PubRank

Taiping Chen

Author PubWeight™ 65.58‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin. Curr Biol 2003 9.13
2 Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells. Mol Cell 2011 4.89
3 The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation. Nat Genet 2008 4.40
4 DNA methyltransferases control telomere length and telomere recombination in mammalian cells. Nat Cell Biol 2006 4.38
5 KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints. Nature 2009 2.98
6 A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases. Nat Struct Mol Biol 2008 2.43
7 Regulation and function of DNA methylation in plants and animals. Cell Res 2011 2.41
8 The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure. PLoS Genet 2008 2.35
9 Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all-iPS cell mice from terminally differentiated B cells. Nat Genet 2012 2.35
10 Synergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the methylation of Oct4 and Nanog. Mol Cell Biol 2007 2.15
11 Ring1b-mediated H2A ubiquitination associates with inactive X chromosomes and is involved in initiation of X inactivation. J Biol Chem 2004 2.15
12 Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization. J Biol Chem 2005 2.10
13 Lsh is involved in de novo methylation of DNA. EMBO J 2006 1.57
14 A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases. Nat Struct Mol Biol 2008 1.51
15 Ablation of the Sam68 RNA binding protein protects mice from age-related bone loss. PLoS Genet 2005 1.44
16 Roles for Dnmt3b in mammalian development: a mouse model for the ICF syndrome. Development 2006 1.44
17 Nuclear retention of MBP mRNAs in the quaking viable mice. Neuron 2002 1.41
18 A mouse PRMT1 null allele defines an essential role for arginine methylation in genome maintenance and cell proliferation. Mol Cell Biol 2009 1.40
19 A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells. Blood 2013 1.38
20 DOT1L regulates dystrophin expression and is critical for cardiac function. Genes Dev 2011 1.25
21 Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells. Cancer Res 2010 1.22
22 The physiological and pathophysiological role of PRMT1-mediated protein arginine methylation. Pharmacol Res 2009 1.15
23 KMT1E mediated H3K9 methylation is required for the maintenance of embryonic stem cells by repressing trophectoderm differentiation. Stem Cells 2010 1.14
24 Genetic alterations of DNA methylation machinery in human diseases. Epigenomics 2015 1.12
25 LSD1 demethylates histone and non-histone proteins. Epigenetics 2009 1.11
26 A methyl-CpG-binding protein 2-enhanced green fluorescent protein reporter mouse model provides a new tool for studying the neuronal basis of Rett syndrome. Neuroreport 2008 1.06
27 Allele-specific H3K79 Di- versus trimethylation distinguishes opposite parental alleles at imprinted regions. Mol Cell Biol 2010 1.01
28 Regulation of DNA methylation activity through Dnmt3L promoter methylation by Dnmt3 enzymes in embryonic development. Hum Mol Genet 2008 1.00
29 Overcoming erlotinib resistance with tailored treatment regimen in patient-derived xenografts from naïve Asian NSCLC patients. Int J Cancer 2012 0.96
30 Histone lysine methylation in genomic imprinting. Epigenetics 2009 0.92
31 Tet family of 5-methylcytosine dioxygenases in mammalian development. J Hum Genet 2013 0.86
32 Pharmacokinetic optimization of class-selective histone deacetylase inhibitors and identification of associated candidate predictive biomarkers of hepatocellular carcinoma tumor response. J Med Chem 2012 0.83
33 Small molecule R1498 as a well-tolerated and orally active kinase inhibitor for hepatocellular carcinoma and gastric cancer treatment via targeting angiogenesis and mitosis pathways. PLoS One 2013 0.80
34 A hypomorphic lsd1 allele results in heart development defects in mice. PLoS One 2013 0.78
35 DNA methyltransferase 1 (Dnmt1) mutation affects Snrpn imprinting in the mouse male germ line. Genome 2012 0.77
36 Retraction: Defective heart development in hypomorphic LSD1 mice. Cell Res 2012 0.75
37 Corrigendum: LSD1 is essential for oocyte meiotic progression by regulating CDC25B expression in mice. Nat Commun 2016 0.75