Published in Cell Cycle on July 09, 2003
Acetylated lysine 56 on histone H3 drives chromatin assembly after repair and signals for the completion of repair. Cell (2008) 4.14
Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance. EMBO J (2004) 1.94
Taking the time to make important decisions: the checkpoint effector kinases Chk1 and Chk2 and the DNA damage response. DNA Repair (Amst) (2009) 1.89
Histone deposition protein Asf1 maintains DNA replisome integrity and interacts with replication factor C. Genes Dev (2005) 1.62
The histone chaperone Asf1 at the crossroads of chromatin and DNA checkpoint pathways. Chromosoma (2006) 1.48
Rad53 phosphorylation site clusters are important for Rad53 regulation and signaling. Mol Cell Biol (2003) 1.42
An FHA domain-mediated protein interaction network of Rad53 reveals its role in polarized cell growth. J Cell Biol (2006) 1.40
Genetic interaction of RAD53 protein kinase with histones is important for DNA replication. Cell Cycle (2010) 1.40
Pph3-Psy2 is a phosphatase complex required for Rad53 dephosphorylation and replication fork restart during recovery from DNA damage. Proc Natl Acad Sci U S A (2007) 1.32
DNA-repair scaffolds dampen checkpoint signalling by counteracting the adaptor Rad9. Nature (2012) 1.22
Critical role of DNA checkpoints in mediating genotoxic-stress-induced filamentous growth in Candida albicans. Mol Biol Cell (2006) 1.20
RecQ helicases: lessons from model organisms. Nucleic Acids Res (2006) 1.19
Mechanisms of checkpoint kinase Rad53 inactivation after a double-strand break in Saccharomyces cerevisiae. Mol Cell Biol (2007) 1.12
Mdt1, a novel Rad53 FHA1 domain-interacting protein, modulates DNA damage tolerance and G(2)/M cell cycle progression in Saccharomyces cerevisiae. Mol Cell Biol (2004) 1.08
CDC5 inhibits the hyperphosphorylation of the checkpoint kinase Rad53, leading to checkpoint adaptation. PLoS Biol (2010) 1.05
Regulation of histone deposition proteins Asf1/Hir1 by multiple DNA damage checkpoint kinases in Saccharomyces cerevisiae. Genetics (2005) 1.04
A Ddc2-Rad53 fusion protein can bypass the requirements for RAD9 and MRC1 in Rad53 activation. Mol Biol Cell (2004) 0.95
Chromatin disassembly and reassembly during DNA repair. Mutat Res (2007) 0.95
Replication checkpoint: tuning and coordination of replication forks in s phase. Genes (Basel) (2013) 0.95
Novel role for checkpoint Rad53 protein kinase in the initiation of chromosomal DNA replication in Saccharomyces cerevisiae. Genetics (2006) 0.91
Surprising complexity of the Asf1 histone chaperone-Rad53 kinase interaction. Proc Natl Acad Sci U S A (2012) 0.84
A strategy for interaction site prediction between phospho-binding modules and their partners identified from proteomic data. Mol Cell Proteomics (2010) 0.83
Genome-wide identification and comprehensive analyses of the kinomes in four pathogenic microsporidia species. PLoS One (2014) 0.82
The C terminus of the histone chaperone Asf1 cross-links to histone H3 in yeast and promotes interaction with histones H3 and H4. Mol Cell Biol (2012) 0.80
Pph3 dephosphorylation of Rad53 is required for cell recovery from MMS-induced DNA damage in Candida albicans. PLoS One (2012) 0.78
Use of quantitative mass spectrometric analysis to elucidate the mechanisms of phospho-priming and auto-activation of the checkpoint kinase Rad53 in vivo. Mol Cell Proteomics (2013) 0.76
Global analysis of protein phosphorylation in yeast. Nature (2005) 7.46
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat Genet (2012) 7.00
Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs. Sci Signal (2010) 2.95
Relationship of epidermal growth factor receptor expression to ErbB-2 signaling activity and prognosis in breast cancer patients. J Clin Oncol (2005) 2.95
Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β. J Clin Invest (2010) 2.64
Neural and mammary gland defects in ErbB4 knockout mice genetically rescued from embryonic lethality. Proc Natl Acad Sci U S A (2003) 2.38
Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint. Mol Cell (2002) 2.30
Barcoding bias in high-throughput multiplex sequencing of miRNA. Genome Res (2011) 2.12
Genotype-selective combination therapies for melanoma identified by high-throughput drug screening. Cancer Discov (2012) 1.97
Levator excursion as a predictor of both eyelid lag and lagophthalmos in thyroid eye disease. Ophthal Plast Reconstr Surg (2010) 1.95
Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCA1. J Biol Chem (2004) 1.89
Chk2 activation and phosphorylation-dependent oligomerization. Mol Cell Biol (2002) 1.88
Optimal injection volume of epinephrine for endoscopic prevention of recurrent peptic ulcer bleeding. Gastrointest Endosc (2004) 1.58
SHP-2 positively regulates myogenesis by coupling to the Rho GTPase signaling pathway. Mol Cell Biol (2004) 1.53
Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody. J Biol Chem (2002) 1.44
Quinone oxidoreductase (NQO1) gene polymorphism (609C/T) may be associated with tardive dyskinesia, but not with the development of schizophrenia. Int J Neuropsychopharmacol (2004) 1.43
Rad53 phosphorylation site clusters are important for Rad53 regulation and signaling. Mol Cell Biol (2003) 1.42
Phosphoproteomic screen identifies potential therapeutic targets in melanoma. Mol Cancer Res (2011) 1.38
Decreased plasma antioxidants in patients with Alzheimer's disease. Int J Geriatr Psychiatry (2006) 1.37
NFBD1/KIAA0170 is a chromatin-associated protein involved in DNA damage signaling pathways. J Biol Chem (2002) 1.37
NFBD1/MDC1 regulates ionizing radiation-induced focus formation by DNA checkpoint signaling and repair factors. FASEB J (2003) 1.37
Regulation of CHK2 by DNA-dependent protein kinase. J Biol Chem (2005) 1.29
ErbB2 is required for ductal morphogenesis of the mammary gland. Proc Natl Acad Sci U S A (2004) 1.29
Interaction of chromatin-associated Plk1 and Mcm7. J Biol Chem (2005) 1.21
Phosphorylated/activated HER2 as a marker of clinical resistance to single agent taxane chemotherapy for metastatic breast cancer. Cancer Invest (2005) 1.14
DNA damage regulates Chk2 association with chromatin. J Biol Chem (2005) 1.11
Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage. Cell Cycle (2005) 1.10
ErbB3 is required for ductal morphogenesis in the mouse mammary gland. Breast Cancer Res (2008) 1.06
Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy. Proc Natl Acad Sci U S A (2010) 1.03
Activation of the checkpoint kinase Rad53 by the phosphatidyl inositol kinase-like kinase Mec1. J Biol Chem (2005) 1.03
EGF receptor activates MET through MAPK to enhance non-small cell lung carcinoma invasion and brain metastasis. Cancer Res (2013) 0.99
Comparative outcome analysis of ABO-incompatible and positive crossmatch renal transplantation: a single-center experience. Transplantation (2009) 0.99
NFBD1/MDC1, 53BP1 and BRCA1 have both redundant and unique roles in the ATM pathway. Cell Cycle (2008) 0.99
BanI polymorphism of the cytosolic phospholipase A2 gene and mood disorders in the Korean population. Neuropsychobiology (2004) 0.98
Safety and tolerability of lamotrigine: results from 12 placebo-controlled clinical trials and clinical implications. Clin Neuropharmacol (2011) 0.97
Centrosomal Chk2 in DNA damage responses and cell cycle progression. Cell Cycle (2010) 0.95
A Ddc2-Rad53 fusion protein can bypass the requirements for RAD9 and MRC1 in Rad53 activation. Mol Biol Cell (2004) 0.95
A pilot trial of quetiapine for the treatment of patients with delirium. Hum Psychopharmacol (2004) 0.95
Oxidative/nitrosative stress and antidepressants: targets for novel antidepressants. Prog Neuropsychopharmacol Biol Psychiatry (2012) 0.94
Active signaling by HER-2/neu in a subpopulation of HER-2/neu-overexpressing ductal carcinoma in situ: clinicopathological correlates. Cancer Res (2002) 0.94
Influence of BDNF variants on diagnosis and response to treatment in patients with major depression, bipolar disorder and schizophrenia. Neuropsychobiology (2011) 0.93
Halting progressive neurodegeneration in advanced retinitis pigmentosa. J Clin Invest (2015) 0.93
Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain. Nucleic Acids Res (2012) 0.93
Blueberry peel extracts inhibit adipogenesis in 3T3-L1 cells and reduce high-fat diet-induced obesity. PLoS One (2013) 0.92
Polymorphisms of heat shock protein 70 gene (HSPA1A, HSPA1B and HSPA1L) and schizophrenia. Neurosci Res (2005) 0.92
High-throughput multiplex sequencing of miRNA. Curr Protoc Hum Genet (2012) 0.91
Effects of maternal breathing rate, psychiatric status, and cortisol on fetal heart rate. Dev Psychobiol (2010) 0.91
Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to treatment in patients with major depressive disorder. Eur Arch Psychiatry Clin Neurosci (2011) 0.91
Carbazole is a naturally occurring inhibitor of angiogenesis and inflammation isolated from antipsoriatic coal tar. J Invest Dermatol (2006) 0.88
Working memory processing of facial images in schizophrenia: fMRI investigation. Int J Neurosci (2005) 0.88
5'RNA-Seq identifies Fhl1 as a genetic modifier in cardiomyopathy. J Clin Invest (2014) 0.88
Schisandra chinensis prevents alcohol-induced fatty liver disease in rats. J Med Food (2014) 0.87
Association of the trace amine associated receptor 6 (TAAR6) gene with schizophrenia and bipolar disorder in a Korean case control sample. J Psychiatr Res (2006) 0.87
Case-control association study for 10 genes in patients with schizophrenia: influence of 5HTR1A variation rs10042486 on schizophrenia and response to antipsychotics. Eur Arch Psychiatry Clin Neurosci (2011) 0.87
Glutathione S-transferase M1 polymorphism may contribute to schizophrenia in the Korean population. Psychiatr Genet (2004) 0.86
The Plk1 Polo box domain mediates a cell cycle and DNA damage regulated interaction with Chk2. Cell Cycle (2005) 0.86
Second-generation antipsychotics in the treatment of major depressive disorder: current evidence. Expert Rev Neurother (2013) 0.85
Effect of 5-haplotype of dysbindin gene (DTNBP1) polymorphisms for the susceptibility to bipolar I disorder. Am J Med Genet B Neuropsychiatr Genet (2007) 0.85
A review of current evidence for vilazodone in major depressive disorder. Int J Psychiatry Clin Pract (2013) 0.85
NFBD1/MDC1 regulates Cav1 and Cav2 independently of DNA damage and p53. Mol Cancer Res (2011) 0.85
Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways. Mol Cancer Res (2010) 0.84
MERTK controls melanoma cell migration and survival and differentially regulates cell behavior relative to AXL. Pigment Cell Melanoma Res (2013) 0.84
Monocyte chemoattractant protein-1 (MCP1) promoter -2518 polymorphism may confer a susceptibility to major depressive disorder in the Korean population. Psychiatry Res (2004) 0.83
Gene expression profiling of ErbB receptor and ligand-dependent transcription. Oncogene (2004) 0.83
Comparison of HER2 and phospho-HER2 expression between biopsy and resected breast cancer specimens using a quantitative assessment method. PLoS One (2013) 0.83
Interrelationships among pain, disability, and psychological factors in young Korean conscripts with lumbar disc herniation. Mil Med (2006) 0.83
Paliperidone-associated atypical neuroleptic malignant syndrome: a case report. Prog Neuropsychopharmacol Biol Psychiatry (2010) 0.83
Association study between glutathione S-transferase P1 polymorphism and schizophrenia in the Korean population. Prog Neuropsychopharmacol Biol Psychiatry (2003) 0.83
Case-control association study of 36 single-nucleotide polymorphisms within 10 candidate genes for major depression and bipolar disorder. Psychiatry Res (2012) 0.82
Regulation of the Rad53 protein kinase in signal amplification by oligomer assembly and disassembly. Cell Cycle (2008) 0.81
Very low dose quetiapine-induced galactorrhea in combination with venlafaxine. Hum Psychopharmacol (2004) 0.81
Age-related autocrine diabetogenic effects of transgenic resistin in spontaneously hypertensive rats: gene expression profile analysis. Physiol Genomics (2011) 0.81
Case-control association study of 14 variants of CREB1, CREBBP and CREM on diagnosis and treatment outcome in major depressive disorder and bipolar disorder. Psychiatry Res (2012) 0.81
Neuregulin-regulated gene expression in mammary carcinoma cells. Exp Cell Res (2005) 0.81
Direct resequencing of the complete ERBB2 coding sequence reveals an absence of activating mutations in ERBB2 amplified breast cancer. Genes Chromosomes Cancer (2008) 0.81
Paroxetine-associated spontaneous sexual stimulation. Int Clin Psychopharmacol (2005) 0.81
BanI polymorphism of the cytosolic phospholipase A2 gene may confer susceptibility to the development of schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry (2004) 0.80
Effect of nizatidine on olanzapine-associated weight gain in schizophrenic patients in Korea: a pilot study. Hum Psychopharmacol (2003) 0.80
Clinical significance of autoantibody expression in allogeneic stem-cell recipients. Transplantation (2009) 0.80
Antipsychotic treatment may alter T-helper (TH) 2 arm cytokines. Int Immunopharmacol (2005) 0.80
Naturalistic observation on the hepatic enzyme changes in patients treated with either risperidone or olanzapine alone. Int Clin Psychopharmacol (2005) 0.80
Dysbindin associated with selective serotonin reuptake inhibitor antidepressant efficacy. Pharmacogenet Genomics (2007) 0.80
Heat-shock protein-70 genes and response to antidepressants in major depression. Prog Neuropsychopharmacol Biol Psychiatry (2007) 0.80
Polymorphism of the serotonin transporter gene and symptomatic dimensions of schizophrenia in the Korean population. Neuropsychobiology (2003) 0.80
Rapid titration versus conventional titration of quetiapine in the treatment of bipolar mania: a preliminary trial. Int Clin Psychopharmacol (2005) 0.79
Influence of activation state of ErbB-2 (HER-2) on response to adjuvant cyclophosphamide, doxorubicin, and fluorouracil for stage II, node-positive breast cancer: study 8541 from the Cancer and Leukemia Group B. J Clin Oncol (2008) 0.79
Neuronal dysfunction of the frontal lobe in schizophrenia. Neuropsychobiology (2004) 0.79
Aberration of cholesterol level in first-onset bipolar I patients. J Affect Disord (2004) 0.79
Manganese superoxide dismutase (MnSOD: Ala-9Val) gene polymorphism may not be associated with schizophrenia and tardive dyskinesia. Psychiatry Res (2007) 0.79
Monocyte chemoattractant protein-1 promoter -2518 polymorphism may have an influence on clinical heterogeneity of bipolar I disorder in the Korean population. Neuropsychobiology (2004) 0.79
Investigation of epistasis between DAOA and 5HTR1A variants on clinical outcomes in patients with schizophrenia. Genet Test Mol Biomarkers (2013) 0.79
Asenapine, blonanserin, iloperidone, lurasidone, and sertindole: distinctive clinical characteristics of 5 novel atypical antipsychotics. Clin Neuropharmacol (2013) 0.79
Atypical antipsychotics as a possible treatment option for irritable bowel syndrome. Expert Opin Investig Drugs (2013) 0.79
Reprogramming metabolism by targeting sirtuin 6 attenuates retinal degeneration. J Clin Invest (2016) 0.78