Published in Structure on July 01, 2003
Visualizing the ATPase cycle in a protein disaggregating machine: structural basis for substrate binding by ClpB. Mol Cell (2007) 1.82
Allosteric modulation of Ras positions Q61 for a direct role in catalysis. Proc Natl Acad Sci U S A (2010) 1.62
Transformation efficiency of RasQ61 mutants linked to structural features of the switch regions in the presence of Raf. Structure (2007) 1.26
Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders. Hum Mutat (2010) 1.24
Analysis of binding site hot spots on the surface of Ras GTPase. J Mol Biol (2011) 1.22
Potent non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase complex. J Med Chem (2008) 1.03
Allosteric modulation of Ras-GTP is linked to signal transduction through RAF kinase. J Biol Chem (2010) 0.98
Protein flexibility in docking and surface mapping. Q Rev Biophys (2012) 0.96
Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding. FASEB J (2015) 0.90
Minimizing frustration by folding in an aqueous environment. Arch Biochem Biophys (2007) 0.80
Plasma membrane regulates Ras signaling networks. Cell Logist (2016) 0.76
Reverse screening approach to identify potential anti-cancer targets of dipyridamole. Am J Transl Res (2016) 0.75
A comprehensive survey of Ras mutations in cancer. Cancer Res (2012) 3.67
Fragment-based identification of druggable 'hot spots' of proteins using Fourier domain correlation techniques. Bioinformatics (2009) 3.00
Allosteric modulation of Ras positions Q61 for a direct role in catalysis. Proc Natl Acad Sci U S A (2010) 1.62
A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis. Biochem J (2009) 1.33
Transformation efficiency of RasQ61 mutants linked to structural features of the switch regions in the presence of Raf. Structure (2007) 1.26
Analysis of binding site hot spots on the surface of Ras GTPase. J Mol Biol (2011) 1.22
Role of loop bundle hydrogen bonds in the maturation and activity of (Pro)caspase-3. Biochemistry (2006) 1.12
Structural mechanism of oxidative regulation of the phosphatase Cdc25B via an intramolecular disulfide bond. Biochemistry (2005) 1.03
Crystal structures of Ral-GppNHp and Ral-GDP reveal two binding sites that are also present in Ras and Rap. Structure (2004) 0.99
Allosteric modulation of Ras-GTP is linked to signal transduction through RAF kinase. J Biol Chem (2010) 0.98
Multiple solvent crystal structures of ribonuclease A: an assessment of the method. Proteins (2009) 0.91
'Pathway drug cocktail': targeting Ras signaling based on structural pathways. Trends Mol Med (2013) 0.89
Different modes of binding of mono-, di-, and trihalogenated phenols to the hemoglobin dehaloperoxidase from Amphitrite ornata. Biochemistry (2009) 0.88
Pirin is an iron-dependent redox regulator of NF-κB. Proc Natl Acad Sci U S A (2013) 0.86
Distal histidine conformational flexibility in dehaloperoxidase from Amphitrite ornata. Acta Crystallogr D Biol Crystallogr (2008) 0.86
Allosteric modulation of caspase 3 through mutagenesis. Biosci Rep (2012) 0.84
Rapid folding and unfolding of Apaf-1 CARD. J Mol Biol (2007) 0.83
Shift in the equilibrium between on and off states of the allosteric switch in Ras-GppNHp affected by small molecules and bulk solvent composition. Biochemistry (2012) 0.82
Internal binding of halogenated phenols in dehaloperoxidase-hemoglobin inhibits peroxidase function. Biophys J (2010) 0.81
Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3. Arch Biochem Biophys (2011) 0.80
Structural and kinetic study of an internal substrate binding site in dehaloperoxidase-hemoglobin A from Amphitrite ornata. Biochemistry (2013) 0.79
Comparative analysis of the 15.5kD box C/D snoRNP core protein in the primitive eukaryote Giardia lamblia reveals unique structural and functional features. Biochemistry (2011) 0.77
Functional consequences of the creation of an Asp-His-Fe triad in a 3/3 globin. Biochemistry (2011) 0.77
The role of the distal histidine in H2O2 activation and heme protection in both peroxidase and globin functions. J Phys Chem B (2012) 0.76
Structurally conserved Nop56/58 N-terminal domain facilitates archaeal box C/D ribonucleoprotein-guided methyltransferase activity. J Biol Chem (2012) 0.75
A model for the flexibility of the distal histidine in dehaloperoxidase-hemoglobin A based on X-ray crystal structures of the carbon monoxide adduct. Biochemistry (2014) 0.75
Commentary: Biochemistry and molecular biology educators launch national network. Biochem Mol Biol Educ (2010) 0.75