Published in J Biol Chem on June 04, 2003
Interactions between heparan sulfate and proteins: the concept of specificity. J Cell Biol (2006) 3.49
Heparan sulfate proteoglycans. Cold Spring Harb Perspect Biol (2011) 2.96
Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development. Genes Dev (2007) 1.68
Newly generated heparanase knock-out mice unravel co-regulation of heparanase and matrix metalloproteinases. PLoS One (2009) 1.46
Disruption of glomerular basement membrane charge through podocyte-specific mutation of agrin does not alter glomerular permselectivity. Am J Pathol (2007) 1.43
Sulfation pattern in glycosaminoglycan: does it have a code? Glycoconj J (2004) 1.43
In vivo fragmentation of heparan sulfate by heparanase overexpression renders mice resistant to amyloid protein A amyloidosis. Proc Natl Acad Sci U S A (2005) 1.37
Lacrimal gland development and Fgf10-Fgfr2b signaling are controlled by 2-O- and 6-O-sulfated heparan sulfate. J Biol Chem (2011) 1.19
Heparan sulfate proteoglycan syndecan-3 is a novel receptor for GDNF, neurturin, and artemin. J Cell Biol (2011) 1.18
Fibroblast growth factors share binding sites in heparan sulphate. Biochem J (2005) 1.15
An introduction to proteoglycans and their localization. J Histochem Cytochem (2012) 1.08
Lack of L-iduronic acid in heparan sulfate affects interaction with growth factors and cell signaling. J Biol Chem (2009) 1.07
Heparan sulfate domain organization and sulfation modulate FGF-induced cell signaling. J Biol Chem (2010) 1.06
Dermatan sulfate epimerase 1-deficient mice have reduced content and changed distribution of iduronic acids in dermatan sulfate and an altered collagen structure in skin. Mol Cell Biol (2009) 1.05
Genetic analysis of the heparan modification network in Caenorhabditis elegans. J Biol Chem (2011) 1.05
Endothelial heparan sulfate in angiogenesis. Prog Mol Biol Transl Sci (2010) 1.02
Quantitative trait loci, genes, and polymorphisms that regulate bone mineral density in mouse. Genomics (2009) 0.96
Impairment of glycosaminoglycan synthesis in mucopolysaccharidosis type IIIA cells by using siRNA: a potential therapeutic approach for Sanfilippo disease. Eur J Hum Genet (2009) 0.96
Using engineered 2-O-sulfotransferase to determine the activity of heparan sulfate C5-epimerase and its mutants. J Biol Chem (2010) 0.95
Hs2st mediated kidney mesenchyme induction regulates early ureteric bud branching. Dev Biol (2010) 0.94
Truncation of the catalytic domain of the cylindromatosis tumor suppressor impairs lung maturation. Neoplasia (2009) 0.94
Stage-dependent regulation of mammary ductal branching by heparan sulfate and HGF-cMet signaling. Dev Biol (2011) 0.93
Enzymatic modifications of exopolysaccharides enhance bacterial persistence. Front Microbiol (2015) 0.91
Loss of the heparan sulfate sulfotransferase, Ndst1, in mammary epithelial cells selectively blocks lobuloalveolar development in mice. PLoS One (2010) 0.90
D-glucuronyl C5-epimerase suppresses small-cell lung cancer cell proliferation in vitro and tumour growth in vivo. Br J Cancer (2011) 0.89
Antiproliferative effect of D-glucuronyl C5-epimerase in human breast cancer cells. Cancer Cell Int (2010) 0.89
In vivo manipulation of heparan sulfate structure and its effect on Drosophila development. Glycobiology (2010) 0.87
D-glucuronyl C5-epimerase acts in dorso-ventral axis formation in zebrafish. BMC Dev Biol (2005) 0.86
Sulfatase 1 is an inhibitor of ductal morphogenesis with sexually dimorphic expression in the urogenital sinus. Endocrinology (2010) 0.86
The glomerular basement membrane as a model system to study the bioactivity of heparan sulfate glycosaminoglycans. Microsc Microanal (2012) 0.86
Hydrogen/deuterium exchange-LC-MS approach to characterize the action of heparan sulfate C5-epimerase. Anal Bioanal Chem (2011) 0.85
The human D-glucuronyl C5-epimerase gene is transcriptionally activated through the beta-catenin-TCF4 pathway. Biochem J (2005) 0.85
The 3'-phosphoadenosine 5'-phosphosulfate transporters, PAPST1 and 2, contribute to the maintenance and differentiation of mouse embryonic stem cells. PLoS One (2009) 0.85
Human genetic disorders and knockout mice deficient in glycosaminoglycan. Biomed Res Int (2014) 0.85
Novel 'phage display antibodies identify distinct heparan sulfate domains in developing mammalian lung. Pediatr Surg Int (2007) 0.84
Glucuronic acid epimerase is associated with plasma triglyceride and high-density lipoprotein cholesterol levels in Turks. Ann Hum Genet (2011) 0.83
Amino acid substitutions in the E2 glycoprotein of Sindbis-like virus XJ-160 confer the ability to undergo heparan sulfate-dependent infection of mouse embryonic fibroblasts. Virol J (2010) 0.82
Structure and epitope distribution of heparan sulfate is disrupted in experimental lung hypoplasia: a glycobiological epigenetic cause for malformation? BMC Dev Biol (2011) 0.82
Heparan Sulfate in the Developing, Healthy, and Injured Lung. Am J Respir Cell Mol Biol (2016) 0.82
The TCF4/β-catenin pathway and chromatin structure cooperate to regulate D-glucuronyl C5-epimerase expression in breast cancer. Epigenetics (2012) 0.81
The Extracellular Matrix in Bronchopulmonary Dysplasia: Target and Source. Front Med (Lausanne) (2015) 0.81
The mechanisms and physiological relevance of glycocalyx degradation in hepatic ischemia/reperfusion injury. Antioxid Redox Signal (2014) 0.81
Similarity of recombinant human perlecan domain 1 by alternative expression systems bioactive heterogenous recombinant human perlecan D1. BMC Biotechnol (2010) 0.81
Combinatorial roles of heparan sulfate proteoglycans and heparan sulfates in Caenorhabditis elegans neural development. PLoS One (2014) 0.81
Changes in expression of proteoglycan core proteins and heparan sulfate enzymes in the developing and adult murine aorta. J Cardiovasc Transl Res (2011) 0.81
Analysis of Drosophila glucuronyl C5-epimerase: implications for developmental roles of heparan sulfate sulfation compensation and 2-O-sulfated glucuronic acid. J Biol Chem (2013) 0.80
Heterogeneity of d-glucuronyl C5-epimerase expression and epigenetic regulation in prostate cancer. Cancer Med (2013) 0.80
N-sulfation of heparan sulfate regulates early branching events in the developing mammary gland. J Biol Chem (2012) 0.80
Heparan sulfate expression in the neural crest is essential for mouse cardiogenesis. Matrix Biol (2013) 0.80
Structural and functional study of D-glucuronyl C5-epimerase. J Biol Chem (2015) 0.79
Dermatan Sulfate-Free Mice Display Embryological Defects and Are Neonatal Lethal Despite Normal Lymphoid and Non-Lymphoid Organogenesis. PLoS One (2015) 0.79
Catalytic mechanism and mode of action of the periplasmic alginate epimerase AlgG. J Biol Chem (2014) 0.79
Growth factor-heparan sulfate "switches" regulating stages of branching morphogenesis. Pediatr Nephrol (2014) 0.79
The role of syndecan-1 in cellular signaling and its effects on heparan sulfate biosynthesis in mesenchymal tumors. Front Oncol (2013) 0.79
Molecular basis of cleft palates in mice. World J Biol Chem (2015) 0.78
A novel bacterial enzyme with D-glucuronyl C5-epimerase activity. J Biol Chem (2013) 0.78
Analysis of axon guidance defects at the optic chiasm in heparan sulphate sulphotransferase compound mutant mice. J Anat (2011) 0.78
Dermatan sulfate epimerase 1 deficient mice as a model for human abdominal wall defects. Birth Defects Res A Clin Mol Teratol (2014) 0.78
Glycosaminoglycans and infection. Front Biosci (Landmark Ed) (2016) 0.77
Heparan sulfate biosynthesis enzymes in embryonic stem cell biology. J Histochem Cytochem (2012) 0.76
Temporal and functional changes in glycosaminoglycan expression during osteogenesis. J Mol Histol (2007) 0.76
Quantitative trait loci for energy balance traits in an advanced intercross line derived from mice divergently selected for heat loss. PeerJ (2014) 0.75
Enzyme overexpression - an exercise toward understanding regulation of heparan sulfate biosynthesis. Sci Rep (2016) 0.75
The role of heparan sulphate in development: the ectodermal story. Int J Exp Pathol (2016) 0.75
The function of heparan sulfate during branching morphogenesis. Matrix Biol (2016) 0.75
Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis. BMC Bioinformatics (2010) 7.78
Genome-wide association study identifies 1p36.22 as a new susceptibility locus for hepatocellular carcinoma in chronic hepatitis B virus carriers. Nat Genet (2010) 4.01
Sofosbuvir and ribavirin for hepatitis C genotype 1 in patients with unfavorable treatment characteristics: a randomized clinical trial. JAMA (2013) 3.82
Interactions between heparan sulfate and proteins: the concept of specificity. J Cell Biol (2006) 3.49
QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling. J Cell Biol (2003) 2.88
Mast cells can enhance resistance to snake and honeybee venoms. Science (2006) 2.72
Preparation and evaluation of recombinant severe fever with thrombocytopenia syndrome virus nucleocapsid protein for detection of total antibodies in human and animal sera by double-antigen sandwich enzyme-linked immunosorbent assay. J Clin Microbiol (2011) 2.63
KRAB zinc finger proteins: an analysis of the molecular mechanisms governing their increase in numbers and complexity during evolution. Mol Biol Evol (2002) 2.27
Risk factors for ERCP-related complications: a prospective multicenter study. Am J Gastroenterol (2009) 2.12
Environmental chemical exposures and human epigenetics. Int J Epidemiol (2011) 1.97
The 5'-AMP-activated protein kinase gamma3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle. J Biol Chem (2004) 1.94
Photoluminescence emission and Raman response of monolayer MoS₂, MoSe₂, and WSe₂. Opt Express (2013) 1.92
Targeted disruption of the ribosomal protein S19 gene is lethal prior to implantation. Mol Cell Biol (2004) 1.85
Kidney function, albuminuria, and all-cause mortality in the REGARDS (Reasons for Geographic and Racial Differences in Stroke) study. Am J Kidney Dis (2010) 1.71
Mast cell proteases. Adv Immunol (2007) 1.70
A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2. J Biol Chem (2004) 1.70
MicroRNA-193b represses cell proliferation and regulates cyclin D1 in melanoma. Am J Pathol (2010) 1.69
Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development. Genes Dev (2007) 1.68
Rab27b regulates number and secretion of platelet dense granules. Proc Natl Acad Sci U S A (2007) 1.66
Surface-exposed amino acid residues of HPV16 L1 protein mediating interaction with cell surface heparan sulfate. J Biol Chem (2007) 1.66
Transgenic expression of mammalian heparanase uncovers physiological functions of heparan sulfate in tissue morphogenesis, vascularization, and feeding behavior. FASEB J (2004) 1.64
Substrate specificity and domain functions of extracellular heparan sulfate 6-O-endosulfatases, QSulf1 and QSulf2. J Biol Chem (2005) 1.64
Effects of sugar inhibition on cellulases and beta-glucosidase during enzymatic hydrolysis of softwood substrates. Appl Biochem Biotechnol (2004) 1.58
Association of chronic kidney disease with atrial fibrillation among adults in the United States: REasons for Geographic and Racial Differences in Stroke (REGARDS) Study. Circ Arrhythm Electrophysiol (2010) 1.51
1976-1983, a critical period in the history of heparin: the discovery of the antithrombin binding site. Biochimie (2003) 1.50
The phosphate transporter gene OsPht1;8 is involved in phosphate homeostasis in rice. Plant Physiol (2011) 1.48
Newly generated heparanase knock-out mice unravel co-regulation of heparanase and matrix metalloproteinases. PLoS One (2009) 1.46
3-O-sulfated oligosaccharide structures are recognized by anti-heparan sulfate antibody HS4C3. J Biol Chem (2005) 1.43
Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation. Circulation (2009) 1.43
Heparanase overexpression reduces carrageenan-induced mechanical and cold hypersensitivity in mice. Neurosci Lett (2011) 1.41
Safety of infliximab therapy in rheumatoid arthritis patients with previous exposure to hepatitis B virus. Int J Rheum Dis (2013) 1.39
Hydrothermal syntheses and structural characterizations of organic-inorganic hybrid materials of the M(II)-ligand/vanadium oxide system (M(II) = Mn(II), Cu(II) and Zn(II); ligand = 2,2'-bipyridine and 1,10-phenanthroline). Dalton Trans (2007) 1.38
In vivo fragmentation of heparan sulfate by heparanase overexpression renders mice resistant to amyloid protein A amyloidosis. Proc Natl Acad Sci U S A (2005) 1.37
Heparan sulfate-related oligosaccharides in ternary complex formation with fibroblast growth factors 1 and 2 and their receptors. J Biol Chem (2006) 1.35
Surrogate tissue telomere length and cancer risk: shorter or longer? Cancer Lett (2012) 1.35
Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism. Proc Natl Acad Sci U S A (2009) 1.34
Heparan sulfate and development: differential roles of the N-acetylglucosamine N-deacetylase/N-sulfotransferase isozymes. Biochim Biophys Acta (2002) 1.34
Biorefining of softwoods using ethanol organosolv pulping: preliminary evaluation of process streams for manufacture of fuel-grade ethanol and co-products. Biotechnol Bioeng (2005) 1.30
Independent degeneration of photoreceptors and retinal pigment epithelium in conditional knockout mouse models of choroideremia. J Clin Invest (2006) 1.29
Airborne particulate matter and mitochondrial damage: a cross-sectional study. Environ Health (2010) 1.29
Downgrading recent estimates of land available for biofuel production. Environ Sci Technol (2013) 1.28
Heparin/heparan sulfate biosynthesis: processive formation of N-sulfated domains. J Biol Chem (2008) 1.27
Biosynthetic oligosaccharide libraries for identification of protein-binding heparan sulfate motifs. Exploring the structural diversity by screening for fibroblast growth factor (FGF)1 and FGF2 binding. J Biol Chem (2002) 1.27
Transgenic or tumor-induced expression of heparanase upregulates sulfation of heparan sulfate. Nat Chem Biol (2007) 1.25
Reproducibility of optical coherence tomography in multiple sclerosis. Arch Neurol (2008) 1.25
Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis. Nat Med (2008) 1.23
Land availability for biofuel production. Environ Sci Technol (2010) 1.23
Rab27b regulates mast cell granule dynamics and secretion. Traffic (2007) 1.22
The microRNA-200 family is upregulated in endometrial carcinoma. PLoS One (2011) 1.20
Super-stretchable, transparent carbon nanotube-based capacitive strain sensors for human motion detection. Sci Rep (2013) 1.19
A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23. Nat Genet (2013) 1.19
Neutrophil elastase depends on serglycin proteoglycan for localization in granules. Blood (2007) 1.16
Characterization of anti-heparan sulfate phage display antibodies AO4B08 and HS4E4. J Biol Chem (2007) 1.16
Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice. J Clin Invest (2011) 1.16
Multicolor microRNA FISH effectively differentiates tumor types. J Clin Invest (2013) 1.16
Success and complication rates of two precut techniques, transpancreatic sphincterotomy and needle-knife sphincterotomy for bile duct cannulation. J Gastrointest Surg (2010) 1.15
Fibroblast growth factors share binding sites in heparan sulphate. Biochem J (2005) 1.15
Mouse mast cell protease 4 is the major chymase in murine airways and has a protective role in allergic airway inflammation. J Immunol (2009) 1.15
Biosynthesis of dermatan sulfate: chondroitin-glucuronate C5-epimerase is identical to SART2. J Biol Chem (2006) 1.15
Scoring system for renal pathology in Fabry disease: report of the International Study Group of Fabry Nephropathy (ISGFN). Nephrol Dial Transplant (2009) 1.15
An upstream activation sequence controls the expression of AOX1 gene in Pichia pastoris. FEMS Yeast Res (2009) 1.14
Identification and characterization of a mammalian 14-kDa phosphohistidine phosphatase. Eur J Biochem (2002) 1.14
The αvβ6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells. J Clin Invest (2012) 1.13
High-throughput synthesis of single-layer MoS2 nanosheets as a near-infrared photothermal-triggered drug delivery for effective cancer therapy. ACS Nano (2014) 1.12
A binding site for highly sulfated heparan sulfate is identified in the N terminus of the circumsporozoite protein: significance for malarial sporozoite attachment to hepatocytes. J Biol Chem (2004) 1.12
Fluorescent metal-organic polymers of zinc and cadmium from hydrothermal in situ acylation reaction. Dalton Trans (2010) 1.11
Nitrocellulose filter binding to assess binding of glycosaminoglycans to proteins. Methods Enzymol (2003) 1.11
Structural basis for the neutralization and genotype specificity of hepatitis E virus. Proc Natl Acad Sci U S A (2011) 1.11
Ginsenoside Rd attenuates early oxidative damage and sequential inflammatory response after transient focal ischemia in rats. Neurochem Int (2010) 1.11
Expression of beta-amyloid induced age-dependent presynaptic and axonal changes in Drosophila. J Neurosci (2010) 1.10
Multiple kernel learning in protein-protein interaction extraction from biomedical literature. Artif Intell Med (2011) 1.10
Heparan sulfate C5-epimerase is essential for heparin biosynthesis in mast cells. Nat Chem Biol (2006) 1.10
Serglycin-deficient cytotoxic T lymphocytes display defective secretory granule maturation and granzyme B storage. J Biol Chem (2005) 1.09
Biosynthesis of hyaluronan: direction of chain elongation. J Biol Chem (2004) 1.09
Efficacy of entecavir treatment for up to 5 years in nucleos(t)ide-naïve chronic hepatitis B patients in real life. Int J Med Sci (2013) 1.09
miR-193b Regulates Mcl-1 in Melanoma. Am J Pathol (2011) 1.09
Air pollution exposure and telomere length in highly exposed subjects in Beijing, China: a repeated-measure study. Environ Int (2012) 1.08
Role of (1,3)(1,4)-β-glucan in cell walls: interaction with cellulose. Biomacromolecules (2014) 1.08
Role of heparan sulfate domain organization in endostatin inhibition of endothelial cell function. EMBO J (2002) 1.07
Laminin alpha1 globular domains 4-5 induce fetal development but are not vital for embryonic basement membrane assembly. Proc Natl Acad Sci U S A (2005) 1.07
Lack of L-iduronic acid in heparan sulfate affects interaction with growth factors and cell signaling. J Biol Chem (2009) 1.07
Serotonin and histamine storage in mast cell secretory granules is dependent on serglycin proteoglycan. J Allergy Clin Immunol (2008) 1.07
Intertwined aligned carbon nanotube fiber based dye-sensitized solar cells. Nano Lett (2012) 1.06
A constitutive expressed phosphate transporter, OsPht1;1, modulates phosphate uptake and translocation in phosphate-replete rice. Plant Physiol (2012) 1.06
Heparan sulfate domain organization and sulfation modulate FGF-induced cell signaling. J Biol Chem (2010) 1.06
Cooperation between mast cell carboxypeptidase A and the chymase mouse mast cell protease 4 in the formation and degradation of angiotensin II. J Biol Chem (2004) 1.05
Up-conversion cell imaging and pH-induced thermally controlled drug release from NaYF4/Yb3+/Er3+@hydrogel core-shell hybrid microspheres. ACS Nano (2012) 1.05
Effects of particulate air pollution on blood pressure in a highly exposed population in Beijing, China: a repeated-measure study. Environ Health (2011) 1.04
Heparan sulfate mediates amyloid-beta internalization and cytotoxicity. Glycobiology (2010) 1.04