A globin in the nucleus!

Neuroglobin: an endogenous neuroprotectant. Curr Opin Pharmacol (2007) 1.53

Effects of neuroglobin overexpression on mitochondrial function and oxidative stress following hypoxia/reoxygenation in cultured neurons. J Neurosci Res (2009) 1.25

Neuroglobin protects PC12 cells against oxidative stress. Brain Res (2007) 1.18

Reduced infarct size in neuroglobin-null mice after experimental stroke in vivo. Exp Transl Stroke Med (2012) 1.08

Neuroglobin protects PC12 cells against beta-amyloid-induced cell injury. Neurobiol Aging (2007) 1.08

Neuroglobin-overexpression alters hypoxic response gene expression in primary neuron culture following oxygen glucose deprivation. Neuroscience (2009) 1.04

Hemoglobin expression and regulation in glaucoma: insights into retinal ganglion cell oxygenation. Invest Ophthalmol Vis Sci (2009) 1.03

Neuroprotective roles and mechanisms of neuroglobin. Neurol Res (2009) 0.99

Neuroglobin-deficiency exacerbates Hif1A and c-FOS response, but does not affect neuronal survival during severe hypoxia in vivo. PLoS One (2011) 0.97

Neuroglobin protects neurons against oxidative stress in global ischemia. J Cereb Blood Flow Metab (2010) 0.96

Cytoglobin is a stress-responsive hemoprotein expressed in the developing and adult brain. J Histochem Cytochem (2006) 0.95

Neuroglobin, a novel target for endogenous neuroprotection against stroke and neurodegenerative disorders. Int J Mol Sci (2012) 0.94

Mechanisms of neuroprotection from hypoxia-ischemia (HI) brain injury by up-regulation of cytoglobin (CYGB) in a neonatal rat model. J Biol Chem (2013) 0.91

Electron transfer function versus oxygen delivery: a comparative study for several hexacoordinated globins across the animal kingdom. PLoS One (2011) 0.91

The heme environment of mouse neuroglobin: histidine imidazole plane orientations obtained from solution NMR and EPR spectroscopy as compared with X-ray crystallography. J Biol Inorg Chem (2006) 0.90

Cytoglobin modulates myogenic progenitor cell viability and muscle regeneration. Proc Natl Acad Sci U S A (2013) 0.87

Cytoglobin is expressed in hepatic stellate cells, but not in myofibroblasts, in normal and fibrotic human liver. Lab Invest (2013) 0.87

Human neuroglobin protein in cerebrospinal fluid. Proteome Sci (2005) 0.85

The anti-apoptotic role of neuroglobin. Cells (2012) 0.83

Globin-like proteins in Caenorhabditis elegans: in vivo localization, ligand binding and structural properties. BMC Biochem (2010) 0.82

Neuroglobin and cytoglobin distribution in the anterior eye segment: a comparative immunohistochemical study. J Histochem Cytochem (2008) 0.82

A gene-environment study of cytoglobin in the human and rat hippocampus. PLoS One (2013) 0.79

Neuroglobin Expression in the Mammalian Auditory System. Mol Neurobiol (2015) 0.79

Molecular dynamics simulation of a carboxy murine neuroglobin mutated on the proximal side: heme displacement and concomitant rearrangement in loop regions. J Mol Model (2009) 0.77

Melanoma transition is frequently accompanied by a loss of cytoglobin expression in melanocytes: a novel expression site of cytoglobin. PLoS One (2014) 0.77

Brain globins in physiology and pathology. Med Gas Res (2016) 0.76

Cytoglobin: a potential marker for adipogenic differentiation in preadipocytes in vitro. Cytotechnology (2016) 0.75

Genetic determinants of neuroglobin transcription. Neurogenetics (2013) 0.75

Intermediate Tyrosyl Radical and Amyloid Structure in Peroxide-Activated Cytoglobin. PLoS One (2015) 0.75

A distal ligand mutes the interaction of hydrogen sulfide with human neuroglobin. J Biol Chem (2017) 0.75

Oxygen binding and nitric oxide dioxygenase activity of cytoglobin are altered to different extents by cysteine modification. FEBS Open Bio (2017) 0.75

Impaired hypoxic tolerance in APP23 mice: a dysregulation of neuroprotective globin levels. FEBS Lett (2017) 0.75

The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity. J Clin Invest (2003) 4.11

T1DBase: integration and presentation of complex data for type 1 diabetes research. Nucleic Acids Res (2006) 3.25

Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis. Nat Med (2005) 2.83

Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung. Cancer Cell (2011) 2.63

Neuroglobin and cytoglobin. Fresh blood for the vertebrate globin family. EMBO Rep (2002) 2.50

High-dose folic acid pretreatment blunts cardiac dysfunction during ischemia coupled to maintenance of high-energy phosphates and reduces postreperfusion injury. Circulation (2008) 2.47

Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis. J Biol Chem (2006) 2.26

Reactivity studies of the Fe(III) and Fe(II)NO forms of human neuroglobin reveal a potential role against oxidative stress. J Biol Chem (2004) 1.83

Human brain neuroglobin structure reveals a distinct mode of controlling oxygen affinity. Structure (2003) 1.75

Neuroglobin and cytoglobin in search of their role in the vertebrate globin family. J Inorg Biochem (2005) 1.71

Evidence for a role of neuroepithelial bodies as complex airway sensors: comparison with smooth muscle-associated airway receptors. J Appl Physiol (1985) (2006) 1.66

In vitro susceptibilities of Leishmania donovani promastigote and amastigote stages to antileishmanial reference drugs: practical relevance of stage-specific differences. Antimicrob Agents Chemother (2009) 1.66

A phylogenomic profile of globins. BMC Evol Biol (2006) 1.64

Functional differentiation of myoglobin isoforms in hypoxia-tolerant carp indicates tissue-specific protective roles. Am J Physiol Regul Integr Comp Physiol (2011) 1.55

Detailed transcriptome atlas of the pancreatic beta cell. BMC Med Genomics (2009) 1.55

A decade of Raman spectroscopy in art and archaeology. Chem Rev (2007) 1.54

Dual sensory innervation of pulmonary neuroepithelial bodies. Am J Respir Cell Mol Biol (2003) 1.52

Systemic anti-vascular endothelial growth factor therapies induce a painful sensory neuropathy. Brain (2012) 1.52

Allosteric regulation and temperature dependence of oxygen binding in human neuroglobin and cytoglobin. Molecular mechanisms and physiological significance. J Biol Chem (2004) 1.51

Neuroglobin and cytoglobin overexpression protects human SH-SY5Y neuroblastoma cells against oxidative stress-induced cell death. Neurosci Lett (2006) 1.50

Functional live cell imaging of the pulmonary neuroepithelial body microenvironment. Am J Respir Cell Mol Biol (2008) 1.48

The redox state of the cell regulates the ligand binding affinity of human neuroglobin and cytoglobin. J Biol Chem (2003) 1.47

T1DBase, a community web-based resource for type 1 diabetes research. Nucleic Acids Res (2005) 1.44

Reactions of ferrous neuroglobin and cytoglobin with nitrite under anaerobic conditions. J Inorg Biochem (2008) 1.41

Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells. Diabetes (2009) 1.39

Nitric oxide binding properties of neuroglobin. A characterization by EPR and flash photolysis. J Biol Chem (2002) 1.34

Molecular diagnostics for congenital hearing loss including 15 deafness genes using a next generation sequencing platform. BMC Med Genomics (2012) 1.32

Selective clearance of macrophages in atherosclerotic plaques by autophagy. J Am Coll Cardiol (2007) 1.31

Involvement of PLEKHM1 in osteoclastic vesicular transport and osteopetrosis in incisors absent rats and humans. J Clin Invest (2007) 1.29

Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients. J Clin Endocrinol Metab (2011) 1.27

Glucose-regulated gene expression maintaining the glucose-responsive state of beta-cells. Diabetes (2002) 1.27

Wide diversity in structure and expression profiles among members of the Caenorhabditis elegans globin protein family. BMC Genomics (2007) 1.26

Diversity of globin function: enzymatic, transport, storage, and sensing. J Biol Chem (2008) 1.25

A model of globin evolution. Gene (2007) 1.22

Three globin lineages belonging to two structural classes in genomes from the three kingdoms of life. Proc Natl Acad Sci U S A (2005) 1.22

The reaction of neuroglobin with potential redox protein partners cytochrome b5 and cytochrome c. FEBS Lett (2006) 1.21

The WFS1 gene, responsible for low frequency sensorineural hearing loss and Wolfram syndrome, is expressed in a variety of inner ear cells. Histochem Cell Biol (2003) 1.17

Neuroglobin and cytoglobin expression in mice. Evidence for a correlation with reactive oxygen species scavenging. FEBS J (2007) 1.17

Anoxia or oxygen and glucose deprivation in SH-SY5Y cells: a step closer to the unraveling of neuroglobin and cytoglobin functions. Gene (2007) 1.15

Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways. Diabetes (2008) 1.14

Solution 1h NMR characterization of equilibrium heme orientational disorder with functional consequences in mouse neuroglobin. J Am Chem Soc (2003) 1.12

Crystal structure of cytoglobin: the fourth globin type discovered in man displays heme hexa-coordination. J Mol Biol (2004) 1.12

Heme-ligand tunneling in group I truncated hemoglobins. J Biol Chem (2004) 1.12

Small heat-shock protein HSPB1 mutants stabilize microtubules in Charcot-Marie-Tooth neuropathy. J Neurosci (2011) 1.12

Dense-core senile plaques in the Flemish variant of Alzheimer's disease are vasocentric. Am J Pathol (2002) 1.11

Review: correlations between oxygen affinity and sequence classifications of plant hemoglobins. Biopolymers (2009) 1.10

Importance of suitable reference gene selection for quantitative real-time PCR: special reference to mouse myocardial infarction studies. PLoS One (2011) 1.10

Disruption of the gamma-interferon signaling pathway at the level of signal transducer and activator of transcription-1 prevents immune destruction of beta-cells. Diabetes (2005) 1.09

The dissection course - necessary and indispensable for teaching anatomy to medical students. Ann Anat (2008) 1.08

Use of a systems biology approach to understand pancreatic beta-cell death in Type 1 diabetes. Biochem Soc Trans (2008) 1.08

Neuroglobin and other hexacoordinated hemoglobins show a weak temperature dependence of oxygen binding. Biophys J (2004) 1.08

Novel mechanism for high-altitude adaptation in hemoglobin of the Andean frog Telmatobius peruvianus. Am J Physiol Regul Integr Comp Physiol (2002) 1.07

Anatomical characterization of cytoglobin and neuroglobin mRNA and protein expression in the mouse brain. Brain Res (2010) 1.07

Neurochemical identification of enteric neurons expressing P2X(3) receptors in the guinea-pig ileum. Histochem Cell Biol (2002) 1.06

The Caenorhabditis globin gene family reveals extensive nematode-specific radiation and diversification. BMC Evol Biol (2008) 1.06

Automatic assessment of stent neointimal coverage by intravascular optical coherence tomography. Eur Heart J Cardiovasc Imaging (2013) 1.06

Proteomics analysis of cytokine-induced dysfunction and death in insulin-producing INS-1E cells: new insights into the pathways involved. Mol Cell Proteomics (2007) 1.05

Schistosomicidal activity of the antimalarial drug, mefloquine, in Schistosoma mansoni-infected mice. Travel Med Infect Dis (2008) 1.05

MRI visualization of endogenous neural progenitor cell migration along the RMS in the adult mouse brain: validation of various MPIO labeling strategies. Neuroimage (2009) 1.04

Role of furin in granular acidification in the endocrine pancreas: identification of the V-ATPase subunit Ac45 as a candidate substrate. Proc Natl Acad Sci U S A (2008) 1.03

Androglobin: a chimeric globin in metazoans that is preferentially expressed in Mammalian testes. Mol Biol Evol (2011) 1.02

Intrinsic choroidal neurons in the human eye: projections, targets, and basic electrophysiological data. Invest Ophthalmol Vis Sci (2003) 1.02

Immunohistochemical analysis of macroautophagy: recommendations and limitations. Autophagy (2012) 1.02

Functional morphology of pulmonary neuroepithelial bodies: extremely complex airway receptors. Anat Rec A Discov Mol Cell Evol Biol (2003) 1.01

Mice lacking Dfna5 show a diverging number of cochlear fourth row outer hair cells. Neurobiol Dis (2005) 1.01

The apolar channel in Cerebratulus lacteus hemoglobin is the route for O2 entry and exit. J Biol Chem (2008) 1.01

Domain analysis of Kv6.3, an electrically silent channel. J Physiol (2005) 1.01

Micro-Raman spectroscopy of natural and synthetic indigo samples. Analyst (2003) 1.01

Increased caspase activation and decreased TDP-43 solubility in progranulin knockout cortical cultures. J Neurochem (2010) 1.00

Current perspective of pathophysiological and interventional effects on endothelial progenitor cell biology: focus on PI3K/AKT/eNOS pathway. Int J Cardiol (2010) 1.00

Evidence for the presence of motilin, ghrelin, and the motilin and ghrelin receptor in neurons of the myenteric plexus. Regul Pept (2005) 1.00

Micro-CT of corrosion casts for use in the computer-aided design of microvasculature. Tissue Eng Part C Methods (2009) 0.99

Neurochemical pattern of the complex innervation of neuroepithelial bodies in mouse lungs. Histochem Cell Biol (2008) 0.99