Published in J Biol Chem on December 01, 2006
The Concise Guide to PHARMACOLOGY 2013/14: ion channels. Br J Pharmacol (2013) 3.03
The role of transient receptor potential cation channels in Ca2+ signaling. Cold Spring Harb Perspect Biol (2010) 1.56
Differential ATF3 expression in dorsal root ganglion neurons reveals the profile of primary afferents engaged by diverse noxious chemical stimuli. Pain (2010) 1.22
The contribution of TRPM8 and TRPA1 channels to cold allodynia and neuropathic pain. PLoS One (2009) 1.18
Human lung epithelial cells express a functional cold-sensing TRPM8 variant. Am J Respir Cell Mol Biol (2008) 1.12
Ligand stoichiometry of the cold- and menthol-activated channel TRPM8. J Physiol (2011) 1.10
TRPM8, a versatile channel in human sperm. PLoS One (2009) 1.05
Menthol activation of corneal cool cells induces TRPM8-mediated lacrimation but not nociceptive responses in rodents. Invest Ophthalmol Vis Sci (2012) 0.95
Vanilloid and melastatin transient receptor potential channels in vascular smooth muscle. Microcirculation (2010) 0.94
TRPM8 ion channels differentially modulate proliferation and cell cycle distribution of normal and cancer prostate cells. PLoS One (2012) 0.93
Calcium wave signaling in cancer cells. Life Sci (2010) 0.91
Rapid, opioid-sensitive mechanisms involved in transient receptor potential vanilloid 1 sensitization. J Biol Chem (2008) 0.90
Shivering and tachycardic responses to external cooling in mice are substantially suppressed by TRPV1 activation but not by TRPM8 inhibition. Am J Physiol Regul Integr Comp Physiol (2013) 0.89
Pharmacological and functional properties of TRPM8 channels in prostate tumor cells. Pflugers Arch (2010) 0.88
Orais and STIMs: physiological mechanisms and disease. J Cell Mol Med (2012) 0.87
The TRPM8 ion channel comprises direct Gq protein-activating capacity. Pflugers Arch (2012) 0.86
Thermosensory and mechanosensory perception in human genetic disease. Hum Mol Genet (2009) 0.81
Pathogenic role of store-operated and receptor-operated ca(2+) channels in pulmonary arterial hypertension. J Signal Transduct (2012) 0.79
Increasing the expression of calcium-permeable TRPC3 and TRPC7 channels enhances constitutive secretion. Biochem J (2008) 0.79
Bidirectional modulation of thermal and chemical sensitivity of TRPM8 channels by the initial region of the N-terminal domain. J Biol Chem (2014) 0.78
The Golgi apparatus is a functionally distinct Ca2+ store regulated by the PKA and Epac branches of the β1-adrenergic signaling pathway. Sci Signal (2015) 0.78
Menthol Enhances an Antiproliferative Activity of 1alpha,25-Dihydroxyvitamin D(3) in LNCaP Cells. J Clin Biochem Nutr (2009) 0.75
TRPM8 in the negative regulation of TNFα expression during cold stress. Sci Rep (2017) 0.75
Emerging Families of Ion Channels Involved in Urinary Bladder Nociception. Pharmaceuticals (Basel) (2010) 0.75
TRPM8 Channel Activation Induced by Monoterpenoid Rotundifolone Underlies Mesenteric Artery Relaxation. PLoS One (2015) 0.75
Ion channel mechanisms of rat tail artery contraction-relaxation by menthol involving, respectively, TRPM8 activation and L-type Ca2+ channel inhibition. Am J Physiol Heart Circ Physiol (2016) 0.75
Menthol evokes Ca(2+) signals and induces oxidative stress independently of the presence of TRPM8 (menthol) receptor in cancer cells. Redox Biol (2017) 0.75
Cellular and Molecular Targets of Menthol Actions. Front Pharmacol (2017) 0.75
Transient receptor potential cation channels in disease. Physiol Rev (2007) 6.91
The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels. Nature (2004) 5.76
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels. Nature (2003) 4.45
TRPA1 acts as a cold sensor in vitro and in vivo. Proc Natl Acad Sci U S A (2009) 3.46
TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption. J Biol Chem (2003) 3.15
Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives. J Biol Chem (2002) 3.14
TRP channels: an overview. Cell Calcium (2005) 2.98
Permeation and selectivity of TRP channels. Annu Rev Physiol (2006) 2.96
TRPP2 and TRPV4 form a polymodal sensory channel complex. J Cell Biol (2008) 2.88
Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cells. J Biol Chem (2002) 2.87
Bimodal action of menthol on the transient receptor potential channel TRPA1. J Neurosci (2007) 2.78
Calcium absorption across epithelia. Physiol Rev (2005) 2.57
Heat activation of TRPM5 underlies thermal sensitivity of sweet taste. Nature (2005) 2.52
Sensing with TRP channels. Nat Chem Biol (2005) 2.51
TRPM8 voltage sensor mutants reveal a mechanism for integrating thermal and chemical stimuli. Nat Chem Biol (2007) 2.48
TRPV4 calcium entry channel: a paradigm for gating diversity. Am J Physiol Cell Physiol (2004) 2.35
TRPM3 is a nociceptor channel involved in the detection of noxious heat. Neuron (2011) 2.31
Gating of TRP channels: a voltage connection? J Physiol (2005) 2.30
Molecular determinants of permeation through the cation channel TRPV4. J Biol Chem (2002) 2.24
Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia. Nat Genet (2008) 2.24
The Ca2+-activated cation channel TRPM4 is regulated by phosphatidylinositol 4,5-biphosphate. EMBO J (2006) 2.22
Voltage dependence of the Ca2+-activated cation channel TRPM4. J Biol Chem (2003) 2.21
Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding. J Clin Invest (2007) 2.19
Chronic administration of anticholinergics in rats induces a shift from muscarinic to purinergic transmission in the bladder wall. Eur Urol (2013) 2.15
The vanilloid transient receptor potential channel TRPV4: from structure to disease. Prog Biophys Mol Biol (2009) 2.13
TRPs in our senses. Curr Biol (2008) 2.12
The transient receptor potential family of ion channels. Genome Biol (2011) 2.08
Mutations in the gene encoding the calcium-permeable ion channel TRPV4 produce spondylometaphyseal dysplasia, Kozlowski type and metatropic dysplasia. Am J Hum Genet (2009) 2.02
Pharmacology of vanilloid transient receptor potential cation channels. Mol Pharmacol (2009) 2.00
Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex. EMBO J (2003) 1.97
Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis. Proc Natl Acad Sci U S A (2010) 1.96
CAPS1 regulates catecholamine loading of large dense-core vesicles. Neuron (2005) 1.94
Transient receptor potential channels meet phosphoinositides. EMBO J (2008) 1.89
Regulation of the Ca2+ sensitivity of the nonselective cation channel TRPM4. J Biol Chem (2004) 1.82
Outer pore architecture of a Ca2+-selective TRP channel. J Biol Chem (2004) 1.79
TRPV4-mediated calcium influx regulates terminal differentiation of osteoclasts. Cell Metab (2008) 1.79
Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals. Mol Cell (2008) 1.71
PACSINs bind to the TRPV4 cation channel. PACSIN 3 modulates the subcellular localization of TRPV4. J Biol Chem (2006) 1.71
Comparison of functional properties of the Ca2+-activated cation channels TRPM4 and TRPM5 from mice. Cell Calcium (2005) 1.70
The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system. Brain (2011) 1.70
Induction of Ca²+-driven apoptosis in chronic lymphocytic leukemia cells by peptide-mediated disruption of Bcl-2-IP3 receptor interaction. Blood (2010) 1.68
Increased IgE-dependent mast cell activation and anaphylactic responses in mice lacking the calcium-activated nonselective cation channel TRPM4. Nat Immunol (2007) 1.68
Neuronal TRP channels: thermometers, pathfinders and life-savers. Trends Neurosci (2008) 1.63
The transient receptor potential channel TRPA1: from gene to pathophysiology. Pflugers Arch (2012) 1.63
The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor. Proc Natl Acad Sci U S A (2009) 1.61
Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis. Proc Natl Acad Sci U S A (2008) 1.59
Regulation of InsP3 receptor activity by neuronal Ca2+-binding proteins. EMBO J (2003) 1.58
The role of transient receptor potential cation channels in Ca2+ signaling. Cold Spring Harb Perspect Biol (2010) 1.56
The capsaicin receptor TRPV1 is a crucial mediator of the noxious effects of mustard oil. Curr Biol (2011) 1.56
TRP channels: a TR(I)P through a world of multifunctional cation channels. Pflugers Arch (2005) 1.54
Molecular mechanism of active Ca2+ reabsorption in the distal nephron. Annu Rev Physiol (2002) 1.51
Pannexins, distant relatives of the connexin family with specific cellular functions? Bioessays (2009) 1.50
The loss and progressive recovery of voiding after spinal cord interruption in rats is associated with simultaneous changes in autonomous contractile bladder activity. Eur Urol (2008) 1.48
The SNARE protein SNAP-25 is linked to fast calcium triggering of exocytosis. Proc Natl Acad Sci U S A (2002) 1.46
Loss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5-/- mice. Proc Natl Acad Sci U S A (2010) 1.46
Nicotine activates the chemosensory cation channel TRPA1. Nat Neurosci (2009) 1.44