Published in J Biol Chem on July 03, 2003
FRET detection of cellular alpha4-integrin conformational activation. Biophys J (2003) 1.88
Mobilization of hematopoietic stem and progenitor cells using inhibitors of CXCR4 and VLA-4. Leukemia (2011) 1.44
B-cell activation by membrane-bound antigens is facilitated by the interaction of VLA-4 with VCAM-1. EMBO J (2006) 1.43
Very late antigen-4 function of myeloblasts correlates with improved overall survival for patients with acute myeloid leukemia. Blood (2008) 1.20
Real-time analysis of conformation-sensitive antibody binding provides new insights into integrin conformational regulation. J Biol Chem (2009) 1.14
Molecular basis for the dynamic strength of the integrin alpha4beta1/VCAM-1 interaction. Biophys J (2004) 1.14
Crosstalk between CXCR4/stromal derived factor-1 and VLA-4/VCAM-1 pathways regulates neutrophil retention in the bone marrow. J Immunol (2009) 1.13
Galphas-coupled receptor signaling actively down-regulates alpha4beta1-integrin affinity: a possible mechanism for cell de-adhesion. BMC Immunol (2008) 0.99
Relationship between molecular and cellular dissociation rates for VLA-4/VCAM-1 interaction in the absence of shear stress. Biophys J (2004) 0.97
Aspects of VLA-4 and LFA-1 regulation that may contribute to rolling and firm adhesion. Front Immunol (2012) 0.96
How natalizumab binds and antagonizes α4 integrins. J Biol Chem (2013) 0.95
Increased extracellular pressure enhances cancer cell integrin-binding affinity through phosphorylation of beta1-integrin at threonine 788/789. Am J Physiol Cell Physiol (2008) 0.91
Discovery of very late antigen-4 (VLA-4, alpha4beta1 integrin) allosteric antagonists. J Biol Chem (2010) 0.91
Genetic perturbation of the putative cytoplasmic membrane-proximal salt bridge aberrantly activates alpha(4) integrins. Blood (2008) 0.91
Adhesion between human neutrophils and immobilized endothelial ligand vascular cell adhesion molecule 1: divalent ion effects. Biophys J (2009) 0.85
Conformational mAb as a tool for integrin ligand discovery. Assay Drug Dev Technol (2009) 0.84
Nitric oxide/cGMP pathway signaling actively down-regulates α4β1-integrin affinity: an unexpected mechanism for inducing cell de-adhesion. BMC Immunol (2011) 0.82
UVB-irradiation regulates VLA-4-mediated melanoma cell adhesion to endothelial VCAM-1 under flow conditions. Mol Carcinog (2011) 0.82
Overview: assays for studying integrin-dependent cell adhesion. Methods Mol Biol (2012) 0.82
Real-time analysis of the inside-out regulation of lymphocyte function-associated antigen-1 revealed similarities to and differences from very late antigen-4. J Biol Chem (2011) 0.82
Bioactive hydrogel substrates: probing leukocyte receptor-ligand interactions in parallel plate flow chamber studies. Ann Biomed Eng (2006) 0.80
Therapeutic targeting and rapid mobilization of endosteal HSC using a small molecule integrin antagonist. Nat Commun (2016) 0.80
A dry membrane protection technique to allow surface acoustic wave biosensor measurements of biological model membrane approaches. Sensors (Basel) (2013) 0.75
Kindlin-3 Is Essential for the Resting α4β1 Integrin-mediated Firm Cell Adhesion under Shear Flow Conditions. J Biol Chem (2016) 0.75
A miniature Couette to generate shear for flow cytometry: studying real-time modulation of intracellular calcium in monocytic cells. Cytometry A (2011) 0.75
Carbon monoxide down-regulates α4β1 integrin-specific ligand binding and cell adhesion: a possible mechanism for cell mobilization. BMC Immunol (2014) 0.75
Does aberrant membrane transport contribute to poor outcome in adult acute myeloid leukemia? Front Pharmacol (2015) 0.75
A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science (2005) 9.80
Virtual and biomolecular screening converge on a selective agonist for GPR30. Nat Chem Biol (2006) 5.20
GPR30 expression is required for the mineralocorticoid receptor-independent rapid vascular effects of aldosterone. Hypertension (2011) 3.26
Estrogen signaling through the transmembrane G protein-coupled receptor GPR30. Annu Rev Physiol (2008) 3.20
G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells. Cancer Res (2007) 2.71
In vivo effects of a GPR30 antagonist. Nat Chem Biol (2009) 2.39
A crowdsourcing evaluation of the NIH chemical probes. Nat Chem Biol (2009) 2.29
Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system. J Endocrinol (2007) 2.20
Regulatory role of G protein-coupled estrogen receptor for vascular function and obesity. Circ Res (2009) 2.16
A flow cytometer for the measurement of Raman spectra. Cytometry A (2008) 2.16
Release of ubiquitin-charged Cdc34-S - Ub from the RING domain is essential for ubiquitination of the SCF(Cdc4)-bound substrate Sic1. Cell (2003) 1.94
Full characterization of GPCR monomer-dimer dynamic equilibrium by single molecule imaging. J Cell Biol (2011) 1.91
GPR30: a novel indicator of poor survival for endometrial carcinoma. Am J Obstet Gynecol (2007) 1.89
FRET detection of cellular alpha4-integrin conformational activation. Biophys J (2003) 1.88
Suspension array technology: evolution of the flat-array paradigm. Trends Biotechnol (2002) 1.81
Mechanical properties of primary cilia regulate the response to fluid flow. Am J Physiol Renal Physiol (2010) 1.72
Drug Repurposing from an Academic Perspective. Drug Discov Today Ther Strateg (2011) 1.68
GPR30 predicts poor survival for ovarian cancer. Gynecol Oncol (2009) 1.63
Discovery of regulators of receptor internalization with high-throughput flow cytometry. Mol Pharmacol (2012) 1.61
Chemotaxis inhibitory protein of Staphylococcus aureus binds specifically to the C5a and formylated peptide receptor. J Immunol (2004) 1.59
GPR30: A G protein-coupled receptor for estrogen. Mol Cell Endocrinol (2007) 1.59
Inactivation of the Cdkn2a locus cooperates with HMGA1 to drive T-cell leukemogenesis. Leuk Lymphoma (2013) 1.58
Particle focusing in staged inertial microfluidic devices for flow cytometry. Anal Chem (2010) 1.57
ATP hydrolysis-dependent disassembly of the 26S proteasome is part of the catalytic cycle. Cell (2005) 1.55
Arrestins block G protein-coupled receptor-mediated apoptosis. J Biol Chem (2004) 1.53
Flow cytometry for high-throughput, high-content screening. Curr Opin Chem Biol (2004) 1.50
Fluorescent genetic barcoding in mammalian cells for enhanced multiplexing capabilities in flow cytometry. Cytometry A (2013) 1.48
Analysis of low-abundance, low-molecular-weight serum proteins using mass spectrometry. J Biomol Tech (2004) 1.48
Regulation of cell adhesion by affinity and conformational unbending of alpha4beta1 integrin. J Immunol (2007) 1.43
Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity. J Steroid Biochem Mol Biol (2011) 1.42
Inactivation of LEF1 in T-cell acute lymphoblastic leukemia. Blood (2010) 1.40
Dysregulated FcepsilonRI signaling and altered Fyn and SHIP activities in Lyn-deficient mast cells. J Immunol (2004) 1.40
Synthetic estrogen derivatives demonstrate the functionality of intracellular GPR30. ACS Chem Biol (2007) 1.37
Integration of virtual screening with high-throughput flow cytometry to identify novel small molecule formylpeptide receptor antagonists. Mol Pharmacol (2005) 1.37
The G protein-coupled receptor GPR30 inhibits proliferation of estrogen receptor-positive breast cancer cells. Cancer Res (2010) 1.36
Metastatic melanoma imaging with an (111)In-labeled lactam bridge-cyclized alpha-melanocyte-stimulating hormone peptide. Nucl Med Biol (2009) 1.36
The ins and outs of GPR30: a transmembrane estrogen receptor. J Steroid Biochem Mol Biol (2008) 1.36
Associating Drugs, Targets and Clinical Outcomes into an Integrated Network Affords a New Platform for Computer-Aided Drug Repurposing. Mol Inform (2011) 1.35
Ultrasonic particle-concentration for sheathless focusing of particles for analysis in a flow cytometer. Cytometry A (2006) 1.35
Beneficial role of the GPR30 agonist G-1 in an animal model of multiple sclerosis. J Neuroimmunol (2009) 1.32
Open, reconfigurable cytometric acquisition system: ORCAS. Cytometry A (2007) 1.29
G protein-coupled receptors serve as mechanosensors for fluid shear stress in neutrophils. Am J Physiol Cell Physiol (2006) 1.29
G protein-coupled receptor 30 expression is required for estrogen stimulation of primordial follicle formation in the hamster ovary. Endocrinology (2008) 1.27
Membrane estrogen receptors stimulate intracellular calcium release and progesterone synthesis in hypothalamic astrocytes. J Neurosci (2010) 1.27
Localisation of GPR30, a novel G protein-coupled oestrogen receptor, suggests multiple functions in rodent brain and peripheral tissues. J Endocrinol (2009) 1.27
Analytical performance of an ultrasonic particle focusing flow cytometer. Anal Chem (2007) 1.26
GPR30: a novel therapeutic target in estrogen-related disease. Trends Pharmacol Sci (2008) 1.25
Vasodilation in response to the GPR30 agonist G-1 is not different from estradiol in the mRen2.Lewis female rat. J Cardiovasc Pharmacol (2011) 1.24
Characterization of a Cdc42 protein inhibitor and its use as a molecular probe. J Biol Chem (2013) 1.24
The G protein-coupled receptor GPR30 inhibits human urothelial cell proliferation. Endocrinology (2008) 1.23
N-formyl peptide receptors internalize but do not recycle in the absence of arrestins. J Biol Chem (2003) 1.23
Flow cytometric analysis of ligand-receptor interactions and molecular assemblies. Annu Rev Biophys Biomol Struct (2001) 1.23
High-throughput screening with HyperCyt flow cytometry to detect small molecule formylpeptide receptor ligands. J Biomol Screen (2005) 1.22
The development of quantum dot calibration beads and quantitative multicolor bioassays in flow cytometry and microscopy. Anal Biochem (2007) 1.22
Non-genomic regulation of vascular cell function and growth by estrogen. Mol Cell Endocrinol (2009) 1.21
High-throughput flow cytometry: validation in microvolume bioassays. Cytometry A (2003) 1.21
Single particle high resolution spectral analysis flow cytometry. Cytometry A (2006) 1.21
Estrogen and progesterone receptor status and outcome in epithelial ovarian cancers and low malignant potential tumors. Gynecol Oncol (2009) 1.21
Identification of genomic classifiers that distinguish induction failure in T-lineage acute lymphoblastic leukemia: a report from the Children's Oncology Group. Blood (2007) 1.19
Expression and intracellular distribution of the G protein-coupled receptor 30 in rat hippocampal formation. Neurosci Lett (2008) 1.19
Paroxetine is a direct inhibitor of g protein-coupled receptor kinase 2 and increases myocardial contractility. ACS Chem Biol (2012) 1.19
CD4(+) CD56(+) lineage-negative malignancies are rare tumors of plasmacytoid dendritic cells. Am J Surg Pathol (2005) 1.18
The G protein-coupled estrogen receptor GPER/GPR30 as a regulator of cardiovascular function. Vascul Pharmacol (2011) 1.18
Transcriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemia. Blood (2006) 1.17
Enhanced leukemia cell detection using a novel magnetic needle and nanoparticles. Cancer Res (2009) 1.17
Dilation of epicardial coronary arteries by the G protein-coupled estrogen receptor agonists G-1 and ICI 182,780. Pharmacology (2010) 1.17
Expression of G protein-coupled receptor-30, a G protein-coupled membrane estrogen receptor, in oxytocin neurons of the rat paraventricular and supraoptic nuclei. Endocrinology (2007) 1.17
Synthesis and characterization of iodinated tetrahydroquinolines targeting the G protein-coupled estrogen receptor GPR30. J Med Chem (2010) 1.16
Design and structure of peptide and peptidomimetic antagonists of protein-protein interaction. Curr Protein Pept Sci (2005) 1.16
Expression of G protein-coupled receptor 30 in the hamster ovary: differential regulation by gonadotropins and steroid hormones. Endocrinology (2007) 1.16
High-throughput flow cytometry to detect selective inhibitors of ABCB1, ABCC1, and ABCG2 transporters. Assay Drug Dev Technol (2008) 1.14
Abdominal wall and thigh abscess resulting from the penetration of ascending colon cancer. Acta Med Okayama (2005) 1.14
Characterization of magnetite nanoparticles for SQUID-relaxometry and magnetic needle biopsy. J Magn Magn Mater (2009) 1.14
Absence of biallelic TCRgamma deletion predicts early treatment failure in pediatric T-cell acute lymphoblastic leukemia. J Clin Oncol (2010) 1.14
Real-time analysis of conformation-sensitive antibody binding provides new insights into integrin conformational regulation. J Biol Chem (2009) 1.14
Retracted G-protein-coupled receptor 30 and estrogen receptor-alpha are involved in the proliferative effects induced by atrazine in ovarian cancer cells. Environ Health Perspect (2008) 1.13
Mechanisms of estradiol-induced insulin secretion by the G protein-coupled estrogen receptor GPR30/GPER in pancreatic beta-cells. Endocrinology (2011) 1.12
Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia. Blood (2009) 1.11