Published in J Gen Physiol on July 14, 2003
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Cerebrovascular responses in mice deficient in the potassium channel, TREK-1. Am J Physiol Regul Integr Comp Physiol (2010) 1.54
Proximal renal tubular acidosis in TASK2 K+ channel-deficient mice reveals a mechanism for stabilizing bicarbonate transport. Proc Natl Acad Sci U S A (2004) 1.40
ARF6-dependent interaction of the TWIK1 K+ channel with EFA6, a GDP/GTP exchange factor for ARF6. EMBO Rep (2004) 1.37
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The two-pore domain potassium channel KCNK5: induction by estrogen receptor alpha and role in proliferation of breast cancer cells. Mol Endocrinol (2011) 0.89
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Mechanoprotection by polycystins against apoptosis is mediated through the opening of stretch-activated K(2P) channels. Cell Rep (2012) 0.86
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The two-pore domain potassium channel KCNK5 deteriorates outcome in ischemic neurodegeneration. Pflugers Arch (2014) 0.77
Potassium channels in pancreatic duct epithelial cells: their role, function and pathophysiological relevance. Pflugers Arch (2014) 0.76
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Phosphatidylinositol (4,5)-bisphosphate dynamically regulates the K2P background K(+) channel TASK-2. Sci Rep (2017) 0.75
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Intracellular signalling involved in volume regulatory decrease. Cell Physiol Biochem (2000) 1.02
Mutation of KCNK5 or Kir3.2 potassium channels in mice does not change minimum alveolar anesthetic concentration. Anesth Analg (2003) 0.97
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CFTR null mutation altered cAMP-sensitive and swelling-activated Cl- currents in primary cultures of mouse nephron. Am J Physiol Renal Physiol (2002) 0.91
Intracellular signalling involved in activation of the volume-sensitive K+ current in Ehrlich ascites tumour cells. Comp Biochem Physiol A Mol Integr Physiol (2001) 0.89
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K+ conductance activated during regulatory volume decrease. The channels in Ehrlich cells and their possible molecular counterpart. Comp Biochem Physiol A Mol Integr Physiol (2001) 0.86
Extracellular adenosine modulates a volume-sensitive-like chloride conductance in immortalized rabbit DC1 cells. Am J Physiol Renal Physiol (2001) 0.83
Fluorescent video-microscopy study of regulatory volume decrease in primary culture of rabbit proximal convoluted tubule. Biochim Biophys Acta (1990) 0.82
Polarized 86Rb+ effluxes in primary cultures of rabbit kidney proximal cells: role of calcium and hypotonicity. Biochim Biophys Acta (1990) 0.81
KCNQ1 gain-of-function mutation in familial atrial fibrillation. Science (2003) 6.60
Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activity. Cancer Res (2006) 2.87
Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype. Nat Neurosci (2006) 2.75
Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation. Am J Hum Genet (2004) 2.66
A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation. Biochem Biophys Res Commun (2005) 2.55
The epidermal barrier function is dependent on the serine protease CAP1/Prss8. J Cell Biol (2005) 2.36
International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels. Pharmacol Rev (2003) 2.05
International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels. Pharmacol Rev (2005) 2.03
TREK-1, a K+ channel involved in polymodal pain perception. EMBO J (2006) 2.02
The mechano-activated K+ channels TRAAK and TREK-1 control both warm and cold perception. EMBO J (2009) 1.98
Specific Cre/Lox recombination in the mouse proximal tubule. J Am Soc Nephrol (2004) 1.84
The 5-HT3 subtype of serotonin receptor contributes to nociceptive processing via a novel subset of myelinated and unmyelinated nociceptors. J Neurosci (2002) 1.82
SLCO4C1 transporter eliminates uremic toxins and attenuates hypertension and renal inflammation. J Am Soc Nephrol (2009) 1.70
In vitro molecular interactions and distribution of KCNE family with KCNQ1 in the human heart. Cardiovasc Res (2005) 1.68
Mechanisms underlying excitatory effects of group I metabotropic glutamate receptors via inhibition of 2P domain K+ channels. EMBO J (2003) 1.65
CFTR mediates cadmium-induced apoptosis through modulation of ROS level in mouse proximal tubule cells. Free Radic Biol Med (2008) 1.60
Intrarenal transfer of an intracellular fluorescent fusion of angiotensin II selectively in proximal tubules increases blood pressure in rats and mice. Am J Physiol Renal Physiol (2011) 1.59
Invalidation of TASK1 potassium channels disrupts adrenal gland zonation and mineralocorticoid homeostasis. EMBO J (2007) 1.53
Control of the autophagy maturation step by the MAPK ERK and p38: lessons from environmental carcinogens. Autophagy (2007) 1.50
Effect of heavy metals on, and handling by, the kidney. Nephron Physiol (2005) 1.49
Heteromeric KCNE2/KCNQ1 potassium channels in the luminal membrane of gastric parietal cells. J Physiol (2004) 1.46
The pig as a preclinical model for intestinal ischemia-reperfusion and transplantation studies. J Surg Res (2012) 1.44
Cross-talk between the mechano-gated K2P channel TREK-1 and the actin cytoskeleton. EMBO Rep (2005) 1.41
Proximal renal tubular acidosis in TASK2 K+ channel-deficient mice reveals a mechanism for stabilizing bicarbonate transport. Proc Natl Acad Sci U S A (2004) 1.40
ARF6-dependent interaction of the TWIK1 K+ channel with EFA6, a GDP/GTP exchange factor for ARF6. EMBO Rep (2004) 1.37
Task2 potassium channels set central respiratory CO2 and O2 sensitivity. Proc Natl Acad Sci U S A (2010) 1.36
Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue. Proc Natl Acad Sci U S A (2009) 1.31
Acid-sensing ion channel 2 is important for retinal function and protects against light-induced retinal degeneration. J Neurosci (2004) 1.29
The renal segmental distribution of claudins changes with development. Kidney Int (2002) 1.25
AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K(+) channels into open leak channels. EMBO J (2006) 1.24
Potassium channel silencing by constitutive endocytosis and intracellular sequestration. J Biol Chem (2009) 1.17
Altered acetylcholine, bradykinin and cutaneous pressure-induced vasodilation in mice lacking the TREK1 potassium channel: the endothelial link. EMBO Rep (2007) 1.17
GluR7 is an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses. Proc Natl Acad Sci U S A (2007) 1.16
The multifaceted phenotype of the knockout mouse for the KCNE1 potassium channel gene. Am J Physiol Regul Integr Comp Physiol (2002) 1.15
Disruption of the K+ channel beta-subunit KCNE3 reveals an important role in intestinal and tracheal Cl- transport. J Biol Chem (2010) 1.15
Mtap2 is a constituent of the protein network that regulates twik-related K+ channel expression and trafficking. J Neurosci (2008) 1.12
Molecular regulations governing TREK and TRAAK channel functions. Channels (Austin) (2011) 1.11
Does sumoylation control K2P1/TWIK1 background K+ channels? Cell (2007) 1.10
TWIK1, a unique background channel with variable ion selectivity. Proc Natl Acad Sci U S A (2012) 1.09
Molecular physiology of pH-sensitive background K(2P) channels. Physiology (Bethesda) (2011) 1.07
Breathing with phox2b. Philos Trans R Soc Lond B Biol Sci (2009) 1.05
Conditional gene targeting of the Scnn1a (alphaENaC) gene locus. Genesis (2002) 1.04
TASK-2 channels contribute to pH sensitivity of retrotrapezoid nucleus chemoreceptor neurons. J Neurosci (2013) 1.03
Piezo1-dependent stretch-activated channels are inhibited by Polycystin-2 in renal tubular epithelial cells. EMBO Rep (2013) 1.02
Glucose inhibition persists in hypothalamic neurons lacking tandem-pore K+ channels. J Neurosci (2009) 1.02
Kv1.1 channels act as mechanical brake in the senses of touch and pain. Neuron (2013) 1.01
Molecular characterization of two founder mutations causing long QT syndrome and identification of compound heterozygous patients. Ann Med (2006) 1.01
Torsades de pointes complicating atrioventricular block: evidence for a genetic predisposition. Heart Rhythm (2006) 1.00
Expression and insights on function of potassium channel TWIK-1 in mouse kidney. Pflugers Arch (2005) 1.00
Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability. Cancer Res (2013) 0.97
Glycosylphosphatidylinositol-anchored proteins and actin cytoskeleton modulate chloride transport by channels formed by the Helicobacter pylori vacuolating cytotoxin VacA in HeLa cells. J Biol Chem (2003) 0.95
CFTR-dependent and -independent swelling-activated K+ currents in primary cultures of mouse nephron. Am J Physiol Renal Physiol (2002) 0.94
CFTR mediates apoptotic volume decrease and cell death by controlling glutathione efflux and ROS production in cultured mice proximal tubules. Am J Physiol Renal Physiol (2009) 0.94
Antiepileptic popular ketogenic diet: emerging twists in an ancient story. Prog Neurobiol (2005) 0.93
Proximal tubule specific knockout of the Na⁺/H⁺ exchanger NHE3: effects on bicarbonate absorption and ammonium excretion. J Mol Med (Berl) (2013) 0.93
Role of TASK2 in the control of apoptotic volume decrease in proximal kidney cells. J Biol Chem (2007) 0.93
Cadmium-induced autophagy in rat kidney: an early biomarker of subtoxic exposure. Toxicol Sci (2011) 0.93
The channel-activating protease CAP1/Prss8 is required for placental labyrinth maturation. PLoS One (2013) 0.92
Nongenomic effects of cisplatin: acute inhibition of mechanosensitive transporters and channels without actin remodeling. Cancer Res (2010) 0.92
CFTR null mutation altered cAMP-sensitive and swelling-activated Cl- currents in primary cultures of mouse nephron. Am J Physiol Renal Physiol (2002) 0.91