Published in J Biol Chem on June 16, 2003
Direct observation of base-pair stepping by RNA polymerase. Nature (2005) 6.29
Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation. Cell (2005) 2.88
Genomic transcriptional response to loss of chromosomal supercoiling in Escherichia coli. Genome Biol (2004) 2.60
Single-molecule studies of RNA polymerase: motoring along. Annu Rev Biochem (2008) 1.80
Discrimination against deoxyribonucleotide substrates by bacterial RNA polymerase. J Biol Chem (2004) 1.29
Transcriptional bypass of bulky DNA lesions causes new mutant RNA transcripts in human cells. EMBO Rep (2007) 1.23
Complete dissection of transcription elongation reveals slow translocation of RNA polymerase II in a linear ratchet mechanism. Elife (2013) 1.14
A unified model of transcription elongation: what have we learned from single-molecule experiments? Biophys J (2011) 1.00
Interaction of RNA polymerase II fork loop 2 with downstream non-template DNA regulates transcription elongation. J Biol Chem (2011) 0.96
Templated nucleoside triphosphate binding to a noncatalytic site on RNA polymerase regulates transcription. Proc Natl Acad Sci U S A (2011) 0.91
RNA polymerase stalls in a post-translocated register and can hyper-translocate. Transcription (2012) 0.90
Forks, pincers, and triggers: the tools for nucleotide incorporation and translocation in multi-subunit RNA polymerases. Curr Opin Struct Biol (2009) 0.89
Human RNA polymerase II elongation in slow motion: role of the TFIIF RAP74 alpha1 helix in nucleoside triphosphate-driven translocation. Mol Cell Biol (2005) 0.87
Trigger loop folding determines transcription rate of Escherichia coli's RNA polymerase. Proc Natl Acad Sci U S A (2014) 0.83
Differential blocking effects of the acetaldehyde-derived DNA lesion N2-ethyl-2'-deoxyguanosine on transcription by multisubunit and single subunit RNA polymerases. J Biol Chem (2008) 0.82
Single-molecule studies of RNAPII elongation. Biochim Biophys Acta (2012) 0.80
Backtracked and paused transcription initiation intermediate of Escherichia coli RNA polymerase. Proc Natl Acad Sci U S A (2016) 0.79
Importance of steric effects on the efficiency and fidelity of transcription by T7 RNA polymerase. Biochemistry (2011) 0.78
Structural Model of RNA Polymerase II Elongation Complex with Complete Transcription Bubble Reveals NTP Entry Routes. PLoS Comput Biol (2015) 0.77
A structure-based kinetic model of transcription. Transcription (2016) 0.75
Translocation and fidelity of Escherichia coli RNA polymerase. Transcription (2013) 0.75
DNA mismatch repair. Annu Rev Biochem (2005) 8.21
DNA bending and unbending by MutS govern mismatch recognition and specificity. Proc Natl Acad Sci U S A (2003) 1.92
A model for oligomeric regulation of APOBEC3G cytosine deaminase-dependent restriction of HIV. J Biol Chem (2008) 1.62
Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA. DNA Repair (Amst) (2007) 1.57
Determination of protein-DNA binding constants and specificities from statistical analyses of single molecules: MutS-DNA interactions. Nucleic Acids Res (2005) 1.48
Structural model for deoxycytidine deamination mechanisms of the HIV-1 inactivation enzyme APOBEC3G. J Biol Chem (2010) 1.42
Direct visualization of asymmetric adenine-nucleotide-induced conformational changes in MutL alpha. Mol Cell (2008) 1.38
Quantitative characterization of biomolecular assemblies and interactions using atomic force microscopy. Methods (2003) 1.34
Functional oligomeric state of avian sarcoma virus integrase. J Biol Chem (2002) 1.31
Transcript cleavage by Thermus thermophilus RNA polymerase. Effects of GreA and anti-GreA factors. J Biol Chem (2001) 1.24
Interconvertible lac repressor-DNA loops revealed by single-molecule experiments. PLoS Biol (2008) 1.23
UvrB domain 4, an autoinhibitory gate for regulation of DNA binding and ATPase activity. J Biol Chem (2006) 1.20
Large conformational changes in MutS during DNA scanning, mismatch recognition and repair signalling. EMBO J (2012) 1.20
A minimal exonuclease domain of WRN forms a hexamer on DNA and possesses both 3'- 5' exonuclease and 5'-protruding strand endonuclease activities. Biochemistry (2002) 1.19
Crystal structure of Thermus aquaticus Gfh1, a Gre-factor paralog that inhibits rather than stimulates transcript cleavage. J Mol Biol (2005) 1.11
Functional characterization and atomic force microscopy of a DNA repair protein conjugated to a quantum dot. Nano Lett (2008) 1.09
Unactivated PKR exists in an open conformation capable of binding nucleotides. Biochemistry (2006) 1.06
Mechanism of MutS searching for DNA mismatches and signaling repair. J Biol Chem (2008) 1.06
Single-molecule FRET TACKLE reveals highly dynamic mismatched DNA-MutS complexes. Biochemistry (2010) 1.04
Angiopoietin-like protein 4 inhibition of lipoprotein lipase: evidence for reversible complex formation. J Biol Chem (2013) 1.03
Kinetic investigation of Escherichia coli RNA polymerase mutants that influence nucleotide discrimination and transcription fidelity. J Biol Chem (2006) 0.98
Four-color single-molecule fluorescence with noncovalent dye labeling to monitor dynamic multimolecular complexes. Biotechniques (2010) 0.92
Templated nucleoside triphosphate binding to a noncatalytic site on RNA polymerase regulates transcription. Proc Natl Acad Sci U S A (2011) 0.91
AFM studies on the role of the protein RdgC in bacterial DNA recombination. J Mol Biol (2005) 0.89
Biochemical analysis of the human mismatch repair proteins hMutSα MSH2(G674A)-MSH6 and MSH2-MSH6(T1219D). J Biol Chem (2012) 0.87
DNA binding properties of the yeast Msh2-Msh6 and Mlh1-Pms1 heterodimers. Biol Chem (2002) 0.87
Long-range architecture in a viral RNA genome. Biochemistry (2013) 0.86
Linear Streptomyces plasmids form superhelical circles through interactions between their terminal proteins. Nucleic Acids Res (2010) 0.84
Atomic force microscopy studies of DNA-wrapped carbon nanotube structure and binding to quantum dots. J Am Chem Soc (2008) 0.83
Catching RNA polymerase in the act of binding: intermediates in transcription illuminated by synchrotron footprinting. Proc Natl Acad Sci U S A (2005) 0.81
Dynamics of MutS-mismatched DNA complexes are predictive of their repair phenotypes. Biochemistry (2014) 0.81
Kinetics of multisubunit RNA polymerases: experimental methods and data analysis. Methods Enzymol (2003) 0.80
Corrigendum: Transcription errors induce proteotoxic stress and shorten cellular lifespan. Nat Commun (2015) 0.76