Published in J Am Chem Soc on February 11, 2009
Protein arginine deiminase 4: a target for an epigenetic cancer therapy. Cell Mol Life Sci (2010) 1.21
Clickable NAD analogues for labeling substrate proteins of poly(ADP-ribose) polymerases. J Am Chem Soc (2010) 1.18
ATRA-induced HL-60 myeloid leukemia cell differentiation depends on the CD38 cytosolic tail needed for membrane localization, but CD38 enzymatic activity is unnecessary. Exp Cell Res (2010) 0.87
Revealing CD38 cellular localization using a cell permeable, mechanism-based fluorescent small-molecule probe. J Am Chem Soc (2014) 0.80
Identification of ADP-ribosylation sites of CD38 mutants by precursor ion scanning mass spectrometry. Anal Biochem (2012) 0.76
Synthesis and Evaluation of Thiazoloquinolinones with Linkers To Enable Targeting of CD38. ACS Med Chem Lett (2016) 0.75
CD38 in the pathogenesis of allergic airway disease: Potential therapeutic targets. Pharmacol Ther (2016) 0.75
A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes. Angew Chem Int Ed Engl (2002) 24.12
Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides. J Org Chem (2002) 13.76
Site-specific labeling of cell surface proteins with biophysical probes using biotin ligase. Nat Methods (2005) 5.21
Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology. Physiol Rev (2008) 2.92
Formation and hydrolysis of cyclic ADP-ribose catalyzed by lymphocyte antigen CD38. Science (1993) 2.85
Physiological functions of cyclic ADP-ribose and NAADP as calcium messengers. Annu Rev Pharmacol Toxicol (2001) 2.83
CD38 is critical for social behaviour by regulating oxytocin secretion. Nature (2007) 2.44
CD38 and CD100 lead a network of surface receptors relaying positive signals for B-CLL growth and survival. Blood (2004) 1.63
Human CD38 (ADP-ribosyl cyclase) is a counter-receptor of CD31, an Ig superfamily member. J Immunol (1998) 1.59
Interaction between endothelium and CD4+CD45RA+ lymphocytes. Role of the human CD38 molecule. J Immunol (1994) 1.44
The CD38 lymphocyte differentiation marker: new insight into its ectoenzymatic activity and its role as a signal transducer. Immunity (1997) 1.35
CD38 disruption impairs glucose-induced increases in cyclic ADP-ribose, [Ca2+]i, and insulin secretion. J Biol Chem (1999) 1.31
Signaling properties of CD38 in the mouse immune system: enzyme-dependent and -independent roles in immunity. Mol Med (2007) 1.24
NAD glycohydrolase specifically induced by retinoic acid in human leukemic HL-60 cells. Identification of the NAD glycohydrolase as leukocyte cell surface antigen CD38. J Biol Chem (1993) 1.11
CD38/CD19: a lipid raft-dependent signaling complex in human B cells. Blood (2007) 1.11
Secretion of IFN-gamma, IL-6, granulocyte-macrophage colony-stimulating factor and IL-10 cytokines after activation of human purified T lymphocytes upon CD38 ligation. Cell Immunol (1996) 1.05
CD38 signaling in T cells is initiated within a subset of membrane rafts containing Lck and the CD3-zeta subunit of the T cell antigen receptor. J Biol Chem (2003) 1.05
CD38 is associated with lipid rafts and upon receptor stimulation leads to Akt/protein kinase B and Erk activation in the absence of the CD3-zeta immune receptor tyrosine-based activation motifs. J Biol Chem (2001) 1.03
Retinoic acid-induced CD38 expression in HL-60 myeloblastic leukemia cells regulates cell differentiation or viability depending on expression levels. J Cell Biochem (2006) 1.02
Suppressed insulin signaling and increased apoptosis in CD38-null islets. Diabetes (2006) 1.02
CD38 as a prognostic marker in CLL. Hematology (2005) 0.99
Single-cell FRET imaging of transferrin receptor trafficking dynamics by Sfp-catalyzed, site-specific protein labeling. Chem Biol (2005) 0.99
Tyrosine phosphorylation of the c-cbl proto-oncogene product mediated by cell surface antigen CD38 in HL-60 cells. J Biol Chem (1996) 0.96
Antigen-induced clustering of surface CD38 and recruitment of intracellular CD38 to the immunologic synapse. Blood (2008) 0.95
CD38 ligation results in activation of the Raf-1/mitogen-activated protein kinase and the CD3-zeta/zeta-associated protein-70 signaling pathways in Jurkat T lymphocytes. J Immunol (1997) 0.93
Mechanism-based inhibitors of CD38: a mammalian cyclic ADP-ribose synthetase. Biochemistry (2002) 0.89
Antidiabetic effect of a prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid, through CD38 dimerization and internalization. J Biol Chem (2001) 0.85
Functional topography of discrete domains of human CD38. Tissue Antigens (2000) 0.84
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase. Science (2011) 4.16
The low-density lipoprotein receptor plays a role in the infection of primary human hepatocytes by hepatitis C virus. J Hepatol (2006) 2.74
The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2. Proc Natl Acad Sci U S A (2006) 2.63
SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine. Nature (2013) 2.52
How pathogenic bacteria evade mammalian sabotage in the battle for iron. Nat Chem Biol (2006) 2.45
Crystal structure of mammalian cysteine dioxygenase. A novel mononuclear iron center for cysteine thiol oxidation. J Biol Chem (2006) 2.30
Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP. Nat Struct Mol Biol (2013) 2.14
Improved expression of halorhodopsin for light-induced silencing of neuronal activity. Brain Cell Biol (2008) 2.12
Structure of human MRG15 chromo domain and its binding to Lys36-methylated histone H3. Nucleic Acids Res (2006) 2.09
Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans. Nature (2005) 2.08
c-kit expression identifies cardiovascular precursors in the neonatal heart. Proc Natl Acad Sci U S A (2009) 2.06
CD38 is a signaling molecule in B-cell chronic lymphocytic leukemia cells. Blood (2003) 1.99
NAADP: a universal Ca2+ trigger. Sci Signal (2008) 1.96
The structural basis for activation of plant immunity by bacterial effector protein AvrPto. Nature (2007) 1.95
Diphthamide biosynthesis requires an organic radical generated by an iron-sulphur enzyme. Nature (2010) 1.85
Crystal structure of the Caenorhabditis elegans apoptosome reveals an octameric assembly of CED-4. Cell (2010) 1.73
Structural basis for modulation of Kv4 K+ channels by auxiliary KChIP subunits. Nat Neurosci (2006) 1.70
Crystal structure of NDM-1 reveals a common β-lactam hydrolysis mechanism. FASEB J (2011) 1.63
CD38 and CD100 lead a network of surface receptors relaying positive signals for B-CLL growth and survival. Blood (2004) 1.63
Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter. Nature (2012) 1.56
A novel cycling assay for cellular cADP-ribose with nanomolar sensitivity. Biochem J (2002) 1.55
TfR2 localizes in lipid raft domains and is released in exosomes to activate signal transduction along the MAPK pathway. J Cell Sci (2006) 1.55
In vitro characterization of IroB, a pathogen-associated C-glycosyltransferase. Proc Natl Acad Sci U S A (2004) 1.52
Efficient three-component one-pot synthesis of fully substituted pyridin-2(1H)-ones via tandem Knoevenagel condensation-ring-opening of cyclopropane-intramolecular cyclization. Chem Commun (Camb) (2009) 1.52
Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD. Biochemistry (2009) 1.51
Angiographically evident atherosclerotic stenosis associated with myocardial bridging and risk factors for the artery stenosis located proximally to myocardial bridging. Anadolu Kardiyol Derg (2013) 1.38
Programming peptidomimetic syntheses by translating genetic codes designed de novo. Proc Natl Acad Sci U S A (2003) 1.38
Involvement of microRNA-93, a new regulator of PTEN/Akt signaling pathway, in regulation of chemotherapeutic drug cisplatin chemosensitivity in ovarian cancer cells. FEBS Lett (2012) 1.35
CD38 and ZAP-70 are functionally linked and mark CLL cells with high migratory potential. Blood (2007) 1.35
Two genetic variants of CD38 in subjects with autism spectrum disorder and controls. Neurosci Res (2010) 1.35
CD38/CD31, the CCL3 and CCL4 chemokines, and CD49d/vascular cell adhesion molecule-1 are interchained by sequential events sustaining chronic lymphocytic leukemia cell survival. Cancer Res (2009) 1.34
Plasmodium falciparum Sir2A preferentially hydrolyzes medium and long chain fatty acyl lysine. ACS Chem Biol (2011) 1.33
Crystal structure of human CD38 extracellular domain. Structure (2005) 1.29
CD molecules 2005: human cell differentiation molecules. Blood (2005) 1.27
[5C + 1N] annulation: a novel synthetic strategy for functionalized 2,3-dihydro-4-pyridones. Chem Commun (Camb) (2005) 1.26
Metabolites of organophosphate flame retardants and 2-ethylhexyl tetrabromobenzoate in urine from paired mothers and toddlers. Environ Sci Technol (2014) 1.25
CD molecules 2006--human cell differentiation molecules. J Immunol Methods (2006) 1.23
The PD-1/PD-L1 axis contributes to T-cell dysfunction in chronic lymphocytic leukemia. Haematologica (2013) 1.21
CD38 orchestrates migration, survival, and Th1 immune response of human mature dendritic cells. Blood (2005) 1.20
Plasma miRNAs as diagnostic and prognostic biomarkers for ovarian cancer. PLoS One (2013) 1.20
Crystal structure of the cysteine-rich secretory protein stecrisp reveals that the cysteine-rich domain has a K+ channel inhibitor-like fold. J Biol Chem (2004) 1.20
Clickable NAD analogues for labeling substrate proteins of poly(ADP-ribose) polymerases. J Am Chem Soc (2010) 1.18
Identification of lysine succinylation substrates and the succinylation regulatory enzyme CobB in Escherichia coli. Mol Cell Proteomics (2013) 1.17
Isolation and characterization of Toxoplasma gondii strains from stray cats revealed a single genotype in Beijing, China. Vet Parasitol (2012) 1.17
Multilayer X-ray optics at CHESS. J Synchrotron Radiat (2006) 1.17
Structure of Crimean-Congo hemorrhagic fever virus nucleoprotein: superhelical homo-oligomers and the role of caspase-3 cleavage. J Virol (2012) 1.16
A MAPK-positive feedback mechanism for BLR1 signaling propels retinoic acid-triggered differentiation and cell cycle arrest. J Biol Chem (2007) 1.16
Impact of sodium and ultrafiltration profiling on haemodialysis-related hypotension. Nephrol Dial Transplant (2006) 1.15
Transient decrease in F-actin may be necessary for translocation of proteins into dendritic spines. Eur J Neurosci (2005) 1.15
Nicotinamide blocks proliferation and induces apoptosis of chronic lymphocytic leukemia cells through activation of the p53/miR-34a/SIRT1 tumor suppressor network. Cancer Res (2011) 1.13
Acidic residues at the active sites of CD38 and ADP-ribosyl cyclase determine nicotinic acid adenine dinucleotide phosphate (NAADP) synthesis and hydrolysis activities. J Biol Chem (2006) 1.13
Synthesis and biological evaluation of thiol-based inhibitors of glutamate carboxypeptidase II: discovery of an orally active GCP II inhibitor. J Med Chem (2003) 1.12
CD38 is expressed on human mature monocyte-derived dendritic cells and is functionally involved in CD83 expression and IL-12 induction. Eur J Immunol (2004) 1.11
CD38/CD19: a lipid raft-dependent signaling complex in human B cells. Blood (2007) 1.11
Tandem double-Michael-addition/cyclization/acyl migration of 1,4-dien-3-ones and ethyl isocyanoacetate: stereoselective synthesis of pyrrolizidines. Angew Chem Int Ed Engl (2009) 1.11
A nitrogen budget of the Changjiang river catchment. Ambio (2003) 1.11
CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death. Blood (2011) 1.09
Enzymatic tailoring of enterobactin alters membrane partitioning and iron acquisition. ACS Chem Biol (2006) 1.09
A randomized comparative trial between Acticoat and SD-Ag in the treatment of residual burn wounds, including safety analysis. Burns (2006) 1.08
A CD38/CD203a/CD73 ectoenzymatic pathway independent of CD39 drives a novel adenosinergic loop in human T lymphocytes. Oncoimmunology (2013) 1.07
Domino ring-opening/recyclization reactions of doubly activated cyclopropanes as a strategy for the synthesis of furoquinoline derivatives. Angew Chem Int Ed Engl (2007) 1.07
Activation of the aryl hydrocarbon receptor AhR Promotes retinoic acid-induced differentiation of myeloblastic leukemia cells by restricting expression of the stem cell transcription factor Oct4. Cancer Res (2011) 1.07
Chemical complementation: a reaction-independent genetic assay for enzyme catalysis. Proc Natl Acad Sci U S A (2002) 1.07
Arsenic trioxide and breast cancer: analysis of the apoptotic, differentiative and immunomodulatory effects. Breast Cancer Res Treat (2002) 1.07
Blocking effect and crystal structure of natrin toxin, a cysteine-rich secretory protein from Naja atra venom that targets the BKCa channel. Biochemistry (2005) 1.07
Exosomes from human lymphoblastoid B cells express enzymatically active CD38 that is associated with signaling complexes containing CD81, Hsc-70 and Lyn. Exp Cell Res (2010) 1.06
Cyclic ADP-ribose is a second messenger in the lipopolysaccharide-stimulated proliferation of human peripheral blood mononuclear cells. Biochem J (2003) 1.06
CD38 signaling in T cells is initiated within a subset of membrane rafts containing Lck and the CD3-zeta subunit of the T cell antigen receptor. J Biol Chem (2003) 1.05
The membrane-bound enzyme CD38 exists in two opposing orientations. Sci Signal (2012) 1.04
Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis. J Biol Chem (2006) 1.03
Crystal structure of the ligand binding domain of netrin G2. J Mol Biol (2011) 1.03
IFN-gamma arms human dendritic cells to perform multiple effector functions. J Immunol (2008) 1.03
CD38 is associated with lipid rafts and upon receptor stimulation leads to Akt/protein kinase B and Erk activation in the absence of the CD3-zeta immune receptor tyrosine-based activation motifs. J Biol Chem (2001) 1.03
Retinoic acid-induced CD38 expression in HL-60 myeloblastic leukemia cells regulates cell differentiation or viability depending on expression levels. J Cell Biochem (2006) 1.02
MiR-145 is downregulated in human ovarian cancer and modulates cell growth and invasion by targeting p70S6K1 and MUC1. Biochem Biophys Res Commun (2013) 1.02
c-Cbl interacts with CD38 and promotes retinoic acid-induced differentiation and G0 arrest of human myeloblastic leukemia cells. Cancer Res (2008) 1.02
Oct-4+/Tenascin C+ neuroblastoma cells serve as progenitors of tumor-derived endothelial cells. Cell Res (2011) 1.02
High-pressure cryocooling for capillary sample cryoprotection and diffraction phasing at long wavelengths. Acta Crystallogr D Biol Crystallogr (2007) 1.01
Solution of protein crystallographic structures by high-pressure cryocooling and noble-gas phasing. Acta Crystallogr D Biol Crystallogr (2006) 1.01
Crystal structures of Fms1 and its complex with spermine reveal substrate specificity. J Mol Biol (2005) 1.01
CD38 and CD157: a long journey from activation markers to multifunctional molecules. Cytometry B Clin Cytom (2013) 1.01
Expression of ribosomal and translation-associated genes is correlated with a favorable clinical course in chronic lymphocytic leukemia. Blood (2002) 1.00
Metabolic characterization of a Sirt5 deficient mouse model. Sci Rep (2013) 1.00
6-Shogaol induces apoptosis in human hepatocellular carcinoma cells and exhibits anti-tumor activity in vivo through endoplasmic reticulum stress. PLoS One (2012) 1.00