Published in Nucleic Acids Res on November 25, 1992
Regulation of ribonuclease III processing by double-helical sequence antideterminants. Proc Natl Acad Sci U S A (1997) 2.04
Subunits of the Saccharomyces cerevisiae signal recognition particle required for its functional expression. EMBO J (1994) 1.77
A mutant hunt for defects in membrane protein assembly yields mutations affecting the bacterial signal recognition particle and Sec machinery. Proc Natl Acad Sci U S A (2000) 1.65
In vitro studies with purified components reveal signal recognition particle (SRP) and SecA/SecB as constituents of two independent protein-targeting pathways of Escherichia coli. Mol Biol Cell (1999) 1.46
The crystal structure of the signal recognition particle in complex with its receptor. Science (2011) 1.41
Important role of the tetraloop region of 4.5S RNA in SRP binding to its receptor FtsY. RNA (2001) 1.25
Structure of 4.5S RNA in the signal recognition particle of Escherichia coli as studied by enzymatic and chemical probing. RNA (1996) 1.21
Genetic screen yields mutations in genes encoding all known components of the Escherichia coli signal recognition particle pathway. J Bacteriol (2002) 1.16
A complex of the signal sequence binding protein and the SRP RNA promotes translocation of nascent proteins. EMBO J (1995) 1.14
NPInter v2.0: an updated database of ncRNA interactions. Nucleic Acids Res (2013) 1.13
Molecular evolution of SRP cycle components: functional implications. Nucleic Acids Res (1994) 1.09
A highly conserved nucleotide in the Alu domain of SRP RNA mediates translation arrest through high affinity binding to SRP9/14. Nucleic Acids Res (1997) 1.00
Domain rearrangement of SRP protein Ffh upon binding 4.5S RNA and the SRP receptor FtsY. RNA (2005) 0.98
Promiscuous targeting of polytopic membrane proteins to SecYEG or YidC by the Escherichia coli signal recognition particle. Mol Biol Cell (2011) 0.95
Functional analysis of the signal recognition particle in Escherichia coli by characterization of a temperature-sensitive ffh mutant. J Bacteriol (2002) 0.92
The heterodimeric subunit SRP9/14 of the signal recognition particle functions as permuted single polypeptide chain. Nucleic Acids Res (1994) 0.92
Effect of 4.5S RNA depletion on Escherichia coli protein synthesis and secretion. J Bacteriol (1994) 0.90
Functional interchangeability of the structurally similar tetranucleotide loops GAAA and UUCG in fission yeast signal recognition particle RNA. Proc Natl Acad Sci U S A (1993) 0.86
Saccharomyces SRP RNA secondary structures: a conserved S-domain and extended Alu-domain. RNA (2004) 0.85
Genetic and biochemical analysis of the fission yeast ribonucleoprotein particle containing a homolog of Srp54p. Nucleic Acids Res (1994) 0.79
Structural requirements of Bacillus subtilis small cytoplasmic RNA for cell growth, sporulation, and extracellular enzyme production. J Bacteriol (1994) 0.78
Characterization of conserved bases in 4.5S RNA of Escherichia coli by construction of new F' factors. J Bacteriol (2008) 0.76
Signal recognition particle and SecA cooperate during export of secretory proteins with highly hydrophobic signal sequences. PLoS One (2014) 0.75
Construction of a new family of high efficiency bacterial expression vectors: identification of cDNA clones coding for human liver proteins. EMBO J (1984) 7.60
Architecture of ribosomal RNA: constraints on the sequence of "tetra-loops". Proc Natl Acad Sci U S A (1990) 6.25
Genetic control of heat-shock protein synthesis and its bearing on growth and thermal resistance in Escherichia coli K-12. Proc Natl Acad Sci U S A (1982) 6.03
Structural features that give rise to the unusual stability of RNA hairpins containing GNRA loops. Science (1991) 6.01
Production of abnormal proteins in E. coli stimulates transcription of lon and other heat shock genes. Cell (1985) 4.96
SRP-RNA sequence alignment and secondary structure. Nucleic Acids Res (1991) 4.88
Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle. Nature (1989) 4.25
Homology of 54K protein of signal-recognition particle, docking protein and two E. coli proteins with putative GTP-binding domains. Nature (1989) 4.05
Construction and analysis of in vivo activity of E. coli promoter hybrids and promoter mutants that alter the -35 to -10 spacing. Gene (1982) 3.68
An E. coli ribonucleoprotein containing 4.5S RNA resembles mammalian signal recognition particle. Science (1990) 3.55
Photocrosslinking of the signal sequence of nascent preprolactin to the 54-kilodalton polypeptide of the signal recognition particle. Proc Natl Acad Sci U S A (1986) 3.55
Disassembly and reconstitution of signal recognition particle. Cell (1983) 3.45
The signal recognition particle in S. cerevisiae. Cell (1991) 3.24
The most abundant small cytoplasmic RNA of Saccharomyces cerevisiae has an important function required for normal cell growth. Mol Cell Biol (1989) 2.55
Nucleotide sequence and in vitro processing of a precursor molecule to Escherichia coli 4.5 S RNA. J Biol Chem (1976) 2.43
The methionine-rich domain of the 54 kd protein subunit of the signal recognition particle contains an RNA binding site and can be crosslinked to a signal sequence. EMBO J (1990) 2.35
DnaK and DnaJ heat shock proteins participate in protein export in Escherichia coli. Genes Dev (1992) 2.34
Human SRP RNA and E. coli 4.5S RNA contain a highly homologous structural domain. Cell (1988) 2.31
The 4.5 S RNA gene of Escherichia coli is essential for cell growth. J Mol Biol (1984) 2.24
E. coli 4.5S RNA is part of a ribonucleoprotein particle that has properties related to signal recognition particle. Cell (1990) 2.22
Direct probing of the interaction between the signal sequence of nascent preprolactin and the signal recognition particle by specific cross-linking. J Cell Biol (1987) 2.21
Binding sites of the 9- and 14-kilodalton heterodimeric protein subunit of the signal recognition particle (SRP) are contained exclusively in the Alu domain of SRP RNA and contain a sequence motif that is conserved in evolution. Mol Cell Biol (1991) 1.61
Loss of 4.5S RNA induces the heat shock response and lambda prophage in Escherichia coli. J Bacteriol (1990) 1.36
Recognition of a tetranucleotide loop of signal recognition particle RNA by protein SRP19. J Biol Chem (1992) 1.32
Heat-shock proteins can substitute for SecB function during protein export in Escherichia coli. EMBO J (1991) 1.31
Interaction of protein SRP19 with signal recognition particle RNA lacking individual RNA-helices. Nucleic Acids Res (1991) 1.25
Small cytoplasmic RNA of Bacillus subtilis: functional relationship with human signal recognition particle 7S RNA and Escherichia coli 4.5S RNA. J Bacteriol (1992) 1.23
Functional dissection of the signal recognition particle. Trends Biochem Sci (1988) 1.13
Genetic selection and DNA sequences of 4.5S RNA homologs. J Bacteriol (1989) 1.11
Escherichia coli 4.5S RNA gene function can be complemented by heterologous bacterial RNA genes. J Bacteriol (1990) 1.05
Random mutagenesis of Schizosaccharomyces pombe SRP RNA: lethal and conditional lesions cluster in presumptive protein binding sites. Nucleic Acids Res (1992) 1.01
Genetic analysis of Schizosaccharomyces pombe 7SL RNA: a structural motif that includes a conserved tetranucleotide loop is important for function. Proc Natl Acad Sci U S A (1989) 0.89
The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases. Cell (1997) 8.94
Ribosome synthesis in Saccharomyces cerevisiae. Annu Rev Genet (1999) 8.72
Functions of the exosome in rRNA, snoRNA and snRNA synthesis. EMBO J (1999) 5.68
The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases. Genes Dev (1999) 4.95
A yeast nucleolar protein related to mammalian fibrillarin is associated with small nucleolar RNA and is essential for viability. EMBO J (1989) 4.91
Identification of a regulated pathway for nuclear pre-mRNA turnover. Cell (2000) 4.38
Identification and functional analysis of two U3 binding sites on yeast pre-ribosomal RNA. EMBO J (1992) 4.17
The 5' end of yeast 5.8S rRNA is generated by exonucleases from an upstream cleavage site. EMBO J (1994) 4.10
Identification of a 60S preribosomal particle that is closely linked to nuclear export. Mol Cell (2001) 3.95
Dob1p (Mtr4p) is a putative ATP-dependent RNA helicase required for the 3' end formation of 5.8S rRNA in Saccharomyces cerevisiae. EMBO J (1998) 3.88
GAR1 is an essential small nucleolar RNP protein required for pre-rRNA processing in yeast. EMBO J (1992) 3.72
The box H + ACA snoRNAs carry Cbf5p, the putative rRNA pseudouridine synthase. Genes Dev (1998) 3.60
Nuclear export of 60s ribosomal subunits depends on Xpo1p and requires a nuclear export sequence-containing factor, Nmd3p, that associates with the large subunit protein Rpl10p. Mol Cell Biol (2001) 3.60
Fungal small nuclear ribonucleoproteins share properties with plant and vertebrate U-snRNPs. EMBO J (1987) 3.50
Mammalian nuclei contain foci which are highly enriched in components of the pre-mRNA splicing machinery. EMBO J (1991) 3.49
Yeast snR30 is a small nucleolar RNA required for 18S rRNA synthesis. Mol Cell Biol (1993) 3.47
Processing of pre-ribosomal RNA in Saccharomyces cerevisiae. Yeast (1995) 3.39
Accurate processing of a eukaryotic precursor ribosomal RNA by ribonuclease MRP in vitro. Science (1996) 3.35
One-step PCR mediated strategy for the construction of conditionally expressed and epitope tagged yeast proteins. Nucleic Acids Res (1996) 3.28
The POP1 gene encodes a protein component common to the RNase MRP and RNase P ribonucleoproteins. Genes Dev (1994) 3.12
Base pairing between U3 and the pre-ribosomal RNA is required for 18S rRNA synthesis. EMBO J (1995) 3.08
mRNA stability in eukaryotes. Curr Opin Genet Dev (2000) 3.01
Nucleolar KKE/D repeat proteins Nop56p and Nop58p interact with Nop1p and are required for ribosome biogenesis. Mol Cell Biol (1997) 2.95
The 18S rRNA dimethylase Dim1p is required for pre-ribosomal RNA processing in yeast. Genes Dev (1995) 2.92
Nuclear pore proteins are involved in the biogenesis of functional tRNA. EMBO J (1996) 2.90
The 3' end of yeast 5.8S rRNA is generated by an exonuclease processing mechanism. Genes Dev (1996) 2.82
Processing of the precursors to small nucleolar RNAs and rRNAs requires common components. Mol Cell Biol (1998) 2.80
A U3 snoRNP protein with homology to splicing factor PRP4 and G beta domains is required for ribosomal RNA processing. EMBO J (1993) 2.71
YidC, the Escherichia coli homologue of mitochondrial Oxa1p, is a component of the Sec translocase. EMBO J (2000) 2.70
Characterization of an SNR gene locus in Saccharomyces cerevisiae that specifies both dispensible and essential small nuclear RNAs. Mol Cell Biol (1988) 2.65
Synthetic lethality with fibrillarin identifies NOP77p, a nucleolar protein required for pre-rRNA processing and modification. EMBO J (1994) 2.53
Crystal structure of the NG domain from the signal-recognition particle receptor FtsY. Nature (1997) 2.51
Nop58p is a common component of the box C+D snoRNPs that is required for snoRNA stability. RNA (1999) 2.48
Degradation of ribosomal RNA precursors by the exosome. Nucleic Acids Res (2000) 2.47
RRP5 is required for formation of both 18S and 5.8S rRNA in yeast. EMBO J (1996) 2.41
Yeast contains small nuclear RNAs encoded by single copy genes. Cell (1983) 2.40
Evolutionary conservation of the human nucleolar protein fibrillarin and its functional expression in yeast. J Cell Biol (1991) 2.39
Early events in preprotein recognition in E. coli: interaction of SRP and trigger factor with nascent polypeptides. EMBO J (1995) 2.38
Maturation and intranuclear transport of pre-ribosomes requires Noc proteins. Cell (2001) 2.38
A novel in vivo assay reveals inhibition of ribosomal nuclear export in ran-cycle and nucleoporin mutants. J Cell Biol (1999) 2.37
Birth of the snoRNPs: the evolution of RNase MRP and the eukaryotic pre-rRNA-processing system. Trends Biochem Sci (1995) 2.36
The Escherichia coli SRP and SecB targeting pathways converge at the translocon. EMBO J (1998) 2.35
E. coli 4.5S RNA is part of a ribonucleoprotein particle that has properties related to signal recognition particle. Cell (1990) 2.22
Lithium toxicity in yeast is due to the inhibition of RNA processing enzymes. EMBO J (1997) 2.18
Deletion of a yeast small nuclear RNA gene impairs growth. EMBO J (1985) 2.17
Birth of the snoRNPs: the evolution of the modification-guide snoRNAs. Trends Biochem Sci (1998) 2.14
Like attracts like: getting RNA processing together in the nucleus. Science (2000) 2.13
Yeast Rnt1p is required for cleavage of the pre-ribosomal RNA in the 3' ETS but not the 5' ETS. RNA (1999) 2.11
Synthesis and assembly of the box C+D small nucleolar RNPs. Mol Cell Biol (2000) 2.11
Signal-sequence recognition by an Escherichia coli ribonucleoprotein complex. Nature (1992) 2.02
mRNA turnover. Curr Opin Cell Biol (2001) 1.98
A U4-like small nuclear RNA is dispensable in yeast. Cell (1983) 1.96
Base pairing between U3 small nucleolar RNA and the 5' end of 18S rRNA is required for pre-rRNA processing. Mol Cell Biol (1999) 1.95
Musing on the structural organization of the exosome complex. Nat Struct Biol (2000) 1.92
Precursors to the U3 small nucleolar RNA lack small nucleolar RNP proteins but are stabilized by La binding. Mol Cell Biol (2000) 1.90
Mex67p mediates nuclear export of a variety of RNA polymerase II transcripts. J Biol Chem (2000) 1.90
NOP3 is an essential yeast protein which is required for pre-rRNA processing. J Cell Biol (1992) 1.89
Assembly of a cytoplasmic membrane protein in Escherichia coli is dependent on the signal recognition particle. FEBS Lett (1996) 1.89
Yeast 18S rRNA dimethylase Dim1p: a quality control mechanism in ribosome synthesis? Mol Cell Biol (1998) 1.86
Pop3p is essential for the activity of the RNase MRP and RNase P ribonucleoproteins in vivo. EMBO J (1997) 1.85
Nascent membrane and presecretory proteins synthesized in Escherichia coli associate with signal recognition particle and trigger factor. Mol Microbiol (1997) 1.85
7SL RNA from Schizosaccharomyces pombe is encoded by a single copy essential gene. EMBO J (1988) 1.78
Rok1p is a putative RNA helicase required for rRNA processing. Mol Cell Biol (1997) 1.75
Three novel components of the human exosome. J Biol Chem (2000) 1.72
A nuclear AAA-type ATPase (Rix7p) is required for biogenesis and nuclear export of 60S ribosomal subunits. EMBO J (2001) 1.69
Small nuclear RNAs in messenger RNA and ribosomal RNA processing. FASEB J (1993) 1.65
Mutational analysis of an essential binding site for the U3 snoRNA in the 5' external transcribed spacer of yeast pre-rRNA. Nucleic Acids Res (1994) 1.63
Differential use of the signal recognition particle translocase targeting pathway for inner membrane protein assembly in Escherichia coli. Proc Natl Acad Sci U S A (1998) 1.62
Characterization of a hemoglobin protease secreted by the pathogenic Escherichia coli strain EB1. J Exp Med (1998) 1.60
Nitrogen metabolite signalling involves the C-terminus and the GATA domain of the Aspergillus transcription factor AREA and the 3' untranslated region of its mRNA. EMBO J (1996) 1.58
Sec-dependent membrane protein insertion: sequential interaction of nascent FtsQ with SecY and YidC. EMBO Rep (2001) 1.57
Anionic phospholipids are involved in membrane association of FtsY and stimulate its GTPase activity. EMBO J (2000) 1.56
Genetic and physical interactions involving the yeast nuclear cap-binding complex. Mol Cell Biol (1999) 1.56
The function and synthesis of ribosomes. Nat Rev Mol Cell Biol (2001) 1.53
Dhr1p, a putative DEAH-box RNA helicase, is associated with the box C+D snoRNP U3. Mol Cell Biol (2000) 1.51
A conserved function of YidC in the biogenesis of respiratory chain complexes. Proc Natl Acad Sci U S A (2003) 1.48
Box C/D small nucleolar RNA trafficking involves small nucleolar RNP proteins, nucleolar factors and a novel nuclear domain. EMBO J (2001) 1.47
Spb4p, an essential putative RNA helicase, is required for a late step in the assembly of 60S ribosomal subunits in Saccharomyces cerevisiae. RNA (1998) 1.45
Functional analysis of Rrp7p, an essential yeast protein involved in pre-rRNA processing and ribosome assembly. Mol Cell Biol (1997) 1.44
Yeast nucleoporin mutants are defective in pre-tRNA splicing. Mol Cell Biol (1996) 1.43
The role of the 3' external transcribed spacer in yeast pre-rRNA processing. J Mol Biol (1998) 1.39
Molecular characterization of Escherichia coli FtsE and FtsX. Mol Microbiol (1999) 1.39
Nascent Lep inserts into the Escherichia coli inner membrane in the vicinity of YidC, SecY and SecA. FEBS Lett (2000) 1.36
SecA is not required for signal recognition particle-mediated targeting and initial membrane insertion of a nascent inner membrane protein. J Biol Chem (1999) 1.36
Processing of the yeast pre-rRNA at sites A(2) and A(3) is linked. RNA (1996) 1.33
Two distinct recognition signals define the site of endonucleolytic cleavage at the 5'-end of yeast 18S rRNA. EMBO J (1995) 1.32
Membrane association of FtsY, the E. coli SRP receptor. FEBS Lett (1997) 1.31
Trans-acting factors in yeast pre-rRNA and pre-snoRNA processing. Biochem Cell Biol (1996) 1.29
Reconstitution of Sec-dependent membrane protein insertion: nascent FtsQ interacts with YidC in a SecYEG-dependent manner. EMBO Rep (2001) 1.25
Important role of the tetraloop region of 4.5S RNA in SRP binding to its receptor FtsY. RNA (2001) 1.25
The early interaction of the outer membrane protein phoe with the periplasmic chaperone Skp occurs at the cytoplasmic membrane. J Biol Chem (2001) 1.22
Yeast Nop3p has structural and functional similarities to mammalian pre-mRNA binding proteins. Eur J Cell Biol (1995) 1.22
Subcloning of the cloacin DF13/aerobactin receptor protein and identification of a pColV-K30-determined polypeptide involved in ferric-aerobactin uptake. J Bacteriol (1983) 1.16
The E. coli SRP: preferences of a targeting factor. FEBS Lett (1997) 1.14
Chloroplast SRP54 interacts with a specific subset of thylakoid precursor proteins. J Biol Chem (1997) 1.12
Growing up in a dangerous environment: a network of multiple targeting and folding pathways for nascent polypeptides in the cytosol. Trends Cell Biol (1996) 1.11
Production of monoclonal antibodies defining guinea pig T-cell surface markers and a strain 13 Ia-like antigen: the value of immunohistological screening. Hybridoma (1985) 1.11
Biogenesis of inner membrane proteins in Escherichia coli. Mol Microbiol (2001) 1.11
Effects of divalent cations and of phospholipase A activity on excretion of cloacin DF13 and lysis of host cells. J Gen Microbiol (1986) 1.08
Evidence for coupling of membrane targeting and function of the signal recognition particle (SRP) receptor FtsY. EMBO Rep (2001) 1.08