Published in J Biol Chem on April 04, 2006
Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA. DNA Repair (Amst) (2007) 1.57
Collaborative dynamic DNA scanning by nucleotide excision repair proteins investigated by single- molecule imaging of quantum-dot-labeled proteins. Mol Cell (2010) 1.40
Functional and structural studies of the nucleotide excision repair helicase XPD suggest a polarity for DNA translocation. EMBO J (2011) 1.28
Controlling the motor activity of a transcription-repair coupling factor: autoinhibition and the role of RNA polymerase. Nucleic Acids Res (2007) 1.20
Prokaryotic nucleotide excision repair. Cold Spring Harb Perspect Biol (2013) 1.16
Functional characterization and atomic force microscopy of a DNA repair protein conjugated to a quantum dot. Nano Lett (2008) 1.09
DNA tandem lesion repair by strand displacement synthesis and nucleotide excision repair. Biochemistry (2008) 1.03
An N-terminal clamp restrains the motor domains of the bacterial transcription-repair coupling factor Mfd. Nucleic Acids Res (2009) 0.99
Removal of misincorporated ribonucleotides from prokaryotic genomes: an unexpected role for nucleotide excision repair. PLoS Genet (2013) 0.98
Nucleotide excision repair of a DNA interstrand cross-link produces single- and double-strand breaks. Biochemistry (2010) 0.97
NMR analysis of [methyl-13C]methionine UvrB from Bacillus caldotenax reveals UvrB-domain 4 heterodimer formation in solution. J Mol Biol (2007) 0.95
Dynamics of lesion processing by bacterial nucleotide excision repair proteins. Prog Mol Biol Transl Sci (2012) 0.93
Cooperative damage recognition by UvrA and UvrB: identification of UvrA residues that mediate DNA binding. DNA Repair (Amst) (2008) 0.91
DNA wrapping is required for DNA damage recognition in the Escherichia coli DNA nucleotide excision repair pathway. Proc Natl Acad Sci U S A (2009) 0.89
Real-time single-molecule imaging reveals a direct interaction between UvrC and UvrB on DNA tightropes. Nucleic Acids Res (2013) 0.88
Exploring damage recognition models in prokaryotic nucleotide excision repair with a benzo[a]pyrene-derived lesion in UvrB. Biochemistry (2009) 0.88
Repair of hydantoin lesions and their amine adducts in DNA by base and nucleotide excision repair. J Am Chem Soc (2013) 0.87
Single-molecule analysis reveals two separate DNA-binding domains in the Escherichia coli UvrA dimer. Nucleic Acids Res (2009) 0.84
Excision of a lyase-resistant oxidized abasic lesion from DNA. Chem Res Toxicol (2010) 0.84
Multipartite control of the DNA translocase, Mfd. Nucleic Acids Res (2012) 0.80
Crystal structure of the UvrB dimer: insights into the nature and functioning of the UvrAB damage engagement and UvrB-DNA complexes. Nucleic Acids Res (2012) 0.80
Nucleotide excision repair of chemically stabilized analogues of DNA interstrand cross-links produced from oxidized abasic sites. Biochemistry (2014) 0.78
Investigation of bacterial nucleotide excision repair using single-molecule techniques. DNA Repair (Amst) (2014) 0.76
Conservation and Divergence in Nucleotide Excision Repair Lesion Recognition. J Biol Chem (2016) 0.75
Repair of the major lesion resulting from C5'-oxidation of DNA. Biochemistry (2011) 0.75
DNA mismatch repair. Annu Rev Biochem (2005) 8.21
Standardizing global gene expression analysis between laboratories and across platforms. Nat Methods (2005) 6.23
Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells. Methods Mol Biol (2006) 2.87
Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro. Mol Cell Biol (2004) 2.65
Energy metabolism in human pluripotent stem cells and their differentiated counterparts. PLoS One (2011) 2.64
Prokaryotic nucleotide excision repair: the UvrABC system. Chem Rev (2006) 2.37
Basal transcription defect discriminates between xeroderma pigmentosum and trichothiodystrophy in XPD patients. Mol Cell (2003) 2.12
DNA bending and unbending by MutS govern mismatch recognition and specificity. Proc Natl Acad Sci U S A (2003) 1.92
Integrating phenotypic and expression profiles to map arsenic-response networks. Genome Biol (2004) 1.90
High-mobility group box 1 is essential for mitochondrial quality control. Cell Metab (2011) 1.89
Adipose tissue and adipocytes support tumorigenesis and metastasis. Biochim Biophys Acta (2013) 1.85
Crystal structure of the FeS cluster-containing nucleotide excision repair helicase XPD. PLoS Biol (2008) 1.81
Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair. Nature (2011) 1.80
Role of mitochondria in toxic oxidative stress. Mol Interv (2005) 1.76
Alterations in bioenergetics due to changes in mitochondrial DNA copy number. Methods (2010) 1.62
A model for oligomeric regulation of APOBEC3G cytosine deaminase-dependent restriction of HIV. J Biol Chem (2008) 1.62
NIEHS extramural global environmental health portfolio: opportunities for collaboration. Environ Health Perspect (2008) 1.61
Mitochondrial dysfunction in neurodegenerative diseases and cancer. Environ Mol Mutagen (2010) 1.60
Mitochondrial DNA repair and aging. Mutat Res (2002) 1.60
Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA. DNA Repair (Amst) (2007) 1.57
Structural basis for DNA recognition and processing by UvrB. Nat Struct Mol Biol (2006) 1.51
Cell sorting experiments link persistent mitochondrial DNA damage with loss of mitochondrial membrane potential and apoptotic cell death. J Biol Chem (2002) 1.49
Determination of protein-DNA binding constants and specificities from statistical analyses of single molecules: MutS-DNA interactions. Nucleic Acids Res (2005) 1.48
Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species. PLoS One (2011) 1.48
Phenethyl isothiocyanate inhibits oxidative phosphorylation to trigger reactive oxygen species-mediated death of human prostate cancer cells. J Biol Chem (2010) 1.46
The beta -hairpin motif of UvrB is essential for DNA binding, damage processing, and UvrC-mediated incisions. J Biol Chem (2001) 1.46
Structural model for deoxycytidine deamination mechanisms of the HIV-1 inactivation enzyme APOBEC3G. J Biol Chem (2010) 1.42
Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy. J Exp Med (2012) 1.42
Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans. Genome Biol (2007) 1.41
Collaborative dynamic DNA scanning by nucleotide excision repair proteins investigated by single- molecule imaging of quantum-dot-labeled proteins. Mol Cell (2010) 1.40
Metabolic symbiosis in cancer: refocusing the Warburg lens. Mol Carcinog (2012) 1.40
Measuring oxidative mtDNA damage and repair using quantitative PCR. Methods Mol Biol (2002) 1.40
'Close-fitting sleeves': DNA damage recognition by the UvrABC nuclease system. Mutat Res (2005) 1.39
Direct visualization of asymmetric adenine-nucleotide-induced conformational changes in MutL alpha. Mol Cell (2008) 1.38
Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage. Aging Cell (2004) 1.37
Quantitative characterization of biomolecular assemblies and interactions using atomic force microscopy. Methods (2003) 1.34
Mitochondrial localization of telomerase as a determinant for hydrogen peroxide-induced mitochondrial DNA damage and apoptosis. Hum Mol Genet (2006) 1.32
Altered gene expression and DNA damage in peripheral blood cells from Friedreich's ataxia patients: cellular model of pathology. PLoS Genet (2010) 1.32
Functional oligomeric state of avian sarcoma virus integrase. J Biol Chem (2002) 1.31
Structural insights into the first incision reaction during nucleotide excision repair. EMBO J (2005) 1.30
Mitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress. J Cell Sci (2012) 1.30
Homologous recombination but not nucleotide excision repair plays a pivotal role in tolerance of DNA-protein cross-links in mammalian cells. J Biol Chem (2009) 1.29
Conceptual model of comprehensive research metrics for improved human health and environment. Environ Health Perspect (2008) 1.29
Downstream DNA sequence effects on transcription elongation. Allosteric binding of nucleoside triphosphates facilitates translocation via a ratchet motion. J Biol Chem (2003) 1.24
Transcript cleavage by Thermus thermophilus RNA polymerase. Effects of GreA and anti-GreA factors. J Biol Chem (2001) 1.24
Reduction in frataxin causes progressive accumulation of mitochondrial damage. Hum Mol Genet (2003) 1.24
Interconvertible lac repressor-DNA loops revealed by single-molecule experiments. PLoS Biol (2008) 1.23
Double-strand break formation during nucleotide excision repair of a DNA interstrand cross-link. Biochemistry (2009) 1.23
Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress. Proc Natl Acad Sci U S A (2002) 1.20
Large conformational changes in MutS during DNA scanning, mismatch recognition and repair signalling. EMBO J (2012) 1.20
Aprataxin localizes to mitochondria and preserves mitochondrial function. Proc Natl Acad Sci U S A (2011) 1.19
A minimal exonuclease domain of WRN forms a hexamer on DNA and possesses both 3'- 5' exonuclease and 5'-protruding strand endonuclease activities. Biochemistry (2002) 1.19
Initiation of repair of DNA-polypeptide cross-links by the UvrABC nuclease. Biochemistry (2005) 1.19
Asbestos induces mitochondrial DNA damage and dysfunction linked to the development of apoptosis. Am J Physiol Lung Cell Mol Physiol (2003) 1.18
Direct and indirect roles of RECQL4 in modulating base excision repair capacity. Hum Mol Genet (2009) 1.18
Apoptosis induced by persistent single-strand breaks in mitochondrial genome: critical role of EXOG (5'-EXO/endonuclease) in their repair. J Biol Chem (2011) 1.18
Inhibiting systemic autophagy during interleukin 2 immunotherapy promotes long-term tumor regression. Cancer Res (2012) 1.17
Mitochondrial and nuclear DNA defects in Saccharomyces cerevisiae with mutations in DNA polymerase gamma associated with progressive external ophthalmoplegia. Hum Mol Genet (2005) 1.16
Conserved helicase domain of human RecQ4 is required for strand annealing-independent DNA unwinding. DNA Repair (Amst) (2010) 1.16
Prokaryotic nucleotide excision repair. Cold Spring Harb Perspect Biol (2013) 1.16
Probing for DNA damage with β-hairpins: similarities in incision efficiencies of bulky DNA adducts by prokaryotic and human nucleotide excision repair systems in vitro. DNA Repair (Amst) (2011) 1.15
The involvement of human RECQL4 in DNA double-strand break repair. Aging Cell (2010) 1.15
Interactions between UvrA and UvrB: the role of UvrB's domain 2 in nucleotide excision repair. EMBO J (2004) 1.15
The mitochondrial transcription factor A functions in mitochondrial base excision repair. DNA Repair (Amst) (2010) 1.14
Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures. J Biol Chem (2004) 1.13
Analysis of DNA damage and repair in nuclear and mitochondrial DNA of animal cells using quantitative PCR. Methods Mol Biol (2012) 1.13
Oxidants and not alkylating agents induce rapid mtDNA loss and mitochondrial dysfunction. DNA Repair (Amst) (2012) 1.12
Crystal structure of Thermus aquaticus Gfh1, a Gre-factor paralog that inhibits rather than stimulates transcript cleavage. J Mol Biol (2005) 1.11
The C-terminal zinc finger of UvrA does not bind DNA directly but regulates damage-specific DNA binding. J Biol Chem (2006) 1.10
Importance of glycolysis and oxidative phosphorylation in advanced melanoma. Mol Cancer (2012) 1.10
Evidence that OGG1 glycosylase protects neurons against oxidative DNA damage and cell death under ischemic conditions. J Cereb Blood Flow Metab (2010) 1.09
Mitochondrial structure, function and dynamics are temporally controlled by c-Myc. PLoS One (2012) 1.09
Structure of the C-terminal half of UvrC reveals an RNase H endonuclease domain with an Argonaute-like catalytic triad. EMBO J (2007) 1.09
Functional characterization and atomic force microscopy of a DNA repair protein conjugated to a quantum dot. Nano Lett (2008) 1.09
Toward the assessment of scientific and public health impacts of the National Institute of Environmental Health Sciences Extramural Asthma Research Program using available data. Environ Health Perspect (2009) 1.08
Sequence context- and temperature-dependent nucleotide excision repair of a benzo[a]pyrene diol epoxide-guanine DNA adduct catalyzed by thermophilic UvrABC proteins. Biochemistry (2007) 1.08
RecQ helicases in DNA double strand break repair and telomere maintenance. Mutat Res (2011) 1.08
Analyzing the handoff of DNA from UvrA to UvrB utilizing DNA-protein photoaffinity labeling. J Biol Chem (2004) 1.07
Repair activity of base and nucleotide excision repair enzymes for guanine lesions induced by nitrosative stress. Nucleic Acids Res (2005) 1.06
Unactivated PKR exists in an open conformation capable of binding nucleotides. Biochemistry (2006) 1.06