Hon Cheung Lee

Author PubWeight™ 30.93‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 NAADP: a universal Ca2+ trigger. Sci Signal 2008 1.96
2 A novel cycling assay for cellular cADP-ribose with nanomolar sensitivity. Biochem J 2002 1.55
3 Crystal structure of human CD38 extracellular domain. Structure 2005 1.29
4 Acidic residues at the active sites of CD38 and ADP-ribosyl cyclase determine nicotinic acid adenine dinucleotide phosphate (NAADP) synthesis and hydrolysis activities. J Biol Chem 2006 1.13
5 Cyclic ADP-ribose is a second messenger in the lipopolysaccharide-stimulated proliferation of human peripheral blood mononuclear cells. Biochem J 2003 1.06
6 The membrane-bound enzyme CD38 exists in two opposing orientations. Sci Signal 2012 1.04
7 Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis. J Biol Chem 2006 1.03
8 Ca(2+) signaling occurs via second messenger release from intraorganelle synthesis sites. Curr Biol 2008 1.00
9 Covalent and noncovalent intermediates of an NAD utilizing enzyme, human CD38. Chem Biol 2008 0.98
10 Evidence for a causal role of CD38 expression in granulocytic differentiation of human HL-60 cells. J Biol Chem 2002 0.96
11 Regulation of nuclear Ca2+ signaling by translocation of the Ca2+ messenger synthesizing enzyme ADP-ribosyl cyclase during neuronal depolarization. J Biol Chem 2008 0.95
12 A novel cycling assay for nicotinic acid-adenine dinucleotide phosphate with nanomolar sensitivity. Biochem J 2002 0.95
13 Catalysis-associated conformational changes revealed by human CD38 complexed with a non-hydrolyzable substrate analog. J Biol Chem 2007 0.95
14 Mechanism of cyclizing NAD to cyclic ADP-ribose by ADP-ribosyl cyclase and CD38. J Biol Chem 2009 0.93
15 Autocrine/paracrine function of nicotinic acid adenine dinucleotide phosphate (NAADP) for glucose homeostasis in pancreatic β-cells and adipocytes. J Biol Chem 2013 0.92
16 Structural basis for enzymatic evolution from a dedicated ADP-ribosyl cyclase to a multifunctional NAD hydrolase. J Biol Chem 2009 0.91
17 Mechanism-based small molecule probes for labeling CD38 on live cells. J Am Chem Soc 2009 0.90
18 Structural basis for formation and hydrolysis of the calcium messenger cyclic ADP-ribose by human CD38. J Biol Chem 2006 0.87
19 Nuclear CD38 in retinoic acid-induced HL-60 cells. Exp Cell Res 2005 0.86
20 ADP-ribosyl cyclase; crystal structures reveal a covalent intermediate. Structure 2004 0.86
21 CD38 Structure-Based Inhibitor Design Using the N1-Cyclic Inosine 5'-Diphosphate Ribose Template. PLoS One 2013 0.84
22 Design, synthesis and biological characterization of novel inhibitors of CD38. Org Biomol Chem 2011 0.83
23 Cytosolic CD38 protein forms intact disulfides and is active in elevating intracellular cyclic ADP-ribose. J Biol Chem 2011 0.83
24 Emerging role of cyclic ADP-ribose (cADPR) in smooth muscle. Pharmacol Ther 2004 0.82
25 Roles of cADPR and NAADP in pancreatic cells. Acta Biochim Biophys Sin (Shanghai) 2012 0.81
26 Structural studies of intermediates along the cyclization pathway of Aplysia ADP-ribosyl cyclase. J Mol Biol 2011 0.80
27 High throughput fluorescence-based assays for cyclic ADP-ribose, NAADP, and their metabolic enzymes. Comb Chem High Throughput Screen 2003 0.79
28 Cyclic ADP-ribose links metabolism to multiple fission in the dinoflagellate Crypthecodinium cohnii. Cell Calcium 2009 0.79
29 Hierarchical and helical self-assembly of ADP-ribosyl cyclase into large-scale protein microtubes. J Phys Chem B 2008 0.78
30 Conformational Closure of the Catalytic Site of Human CD38 Induced by Calcium (dagger) (double dagger). Biochemistry 2008 0.77
31 Determination of ADP-ribosyl cyclase activity, cyclic ADP-ribose, and nicotinic acid adenine dinucleotide phosphate in tissue extracts. Methods Mol Biol 2013 0.77
32 Identification of ADP-ribosylation sites of CD38 mutants by precursor ion scanning mass spectrometry. Anal Biochem 2012 0.76
33 Catalysis-based inhibitors of the calcium signaling function of CD38. Biochemistry 2011 0.76
34 Conformational Closure of the Catalytic Site of Human CD38 Induced by Calcium. Biochemistry 2008 0.75