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1
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Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals.
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Mol Cell
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2008
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1.71
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2
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Induction of Ca²+-driven apoptosis in chronic lymphocytic leukemia cells by peptide-mediated disruption of Bcl-2-IP3 receptor interaction.
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Blood
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2010
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1.68
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3
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The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor.
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Proc Natl Acad Sci U S A
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2009
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1.61
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4
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Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis.
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Proc Natl Acad Sci U S A
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2008
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1.59
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5
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Regulation of InsP3 receptor activity by neuronal Ca2+-binding proteins.
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EMBO J
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2003
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1.58
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6
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Pannexins, distant relatives of the connexin family with specific cellular functions?
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Bioessays
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2009
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1.50
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7
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Functional characterization of mammalian inositol 1,4,5-trisphosphate receptor isoforms.
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Biophys J
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2004
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1.43
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8
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Up-regulation of inositol 1,4,5-trisphosphate receptor type 1 is responsible for a decreased endoplasmic-reticulum Ca2+ content in presenilin double knock-out cells.
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Cell Calcium
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2006
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1.40
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9
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Caspase-3-induced truncation of type 1 inositol trisphosphate receptor accelerates apoptotic cell death and induces inositol trisphosphate-independent calcium release during apoptosis.
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J Biol Chem
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2004
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1.36
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10
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Intracellular Ca2+ storage in health and disease: a dynamic equilibrium.
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Cell Calcium
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2010
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1.32
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11
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Endoplasmic-reticulum calcium depletion and disease.
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Cold Spring Harb Perspect Biol
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2011
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1.31
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12
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Regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release by reversible phosphorylation and dephosphorylation.
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Biochim Biophys Acta
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2008
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1.27
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13
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The IP(3) receptor-mitochondria connection in apoptosis and autophagy.
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Biochim Biophys Acta
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2010
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1.22
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14
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Identification and functional analysis of two Ca2+-binding EF-hand motifs in the B"/PR72 subunit of protein phosphatase 2A.
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J Biol Chem
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2003
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1.21
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15
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Thimerosal stimulates Ca2+ flux through inositol 1,4,5-trisphosphate receptor type 1, but not type 3, via modulation of an isoform-specific Ca2+-dependent intramolecular interaction.
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Biochem J
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2004
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1.19
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16
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Ins(1,4,5)P3 receptor-mediated Ca2+ signaling and autophagy induction are interrelated.
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Autophagy
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2011
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1.16
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17
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Phosphorylation of IP3R1 and the regulation of [Ca2+]i responses at fertilization: a role for the MAP kinase pathway.
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Development
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2006
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1.14
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18
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Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity.
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FASEB J
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2010
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1.10
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19
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Polycystin-2 activation by inositol 1,4,5-trisphosphate-induced Ca2+ release requires its direct association with the inositol 1,4,5-trisphosphate receptor in a signaling microdomain.
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J Biol Chem
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2010
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1.10
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20
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TRPM8-independent menthol-induced Ca2+ release from endoplasmic reticulum and Golgi.
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J Biol Chem
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2006
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1.09
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21
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The Ca2+/Mn2+ pumps in the Golgi apparatus.
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Biochim Biophys Acta
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2004
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1.09
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22
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SPCA1 pumps and Hailey-Hailey disease.
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Biochem Biophys Res Commun
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2004
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1.08
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23
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The C terminus of Bax inhibitor-1 forms a Ca2+-permeable channel pore.
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J Biol Chem
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2011
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1.07
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24
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Protein phosphatase-1 is a novel regulator of the interaction between IRBIT and the inositol 1,4,5-trisphosphate receptor.
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Biochem J
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2007
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1.05
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25
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mTOR-Controlled Autophagy Requires Intracellular Ca(2+) Signaling.
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PLoS One
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2013
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1.02
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26
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IP(3) Receptors, Mitochondria, and Ca Signaling: Implications for Aging.
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J Aging Res
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2011
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1.02
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27
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Pannexin channels in ATP release and beyond: an unexpected rendezvous at the endoplasmic reticulum.
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Cell Signal
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2010
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1.01
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28
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Uncoupled IP3 receptor can function as a Ca2+-leak channel: cell biological and pathological consequences.
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Biol Cell
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2006
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0.99
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29
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Regulation of the phosphorylation of the inositol 1,4,5-trisphosphate receptor by protein kinase C.
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Biochem Biophys Res Commun
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2004
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0.98
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30
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Caspase-3-truncated type 1 inositol 1,4,5-trisphosphate receptor enhances intracellular Ca2+ leak and disturbs Ca2+ signalling.
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Biol Cell
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2008
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0.97
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31
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Inositol 1,4,5-trisphosphate receptor 1, a widespread Ca2+ channel, is a novel substrate of polo-like kinase 1 in eggs.
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Dev Biol
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2008
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0.94
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32
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Regulation of inositol 1,4,5-trisphosphate receptors during endoplasmic reticulum stress.
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Biochim Biophys Acta
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2013
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0.94
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33
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STIM1 as a key regulator for Ca2+ homeostasis in skeletal-muscle development and function.
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Skelet Muscle
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2011
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0.94
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34
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Endogenously bound calmodulin is essential for the function of the inositol 1,4,5-trisphosphate receptor.
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J Biol Chem
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2006
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0.93
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35
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Biphenyl 2,3',4,5',6-pentakisphosphate, a novel inositol polyphosphate surrogate, modulates Ca2+ responses in rat hepatocytes.
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FASEB J
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2007
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0.93
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36
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The three isoenzymes of human inositol-1,4,5-trisphosphate 3-kinase show specific intracellular localization but comparable Ca2+ responses on transfection in COS-7 cells.
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Biochem J
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2003
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0.92
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37
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The complex regulatory function of the ligand-binding domain of the inositol 1,4,5-trisphosphate receptor.
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Cell Calcium
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2007
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0.92
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38
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Microtubule-dependent redistribution of the type-1 inositol 1,4,5-trisphosphate receptor in A7r5 smooth muscle cells.
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J Cell Sci
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2003
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0.92
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39
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Binding of IRBIT to the IP3 receptor: determinants and functional effects.
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Biochem Biophys Res Commun
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2006
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0.92
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40
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Inositol 1,4,5-trisphosphate and its receptors.
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Adv Exp Med Biol
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2012
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0.90
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41
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Molecular and functional characterization of inositol trisphosphate receptors during early zebrafish development.
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J Biol Chem
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2007
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0.89
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42
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The contribution of the SPCA1 Ca2+ pump to the Ca2+ accumulation in the Golgi apparatus of HeLa cells assessed via RNA-mediated interference.
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Biochem Biophys Res Commun
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2003
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0.89
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43
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Regulation of inositol 1,4,5-trisphosphate receptor type 1 function during oocyte maturation by MPM-2 phosphorylation.
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Cell Calcium
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2009
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0.88
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44
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The role of calmodulin for inositol 1,4,5-trisphosphate receptor function.
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Biochim Biophys Acta
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2002
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0.88
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45
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Cell cycle-coupled [Ca(2+)](i) oscillations in mouse zygotes and function of the inositol 1,4,5-trisphosphate receptor-1.
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Dev Biol
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2004
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0.88
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46
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The suppressor domain of inositol 1,4,5-trisphosphate receptor plays an essential role in the protection against apoptosis.
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Cell Calcium
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2006
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0.87
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47
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The IRBIT domain adds new functions to the AHCY family.
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Bioessays
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2008
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0.85
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48
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A novel Ca2+-induced Ca2+ release mechanism in A7r5 cells regulated by calmodulin-like proteins.
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J Biol Chem
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2003
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0.84
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49
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Profiling of the Bcl-2/Bcl-X(L)-binding sites on type 1 IP(3) receptor.
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Biochem Biophys Res Commun
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2012
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0.84
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50
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Inhibition of the inositol trisphosphate receptor of mouse eggs and A7r5 cells by KN-93 via a mechanism unrelated to Ca2+/calmodulin-dependent protein kinase II antagonism.
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J Biol Chem
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2002
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0.84
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51
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STIM1, but not STIM2, is required for proper agonist-induced Ca2+ signaling.
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Cell Calcium
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2010
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0.84
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52
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The 12 kDa FK506-binding protein, FKBP12, modulates the Ca(2+)-flux properties of the type-3 ryanodine receptor.
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J Cell Sci
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2004
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0.83
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53
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Suramin and disulfonated stilbene derivatives stimulate the Ca2+-induced Ca2+ -release mechanism in A7r5 cells.
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Mol Pharmacol
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2005
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0.82
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54
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Long-lasting changes in GABA responsiveness in cultured neurons.
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Neurosci Lett
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2004
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0.81
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55
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Alpha-helical destabilization of the Bcl-2-BH4-domain peptide abolishes its ability to inhibit the IP3 receptor.
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PLoS One
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2013
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0.81
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56
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Ca2+ uptake and release properties of a thapsigargin-insensitive nonmitochondrial Ca2+ store in A7r5 and 16HBE14o- cells.
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J Biol Chem
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2001
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0.80
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57
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Bax Inhibitor-1-mediated Ca2+ leak is decreased by cytosolic acidosis.
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Cell Calcium
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2013
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0.80
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58
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HA14-1, but not the BH3 mimetic ABT-737, causes Ca2+ dysregulation in platelets and human cell lines.
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Haematologica
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2013
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0.78
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59
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Unraveling the role of polycystin-2/inositol 1,4,5-trisphosphate receptor interaction in Ca signaling.
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Commun Integr Biol
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2010
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0.77
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Calmodulin and calcium-release channels.
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Biol Res
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2004
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0.76
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61
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Characterization of Ca2+ release from heterogeneous Ca2+ stores in sarcoplasmic reticulum isolated from arterial and gastric smooth muscle.
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Can J Physiol Pharmacol
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2002
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0.76
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62
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Ca(2+) signals in Pmr1-GFP-expressing COS-1 cells with functional endoplasmic reticulum.
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Biochem Biophys Res Commun
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2002
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0.75
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63
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Polycystin-1 but not polycystin-2 deficiency causes upregulation of the mTOR pathway and can be synergistically targeted with rapamycin and metformin.
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Pflugers Arch
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2013
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0.75
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Measurement of intracellular Ca2+ release in intact and permeabilized cells using 45Ca2+.
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Cold Spring Harb Protoc
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2014
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0.75
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65
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Measurement of intracellular Ca2+ release in intact cells using 45Ca2+.
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Cold Spring Harb Protoc
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2014
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0.75
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66
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Measurement of intracellular Ca2+ release in permeabilized cells using 45Ca2+.
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Cold Spring Harb Protoc
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2014
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0.75
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Heterogeneous nuclear ribonucleoprotein h1, a novel nuclear autoantigen.
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Clin Chem
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2009
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0.75
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