Res (2014) 0.82
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Insulin induces phosphorylation of serine residues of translationally controlled tumor protein in 293T cells. Int J Mol Sci (2015) 0.76
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The low affinity glucose transporter HxtB is also involved in glucose signalling and metabolism in Aspergillus nidulans. Sci Rep (2017) 0.75
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Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs. Sci Signal (2010) 2.95
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Tuning bulk electrostatics to regulate protein function. Cell (2007) 1.85
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Probing protein-tyrosine phosphatase substrate specificity using a phosphotyrosine-containing phage library. J Biol Chem (2003) 1.05
Electrostatic effects in the control of glycogen phosphorylase by phosphorylation. Protein Sci (1994) 0.91
Predicting protein kinase specificity: Predikin update and performance in the DREAM4 challenge. PLoS One (2011) 0.90
Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha. Cell (2002) 4.92
Identification of a neuronal Cdk5 activator-binding protein as Cdk5 inhibitor. J Biol Chem (2002) 2.43
Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model. J Am Soc Nephrol (2003) 2.24
CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex. Mol Biol Cell (2007) 2.13
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CDK5RAP2 stimulates microtubule nucleation by the gamma-tubulin ring complex. J Cell Biol (2010) 1.80
Alpha2-chimaerin, cyclin-dependent Kinase 5/p35, and its target collapsin response mediator protein-2 are essential components in semaphorin 3A-induced growth-cone collapse. J Neurosci (2004) 1.66
Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos. Mol Cell Biol (2003) 1.59
Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components. Proteomics (2013) 1.46
CR1/CR2 interactions modulate the functions of the cell surface epidermal growth factor receptor. J Biol Chem (2004) 1.45
SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer. Cancer Res (2012) 1.39
A combined proteomics and metabolomics profiling of gastric cardia cancer reveals characteristic dysregulations in glucose metabolism. Mol Cell Proteomics (2010) 1.30
Role of TGF-beta signaling in extracellular matrix production under high glucose conditions. Kidney Int (2003) 1.29
The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR. Oncogene (2004) 1.28
Conserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complex. J Biol Chem (2010) 1.24
Specific inhibition of cyclin-dependent kinases and cell proliferation by harmine. Biochem Biophys Res Commun (2004) 1.17
Interaction of CDK5RAP2 with EB1 to track growing microtubule tips and to regulate microtubule dynamics. Mol Biol Cell (2009) 1.16
Whole-genome screening identifies proteins localized to distinct nuclear bodies. J Cell Biol (2013) 1.15
Anxa2 plays a critical role in enhanced invasiveness of the multidrug resistant human breast cancer cells. J Proteome Res (2009) 1.15
Leptin contributes to the adaptive responses of mice to high-fat diet intake through suppressing the lipogenic pathway. PLoS One (2009) 1.10
Identification of nuclear import mechanisms for the neuronal Cdk5 activator. J Biol Chem (2006) 1.08
Oncogenic H-ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. Mol Cell Proteomics (2013) 1.04
Microtubule association of the neuronal p35 activator of Cdk5. J Biol Chem (2007) 1.03
The protein SET binds the neuronal Cdk5 activator p35nck5a and modulates Cdk5/p35nck5a activity. J Biol Chem (2001) 1.02
Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes. Electrophoresis (2008) 1.00
Proteasome inhibition by lactacystin in primary neuronal cells induces both potentially neuroprotective and pro-apoptotic transcriptional responses: a microarray analysis. J Neurochem (2005) 0.99
Secretome-based proteomic profiling of Ras-transformed MDCK cells reveals extracellular modulators of epithelial-mesenchymal transition. J Proteome Res (2009) 0.99
Extracellular vesicle isolation and characterization: toward clinical application. J Clin Invest (2016) 0.95
Proteomics profiling of Madin-Darby canine kidney plasma membranes reveals Wnt-5a involvement during oncogenic H-Ras/TGF-beta-mediated epithelial-mesenchymal transition. Mol Cell Proteomics (2010) 0.94
Extracellular remodelling during oncogenic Ras-induced epithelial-mesenchymal transition facilitates MDCK cell migration. J Proteome Res (2010) 0.94
GATA2 as a potential metastasis-driving gene in prostate cancer. Oncotarget (2014) 0.94
TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers. Mol Cell Biol (2012) 0.93
Regulation of s6 kinase 1 activation by phosphorylation at ser-411. J Biol Chem (2007) 0.89
Protein-protein interactions in Cdk5 regulation and function. Neurosignals (2003) 0.88
Calmodulin binding and Cdk5 phosphorylation of p35 regulate its effect on microtubules. J Biol Chem (2008) 0.88
Cyclin-dependent kinases in neural development and degeneration. J Alzheimers Dis (2003) 0.88
Direct regulation of microtubule dynamics by protein kinase CK2. J Biol Chem (2003) 0.88
Frequent decreased expression of candidate tumor suppressor gene, DEC1, and its anchorage-independent growth properties and impact on global gene expression in esophageal carcinoma. Int J Cancer (2008) 0.87
Chronic exposure to U18666A induces apoptosis in cultured murine cortical neurons. Biochem Biophys Res Commun (2004) 0.87
The neuronal p35 activator of Cdk5 is a novel F-actin binding and bundling protein. Cell Mol Life Sci (2010) 0.86
A novel non-catalytic mechanism employed by the C-terminal Src-homologous kinase to inhibit Src-family kinase activity. J Biol Chem (2004) 0.86
Perturbation of the CD4 T cell compartment and expansion of regulatory T cells in autoimmune-prone Lyn-deficient mice. J Immunol (2009) 0.84
Transforming growth factor-beta (TGF-beta) and brain tumours. J Clin Neurosci (2008) 0.84
U18666A-mediated apoptosis in cultured murine cortical neurons: role of caspases, calpains and kinases. Cell Signal (2006) 0.83
Dynamin II function is required for EGF-mediated Stat3 activation but not Erk1/2 phosphorylation. Growth Factors (2012) 0.82
Hypochlorous acid induces apoptosis of cultured cortical neurons through activation of calpains and rupture of lysosomes. J Neurochem (2006) 0.82
The immune suppressive function of transforming growth factor-β (TGF-β) in human diseases. Growth Factors (2015) 0.81
Tandem application of cationic colloidal silica and Triton X-114 for plasma membrane protein isolation and purification: towards developing an MDCK protein database. Proteomics (2011) 0.81
New reagents for improved in vitro and in vivo examination of TGF-β signalling. Growth Factors (2011) 0.81
Defining the substrate specificity determinants recognized by the active site of C-terminal Src kinase-homologous kinase (CHK) and identification of β-synuclein as a potential CHK physiological substrate. Biochemistry (2011) 0.81
Dynamic recruitment of CDK5RAP2 to centrosomes requires its association with dynein. PLoS One (2013) 0.81
Phosphorylation of prion protein at serine 43 induces prion protein conformational change. J Neurosci (2009) 0.80
Signaling via a novel integral plasma membrane pool of a serine/threonine protein kinase PRK1 in mammalian cells. FASEB J (2004) 0.80
Neuronal apoptosis mediated by inhibition of intracellular cholesterol transport: microarray and proteomics analyses in cultured murine cortical neurons. J Cell Physiol (2007) 0.80
Analysis of Ras-induced oncogenic transformation of NIH-3T3 cells using differential-display 2-DE proteomics. Electrophoresis (2007) 0.78
Identification of p10 as a neurotoxic product generated from the proteolytic cleavage of the neuronal Cdk5 activator. J Cell Biochem (2010) 0.78
CD157 undergoes ligand-independent dimerization and colocalizes with caveolin in CHO and MCA102 fibroblasts. Cell Signal (2002) 0.78
Unique biochemical properties of the protein tyrosine phosphatase activity of PTEN-demonstration of different active site structural requirements for phosphopeptide and phospholipid phosphatase activities of PTEN. Biochim Biophys Acta (2010) 0.77
Optimization-based peptide mass fingerprinting for protein mixture identification. J Comput Biol (2010) 0.77
Discovery of stage-related proteins in esophageal squamous cell carcinoma using proteomic analysis. Proteomics Clin Appl (2007) 0.77
Protein kinase CK2 is an inhibitor of the neuronal Cdk5 kinase. J Biol Chem (2004) 0.77
[Investigation of discrepant proteins between two breast cancer cell lines with different metastatic abilities]. Ai Zheng (2006) 0.76
Expression, generation, and purification of unphosphorylated and phospho-Ser-380/Thr-382/Thr-383 form of recombinant PTEN phosphatase. Protein Expr Purif (2007) 0.76
Transcriptional insights on the regenerative mechanics of axotomized neurons in vitro. J Cell Mol Med (2012) 0.75
Bioinformatic analysis of data generated from MALDI mass spectrometry for biomarker discovery. Top Curr Chem (2013) 0.75
Genome sequence of a novel endornavirus from the phytopathogenic fungus Alternaria brassicicola. Arch Virol (2015) 0.75
Complete genome sequence and organization of a novel virus from the rice false smut fungus Ustilaginoidea virens. Virus Genes (2014) 0.75