Published in Lancet Neurol on November 01, 2002
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Association of chronic obstructive pulmonary disease with cognitive decline in very elderly men. Dement Geriatr Cogn Dis Extra (2012) 0.91
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Mucosal tolerization to E-selectin protects against memory dysfunction and white matter damage in a vascular cognitive impairment model. J Cereb Blood Flow Metab (2007) 0.88
The potential for estrogens in preventing Alzheimer's disease and vascular dementia. Ther Adv Neurol Disord (2009) 0.87
Effectiveness and safety of citicoline in mild vascular cognitive impairment: the IDEALE study. Clin Interv Aging (2013) 0.87
Gliovascular disruption and cognitive deficits in a mouse model with features of small vessel disease. J Cereb Blood Flow Metab (2015) 0.87
The renin-angiotensin-aldosterone system in cerebral small vessel disease. J Neurol (2008) 0.87
White Matter Damage and Hippocampal Neurodegeneration Induced by Permanent Bilateral Occlusion of Common Carotid Artery in the Rat: Comparison between Wistar and Sprague-Dawley Strain. Korean J Physiol Pharmacol (2008) 0.86
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Identifying the neural correlates of executive functions in early cerebral microangiopathy: a combined VBM and DTI study. J Cereb Blood Flow Metab (2012) 0.86
Lessons from a mouse model characterizing features of vascular cognitive impairment with white matter changes. J Aging Res (2011) 0.86
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White matter hyperintensities and cognitive dysfunction in patients with infratentorial stroke. Ann Rehabil Med (2014) 0.85
Small vessel disease and subcortical vascular dementia. J Clin Neurol (2006) 0.85
Brain lipidomes of subcortical ischemic vascular dementia and mixed dementia. Neurobiol Aging (2014) 0.85
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Characteristics of MR infarcts associated with dementia and cognitive function in the elderly. Neuroepidemiology (2011) 0.84
Rapid and local autoregulation of cerebrovascular blood flow: a deep-brain imaging study in the mouse. J Physiol (2008) 0.84
Current status and future perspectives of magnetic resonance high-field imaging: a summary. Neuroimaging Clin N Am (2012) 0.83
Cardiotonic pill attenuates white matter and hippocampal damage via inhibiting microglial activation and downregulating ERK and p38 MAPK signaling in chronic cerebral hypoperfused rat. BMC Complement Altern Med (2013) 0.82
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Depressive symptoms as a predictor of quality of life in cerebral small vessel disease, acting independently of disability; a study in both sporadic small vessel disease and CADASIL. Int J Stroke (2012) 0.82
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Can the detection of misery perfusion in chronic cerebrovascular disease be based on reductions in baseline CBF and vasoreactivity? Eur J Nucl Med Mol Imaging (2006) 0.82
Microvascular pathology and morphometrics of sporadic and hereditary small vessel diseases of the brain. Brain Pathol (2014) 0.82
In vivo high-resolution 7 Tesla MRI shows early and diffuse cortical alterations in CADASIL. PLoS One (2014) 0.82
Rationale, design and methodology of the image analysis protocol for studies of patients with cerebral small vessel disease and mild stroke. Brain Behav (2015) 0.82
Chronic hypoperfusion alters the content and structure of proteins and lipids of rat brain homogenates: a Fourier transform infrared spectroscopy study. Eur Biophys J (2004) 0.81
The Gothenburg MCI study: Design and distribution of Alzheimer's disease and subcortical vascular disease diagnoses from baseline to 6-year follow-up. J Cereb Blood Flow Metab (2016) 0.81
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Neuroradiological findings in vascular dementia. Neuroradiology (2006) 0.80
Reproducibility and variability of quantitative magnetic resonance imaging markers in cerebral small vessel disease. J Cereb Blood Flow Metab (2016) 0.80
Hippocampal subfield volumetry in patients with subcortical vascular mild cognitive impairment. Sci Rep (2016) 0.79
Distribution of cerebral microbleeds determines their association with impaired kidney function. J Clin Neurol (2014) 0.79
Early treatment of minocycline alleviates white matter and cognitive impairments after chronic cerebral hypoperfusion. Sci Rep (2015) 0.79
Fructus mume alleviates chronic cerebral hypoperfusion-induced white matter and hippocampal damage via inhibition of inflammation and downregulation of TLR4 and p38 MAPK signaling. BMC Complement Altern Med (2015) 0.79
Comparison of medial temporal measures between Binswanger's disease and Alzheimer's disease. PLoS One (2014) 0.79
Effects of amyloid and vascular markers on cognitive decline in subcortical vascular dementia. Neurology (2015) 0.79
Gradual Carotid Artery Stenosis in Mice Closely Replicates Hypoperfusive Vascular Dementia in Humans. J Am Heart Assoc (2016) 0.79
Alterations of the cerebral cortex in sporadic small vessel disease: A systematic review of in vivo MRI data. J Cereb Blood Flow Metab (2016) 0.78
Delays in auditory-cued step initiation are related to increased volume of white matter hyperintensities in older adults. Exp Brain Res (2008) 0.78
Depression in small-vessel disease relates to white matter ultrastructural damage, not disability. Neurology (2014) 0.78
Impact of white matter lesions on cognition in stroke patients free from pre-stroke cognitive impairment: a one-year follow-up study. Dement Geriatr Cogn Dis Extra (2012) 0.78
The Combination of Dysexecutive and Amnestic Deficits Strongly Predicts Conversion to Dementia in Young Mild Cognitive Impairment Patients: A Report from the Gothenburg-Oslo MCI Study. Dement Geriatr Cogn Dis Extra (2014) 0.78
Neuroimaging in dementia. Semin Neurol (2008) 0.78
Cerebrovascular Biomarker Profile Is Related to White Matter Disease and Ventricular Dilation in a LADIS Substudy. Dement Geriatr Cogn Dis Extra (2014) 0.78
Disproportionate subarachnoid space hydrocephalus-outcome and perivascular space. Ann Clin Transl Neurol (2014) 0.78
Chronic Cerebral Ischemia Induces Downregulation of A1 Adenosine Receptors During White Matter Damage in Adult Mice. Cell Mol Neurobiol (2015) 0.77
Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association. Stroke (2011) 10.11
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07
The Uniform Data Set (UDS): clinical and cognitive variables and descriptive data from Alzheimer Disease Centers. Alzheimer Dis Assoc Disord (2006) 8.04
CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment. JAMA (2009) 7.29
National Institute of Neurological Disorders and Stroke-Canadian Stroke Network vascular cognitive impairment harmonization standards. Stroke (2006) 6.94
Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Lancet Neurol (2013) 6.18
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet (2010) 5.52
Simultaneous measurement of beta-amyloid(1-42), total tau, and phosphorylated tau (Thr181) in cerebrospinal fluid by the xMAP technology. Clin Chem (2004) 4.23
Vascular cognitive impairment. Lancet Neurol (2003) 3.73
Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases. Arch Neurol (2003) 3.57
Pattern of cerebral hypoperfusion in Alzheimer disease and mild cognitive impairment measured with arterial spin-labeling MR imaging: initial experience. Radiology (2005) 3.14
Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization. J Neurosci (2008) 2.77
Neuropathological basis of magnetic resonance images in aging and dementia. Ann Neurol (2008) 2.71
Small vessel disease and general cognitive function in nondisabled elderly: the LADIS study. Stroke (2005) 2.59
Progression of white matter hyperintensities and incidence of new lacunes over a 3-year period: the Leukoaraiosis and Disability study. Stroke (2008) 2.57
Evaluation of plasma Abeta(40) and Abeta(42) as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment. Neurobiol Aging (2008) 2.51
Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology (2012) 2.08
Do white matter hyperintensities on MRI matter clinically? BMJ (2010) 2.07
Correlates of hippocampal neuron number in Alzheimer's disease and ischemic vascular dementia. Ann Neurol (2005) 2.05
Impact of age-related cerebral white matter changes on the transition to disability -- the LADIS study: rationale, design and methodology. Neuroepidemiology (2005) 1.92
Longitudinal MRI and cognitive change in healthy elderly. Neuropsychology (2007) 1.88
Impact of white matter hyperintensities scoring method on correlations with clinical data: the LADIS study. Stroke (2006) 1.88
Confounding factors influencing amyloid Beta concentration in cerebrospinal fluid. Int J Alzheimers Dis (2010) 1.86
Age effects on atrophy rates of entorhinal cortex and hippocampus. Neurobiol Aging (2005) 1.83
On the etiology of incident brain lacunes: longitudinal observations from the LADIS study. Stroke (2008) 1.75
Profiles of neuropsychological impairment in autopsy-defined Alzheimer's disease and cerebrovascular disease. Brain (2007) 1.73
Prediction and longitudinal study of CSF biomarkers in mild cognitive impairment. Neurobiol Aging (2007) 1.61
Cerebrospinal fluid alpha-synuclein in neurodegenerative disorders-a marker of synapse loss? Neurosci Lett (2008) 1.60
Relationship between progression of brain white matter changes and late-life depression: 3-year results from the LADIS study. Br J Psychiatry (2012) 1.57
Increased intrathecal levels of the angiogenic factors VEGF and TGF-beta in Alzheimer's disease and vascular dementia. Neurobiol Aging (2002) 1.56
Diffusion changes predict cognitive and functional outcome: the LADIS study. Ann Neurol (2013) 1.54
Intra-individual stability of CSF biomarkers for Alzheimer's disease over two years. J Alzheimers Dis (2007) 1.54
A randomized controlled comparison of upper-extremity rehabilitation strategies in acute stroke: A pilot study of immediate and long-term outcomes. Arch Phys Med Rehabil (2004) 1.53
Risk of rapid global functional decline in elderly patients with severe cerebral age-related white matter changes: the LADIS study. Arch Intern Med (2007) 1.52
Further molecular and clinical delineation of co-locating 17p13.3 microdeletions and microduplications that show distinctive phenotypes. J Med Genet (2010) 1.50
Neurochemical aftermath of amateur boxing. Arch Neurol (2006) 1.47
Heterogeneity in age-related white matter changes. Acta Neuropathol (2011) 1.47
Understanding hippocampal sclerosis in the elderly: epidemiology, characterization, and diagnostic issues. Curr Neurol Neurosci Rep (2008) 1.47
Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Hum Mol Genet (2012) 1.46
2001-2011: A Decade of the LADIS (Leukoaraiosis And DISability) Study: What Have We Learned about White Matter Changes and Small-Vessel Disease? Cerebrovasc Dis (2011) 1.40
Levels of beta-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment. Arch Gen Psychiatry (2007) 1.38
Vascular cognitive disorder: a new diagnostic category updating vascular cognitive impairment and vascular dementia. J Neurol Sci (2004) 1.38
Cerebrovascular disease, β-amyloid, and cognition in aging. Neurobiol Aging (2011) 1.37
White matter lesions are associated with cortical atrophy more than entorhinal and hippocampal atrophy. Neurobiol Aging (2005) 1.36
Neuron loss in key cholinergic and aminergic nuclei in Alzheimer disease: a meta-analysis. Neurobiol Aging (2002) 1.35
Memory in the aging brain: doubly dissociating the contribution of the hippocampus and entorhinal cortex. Hippocampus (2007) 1.32
Subcortical lacunes are associated with executive dysfunction in cognitively normal elderly. Stroke (2007) 1.27
Magnetic resonance imaging improves cerebrospinal fluid biomarkers in the early detection of Alzheimer's disease. J Alzheimers Dis (2009) 1.26
White matter hyperintensities rather than lacunar infarcts are associated with depressive symptoms in older people: the LADIS study. Am J Geriatr Psychiatry (2006) 1.26
Longitudinal cognitive decline in subcortical ischemic vascular disease--the LADIS Study. Cerebrovasc Dis (2009) 1.25
The aging brain and cognition: contribution of vascular injury and aβ to mild cognitive dysfunction. JAMA Neurol (2013) 1.25
Age, hypertension, and lacunar stroke are the major determinants of the severity of age-related white matter changes. The LADIS (Leukoaraiosis and Disability in the Elderly) Study. Cerebrovasc Dis (2006) 1.20
Increased CSF-BACE 1 activity is associated with ApoE-epsilon 4 genotype in subjects with mild cognitive impairment and Alzheimer's disease. Brain (2008) 1.20
Operationalizing diagnostic criteria for Alzheimer's disease and other age-related cognitive impairment-Part 2. Alzheimers Dement (2011) 1.19
Coronary risk correlates with cerebral amyloid deposition. Neurobiol Aging (2011) 1.17
Differential impact of cerebral white matter changes, diabetes, hypertension and stroke on cognitive performance among non-disabled elderly. The LADIS study. J Neurol Neurosurg Psychiatry (2007) 1.17
Two-year outcome of MCI subtypes and aetiologies in the Göteborg MCI study. J Neurol Neurosurg Psychiatry (2009) 1.15
Cerebrospinal fluid matrix metalloproteinases and tissue inhibitor of metalloproteinases in combination with subcortical and cortical biomarkers in vascular dementia and Alzheimer's disease. J Alzheimers Dis (2011) 1.14
Physical activity prevents progression for cognitive impairment and vascular dementia: results from the LADIS (Leukoaraiosis and Disability) study. Stroke (2012) 1.13
Blood pressure components and changes in relation to white matter lesions: a 32-year prospective population study. Hypertension (2009) 1.12
Corpus callosum atrophy is associated with mental slowing and executive deficits in subjects with age-related white matter hyperintensities: the LADIS Study. J Neurol Neurosurg Psychiatry (2006) 1.12
An Alzheimer's disease-specific beta-amyloid fragment signature in cerebrospinal fluid. Neurosci Lett (2006) 1.11
Cognitive impairment and chronic cerebral hypoperfusion: what can be learned from experimental models. J Neurol Sci (2002) 1.10
Validation of a posturographic approach to monitor sleepiness. J Biomech (2010) 1.10
Cerebral pattern of pro- and anti-inflammatory cytokines in dementias. Brain Res Bull (2003) 1.10
Hippocampal volume and retention in Alzheimer's disease. J Int Neuropsychol Soc (2004) 1.09
Cerebral hemorrhages in CADASIL: report of four cases and a brief review. J Neurol Sci (2013) 1.08
The effect of white matter lesions on cognition in the elderly--small but detectable. Nat Clin Pract Neurol (2007) 1.07
Cross-national comparison and validation of the Alzheimer's Disease Assessment Scale: results from the European Harmonization Project for Instruments in Dementia (EURO-HARPID). Int J Geriatr Psychiatry (2004) 1.07
Reduced levels of amyloid-beta-binding proteins in cerebrospinal fluid from Alzheimer's disease patients. J Alzheimers Dis (2009) 1.07