Published in J Biol Chem on July 02, 2003
Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing. Nat Cell Biol (2008) 2.93
Prp8 protein: at the heart of the spliceosome. RNA (2005) 2.89
RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells. Proc Natl Acad Sci U S A (2005) 2.59
Inhibition of Wnt signaling by the osteoblast-specific transcription factor Osterix. Proc Natl Acad Sci U S A (2008) 1.86
A human splicing factor, SKIP, associates with P-TEFb and enhances transcription elongation by HIV-1 Tat. Genes Dev (2005) 1.66
Regulation of cyclin D1 RNA stability by SNIP1. Cancer Res (2008) 1.33
Transcriptional co-activator protein p100 interacts with snRNP proteins and facilitates the assembly of the spliceosome. Nucleic Acids Res (2007) 1.31
A subset of nuclear receptor coregulators act as coupling proteins during synthesis and maturation of RNA transcripts. Mol Cell Biol (2005) 1.22
SKIP is a component of the spliceosome linking alternative splicing and the circadian clock in Arabidopsis. Plant Cell (2012) 1.21
STAMP, a novel predicted factor assisting TIF2 actions in glucocorticoid receptor-mediated induction and repression. Mol Cell Biol (2006) 1.18
SKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicing. Genes Dev (2011) 1.10
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Osteoblast-specific transcription factor Osterix (Osx) is an upstream regulator of Satb2 during bone formation. J Biol Chem (2011) 1.09
Genome-wide association study of prognosis in advanced non-small cell lung cancer patients receiving platinum-based chemotherapy. Clin Cancer Res (2012) 1.05
Transcriptional regulation of Vascular Endothelial Growth Factor (VEGF) by osteoblast-specific transcription factor Osterix (Osx) in osteoblasts. J Biol Chem (2011) 1.03
Identification of novel pathway partners of p68 and p72 RNA helicases through Oncomine meta-analysis. BMC Genomics (2007) 1.01
Spliceosome database: a tool for tracking components of the spliceosome. Nucleic Acids Res (2012) 1.01
Sclerostin is a direct target of osteoblast-specific transcription factor osterix. Biochem Biophys Res Commun (2010) 0.98
Synergistic inhibition of Wnt pathway by HIF-1α and osteoblast-specific transcription factor osterix (Osx) in osteoblasts. PLoS One (2012) 0.97
Functioning of the Drosophila Wilms'-tumor-1-associated protein homolog, Fl(2)d, in Sex-lethal-dependent alternative splicing. Genetics (2008) 0.97
Proteomic analysis of native hepatocyte nuclear factor-4α (HNF4α) isoforms, phosphorylation status, and interactive cofactors. J Biol Chem (2010) 0.96
Cofactor of BRCA1 modulates androgen-dependent transcription and alternative splicing. J Steroid Biochem Mol Biol (2007) 0.95
Functional role of transcriptional factor TBX5 in pre-mRNA splicing and Holt-Oram syndrome via association with SC35. J Biol Chem (2009) 0.95
Osteoblast-specific transcription factor Osterix increases vitamin D receptor gene expression in osteoblasts. PLoS One (2011) 0.94
SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre-mRNAs. EMBO J (2014) 0.91
A large intrinsically disordered region in SKIP and its disorder-order transition induced by PPIL1 binding revealed by NMR. J Biol Chem (2009) 0.90
HIF-1α inhibits Wnt signaling pathway by activating Sost expression in osteoblasts. PLoS One (2013) 0.88
Post-translational modifications of the progesterone receptors. J Steroid Biochem Mol Biol (2013) 0.88
Vitamin D and the RNA transcriptome: more than mRNA regulation. Front Physiol (2014) 0.88
A siRNA-based screen for genes involved in chromosome end protection. PLoS One (2011) 0.86
Matrix metalloproteinase 13 (MMP13) is a direct target of osteoblast-specific transcription factor osterix (Osx) in osteoblasts. PLoS One (2012) 0.86
Corepressor CtBP and nuclear speckle protein Pnn/DRS differentially modulate transcription and splicing of the E-cadherin gene. Mol Cell Biol (2007) 0.86
Evolution of Na,K-ATPase beta m-subunit into a coregulator of transcription in placental mammals. Proc Natl Acad Sci U S A (2007) 0.84
Xenopus skip modulates Wnt/beta-catenin signaling and functions in neural crest induction. J Biol Chem (2010) 0.84
Ski-interacting protein (SKIP) interacts with androgen receptor in the nucleus and modulates androgen-dependent transcription. BMC Biochem (2013) 0.83
Characterization of Dkk1 gene regulation by the osteoblast-specific transcription factor Osx. Biochem Biophys Res Commun (2012) 0.83
Vitamin D resistance and colon cancer prevention. Carcinogenesis (2011) 0.83
An architectural perspective of vitamin D responsiveness. Arch Biochem Biophys (2007) 0.83
Molecular determinants for small Maf protein control of platelet production. Mol Cell Biol (2010) 0.80
Discovery of novel vitamin D receptor interacting proteins that modulate 1,25-dihydroxyvitamin D3 signaling. J Steroid Biochem Mol Biol (2012) 0.80
Multiple structurally distinct ERα mRNA variants in zebrafish are differentially expressed by tissue type, stage of development and estrogen exposure. Gen Comp Endocrinol (2013) 0.80
Role of precursor mRNA splicing in nutrient-induced alterations in gene expression and metabolism. J Nutr (2015) 0.79
1alpha,25-dihydroxy vitamin D(3) induces nuclear matrix association of the 1alpha,25-dihydroxy vitamin D(3) receptor in osteoblasts independently of its ability to bind DNA. J Cell Physiol (2010) 0.79
Algorithm to identify frequent coupled modules from two-layered network series: application to study transcription and splicing coupling. J Comput Biol (2012) 0.79
Multiple levels of epigenetic control for bone biology and pathology. Bone (2015) 0.78
1,25-Dihydroxyvitamin D3 activates MMP13 gene expression in chondrocytes through p38 MARK pathway. Int J Biol Sci (2013) 0.78
Vitamin D and alternative splicing of RNA. J Steroid Biochem Mol Biol (2014) 0.78
COX2 is involved in hypoxia-induced TNF-α expression in osteoblast. Sci Rep (2015) 0.77
Recruitment and subnuclear distribution of the regulatory machinery during 1alpha,25-dihydroxy vitamin D3-mediated transcriptional upregulation in osteoblasts. J Steroid Biochem Mol Biol (2010) 0.76
Inhibition of SNW1 association with spliceosomal proteins promotes apoptosis in breast cancer cells. Cancer Med (2014) 0.76
Canonical WNT signaling promotes osteogenesis by directly stimulating Runx2 gene expression. J Biol Chem (2005) 3.97
Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation. J Biol Chem (2009) 3.62
Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase. J Cell Physiol (2006) 3.32
A microRNA signature for a BMP2-induced osteoblast lineage commitment program. Proc Natl Acad Sci U S A (2008) 3.29
Networks and hubs for the transcriptional control of osteoblastogenesis. Rev Endocr Metab Disord (2006) 3.25
The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice. Mol Endocrinol (2004) 3.09
MicroRNAs 221 and 222 bypass quiescence and compromise cell survival. Cancer Res (2008) 2.97
Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors. Crit Rev Eukaryot Gene Expr (2004) 2.81
Primary mouse embryonic fibroblasts: a model of mesenchymal cartilage formation. J Cell Physiol (2004) 2.59
miRNA signatures associate with pathogenesis and progression of osteosarcoma. Cancer Res (2012) 2.52
Targeted deletion of Wwox reveals a tumor suppressor function. Proc Natl Acad Sci U S A (2007) 2.37
Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter. Mol Cell Biol (2002) 2.35
A network connecting Runx2, SATB2, and the miR-23a~27a~24-2 cluster regulates the osteoblast differentiation program. Proc Natl Acad Sci U S A (2010) 2.29
Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2. Nature (2007) 2.28
Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling. J Cell Biol (2006) 2.27
CCAAT/enhancer-binding proteins (C/EBP) beta and delta activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression. J Biol Chem (2001) 2.27
Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression. Oncogene (2004) 2.25
Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts. Cancer Res (2003) 2.20
The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion. Mol Cell Biol (2005) 2.18
Vitamin D: more than a "bone-a-fide" hormone. Mol Endocrinol (2003) 2.16
BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network. J Biol Chem (2006) 2.15
Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription. EMBO J (2004) 2.12
Inactivation of the vitamin D receptor enhances susceptibility of murine skin to UV-induced tumorigenesis. J Invest Dermatol (2008) 2.08
A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2. Proc Natl Acad Sci U S A (2011) 2.05
MicroRNA control of bone formation and homeostasis. Nat Rev Endocrinol (2012) 2.05
Dlx3 transcriptional regulation of osteoblast differentiation: temporal recruitment of Msx2, Dlx3, and Dlx5 homeodomain proteins to chromatin of the osteocalcin gene. Mol Cell Biol (2004) 1.99
Expression of the osteoblast differentiation factor RUNX2 (Cbfa1/AML3/Pebp2alpha A) is inhibited by tumor necrosis factor-alpha. J Biol Chem (2001) 1.99
The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts. J Biol Chem (2005) 1.93
Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2. Proc Natl Acad Sci U S A (2007) 1.91
Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal. J Biol Chem (2008) 1.84
Expression profile of osteoblast lineage at defined stages of differentiation. J Biol Chem (2005) 1.83
Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo. Proc Natl Acad Sci U S A (2005) 1.83
Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice. J Clin Invest (2008) 1.81
Mitotic bookmarking of genes: a novel dimension to epigenetic control. Nat Rev Genet (2010) 1.76
Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription. J Cell Physiol (2005) 1.70
Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity. Mol Cell Biol (2003) 1.69
The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism. J Biol Chem (2008) 1.67
HOXA10 controls osteoblastogenesis by directly activating bone regulatory and phenotypic genes. Mol Cell Biol (2007) 1.67
Nuclear microenvironments in biological control and cancer. Nat Rev Cancer (2007) 1.65
Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells. Cancer Res (2008) 1.63
Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells. Cancer Res (2003) 1.57