Published in Neuron on March 06, 2013
Ankyrin Repeats Convey Force to Gate the NOMPC Mechanotransduction Channel. Cell (2015) 1.62
Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K+ channels. Proc Natl Acad Sci U S A (2014) 1.34
Feeling the hidden mechanical forces in lipid bilayer is an original sense. Proc Natl Acad Sci U S A (2014) 1.22
Opening paths to novel analgesics: the role of potassium channels in chronic pain. Trends Neurosci (2014) 1.16
Mechanically Activated Ion Channels. Neuron (2015) 1.07
Comprehensive RNA-Seq expression analysis of sensory ganglia with a focus on ion channels and GPCRs in Trigeminal ganglia. PLoS One (2013) 1.06
The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements. Pflugers Arch (2014) 1.00
Phospholipids that contain polyunsaturated fatty acids enhance neuronal cell mechanics and touch sensation. Cell Rep (2014) 0.93
Heterogeneous intrinsic excitability of murine spiral ganglion neurons is determined by Kv1 and HCN channels. Neuroscience (2013) 0.90
Mechanical allodynia. Pflugers Arch (2014) 0.90
Epigenetic modification of DRG neuronal gene expression subsequent to nerve injury: etiological contribution to complex regional pain syndromes (Part I). Med Sci Monit (2014) 0.86
Stimulation-induced ectopicity and propagation windows in model damaged axons. J Comput Neurosci (2014) 0.82
Novel cell-free high-throughput screening method for pharmacological tools targeting K+ channels. Proc Natl Acad Sci U S A (2016) 0.82
Transduction and encoding sensory information by skin mechanoreceptors. Pflugers Arch (2014) 0.82
Nociceptor Sensitization Depends on Age and Pain Chronicity(1,2,3). eNeuro (2016) 0.81
Physiological and pathological functions of mechanosensitive ion channels. Mol Neurobiol (2014) 0.80
Localized force application reveals mechanically sensitive domains of Piezo1. Nat Commun (2016) 0.79
Genomewide analysis of rat periaqueductal gray-dorsal horn reveals time-, region- and frequency-specific mRNA expression changes in response to electroacupuncture stimulation. Sci Rep (2014) 0.79
Phosphoinositide signaling in somatosensory neurons. Adv Biol Regul (2015) 0.76
The Hv1 proton channel responds to mechanical stimuli. J Gen Physiol (2016) 0.76
Mechanosensitive gating of Kv channels. PLoS One (2015) 0.76
Transduction of Repetitive Mechanical Stimuli by Piezo1 and Piezo2 Ion Channels. Cell Rep (2017) 0.75
Mechanosensitive Ion Channels in Cardiovascular Physiology. Exp Clin Cardiol (2014) 0.75
Altered potassium channel distribution and composition in myelinated axons suppresses hyperexcitability following injury. Elife (2016) 0.75
Unmasking of spiral ganglion neuron firing dynamics by membrane potential and neurotrophin-3. J Neurosci (2014) 0.75
MicroRNA cluster miR-17-92 regulates multiple functionally related voltage-gated potassium channels in chronic neuropathic pain. Nat Commun (2017) 0.75
Polycystin-1 and -2 dosage regulates pressure sensing. Cell (2009) 3.36
ASIC3, a sensor of acidic and primary inflammatory pain. EMBO J (2008) 2.18
Endothelial and steroidogenic cell migration are regulated by WNT4 in the developing mammalian gonad. Development (2003) 2.10
International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels. Pharmacol Rev (2003) 2.05
International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels. Pharmacol Rev (2005) 2.03
TREK-1, a K+ channel involved in polymodal pain perception. EMBO J (2006) 2.02
Acid-sensing ion channels (ASICs): pharmacology and implication in pain. Pharmacol Ther (2010) 1.92
Formation of a new receptor-operated channel by heteromeric assembly of TRPP2 and TRPC1 subunits. EMBO Rep (2008) 1.73
Pharmacological dissection and distribution of NaN/Nav1.9, T-type Ca2+ currents, and mechanically activated cation currents in different populations of DRG neurons. J Gen Physiol (2007) 1.69
Mechanisms underlying excitatory effects of group I metabotropic glutamate receptors via inhibition of 2P domain K+ channels. EMBO J (2003) 1.65
Invalidation of TASK1 potassium channels disrupts adrenal gland zonation and mineralocorticoid homeostasis. EMBO J (2007) 1.53
Menthol pain relief through cumulative inactivation of voltage-gated sodium channels. Pain (2011) 1.51
Multigenic control of disease severity after virulent Mycobacterium tuberculosis infection in mice. Infect Immun (2003) 1.48
Genetic polymorphisms in monoamine systems and outcome of cognitive behavior therapy for social anxiety disorder. PLoS One (2013) 1.44
Proximal renal tubular acidosis in TASK2 K+ channel-deficient mice reveals a mechanism for stabilizing bicarbonate transport. Proc Natl Acad Sci U S A (2004) 1.40
ARF6-dependent interaction of the TWIK1 K+ channel with EFA6, a GDP/GTP exchange factor for ARF6. EMBO Rep (2004) 1.37
Task2 potassium channels set central respiratory CO2 and O2 sensitivity. Proc Natl Acad Sci U S A (2010) 1.36
Gating and modulation of presumptive NaV1.9 channels in enteric and spinal sensory neurons. Mol Cell Neurosci (2004) 1.36
Inflammatory mediators increase Nav1.9 current and excitability in nociceptors through a coincident detection mechanism. J Gen Physiol (2008) 1.34
The versatile nature of the calcium-permeable cation channel TRPP2. EMBO Rep (2006) 1.34
Selective expression of a persistent tetrodotoxin-resistant Na+ current and NaV1.9 subunit in myenteric sensory neurons. J Neurosci (2003) 1.33
Epigenetic aberrations in leukocytes of patients with schizophrenia: association of global DNA methylation with antipsychotic drug treatment and disease onset. FASEB J (2012) 1.33
Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue. Proc Natl Acad Sci U S A (2009) 1.31
AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K(+) channels into open leak channels. EMBO J (2006) 1.24
Acid-sensing ion channels in postoperative pain. J Neurosci (2011) 1.23
The del22q11.2 candidate gene Tbx1 controls regional outflow tract identity and coronary artery patterning. Circ Res (2008) 1.23
FGFR4 signaling is a necessary step in limb muscle differentiation. Development (2002) 1.23
Wnt4 is required for proper male as well as female sexual development. Dev Biol (2004) 1.23
Multiple desensitization mechanisms of mechanotransducer channels shape firing of mechanosensory neurons. J Neurosci (2010) 1.20
Adenovirus-36 is associated with obesity in children and adults in Sweden as determined by rapid ELISA. PLoS One (2012) 1.20
A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes. EMBO J (2010) 1.18
Potassium channel silencing by constitutive endocytosis and intracellular sequestration. J Biol Chem (2009) 1.17
Role of TASK2 potassium channels regarding volume regulation in primary cultures of mouse proximal tubules. J Gen Physiol (2003) 1.16
Polycystins, calcium signaling, and human diseases. Biochem Biophys Res Commun (2004) 1.14
Mtap2 is a constituent of the protein network that regulates twik-related K+ channel expression and trafficking. J Neurosci (2008) 1.12
Molecular regulations governing TREK and TRAAK channel functions. Channels (Austin) (2011) 1.11
Neurotransmitter modulation of small-conductance Ca2+-activated K+ channels by regulation of Ca2+ gating. Neuron (2008) 1.11
Examining the public refusal to consent to DNA biobanking: empirical data from a Swedish population-based study. J Med Ethics (2010) 1.11
Does sumoylation control K2P1/TWIK1 background K+ channels? Cell (2007) 1.10
Genetic and epigenetic associations of MAOA and NR3C1 with depression and childhood adversities. Int J Neuropsychopharmacol (2013) 1.09
Expression and localization of the Nav1.9 sodium channel in enteric neurons and in trigeminal sensory endings: implication for intestinal reflex function and orofacial pain. Mol Cell Neurosci (2007) 1.09
TWIK1, a unique background channel with variable ion selectivity. Proc Natl Acad Sci U S A (2012) 1.09
Persistent Nav1.6 current at axon initial segments tunes spike timing of cerebellar granule cells. J Physiol (2010) 1.06
CRY2 is associated with rapid cycling in bipolar disorder patients. PLoS One (2010) 1.05
Myocardium at the base of the aorta and pulmonary trunk is prefigured in the outflow tract of the heart and in subdomains of the second heart field. Dev Biol (2007) 1.04
TASK-2 channels contribute to pH sensitivity of retrotrapezoid nucleus chemoreceptor neurons. J Neurosci (2013) 1.03
Antidepressant treatment is associated with epigenetic alterations in the promoter of P11 in a genetic model of depression. Int J Neuropsychopharmacol (2011) 1.03
Differential targeting and functional specialization of sodium channels in cultured cerebellar granule cells. J Physiol (2005) 1.02
Nav1.9 channel contributes to mechanical and heat pain hypersensitivity induced by subacute and chronic inflammation. PLoS One (2011) 1.02
TAFA4, a chemokine-like protein, modulates injury-induced mechanical and chemical pain hypersensitivity in mice. Cell Rep (2013) 1.02
Glucose inhibition persists in hypothalamic neurons lacking tandem-pore K+ channels. J Neurosci (2009) 1.02
Hes1 is expressed in the second heart field and is required for outflow tract development. PLoS One (2009) 1.01
The Nav1.9 channel regulates colonic motility in mice. Front Neurosci (2013) 1.00
Activation of neurokinin 3 receptor increases Na(v)1.9 current in enteric neurons. J Physiol (2009) 1.00
Truncation of the Shaker-like voltage-gated potassium channel, Kv1.1, causes megencephaly. Eur J Neurosci (2003) 1.00
Ciliar functions in the nephron. Pflugers Arch (2009) 0.99
The functional Val158Met polymorphism in catechol-O-methyltransferase (COMT) is associated with depression and motivation in men from a Swedish population-based study. J Affect Disord (2010) 0.98
LTP in hippocampal neurons is associated with a CaMKII-mediated increase in GluA1 surface expression. J Neurochem (2011) 0.98
Cardiovascular polycystins: insights from autosomal dominant polycystic kidney disease and transgenic animal models. Trends Cardiovasc Med (2006) 0.98
Sensing pressure in the cardiovascular system: Gq-coupled mechanoreceptors and TRP channels. J Mol Cell Cardiol (2009) 0.98
Molecular basis of the mammalian pressure-sensitive ion channels: focus on vascular mechanotransduction. Prog Biophys Mol Biol (2008) 0.96
Hepatocyte growth factor-Met signaling is required for Runx1 extinction and peptidergic differentiation in primary nociceptive neurons. J Neurosci (2010) 0.96
MRI and in situ hybridization reveal early disturbances in brain size and gene expression in the megencephalic (mceph/mceph) mouse. Eur J Neurosci (2003) 0.95
Human ASIC3 channel dynamically adapts its activity to sense the extracellular pH in both acidic and alkaline directions. Proc Natl Acad Sci U S A (2012) 0.93
Antiepileptic popular ketogenic diet: emerging twists in an ancient story. Prog Neurobiol (2005) 0.93
A single amino acid residue constitutes the third dimerization domain essential for the assembly and function of the tetrameric polycystin-2 (TRPP2) channel. J Biol Chem (2011) 0.91
Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy. EMBO J (2012) 0.91
Venom toxins in the exploration of molecular, physiological and pathophysiological functions of acid-sensing ion channels. Toxicon (2013) 0.91
Lack of potassium channel induces proliferation and survival causing increased neurogenesis and two-fold hippocampus enlargement. Hippocampus (2007) 0.91
Serological data analyses show that adenovirus 36 infection is associated with obesity: a meta-analysis involving 5739 subjects. Obesity (Silver Spring) (2013) 0.90
NGF inhibits M/KCNQ currents and selectively alters neuronal excitability in subsets of sympathetic neurons depending on their M/KCNQ current background. J Gen Physiol (2008) 0.90
Properties of branchiomeric and somite-derived muscle development in Tbx1 mutant embryos. Dev Dyn (2008) 0.90
Membrane potential-regulated transcription of the resting K+ conductance TASK-3 via the calcineurin pathway. J Biol Chem (2006) 0.90
A novel function for cadherin-11 in the regulation of motor axon elongation and fasciculation. Mol Cell Neurosci (2005) 0.90
P2RX7: expression responds to sleep deprivation and associates with rapid cycling in bipolar disorder type 1. PLoS One (2012) 0.89
ATP signalling is crucial for the response of human keratinocytes to mechanical stimulation by hypo-osmotic shock. Exp Dermatol (2011) 0.88
Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report. PLoS One (2013) 0.88
A truncated Kv1.1 protein in the brain of the megencephaly mouse: expression and interaction. BMC Neurosci (2005) 0.88
Migrating and myelinating potential of neural precursors engineered to overexpress PSA-NCAM. Mol Cell Neurosci (2004) 0.87
Large-scale genotyping of single nucleotide polymorphisms by Pyrosequencingtrade mark and validation against the 5'nuclease (Taqman((R))) assay. Hum Mutat (2002) 0.87
Touch sense: functional organization and molecular determinants of mechanosensitive receptors. Channels (Austin) (2012) 0.87
Mechanoprotection by polycystins against apoptosis is mediated through the opening of stretch-activated K(2P) channels. Cell Rep (2012) 0.86
Pharmacological and signaling properties of endogenous P2Y1 receptors in cystic fibrosis transmembrane conductance regulator-expressing Chinese hamster ovary cells. J Pharmacol Exp Ther (2004) 0.85
CLOCK is suggested to associate with comorbid alcohol use and depressive disorders. J Circadian Rhythms (2010) 0.85
Specialized functions of Nav1.5 and Nav1.9 channels in electrogenesis of myenteric neurons in intact mouse ganglia. J Neurosci (2014) 0.85
Fetal brain hypometabolism during prolonged hypoxaemia in the llama. J Physiol (2005) 0.84
PreproNPY Pro7 protects against depression despite exposure to environmental risk factors. J Affect Disord (2009) 0.84
Involvement of voltage-gated sodium channels blockade in the analgesic effects of orphenadrine. Pain (2009) 0.84
Kv1.1 null mice have enlarged hippocampus and ventral cortex. BMC Neurosci (2007) 0.84
Recording of mechanosensitive currents using piezoelectrically driven mechanostimulator. Nat Protoc (2011) 0.84
Complementary expression and regulation of cadherins 6 and 11 during specific steps of motoneuron differentiation. Mol Cell Neurosci (2002) 0.83
Behavioral characterization of mice lacking Trek channels. Front Behav Neurosci (2012) 0.83
The thermosensitive potassium channel TREK-1 contributes to coolness-evoked responses of Grueneberg ganglion neurons. Cell Mol Neurobiol (2013) 0.82
Carbamazepine treatment recovered low N-acetylaspartate+N-acetylaspartylglutamate (tNAA) levels in the megencephaly mouse BALB/cByJ-Kv1.1(mceph/mceph). Neurobiol Dis (2006) 0.82