Published in Nat Genet on March 04, 2012
Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells. Nature (2013) 4.19
Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells. Nature (2013) 2.76
H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs. Nat Genet (2012) 2.47
Mechanisms and models of somatic cell reprogramming. Nat Rev Genet (2013) 2.09
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microRNA-29b is a novel mediator of Sox2 function in the regulation of somatic cell reprogramming. Cell Res (2012) 1.12
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A comparison of genetically matched cell lines reveals the equivalence of human iPSCs and ESCs. Nat Biotechnol (2015) 1.09
Vitamin C improves the quality of somatic cell reprogramming. Nat Genet (2012) 1.07
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Epigenetic regulation of the lncRNA MEG3 and its target c-MET in pancreatic neuroendocrine tumors. Mol Endocrinol (2015) 1.01
Using human induced pluripotent stem cells to treat retinal disease. Prog Retin Eye Res (2013) 1.00
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Chromatin features and the epigenetic regulation of pluripotency states in ESCs. Development (2014) 0.88
Antioxidant supplementation reduces genomic aberrations in human induced pluripotent stem cells. Stem Cell Reports (2014) 0.87
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Collaborative rewiring of the pluripotency network by chromatin and signalling modulating pathways. Nat Commun (2015) 0.86
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Vitamin C promotes maturation of T-cells. Antioxid Redox Signal (2013) 0.84
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Regulation of the imprinted Dlk1-Dio3 locus by allele-specific enhancer activity. Genes Dev (2016) 0.83
The epigenetic role of vitamin C in health and disease. Cell Mol Life Sci (2016) 0.83
Mechanisms for enhancing cellular reprogramming. Curr Opin Genet Dev (2014) 0.82
Staged miRNA re-regulation patterns during reprogramming. Genome Biol (2013) 0.82
Loss of non-coding RNA expression from the DLK1-DIO3 imprinted locus correlates with reduced neural differentiation potential in human embryonic stem cell lines. Stem Cell Res Ther (2015) 0.82
Somatic donor cell type correlates with embryonic, but not extra-embryonic, gene expression in postimplantation cloned embryos. PLoS One (2013) 0.81
Conversion of partially reprogrammed cells to fully pluripotent stem cells is associated with further activation of stem cell maintenance- and gamete generation-related genes. Stem Cells Dev (2014) 0.81
Switching cell fate, ncRNAs coming to play. Cell Death Dis (2013) 0.81
Human induced pluripotent stem cell derived erythroblasts can undergo definitive erythropoiesis and co-express gamma and beta globins. Br J Haematol (2014) 0.81
Building a microphysiological skin model from induced pluripotent stem cells. Stem Cell Res Ther (2013) 0.81
Human pancreatic beta-like cells converted from fibroblasts. Nat Commun (2016) 0.81
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Dppa3 expression is critical for generation of fully reprogrammed iPS cells and maintenance of Dlk1-Dio3 imprinting. Nat Commun (2015) 0.80
Ground-state conditions promote robust Prdm14 reactivation and maintain an active Dlk1-Dio3 region during reprogramming. Mol Cells (2014) 0.80
Multiple myeloma cells alter the senescence phenotype of bone marrow mesenchymal stromal cells under participation of the DLK1-DIO3 genomic region. BMC Cancer (2015) 0.80
PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells. Cell Rep (2015) 0.79
CellFateScout - a bioinformatics tool for elucidating small molecule signaling pathways that drive cells in a specific direction. Cell Commun Signal (2013) 0.79
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Cytogenetic analysis and Dlk1-Dio3 locus epigenetic status of mouse embryonic stem cells during early passages. Cytotechnology (2014) 0.78
Higher methylation in genomic DNA indicates incomplete reprogramming in induced pluripotent stem cells. Cell Reprogram (2013) 0.78
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Genomic imprinting is variably lost during reprogramming of mouse iPS cells. Stem Cell Res (2013) 0.78
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DNA methylation and hydroxymethylation in stem cells. Cell Biochem Funct (2015) 0.77
The vitamin C transporter SVCT2 is down-regulated during postnatal development of slow skeletal muscles. Histochem Cell Biol (2013) 0.76
Genome-wide gene expression analyses reveal unique cellular characteristics related to the amenability of HPC/HSCs into high-quality induced pluripotent stem cells. Stem Cell Res Ther (2016) 0.76
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Reprogramming towards totipotency is greatly facilitated by synergistic effects of small molecules. Biol Open (2017) 0.75
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Vitamin C in Stem Cell Biology: Impact on Extracellular Matrix Homeostasis and Epigenetics. Stem Cells Int (2017) 0.75
DNA repair and replication links to pluripotency and differentiation capacity of pig iPS cells. PLoS One (2017) 0.75
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Alloantigen-Induced Regulatory T Cells Generated in Presence of Vitamin C Display Enhanced Stability of Foxp3 Expression and Promote Skin Allograft Acceptance. Front Immunol (2017) 0.75
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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature (2007) 65.18
Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. Cell Stem Cell (2008) 12.45
Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency. Cell (2008) 10.68
Design and analysis of ChIP-seq experiments for DNA-binding proteins. Nat Biotechnol (2008) 10.10
Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines. Cell (2011) 8.21
Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L. Nature (2004) 7.57
Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature (2004) 7.42
Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Nature (2008) 7.07
Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells. Nature (2010) 7.05
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Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. Cell Stem Cell (2009) 5.49
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Reprogramming of mouse and human cells to pluripotency using mature microRNAs. Cell Stem Cell (2011) 4.02
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Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene. Development (2010) 1.28
Viable mice produced from three-factor induced pluripotent stem (iPS) cells through tetraploid complementation. Cell Res (2010) 0.96
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In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature (2007) 28.24
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell (2007) 21.58
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Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. Cell Stem Cell (2008) 12.45
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Network-based analysis of affected biological processes in type 2 diabetes models. PLoS Genet (2007) 2.54
Human iPSC-derived oligodendrocyte progenitor cells can myelinate and rescue a mouse model of congenital hypomyelination. Cell Stem Cell (2013) 2.51
Global regulation of X chromosomal genes by the MSL complex in Drosophila melanogaster. Genes Dev (2005) 2.46
X chromosome dosage compensation via enhanced transcriptional elongation in Drosophila. Nature (2011) 2.44
A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases. Nat Struct Mol Biol (2008) 2.43
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The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure. PLoS Genet (2008) 2.35
Regulation of pluripotency and cellular reprogramming by the ubiquitin-proteasome system. Cell Stem Cell (2012) 2.35