Human population structure and genetic association studies.

PubWeight™: 2.00‹?› | Rank: Top 2%

🔗 View Article (PMID 12831322)

Published in Pharmacogenomics on July 01, 2003

Authors

Elad Ziv1, Esteban González Burchard

Author Affiliations

1: Division of General Internal Medicine and Division of Pulmonary Medicine, Department of Medicine, University of California, San Francisco, CA 94115, USA. eziv@itsa.ucsf.edu

Articles citing this

Informativeness of genetic markers for inference of ancestry. Am J Hum Genet (2003) 6.90

Estimating local ancestry in admixed populations. Am J Hum Genet (2008) 5.90

Genome-wide association studies in diverse populations. Nat Rev Genet (2010) 4.68

Population stratification confounds genetic association studies among Latinos. Hum Genet (2005) 3.19

PCA-correlated SNPs for structure identification in worldwide human populations. PLoS Genet (2007) 2.36

Low levels of genetic divergence across geographically and linguistically diverse populations from India. PLoS Genet (2006) 2.26

Comparison of three methods to estimate genetic ancestry and control for stratification in genetic association studies among admixed populations. Hum Genet (2005) 2.19

Review and evaluation of methods correcting for population stratification with a focus on underlying statistical principles. Hum Hered (2008) 1.92

A general population-genetic model for the production by population structure of spurious genotype-phenotype associations in discrete, admixed or spatially distributed populations. Genetics (2006) 1.92

Genetic ancestry, population sub-structure, and cardiovascular disease-related traits among African-American participants in the CARDIA Study. Hum Genet (2007) 1.91

Population admixture associated with disease prevalence in the Boston Puerto Rican health study. Hum Genet (2008) 1.89

A comprehensive literature review of haplotyping software and methods for use with unrelated individuals. Hum Genomics (2005) 1.84

Genome-wide screen for asthma in Puerto Ricans: evidence for association with 5q23 region. Hum Genet (2008) 1.81

Proportioning whole-genome single-nucleotide-polymorphism diversity for the identification of geographic population structure and genetic ancestry. Am J Hum Genet (2006) 1.76

Chromogranin A polymorphisms are associated with hypertensive renal disease. J Am Soc Nephrol (2008) 1.68

Tracing sub-structure in the European American population with PCA-informative markers. PLoS Genet (2008) 1.56

Beta 2-adrenergic receptor polymorphisms: pharmacogenetic response to bronchodilator among African American asthmatics. Hum Genet (2006) 1.43

Genetic ancestry and risk factors for breast cancer among Latinas in the San Francisco Bay Area. Cancer Epidemiol Biomarkers Prev (2006) 1.30

Admixture-matched case-control study: a practical approach for genetic association studies in admixed populations. Hum Genet (2005) 1.27

Genetic ancestry modifies pharmacogenetic gene-gene interaction for asthma. Pharmacogenet Genomics (2009) 1.24

African ancestry is associated with risk of asthma and high total serum IgE in a population from the Caribbean Coast of Colombia. Hum Genet (2009) 1.24

Dissecting complex diseases in complex populations: asthma in latino americans. Proc Am Thorac Soc (2007) 1.21

Fine-scale patterns of population stratification confound rare variant association tests. PLoS One (2013) 1.18

Power consequences of linkage disequilibrium variation between populations. Genet Epidemiol (2009) 1.08

Correcting for measurement error in individual ancestry estimates in structured association tests. Genetics (2007) 1.04

Genetic heterogeneity of self-reported ancestry groups in an admixed Brazilian population. J Epidemiol (2011) 0.99

African ancestry is a risk factor for asthma and high total IgE levels in African admixed populations. Genet Epidemiol (2013) 0.97

Multiple imputation to correct for measurement error in admixture estimates in genetic structured association testing. Hum Hered (2009) 0.94

African and non-African admixture components in African Americans and an African Caribbean population. Genet Epidemiol (2010) 0.93

Population stratification in a case-control study of brain arteriovenous malformation in Latinos. Neuroepidemiology (2008) 0.89

Comparison of statistical methods for estimating genetic admixture in a lung cancer study of African Americans and Latinos. Am J Epidemiol (2008) 0.89

Genetic ancestry, self-reported race and ethnicity in African Americans and European Americans in the PCaP cohort. PLoS One (2012) 0.89

Ancestry informative marker set for han chinese population. G3 (Bethesda) (2012) 0.87

The Association of African Ancestry and elevated creatinine in the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Am J Nephrol (2009) 0.86

Genetic susceptibility to methylmercury developmental neurotoxicity matters. Front Genet (2013) 0.85

Associations of PON1 and genetic ancestry with obesity in early childhood. PLoS One (2013) 0.80

Recent progress in the genetics and epigenetics of paraoxonase: why it is relevant to children's environmental health. Curr Opin Pediatr (2015) 0.79

What are our AIMs? Interdisciplinary Perspectives on the Use of Ancestry Estimation in Disease Research. AJOB Prim Res (2012) 0.79

Windfalls and pitfalls: Applications of population genetics to the search for disease genes. Evol Med Public Health (2013) 0.78

Human population genetic structure detected by pain-related mu opioid receptor gene polymorphisms. Genet Mol Biol (2015) 0.77

Population analysis of vitamin D receptor polymorphisms and the role of genetic ancestry in an admixed population. Genet Mol Biol (2011) 0.77

TagSNP transferability and relative loss of variability prediction from HapMap to an admixed population. J Biomed Sci (2009) 0.76

European American stratification in ovarian cancer case control data: the utility of genome-wide data for inferring ancestry. PLoS One (2012) 0.76

Population analysis of xenobiotic metabolizing genes in South Brazilian Euro and Afro-descendants. Genet Mol Biol (2009) 0.76

Genome Wide Association Studies of Chemotherapeutic Toxicities: Genomics of Inequality. Clin Cancer Res (2017) 0.75

Articles by these authors

Genomics for the world. Nature (2011) 3.68

Genetic ancestry in lung-function predictions. N Engl J Med (2010) 3.30

Genetic admixture and asthma-related phenotypes in Mexican American and Puerto Rican asthmatics. Genet Epidemiol (2005) 3.03

Recent genetic selection in the ancestral admixture of Puerto Ricans. Am J Hum Genet (2007) 2.72

Pharmacogenetic differences in response to albuterol between Puerto Ricans and Mexicans with asthma. Am J Respir Crit Care Med (2004) 2.62

The 1000 Genomes Project: new opportunities for research and social challenges. Genome Med (2010) 2.43

Population structure, admixture, and aging-related phenotypes in African American adults: the Cardiovascular Health Study. Am J Hum Genet (2005) 2.41

Comparison of three methods to estimate genetic ancestry and control for stratification in genetic association studies among admixed populations. Hum Genet (2005) 2.19

ORMDL3 gene is associated with asthma in three ethnically diverse populations. Am J Respir Crit Care Med (2008) 2.18

Population admixture associated with disease prevalence in the Boston Puerto Rican health study. Hum Genet (2008) 1.89

Genome-wide screen for asthma in Puerto Ricans: evidence for association with 5q23 region. Hum Genet (2008) 1.81

Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations. J Natl Cancer Inst (2013) 1.81

Reconstructing the population genetic history of the Caribbean. PLoS Genet (2013) 1.68

Genetic ancestry and risk of breast cancer among U.S. Latinas. Cancer Res (2008) 1.58

Ethnic-specific differences in bronchodilator responsiveness among African Americans, Puerto Ricans, and Mexicans with asthma. J Asthma (2007) 1.57

Chitotriosidase is the primary active chitinase in the human lung and is modulated by genotype and smoking habit. J Allergy Clin Immunol (2008) 1.56

History shaped the geographic distribution of genomic admixture on the island of Puerto Rico. PLoS One (2011) 1.50

Ancestry-environment interactions and asthma risk among Puerto Ricans. Am J Respir Crit Care Med (2006) 1.42

CD14 tobacco gene-environment interaction modifies asthma severity and immunoglobulin E levels in Latinos with asthma. Am J Respir Crit Care Med (2005) 1.34

Admixture-matched case-control study: a practical approach for genetic association studies in admixed populations. Hum Genet (2005) 1.27

Genetic ancestry modifies pharmacogenetic gene-gene interaction for asthma. Pharmacogenet Genomics (2009) 1.24

Inhaled corticosteroids and augmented bronchodilator responsiveness in Latino and African American asthmatic patients. Ann Allergy Asthma Immunol (2008) 1.23

Dissecting complex diseases in complex populations: asthma in latino americans. Proc Am Thorac Soc (2007) 1.21

Heterogeneity in genetic admixture across different regions of Argentina. PLoS One (2012) 1.20

Common variants in interleukin-1-Beta gene are associated with intracranial hemorrhage and susceptibility to brain arteriovenous malformation. Cerebrovasc Dis (2008) 1.17

An african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity. Hum Mol Genet (2008) 1.15

Admixture mapping identifies a locus on 6q25 associated with breast cancer risk in US Latinas. Hum Mol Genet (2012) 1.11

Ethnicity-specific gene-gene interaction between IL-13 and IL-4Ralpha among African Americans with asthma. Am J Respir Crit Care Med (2007) 1.10

Identification of KIF3A as a novel candidate gene for childhood asthma using RNA expression and population allelic frequencies differences. PLoS One (2011) 1.10

Race, ethnicity and social class and the complex etiologies of asthma. Pharmacogenomics (2008) 1.09

Association between IgE levels and asthma severity among African American, Mexican, and Puerto Rican patients with asthma. J Allergy Clin Immunol (2007) 1.02

African ancestry, socioeconomic status, and kidney function in elderly African Americans: a genetic admixture analysis. J Am Soc Nephrol (2006) 1.02

Melanesian blond hair is caused by an amino acid change in TYRP1. Science (2012) 1.01

Genetic ancestry and its association with asthma exacerbations among African American subjects with asthma. J Allergy Clin Immunol (2012) 0.97

Latino populations: a unique opportunity for epidemiological research of asthma. Paediatr Perinat Epidemiol (2007) 0.90

Augmentation of bronchodilator responsiveness by leukotriene modifiers in Puerto Rican and Mexican children. Ann Allergy Asthma Immunol (2009) 0.88

Furthering the link between the sarcomere and primary cardiomyopathies: restrictive cardiomyopathy associated with multiple mutations in genes previously associated with hypertrophic or dilated cardiomyopathy. Am J Med Genet A (2011) 0.84

Pharmacogenetic response to albuterol among asthmatics. Pharmacogenomics (2008) 0.83

ALOX5AP and LTA4H polymorphisms modify augmentation of bronchodilator responsiveness by leukotriene modifiers in Latinos. J Allergy Clin Immunol (2010) 0.81

Ethnic variability in persistent asthma after in utero tobacco exposure. Pediatrics (2011) 0.80

Birthplace and mortality among insured Latinos: the paradox revisited. Ethn Dis (2009) 0.79

The PTGDR gene is not associated with asthma in 3 ethnically diverse populations. J Allergy Clin Immunol (2006) 0.77