Published in J Am Chem Soc on June 18, 2003
The structure of Clostridium perfringens NanI sialidase and its catalytic intermediates. J Biol Chem (2008) 1.19
Functional significance of the hemadsorption activity of influenza virus neuraminidase and its alteration in pandemic viruses. Arch Virol (2009) 1.15
Effects of Saccharide Spacing and Chain Extension on Toxin Inhibition by Glycopolypeptides of Well-Defined Architecture. Macromolecules (2007) 1.03
Neuraminidase-1, a subunit of the cell surface elastin receptor, desialylates and functionally inactivates adjacent receptors interacting with the mitogenic growth factors PDGF-BB and IGF-2. Am J Pathol (2008) 0.99
Effects of polymer structure on the inhibition of cholera toxin by linear polypeptide-based glycopolymers. Biomacromolecules (2006) 0.98
Lectin domains of polypeptide GalNAc transferases exhibit glycopeptide binding specificity. J Biol Chem (2011) 0.98
Portrait of an enzyme, a complete structural analysis of a multimodular {beta}-N-acetylglucosaminidase from Clostridium perfringens. J Biol Chem (2009) 0.96
Molecular basis of arabinobio-hydrolase activity in phytopathogenic fungi: crystal structure and catalytic mechanism of Fusarium graminearum GH93 exo-alpha-L-arabinanase. J Biol Chem (2009) 0.85
Dimer-monomer equilibrium of human thymidylate synthase monitored by fluorescence resonance energy transfer. Protein Sci (2010) 0.83
The Aspergillus fumigatus sialidase is a 3-deoxy-D-glycero-D-galacto-2-nonulosonic acid hydrolase (KDNase): structural and mechanistic insights. J Biol Chem (2011) 0.82
Sialidases from gut bacteria: a mini-review. Biochem Soc Trans (2016) 0.78
Microscale Measurements of Michaelis-Menten Constants of Neuraminidase with Nanogel Capillary Electrophoresis for the Determination of Sialic Acid Linkage. Anal Chem (2016) 0.77
Mutation of the Second Sialic Acid-Binding Site, Resulting in Reduced Neuraminidase Activity, Preceded the Emergence of H7N9 Influenza A Virus. J Virol (2017) 0.75
Visualizing metabolically labeled glycoconjugates of living cells by copper-free and fast huisgen cycloadditions. Angew Chem Int Ed Engl (2008) 5.90
Pannexin-1-mediated intracellular delivery of muramyl dipeptide induces caspase-1 activation via cryopyrin/NLRP3 independently of Nod2. J Immunol (2008) 2.65
A general strategy for the chemoenzymatic synthesis of asymmetrically branched N-glycans. Science (2013) 2.49
Robust immune responses elicited by a fully synthetic three-component vaccine. Nat Chem Biol (2007) 2.24
Opportunities and challenges in synthetic oligosaccharide and glycoconjugate research. Nat Chem (2009) 2.09
Peptidoglycan recognition proteins kill bacteria by activating protein-sensing two-component systems. Nat Med (2011) 1.97
Selective labeling of living cells by a photo-triggered click reaction. J Am Chem Soc (2009) 1.89
A synthetic lectin for O-linked beta-N-acetylglucosamine. Angew Chem Int Ed Engl (2009) 1.81
An angiogenic switch in macrophages involving synergy between Toll-like receptors 2, 4, 7, and 9 and adenosine A(2A) receptors. Am J Pathol (2003) 1.80
Modular synthesis of heparan sulfate oligosaccharides for structure-activity relationship studies. J Am Chem Soc (2009) 1.72
A general strategy for stereoselective glycosylations. J Am Chem Soc (2005) 1.70
The origin of the synergistic effect of muramyl dipeptide with endotoxin and peptidoglycan. J Biol Chem (2002) 1.53
Structural basis for peptidoglycan binding by peptidoglycan recognition proteins. Proc Natl Acad Sci U S A (2004) 1.50
Towards a fully synthetic carbohydrate-based anticancer vaccine: synthesis and immunological evaluation of a lipidated glycopeptide containing the tumor-associated tn antigen. Angew Chem Int Ed Engl (2005) 1.49
Immune recognition of tumor-associated mucin MUC1 is achieved by a fully synthetic aberrantly glycosylated MUC1 tripartite vaccine. Proc Natl Acad Sci U S A (2011) 1.46
Disease-specific non-reducing end carbohydrate biomarkers for mucopolysaccharidoses. Nat Chem Biol (2012) 1.43
Glycopeptide-specific monoclonal antibodies suggest new roles for O-GlcNAc. Nat Chem Biol (2010) 1.41
Combining high-energy C-trap dissociation and electron transfer dissociation for protein O-GlcNAc modification site assignment. J Proteome Res (2011) 1.41
Mechanism of class 1 (glycosylhydrolase family 47) {alpha}-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control. J Biol Chem (2005) 1.38
Glycopeptides as versatile tools for glycobiology. Glycobiology (2006) 1.36
Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs). Proc Natl Acad Sci U S A (2006) 1.35
The immunogenicity of the tumor-associated antigen Lewis(y) may be suppressed by a bifunctional cross-linker required for coupling to a carrier protein. Chemistry (2004) 1.35
Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins. Proc Natl Acad Sci U S A (2007) 1.27
Clathrin- and dynamin-dependent endocytic pathway regulates muramyl dipeptide internalization and NOD2 activation. J Immunol (2009) 1.26
Synthesis and Biological Activity of Natural Aminocyclopentitol Glycosidase Inhibitors: Mannostatins, Trehazolin, Allosamidins, and Their Analogues. Chem Rev (1999) 1.25
Practical approach for the stereoselective introduction of beta-arabinofuranosides. J Am Chem Soc (2006) 1.23
The extracytoplasmic domain of the Mycobacterium tuberculosis Ser/Thr kinase PknB binds specific muropeptides and is required for PknB localization. PLoS Pathog (2011) 1.21
Metal-free sequential [3 + 2]-dipolar cycloadditions using cyclooctynes and 1,3-dipoles of different reactivity. J Am Chem Soc (2010) 1.19
Stereoselective glycosylation reactions with chiral auxiliaries. Angew Chem Int Ed Engl (2005) 1.19
Protein modification by strain-promoted alkyne-nitrone cycloaddition. Angew Chem Int Ed Engl (2010) 1.17
Synthesis and antigenic analysis of the BclA glycoprotein oligosaccharide from the Bacillus anthracis exosporium. Chemistry (2006) 1.15
Immunotherapy for cancer: synthetic carbohydrate-based vaccines. Chem Commun (Camb) (2009) 1.14
Mechanistic insights into a Ca2+-dependent family of alpha-mannosidases in a human gut symbiont. Nat Chem Biol (2009) 1.14
Strain-promoted alkyne-azide cycloadditions (SPAAC) reveal new features of glycoconjugate biosynthesis. Chembiochem (2011) 1.10
Selective recognition of synthetic lysine and meso-diaminopimelic acid-type peptidoglycan fragments by human peptidoglycan recognition proteins I{alpha} and S. J Biol Chem (2005) 1.10
Increasing the antigenicity of synthetic tumor-associated carbohydrate antigens by targeting Toll-like receptors. Chembiochem (2009) 1.09
New set of orthogonal protecting groups for the modular synthesis of heparan sulfate fragments. Org Lett (2003) 1.06
Modulation of innate immune responses with synthetic lipid A derivatives. J Am Chem Soc (2007) 1.05
Dissecting the molecular basis of the role of the O-mannosylation pathway in disease: α-dystroglycan and forms of muscular dystrophy. Chembiochem (2013) 1.04
Crystal structure of human peptidoglycan recognition protein I alpha bound to a muramyl pentapeptide from Gram-positive bacteria. Protein Sci (2006) 1.04
Zebrafish peptidoglycan recognition proteins are bactericidal amidases essential for defense against bacterial infections. Immunity (2007) 1.02
Polar dibenzocyclooctynes for selective labeling of extracellular glycoconjugates of living cells. J Am Chem Soc (2012) 1.01
Binding and Cellular Activation Studies Reveal That Toll-like Receptor 2 Can Differentially Recognize Peptidoglycan from Gram-positive and Gram-negative Bacteria. J Biol Chem (2009) 1.01
Modification of the structure of peptidoglycan is a strategy to avoid detection by nucleotide-binding oligomerization domain protein 1. Infect Immun (2006) 1.00
Stereoselective glycosylations of 2-azido-2-deoxy-glucosides using intermediate sulfonium ions. Org Lett (2007) 1.00
Synthesis and biological evaluation of Rhizobium sin-1 lipid A derivatives. J Am Chem Soc (2003) 1.00
Preparation of well-defined antibody-drug conjugates through glycan remodeling and strain-promoted azide-alkyne cycloadditions. Angew Chem Int Ed Engl (2014) 0.99
Role of a cytoplasmic dual-function glycosyltransferase in O2 regulation of development in Dictyostelium. J Biol Chem (2009) 0.98
A fluorogenic probe for the catalyst-free detection of azide-tagged molecules. J Am Chem Soc (2012) 0.98
Differential induction of innate immune responses by synthetic lipid a derivatives. J Biol Chem (2010) 0.97
Probing the substrate specificity of Golgi alpha-mannosidase II by use of synthetic oligosaccharides and a catalytic nucleophile mutant. J Am Chem Soc (2008) 0.97
Versatile set of orthogonal protecting groups for the preparation of highly branched oligosaccharides. Org Lett (2010) 0.96
Structural basis of the inhibition of Golgi alpha-mannosidase II by mannostatin A and the role of the thiomethyl moiety in ligand-protein interactions. J Am Chem Soc (2006) 0.96
Multivariate analysis of electron detachment dissociation and infrared multiphoton dissociation mass spectra of heparan sulfate tetrasaccharides differing only in hexuronic acid stereochemistry. J Am Soc Mass Spectrom (2011) 0.95
Fluorous supported modular synthesis of heparan sulfate oligosaccharides. Org Lett (2013) 0.95
Innate immune responses of primary murine macrophage-lineage cells and RAW 264.7 cells to ligands of Toll-like receptors 2, 3, and 4. Comp Immunol Microbiol Infect Dis (2009) 0.94
Synthesis of potent bicyclic bisarylimidazole c-Jun N-terminal kinase inhibitors by catalytic C-H bond activation. J Am Chem Soc (2007) 0.94
Synthesis and biological evaluation of a lipid A derivative that contains an aminogluconate moiety. Chemistry (2004) 0.94
Adaptive immune activation: glycosylation does matter. Nat Chem Biol (2013) 0.93
Synthetic, structural, and biosynthetic studies of an unusual phospho-glycopeptide derived from α-dystroglycan. J Am Chem Soc (2011) 0.93
Negative electron transfer dissociation Fourier transform mass spectrometry of glycosaminoglycan carbohydrates. Eur J Mass Spectrom (Chichester, Eng) (2011) 0.92
Requirements for Skp1 processing by cytosolic prolyl 4(trans)-hydroxylase and α-N-acetylglucosaminyltransferase enzymes involved in O₂ signaling in dictyostelium. Biochemistry (2011) 0.92
Chiral-auxiliary-mediated 1,2-cis-glycosylations for the solid-supported synthesis of a biologically important branched alpha-glucan. Nat Chem (2010) 0.91
High-avidity, low-affinity multivalent interactions and the block to polyspermy in Xenopus laevis. J Am Chem Soc (2002) 0.91
Endolysins of Bacillus anthracis bacteriophages recognize unique carbohydrate epitopes of vegetative cell wall polysaccharides with high affinity and selectivity. J Am Chem Soc (2012) 0.91
Synthesis of glyco(lipo)peptides by liposome-mediated native chemical ligation. Org Lett (2006) 0.91
The reaction coordinate of a bacterial GH47 α-mannosidase: a combined quantum mechanical and structural approach. Angew Chem Int Ed Engl (2012) 0.91
The 2-aminogluconate isomer of rhizobium sin-1 lipid A can antagonize TNF-alpha production induced by enteric LPS. Chembiochem (2006) 0.90
Innate immune responses of synthetic lipid A derivatives of Neisseria meningitidis. Chemistry (2008) 0.90
Label-free detection of lectins on carbohydrate-modified boron-doped diamond surfaces. Anal Chem (2010) 0.90
Multifunctional surface modification of gold-stabilized nanoparticles by bioorthogonal reactions. J Am Chem Soc (2011) 0.90
Chemical synthesis and immunological evaluation of the inner core oligosaccharide of Francisella tularensis. J Am Chem Soc (2012) 0.89
Disaccharide mimetics of the aminoglycoside antibiotic neamine. Chembiochem (2004) 0.89
Direct and stereoselective synthesis of alpha-linked 2-deoxyglycosides. Org Lett (2008) 0.89
Stereoelectronic effects determine oxacarbenium vs β-sulfonium ion mediated glycosylations. Org Lett (2010) 0.88
Synthesis and proinflammatory properties of muramyl tripeptides containing lysine and diaminopimelic acid moieties. Chembiochem (2005) 0.87
Synthetic tetra-acylated derivatives of lipid A from Porphyromonas gingivalis are antagonists of human TLR4. Org Biomol Chem (2008) 0.87
Selective exo-enzymatic labeling of N-glycans on the surface of living cells by recombinant ST6Gal I. Angew Chem Int Ed Engl (2013) 0.86
The influence of the long chain fatty acid on the antagonistic activities of Rhizobium sin-1 lipid A. Bioorg Med Chem (2007) 0.86
Rapid assembly of oligosaccharides: a highly convergent strategy for the assembly of a glycosylated amino acid derived from PSGL-1. J Org Chem (2009) 0.85
Chemical synthesis and proinflammatory responses of monophosphoryl lipid A adjuvant candidates. European J Org Chem (2010) 0.84
Glycan-functionalized diamond nanoparticles as potent E. coli anti-adhesives. Nanoscale (2013) 0.84
Immune and anticancer responses elicited by fully synthetic aberrantly glycosylated MUC1 tripartite vaccines modified by a TLR2 or TLR9 agonist. Chembiochem (2014) 0.84
Convergent assembly and surface modification of multifunctional dendrimers by three consecutive click reactions. Chemistry (2010) 0.84
Two-step bioorthogonal activity-based proteasome profiling using copper-free click reagents: a comparative study. Bioorg Med Chem (2011) 0.83
Spin-labeled analogs of CMP-NeuAc as NMR probes of the alpha-2,6-sialyltransferase ST6Gal I. Chem Biol (2007) 0.83
Comparison of photo- and Cu(I)-catalyzed "click" chemistries for the formation of carbohydrate SPR interfaces. Analyst (2012) 0.83
Crystal structure of a peptidoglycan recognition protein (PGRP) in complex with a muramyl tripeptide from Gram-positive bacteria. J Endotoxin Res (2005) 0.83
Surface modification of polymeric micelles by strain-promoted alkyne-azide cycloadditions. Chemistry (2010) 0.83
ELECTRON DETACHMENT DISSOCIATION OF SYNTHETIC HEPARAN SULFATE GLYCOSAMINOGLYCAN TETRASACCHARIDES VARYING IN DEGREE OF SULFATION AND HEXURONIC ACID STEREOCHEMISTRY. Int J Mass Spectrom (2012) 0.82
High-field asymmetric-waveform ion mobility spectrometry and electron detachment dissociation of isobaric mixtures of glycosaminoglycans. J Am Soc Mass Spectrom (2013) 0.82
Agonistic and antagonistic properties of a Rhizobium sin-1 lipid A modified by an ether-linked lipid. Org Biomol Chem (2007) 0.82
Inhibition of Golgi mannosidase II with mannostatin A analogues: synthesis, biological evaluation, and structure-activity relationship studies. Chembiochem (2004) 0.82
Abnormal accumulation and recycling of glycoproteins visualized in Niemann-Pick type C cells using the chemical reporter strategy. Proc Natl Acad Sci U S A (2013) 0.82