Cerebrovascular responses in mice deficient in the potassium channel, TREK-1.

PubWeight™: 1.54‹?› | Rank: Top 4%

🔗 View Article (PMC 2928619)

Published in Am J Physiol Regul Integr Comp Physiol on March 31, 2010

Authors

Khodadad Namiranian1, Eric E Lloyd, Randy F Crossland, Sean P Marrelli, George E Taffet, Anilkumar K Reddy, Craig J Hartley, Robert M Bryan

Author Affiliations

1: Department of Anesthesiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

Articles citing this

Participation of KCNQ (Kv7) potassium channels in myogenic control of cerebral arterial diameter. J Physiol (2010) 1.43

Endothelial TWIK-related potassium channel-1 (TREK1) regulates immune-cell trafficking into the CNS. Nat Med (2013) 1.10

Activation of endothelial transient receptor potential C3 channel is required for small conductance calcium-activated potassium channel activation and sustained endothelial hyperpolarization and vasodilation of cerebral artery. J Am Heart Assoc (2014) 0.83

Temperature sensitivity of two-pore (K2P) potassium channels. Curr Top Membr (2014) 0.82

Alterations of N-3 polyunsaturated fatty acid-activated K2P channels in hypoxia-induced pulmonary hypertension. Basic Clin Pharmacol Toxicol (2013) 0.81

Genetic Deletion of TREK-1 or TWIK-1/TREK-1 Potassium Channels does not Alter the Basic Electrophysiological Properties of Mature Hippocampal Astrocytes In Situ. Front Cell Neurosci (2016) 0.79

Traumatic brain injury in mice lacking the K channel, TREK-1. J Cereb Blood Flow Metab (2010) 0.78

A role for TREK1 in generating the slow afterhyperpolarization in developing starburst amacrine cells. J Neurophysiol (2013) 0.78

Protein kinase A and C regulate leak potassium currents in freshly isolated vascular myocytes from the aorta. PLoS One (2013) 0.75

The role of TREK-1 in cerebrovascular regulation remains elusive: focus on "Cerebrovascular responses in mice deficient in the potassium channel, TREK-1". Am J Physiol Regul Integr Comp Physiol (2010) 0.75

Articles cited by this

Nitric oxide and peroxynitrite in health and disease. Physiol Rev (2007) 15.49

Physiological roles and properties of potassium channels in arterial smooth muscle. Am J Physiol (1995) 7.98

Physiology of cell volume regulation in vertebrates. Physiol Rev (2009) 5.11

Functional significance of cell volume regulatory mechanisms. Physiol Rev (1998) 4.59

Inhalational anesthetics activate two-pore-domain background K+ channels. Nat Neurosci (1999) 3.73

A mammalian two pore domain mechano-gated S-like K+ channel. EMBO J (1998) 3.58

Calcium-activated potassium channels and the regulation of vascular tone. Physiology (Bethesda) (2006) 3.25

Regulation of the cerebral circulation: role of endothelium and potassium channels. Physiol Rev (1998) 2.98

TREK-1, a K+ channel involved in neuroprotection and general anesthesia. EMBO J (2004) 2.85

Properties and modulation of mammalian 2P domain K+ channels. Trends Neurosci (2001) 2.68

A neuronal two P domain K+ channel stimulated by arachidonic acid and polyunsaturated fatty acids. EMBO J (1998) 2.55

Potassium channels in the peripheral microcirculation. Microcirculation (2005) 2.34

Alternative translation initiation in rat brain yields K2P2.1 potassium channels permeable to sodium. Neuron (2008) 2.21

The stretch-activated potassium channel TREK-1 in rat cardiac ventricular muscle. Cardiovasc Res (2005) 2.14

Lipid and mechano-gated 2P domain K(+) channels. Curr Opin Cell Biol (2001) 2.12

International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels. Pharmacol Rev (2005) 2.03

Polyunsaturated fatty acids are cerebral vasodilators via the TREK-1 potassium channel. Circ Res (2007) 2.02

Genetic manipulation of cardiac K(+) channel function in mice: what have we learned, and where do we go from here? Circ Res (2001) 1.66

K+-dependent cerebellar granule neuron apoptosis. Role of task leak K+ channels. J Biol Chem (2003) 1.56

Two-pore domain K channel, TASK-1, in pulmonary artery smooth muscle cells. Circ Res (2003) 1.53

Impact of TASK-1 in human pulmonary artery smooth muscle cells. Circ Res (2006) 1.44

Enzymatic isolation and characterization of single vascular smooth muscle cells from cremasteric arterioles. Microcirculation (1997) 1.30

Functional evidence of a role for two-pore domain potassium channels in rat mesenteric and pulmonary arteries. Br J Pharmacol (2004) 1.29

Effects of isoflurane on coronary blood flow velocity in young, old and ApoE(-/-) mice measured by Doppler ultrasound. Ultrasound Med Biol (2007) 1.29

Pulsed Doppler signal processing for use in mice: applications. IEEE Trans Biomed Eng (2005) 1.28

TWIK-2, an inactivating 2P domain K+ channel. J Biol Chem (2000) 1.26

Fatty acid-sensitive two-pore domain K+ channels. Trends Pharmacol Sci (2003) 1.25

Functional heterogeneity of endothelial P2 purinoceptors in the cerebrovascular tree of the rat. Am J Physiol (1999) 1.22

Two-pore potassium channels in the cardiovascular system. Eur Biophys J (2008) 1.21

THIK-1 and THIK-2, a novel subfamily of tandem pore domain K+ channels. J Biol Chem (2000) 1.20

Endothelium-derived hyperpolarizing factor: a cousin to nitric oxide and prostacyclin. Anesthesiology (2005) 1.17

Altered acetylcholine, bradykinin and cutaneous pressure-induced vasodilation in mice lacking the TREK1 potassium channel: the endothelial link. EMBO Rep (2007) 1.17

Role of TASK2 potassium channels regarding volume regulation in primary cultures of mouse proximal tubules. J Gen Physiol (2003) 1.16

Background and tandem-pore potassium channels in magnocellular neurosecretory cells of the rat supraoptic nucleus. J Physiol (2003) 1.12

Evidence for two-pore domain potassium channels in rat cerebral arteries. Am J Physiol Heart Circ Physiol (2006) 1.11

Tandem-pore domain potassium channels are functionally expressed in retinal (Müller) glial cells. Glia (2006) 1.08

Effects of luminal shear stress on cerebral arteries and arterioles. Am J Physiol Heart Circ Physiol (2001) 1.08

P2u receptor-mediated release of endothelium-derived relaxing factor/nitric oxide and endothelium-derived hyperpolarizing factor from cerebrovascular endothelium in rats. Stroke (1999) 1.05

Effects of carbon monoxide and heme oxygenase inhibitors in cerebral vessels of rats and mice. Am J Physiol Heart Circ Physiol (2006) 1.00

Apoptosis recruits two-pore domain potassium channels used for homeostatic volume regulation. Am J Physiol Cell Physiol (2002) 1.00

TREK-1 K+ channels couple angiotensin II receptors to membrane depolarization and aldosterone secretion in bovine adrenal glomerulosa cells. Am J Physiol Endocrinol Metab (2004) 0.97

Investigation of the role of TASK-2 channels in rat pulmonary arteries; pharmacological and functional studies following RNA interference procedures. Br J Pharmacol (2006) 0.97

A cellular model for long QT syndrome. Trapping of heteromultimeric complexes consisting of truncated Kv1.1 potassium channel polypeptides and native Kv1.4 and Kv1.5 channels in the endoplasmic reticulum. J Biol Chem (1997) 0.96

Role of TASK2 in the control of apoptotic volume decrease in proximal kidney cells. J Biol Chem (2007) 0.93

Starring TREK-1: the next generation of vascular K+ channels. Circ Res (2007) 0.92

Arachidonic acid metabolites, hydrogen peroxide, and EDHF in cerebral arteries. Am J Physiol Heart Circ Physiol (2005) 0.92

Stimulation of alpha 2 adrenoceptors dilates the rat middle cerebral artery. Anesthesiology (1996) 0.91

Characterization of TWIK-2, a two-pore domain K+ channel, cloned from the rat middle cerebral artery. Exp Biol Med (Maywood) (2009) 0.91

Stretch-activated potassium channels in hypotonically induced blebs of atrial myocytes. J Membr Biol (2008) 0.90

Delayed rectifier outward K+ current mediates the migration of rat cerebellar granule cells stimulated by melatonin. J Neurochem (2007) 0.90

Modulation of native TREK-1 and Kv1.4 K+ channels by polyunsaturated fatty acids and lysophospholipids. J Membr Biol (2003) 0.89

Role of cytoplasmic phospholipase A2 in endothelium-derived hyperpolarizing factor dilations of rat middle cerebral arteries. J Cereb Blood Flow Metab (2002) 0.89

A truncated Kv1.1 protein in the brain of the megencephaly mouse: expression and interaction. BMC Neurosci (2005) 0.88

Potassium channels and proliferation of vascular smooth muscle cells. Circ Res (2005) 0.87

cGMP does not activate two-pore domain K+ channels in cerebrovascular smooth muscle. Am J Physiol Heart Circ Physiol (2009) 0.79

Articles by these authors

One versus two venous anastomoses in microvascular free flap surgery. Plast Reconstr Surg (2010) 2.20

Novel approaches to perioperative assessment and intervention may improve long-term outcomes after colorectal cancer resection in older adults. Ann Surg (2011) 2.16

Targeted deletion of microRNA-22 promotes stress-induced cardiac dilation and contractile dysfunction. Circulation (2012) 2.14

A pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway. Proc Natl Acad Sci U S A (2006) 2.03

Targeted deletion of ROCK1 protects the heart against pressure overload by inhibiting reactive fibrosis. FASEB J (2006) 1.99

Mice with the R176Q cardiac ryanodine receptor mutation exhibit catecholamine-induced ventricular tachycardia and cardiomyopathy. Proc Natl Acad Sci U S A (2006) 1.85

In vitro validation of real-time three-dimensional color Doppler echocardiography for direct measurement of proximal isovelocity surface area in mitral regurgitation. Am J Cardiol (2007) 1.81

A novel feature-tracking echocardiographic method for the quantitation of regional myocardial function: validation in an animal model of ischemia-reperfusion. J Am Coll Cardiol (2008) 1.79

TNF provokes cardiomyocyte apoptosis and cardiac remodeling through activation of multiple cell death pathways. J Clin Invest (2007) 1.75

Monocytic fibroblast precursors mediate fibrosis in angiotensin-II-induced cardiac hypertrophy. J Mol Cell Cardiol (2010) 1.73

Activation of cardiac Cdk9 represses PGC-1 and confers a predisposition to heart failure. EMBO J (2004) 1.62

Endothelial influences on cerebrovascular tone. J Appl Physiol (1985) (2006) 1.61

Transient receptor potential canonical type 3 channels facilitate endothelium-derived hyperpolarization-mediated resistance artery vasodilator activity. Cardiovasc Res (2012) 1.56

Requirement of argininosuccinate lyase for systemic nitric oxide production. Nat Med (2011) 1.54

Hyperhomocystinemia impairs endothelial function and eNOS activity via PKC activation. Arterioscler Thromb Vasc Biol (2005) 1.52

Disruption of K(2P)6.1 produces vascular dysfunction and hypertension in mice. Hypertension (2011) 1.49

Measurement of aortic input impedance in mice: effects of age on aortic stiffness. Am J Physiol Heart Circ Physiol (2003) 1.46

PLA2 and TRPV4 channels regulate endothelial calcium in cerebral arteries. Am J Physiol Heart Circ Physiol (2006) 1.44

Bedside-to-Bench conference: research agenda for idiopathic fatigue and aging. J Am Geriatr Soc (2010) 1.41

Doppler estimation of reduced coronary flow reserve in mice with pressure overload cardiac hypertrophy. Ultrasound Med Biol (2008) 1.40

Trigeminal trophic syndrome. South Med J (2007) 1.40

Telomere attrition and Chk2 activation in human heart failure. Proc Natl Acad Sci U S A (2003) 1.37

Transgenic mouse model of ventricular preexcitation and atrioventricular reentrant tachycardia induced by an AMP-activated protein kinase loss-of-function mutation responsible for Wolff-Parkinson-White syndrome. Circulation (2004) 1.35

Immune-inflammatory dysregulation modulates the incidence of progressive fibrosis and diastolic stiffness in the aging heart. J Mol Cell Cardiol (2010) 1.34

Bcl-2 overexpression corrects mitochondrial defects and ameliorates inherited desmin null cardiomyopathy. Proc Natl Acad Sci U S A (2004) 1.29

Effects of isoflurane on coronary blood flow velocity in young, old and ApoE(-/-) mice measured by Doppler ultrasound. Ultrasound Med Biol (2007) 1.29

Pulsed Doppler signal processing for use in mice: applications. IEEE Trans Biomed Eng (2005) 1.28

Effects of diet-induced obesity on inflammation and remodeling after myocardial infarction. Am J Physiol Heart Circ Physiol (2006) 1.27

Cardiomyocyte PDGFR-beta signaling is an essential component of the mouse cardiac response to load-induced stress. J Clin Invest (2010) 1.25

H2O2 activates redox- and 4-aminopyridine-sensitive Kv channels in coronary vascular smooth muscle. Am J Physiol Heart Circ Physiol (2006) 1.24

KIR channels function as electrical amplifiers in rat vascular smooth muscle. J Physiol (2007) 1.20

Heart failure and greater infarct expansion in middle-aged mice: a relevant model for postinfarction failure. Am J Physiol Heart Circ Physiol (2002) 1.20

Endothelium-derived hyperpolarizing factor: a cousin to nitric oxide and prostacyclin. Anesthesiology (2005) 1.17

CCR2 mediates the uptake of bone marrow-derived fibroblast precursors in angiotensin II-induced cardiac fibrosis. Am J Physiol Heart Circ Physiol (2011) 1.14

Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation. Am J Clin Nutr (2011) 1.14

Noninvasive cardiovascular phenotyping in mice. ILAR J (2002) 1.12

Importance of pulsatility in hypertensive carotid artery growth and remodeling. J Hypertens (2009) 1.11

Evidence for two-pore domain potassium channels in rat cerebral arteries. Am J Physiol Heart Circ Physiol (2006) 1.11

MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq. Proc Natl Acad Sci U S A (2002) 1.11

Three-dimensional color Doppler echocardiography for direct measurement of vena contracta area in mitral regurgitation: in vitro validation and clinical experience. JACC Cardiovasc Imaging (2008) 1.11

Load-dependent and -independent regulation of proinflammatory cytokine and cytokine receptor gene expression in the adult mammalian heart. Circulation (2002) 1.09

Regulatable atrial natriuretic peptide gene therapy for hypertension. Proc Natl Acad Sci U S A (2005) 1.09

TNF receptor 1 signaling is critically involved in mediating angiotensin-II-induced cardiac fibrosis. J Mol Cell Cardiol (2013) 1.08

Cerebrovascular consequences of obstructive sleep apnea. J Am Heart Assoc (2012) 1.07

Doppler evaluation of peripheral vascular adaptations to transverse aortic banding in mice. Ultrasound Med Biol (2003) 1.06

Inhibition of TRPC1/TRPC3 by PKG contributes to NO-mediated vasorelaxation. Am J Physiol Heart Circ Physiol (2009) 1.04

Dynamics of dense electronegative low density lipoproteins and their preferential association with lipoprotein phospholipase A(2). J Lipid Res (2006) 1.03

Determinants of cardiac electrophysiological properties in mice. J Interv Card Electrophysiol (2004) 1.02

Cardiac function in young and old Little mice. J Gerontol A Biol Sci Med Sci (2007) 1.01

Effects of carbon monoxide and heme oxygenase inhibitors in cerebral vessels of rats and mice. Am J Physiol Heart Circ Physiol (2006) 1.00

Effect of age on peripheral vascular response to transverse aortic banding in mice. J Gerontol A Biol Sci Med Sci (2003) 0.99

Vasa vasorum imaging: a new window to the clinical detection of vulnerable atherosclerotic plaques. Curr Atheroscler Rep (2005) 0.99

Endothelium-derived hyperpolarizing factor in the brain: a new regulator of cerebral blood flow? Stroke (2002) 0.99

Nitric-oxide supplementation for treatment of long-term complications in argininosuccinic aciduria. Am J Hum Genet (2012) 0.98

Blood flow in compliant arteries: an effective viscoelastic reduced model, numerics, and experimental validation. Ann Biomed Eng (2006) 0.97

SRC-2 coactivator deficiency decreases functional reserve in response to pressure overload of mouse heart. PLoS One (2012) 0.96

microRNA-22 promotes heart failure through coordinate suppression of PPAR/ERR-nuclear hormone receptor transcription. PLoS One (2013) 0.96

Disruption of Rho signaling results in progressive atrioventricular conduction defects while ventricular function remains preserved. FASEB J (2004) 0.93

Pulsed Doppler signal processing for use in mice: design and evaluation. IEEE Trans Biomed Eng (2005) 0.93

Starring TREK-1: the next generation of vascular K+ channels. Circ Res (2007) 0.92

Arachidonic acid metabolites, hydrogen peroxide, and EDHF in cerebral arteries. Am J Physiol Heart Circ Physiol (2005) 0.92

Multichannel pulsed Doppler signal processing for vascular measurements in mice. Ultrasound Med Biol (2009) 0.92

Characterization of TWIK-2, a two-pore domain K+ channel, cloned from the rat middle cerebral artery. Exp Biol Med (Maywood) (2009) 0.91

Aberrant differentiation of fibroblast progenitors contributes to fibrosis in the aged murine heart: role of elevated circulating insulin levels. FASEB J (2013) 0.91

A new rodent model for obstructive sleep apnea: effects on ATP-mediated dilations in cerebral arteries. Am J Physiol Regul Integr Comp Physiol (2013) 0.91

Vascular and parenchymal amyloid pathology in an Alzheimer disease knock-in mouse model: interplay with cerebral blood flow. Mol Neurodegener (2014) 0.91

Simulated microgravity enhances cerebral artery vasoconstriction and vascular resistance through endothelial nitric oxide mechanism. Am J Physiol Heart Circ Physiol (2004) 0.90

Doppler velocity measurements from large and small arteries of mice. Am J Physiol Heart Circ Physiol (2011) 0.90

The myogenic response in isolated rat cerebrovascular arteries: smooth muscle cell model. Med Eng Phys (2003) 0.90