Published in Biochim Biophys Acta on May 27, 2010
Genomic Rearrangements of PTEN in Prostate Cancer. Front Oncol (2013) 1.07
Structural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancer. Proteins (2016) 0.75
Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha. Cell (2002) 4.92
Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer. Clin Cancer Res (2009) 4.47
Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model. J Am Soc Nephrol (2003) 2.24
Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling. Nat Med (2005) 2.06
Quantitative selection of DNA aptamers through microfluidic selection and high-throughput sequencing. Proc Natl Acad Sci U S A (2010) 2.01
C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1. Hum Mol Genet (2006) 1.97
Advanced glycation end products activate Smad signaling via TGF-beta-dependent and independent mechanisms: implications for diabetic renal and vascular disease. FASEB J (2003) 1.93
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Micromagnetic selection of aptamers in microfluidic channels. Proc Natl Acad Sci U S A (2009) 1.66
Aptamer-functionalized Au nanoparticles for the amplified optical detection of thrombin. J Am Chem Soc (2004) 1.64
Continuous, real-time monitoring of cocaine in undiluted blood serum via a microfluidic, electrochemical aptamer-based sensor. J Am Chem Soc (2009) 1.63
Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos. Mol Cell Biol (2003) 1.59
Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components. Proteomics (2013) 1.46
CR1/CR2 interactions modulate the functions of the cell surface epidermal growth factor receptor. J Biol Chem (2004) 1.45
Endogenous and synthetic inhibitors of the Src-family protein tyrosine kinases. Biochim Biophys Acta (2005) 1.42
Optimization of electrochemical aptamer-based sensors via optimization of probe packing density and surface chemistry. Langmuir (2008) 1.40
Community-wide assessment of protein-interface modeling suggests improvements to design methodology. J Mol Biol (2011) 1.40
SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer. Cancer Res (2012) 1.39
High specificity, electrochemical sandwich assays based on single aptamer sequences and suitable for the direct detection of small-molecule targets in blood and other complex matrices. J Am Chem Soc (2009) 1.38
Identification and characterization of catabolic para-nitrophenol 4-monooxygenase and para-benzoquinone reductase from Pseudomonas sp. strain WBC-3. J Bacteriol (2009) 1.37
Role of TGF-beta signaling in extracellular matrix production under high glucose conditions. Kidney Int (2003) 1.29
The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR. Oncogene (2004) 1.28
Colorimetric detection of DNA, small molecules, proteins, and ions using unmodified gold nanoparticles and conjugated polyelectrolytes. Proc Natl Acad Sci U S A (2010) 1.27
Generation of highly specific aptamers via micromagnetic selection. Anal Chem (2009) 1.24
Exploring the parameter space of the coarse-grained UNRES force field by random search: selecting a transferable medium-resolution force field. J Comput Chem (2009) 1.22
Cerebrospinal fluid concentrations of gefitinib in patients with lung adenocarcinoma. Clin Lung Cancer (2012) 1.21
A ratiometric fluorescent probe based on FRET for imaging Hg2+ ions in living cells. Angew Chem Int Ed Engl (2008) 1.21
Chinese guidelines for the secondary prevention of ischemic stroke and transient ischemic attack 2010. CNS Neurosci Ther (2012) 1.20
Community-wide evaluation of methods for predicting the effect of mutations on protein-protein interactions. Proteins (2013) 1.20
"Alive" dyes as fluorescent sensors: fluorophore, mechanism, receptor and images in living cells. Chem Commun (Camb) (2010) 1.19
Biochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1). J Neurochem (2008) 1.18
C-terminal Src kinase (CSK) and CSK-homologous kinase (CHK)--endogenous negative regulators of Src-family protein kinases. Growth Factors (2005) 1.18
Increased arylhydrocarbon receptor expression offers a potential therapeutic target for pancreatic cancer. Oncogene (2002) 1.15
Probing the limits of aptamer affinity with a microfluidic SELEX platform. PLoS One (2011) 1.14
Piwil2 expressed in various stages of cervical neoplasia is a potential complementary marker for p16. Am J Transl Res (2010) 1.13
TSC1/2 signaling complex is essential for peripheral naïve CD8+ T cell survival and homeostasis in mice. PLoS One (2012) 1.12
Automated and fast building of three-dimensional RNA structures. Sci Rep (2012) 1.10
Genetic analysis of H1N1 influenza virus from throat swab samples in a microfluidic system for point-of-care diagnostics. J Am Chem Soc (2011) 1.09
Phase I trial of icotinib, a novel epidermal growth factor receptor tyrosine kinase inhibitor, in Chinese patients with non-small cell lung cancer. Chin Med J (Engl) (2011) 1.07
Oncogenic H-ras reprograms Madin-Darby canine kidney (MDCK) cell-derived exosomal proteins following epithelial-mesenchymal transition. Mol Cell Proteomics (2013) 1.04
Optimization of a reusable, DNA pseudoknot-based electrochemical sensor for sequence-specific DNA detection in blood serum. Anal Chem (2009) 1.03
ERalpha suppresses slug expression directly by transcriptional repression. Biochem J (2008) 1.03
Derivation and validation of a prediction rule for estimating advanced colorectal neoplasm risk in average-risk Chinese. Am J Epidemiol (2012) 1.02
Process-based network decomposition reveals backbone motif structure. Proc Natl Acad Sci U S A (2010) 1.01
Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes. Electrophoresis (2008) 1.00
In vitro selection of structure-switching, self-reporting aptamers. Proc Natl Acad Sci U S A (2010) 0.99
Secretome-based proteomic profiling of Ras-transformed MDCK cells reveals extracellular modulators of epithelial-mesenchymal transition. J Proteome Res (2009) 0.99
Amplified chemiluminescence surface detection of DNA and telomerase activity using catalytic nucleic acid labels. Anal Chem (2004) 0.98
Central metabolic responses to the overproduction of fatty acids in Escherichia coli based on 13C-metabolic flux analysis. Biotechnol Bioeng (2014) 0.97
Selection of phage-displayed peptides on live adherent cells in microfluidic channels. Proc Natl Acad Sci U S A (2011) 0.97
Characterization of a para-nitrophenol catabolic cluster in Pseudomonas sp. strain NyZ402 and construction of an engineered strain capable of simultaneously mineralizing both para- and ortho-nitrophenols. Biodegradation (2010) 0.97
Sensitive and selective amplified fluorescence DNA detection based on exonuclease III-aided target recycling. J Am Chem Soc (2010) 0.96
Detection of proteins in serum by micromagnetic aptamer PCR (MAP) technology. Angew Chem Int Ed Engl (2010) 0.96
Metabolic engineering of Synechocystis sp. strain PCC 6803 for isobutanol production. Appl Environ Microbiol (2012) 0.96
An electrochemical supersandwich assay for sensitive and selective DNA detection in complex matrices. J Am Chem Soc (2010) 0.96
Extracellular vesicle isolation and characterization: toward clinical application. J Clin Invest (2016) 0.95
Isomeric boron-fluorine complexes with donor-acceptor architecture: strong solid/liquid fluorescence and large Stokes shift. Org Lett (2008) 0.95
[A multicentre retrospective study of pulmonary mycosis clinically proven from 1998 to 2007]. Zhonghua Jie He He Hu Xi Za Zhi (2011) 0.95
Activatable rotor for quantifying lysosomal viscosity in living cells. J Am Chem Soc (2013) 0.95
Proteomics profiling of Madin-Darby canine kidney plasma membranes reveals Wnt-5a involvement during oncogenic H-Ras/TGF-beta-mediated epithelial-mesenchymal transition. Mol Cell Proteomics (2010) 0.94
Ratiometric and selective fluorescent sensor for CuII based on internal charge transfer (ICT). Org Lett (2005) 0.94
Extracellular remodelling during oncogenic Ras-induced epithelial-mesenchymal transition facilitates MDCK cell migration. J Proteome Res (2010) 0.94
Regulation and function of protein kinases and phosphatases. Enzyme Res (2011) 0.94
TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers. Mol Cell Biol (2012) 0.93
A novel protocol for three-dimensional structure prediction of RNA-protein complexes. Sci Rep (2013) 0.93
RNA stability under different combinations of amber force fields and solvation models. J Biomol Struct Dyn (2010) 0.92
Inhibition of expression of the chromatin remodeling gene, SNF2L, selectively leads to DNA damage, growth inhibition, and cancer cell death. Mol Cancer Res (2009) 0.91
Characterization of gene mutations and phenotypes of cystic fibrosis in Chinese patients. Respirology (2015) 0.91
Concomitant targeting of tumor cells and induction of T-cell response synergizes to effectively inhibit trastuzumab-resistant breast cancer. Cancer Res (2012) 0.90
ASPDock: protein-protein docking algorithm using atomic solvation parameters model. BMC Bioinformatics (2011) 0.90
C-terminal Src kinase-homologous kinase (CHK), a unique inhibitor inactivating multiple active conformations of Src family tyrosine kinases. J Biol Chem (2006) 0.90
Long-wavelength, photostable, two-photon excitable BODIPY fluorophores readily modifiable for molecular probes. J Org Chem (2013) 0.89
Identification of functional domains in Arabidopsis thaliana mRNA decapping enzyme (AtDcp2). Nucleic Acids Res (2007) 0.89
A lysosome-targetable and two-photon fluorescent probe for monitoring endogenous and exogenous nitric oxide in living cells. J Am Chem Soc (2012) 0.89
A new prodrug-derived ratiometric fluorescent probe for hypoxia: high selectivity of nitroreductase and imaging in tumor cell. Org Lett (2011) 0.88
Clinical outcome of neoadjuvant chemoradiation therapy with oxaliplatin and capecitabine or 5-fluorouracil for locally advanced rectal cancer. J Surg Oncol (2013) 0.88
On the binding of cationic, water-soluble conjugated polymers to DNA: electrostatic and hydrophobic interactions. J Am Chem Soc (2010) 0.87
Negative feedback regulation of fatty acid production based on a malonyl-CoA sensor-actuator. ACS Synth Biol (2014) 0.87
Targeting activation-induced cytidine deaminase overcomes tumor evasion of immunotherapy by CTLs. J Immunol (2010) 0.87
Selection is more intelligent than design: improving the affinity of a bivalent ligand through directed evolution. Nucleic Acids Res (2012) 0.87
Tumor gene mutations and messenger RNA expression: correlation with clinical response to icotinib hydrochloride in non-small cell lung cancer. Chin Med J (Engl) (2011) 0.87
[An investigation of the relationship between Lepr gene Gln223Arg polymorphism and obstructive sleep apnea hypopnea syndrome]. Zhonghua Jie He He Hu Xi Za Zhi (2003) 0.87
The protein folding network indicates that the ultrafast folding mutant of villin headpiece subdomain has a deeper folding funnel. J Chem Phys (2011) 0.87
Breast carcinomatous tumoral emboli can result from encircling lymphovasculogenesis rather than lymphovascular invasion. Oncotarget (2010) 0.87
i-Motif quadruplex DNA-based biosensor for distinguishing single- and multiwalled carbon nanotubes. J Am Chem Soc (2009) 0.86
A novel non-catalytic mechanism employed by the C-terminal Src-homologous kinase to inhibit Src-family kinase activity. J Biol Chem (2004) 0.86
Disruption of TSC1/2 signaling complex reveals a checkpoint governing thymic CD4+ CD25+ Foxp3+ regulatory T-cell development in mice. FASEB J (2013) 0.86
Effects of mutation, truncation, and temperature on the folding kinetics of a WW domain. J Mol Biol (2012) 0.86
A phase II study of neoadjuvant chemoradiotherapy with oxaliplatin and capecitabine for rectal cancer. Cancer Lett (2011) 0.86
Structural elements and allosteric mechanisms governing regulation and catalysis of CSK-family kinases and their inhibition of Src-family kinases. Growth Factors (2010) 0.85
Human cytochrome P450 4F11: heterologous expression in bacteria, purification, and characterization of catalytic function. Arch Biochem Biophys (2009) 0.85
Improvements of the hierarchical approach for predicting RNA tertiary structure. J Biomol Struct Dyn (2011) 0.85
Measurement of aptamer-protein interactions with back-scattering interferometry. Anal Chem (2011) 0.85
Inhibition of the acetycholine esterase-stimulated growth of Au nanoparticles: nanotechnology-based sensing of nerve gases. Nano Lett (2005) 0.85
A photostable near-infrared fluorescent tracker with pH-independent specificity to lysosomes for long time and multicolor imaging. ACS Appl Mater Interfaces (2014) 0.84
Transforming growth factor-beta (TGF-beta) and brain tumours. J Clin Neurosci (2008) 0.84