Published in J Gen Virol on August 01, 2003
A systems approach to prion disease. Mol Syst Biol (2009) 2.49
Identification of differentially expressed genes in scrapie-infected mouse brains by using global gene expression technology. J Virol (2004) 1.50
Gene expression alterations in brains of mice infected with three strains of scrapie. BMC Genomics (2006) 1.27
Selective processing and metabolism of disease-causing mutant prion proteins. PLoS Pathog (2009) 1.22
Scrapie protein degradation by cysteine proteases in CD11c+ dendritic cells and GT1-1 neuronal cells. J Virol (2004) 0.99
Prion protein biosynthesis and its emerging role in neurodegeneration. Trends Biochem Sci (2009) 0.97
Alternative fates of newly formed PrPSc upon prion conversion on the plasma membrane. J Cell Sci (2013) 0.93
Prion disease induced alterations in gene expression in spleen and brain prior to clinical symptoms. Adv Appl Bioinform Chem (2008) 0.83
Near-infrared fluorescence imaging of apoptotic neuronal cell death in a live animal model of prion disease. ACS Chem Neurosci (2010) 0.81
Chemically induced accumulation of GAGs delays PrP(Sc) clearance but prolongs prion disease incubation time. Cell Mol Neurobiol (2008) 0.78
Prions--not your immunologist's pathogen. PLoS Pathog (2015) 0.75
Cystatin F is a biomarker of prion pathogenesis in mice. PLoS One (2017) 0.75
Lethal recessive myelin toxicity of prion protein lacking its central domain. EMBO J (2007) 2.27
Atypical BSE in Germany--proof of transmissibility and biochemical characterization. Vet Microbiol (2006) 2.10
Conversion of the BASE prion strain into the BSE strain: the origin of BSE? PLoS Pathog (2007) 1.97
Quantitative analysis of the binding affinity of poly(ADP-ribose) to specific binding proteins as a function of chain length. Nucleic Acids Res (2007) 1.73
Scrapie Agent (Strain 263K) can transmit disease via the oral route after persistence in soil over years. PLoS One (2007) 1.72
Highly bovine spongiform encephalopathy-sensitive transgenic mice confirm the essential restriction of infectivity to the nervous system in clinically diseased cattle. J Infect Dis (2005) 1.70
Epizootic emergence of Usutu virus in wild and captive birds in Germany. PLoS One (2012) 1.55
Isolation of usutu virus in Germany. Am J Trop Med Hyg (2011) 1.55
State-of-the-art review of goat TSE in the European Union, with special emphasis on PRNP genetics and epidemiology. Vet Res (2009) 1.46
Diagnosis of the first cases of scrapie in Poland. Vet J (2009) 1.44
Analysis of sequence variability of the bovine prion protein gene (PRNP) in German cattle breeds. Neurogenetics (2004) 1.43
Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction. Cardiovasc Res (2008) 1.43
Atypical scrapie prions from sheep and lack of disease in transgenic mice overexpressing human prion protein. Emerg Infect Dis (2013) 1.38
Epidemiological and genetical differences between classical and atypical scrapie cases. Vet Res (2006) 1.38
Multiple amino acid residues within the rabbit prion protein inhibit formation of its abnormal isoform. J Virol (2003) 1.35
European surveillance for West Nile virus in mosquito populations. Int J Environ Res Public Health (2013) 1.31
Prions spread via the autonomic nervous system from the gut to the central nervous system in cattle incubating bovine spongiform encephalopathy. J Gen Virol (2007) 1.30
Neuronal accumulation of abnormal prion protein in sheep carrying a scrapie-resistant genotype (PrPARR/ARR). J Gen Virol (2004) 1.27
Poly(ADP-ribosyl)ation accelerates DNA repair in a pathway dependent on Cockayne syndrome B protein. Nucleic Acids Res (2003) 1.26
Seroprevalence study in forestry workers from eastern Germany using novel genotype 3- and rat hepatitis E virus-specific immunoglobulin G ELISAs. Med Microbiol Immunol (2011) 1.22
Ionomycin-activated calpain triggers apoptosis. A probable role for Bcl-2 family members. J Biol Chem (2002) 1.15
Upregulation of miR-24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8(+) T cells sensitizing them to apoptotic cell death. Aging Cell (2012) 1.15
Immunolocalisation of PrPSc in scrapie-infected N2a mouse neuroblastoma cells by light and electron microscopy. Eur J Cell Biol (2008) 1.14
Poly(ADP-ribosyl)ation in mammalian ageing. Nucleic Acids Res (2007) 1.13
PRNP promoter polymorphisms are associated with BSE susceptibility in Swiss and German cattle. BMC Genet (2007) 1.13
Very low concentrations of arsenite suppress poly(ADP-ribosyl)ation in mammalian cells. Int J Cancer (2003) 1.11
Culicoides biting midges, arboviruses and public health in Europe. Antiviral Res (2013) 1.11
Polyclonal anti-PrP auto-antibodies induced with dimeric PrP interfere efficiently with PrPSc propagation in prion-infected cells. J Biol Chem (2003) 1.10
Poly(ADP-ribosyl)ation inhibitors: promising drug candidates for a wide variety of pathophysiologic conditions. Int J Cancer (2004) 1.10
Loss of Drop1 expression already at early tumor stages in a wide range of human carcinomas. Int J Cancer (2008) 1.08
Rat hepatitis E virus: geographical clustering within Germany and serological detection in wild Norway rats (Rattus norvegicus). Infect Genet Evol (2012) 1.08
All clinically-relevant blood components transmit prion disease following a single blood transfusion: a sheep model of vCJD. PLoS One (2011) 1.08
Increase in de novo HBV DNA integrations in response to oxidative DNA damage or inhibition of poly(ADP-ribosyl)ation. Hepatology (2002) 1.07
Rapid regulation of telomere length is mediated by poly(ADP-ribose) polymerase-1. Nucleic Acids Res (2008) 1.06
Broad geographical distribution and high genetic diversity of shrew-borne Seewis hantavirus in Central Europe. Virus Genes (2012) 1.03
The impact of Crimean-Congo hemorrhagic fever virus on public health. Antiviral Res (2013) 1.02
Tula virus infections in the Eurasian water vole in Central Europe. Vector Borne Zoonotic Dis (2012) 1.02
How to kill tumor cells with inhibitors of poly(ADP-ribosyl)ation. Int J Cancer (2010) 1.02
A modified and automated version of the 'Fluorimetric Detection of Alkaline DNA Unwinding' method to quantify formation and repair of DNA strand breaks. BMC Biotechnol (2009) 1.01
Immunological characterization of abnormal prion protein from atypical scrapie cases in sheep using a panel of monoclonal antibodies. J Gen Virol (2006) 1.01
Age and gender effects on DNA strand break repair in peripheral blood mononuclear cells. Aging Cell (2012) 1.00
Association of mitochondrial antioxidant enzymes with mitochondrial DNA as integral nucleoid constituents. FASEB J (2009) 1.00
Two new real-time quantitative reverse transcription polymerase chain reaction assays with unique target sites for the specific and sensitive detection of lineages 1 and 2 West Nile virus strains. J Vet Diagn Invest (2010) 1.00
Neuroprotection by minocycline caused by direct and specific scavenging of peroxynitrite. J Biol Chem (2010) 0.99
Detection of shrew-borne hantavirus in Eurasian pygmy shrew (Sorex minutus) in Central Europe. Infect Genet Evol (2013) 0.99
Molecular identification of small mammal species using novel cytochrome B gene-derived degenerated primers. Biochem Genet (2011) 0.98
Poly(ADP-ribosyl)ation during chromatin remodeling steps in rat spermiogenesis. Chromosoma (2005) 0.97
West Nile virus monitoring of migratory and resident birds in Germany. Vector Borne Zoonotic Dis (2010) 0.97
Seroprevalence study in forestry workers of a non-endemic region in eastern Germany reveals infections by Tula and Dobrava-Belgrade hantaviruses. Med Microbiol Immunol (2011) 0.97
Spread of classic BSE prions from the gut via the peripheral nervous system to the brain. Am J Pathol (2012) 0.96
Use of murine bioassay to resolve ovine transmissible spongiform encephalopathy cases showing a bovine spongiform encephalopathy molecular profile. Brain Pathol (2011) 0.95
Degradation of scrapie associated prion protein (PrPSc) by the gastrointestinal microbiota of cattle. Vet Res (2006) 0.95
Characterization of atypical scrapie cases from Great Britain in transgenic ovine PrP mice. J Gen Virol (2010) 0.95
Amino acid sequence and prion strain specific effects on the in vitro and in vivo convertibility of ovine/murine and bovine/murine prion protein chimeras. Biochim Biophys Acta (2006) 0.95
BSE infectivity in the absence of detectable PrP(Sc) accumulation in the tongue and nasal mucosa of terminally diseased cattle. J Gen Virol (2010) 0.95
Pathogenesis of West Nile virus lineage 1 and 2 in experimentally infected large falcons. Vet Microbiol (2012) 0.94
Subcellular localization and in vivo subunit interactions of ubiquitous mu-calpain. J Biol Chem (2003) 0.93
Imidazoquinolinone, imidazopyridine, and isoquinolindione derivatives as novel and potent inhibitors of the poly(ADP-ribose) polymerase (PARP): a comparison with standard PARP inhibitors. Mol Pharmacol (2008) 0.93
Seroepidemiological study in a Puumala virus outbreak area in South-East Germany. Med Microbiol Immunol (2009) 0.93
Glycan-controlled epitopes of prion protein include a major determinant of susceptibility to sheep scrapie. J Virol (2004) 0.92
Functional relevance of DNA polymorphisms within the promoter region of the prion protein gene and their association to BSE infection. FASEB J (2007) 0.92
Dobrava-belgrade virus spillover infections, Germany. Emerg Infect Dis (2009) 0.90
High-affinity interaction of poly(ADP-ribose) and the human DEK oncoprotein depends upon chain length. Biochemistry (2010) 0.90
Poly(ADP-ribose) polymerase-1 is a survival factor for radiation-exposed intestinal epithelial stem cells in vivo. Nucleic Acids Res (2003) 0.90
Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1. Mech Ageing Dev (2010) 0.90
Pleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammation. Oxid Med Cell Longev (2012) 0.90
Effect of zinc on cellular poly(ADP-ribosyl)ation capacity. Exp Gerontol (2007) 0.89
Rapid testing leads to the underestimation of the scrapie prevalence in an affected sheep and goat flock. Vet Microbiol (2007) 0.89
Cystatins in non-small cell lung cancer: tissue levels, localization and relation to prognosis. Oncol Rep (2006) 0.89
Poly(ADP-ribose) glycohydrolase as a target for neuroprotective intervention: assessment of currently available pharmacological tools. Eur J Pharmacol (2004) 0.88
The automated FADU-assay, a potential high-throughput in vitro method for early screening of DNA breakage. ALTEX (2011) 0.88
Phylogenetic analysis of Puumala virus subtype Bavaria, characterization and diagnostic use of its recombinant nucleocapsid protein. Virus Genes (2011) 0.88
Regional and phenotype heterogeneity of cellular prion proteins in the human brain. Eur J Neurosci (2007) 0.88
Chromatin composition is changed by poly(ADP-ribosyl)ation during chromatin immunoprecipitation. PLoS One (2012) 0.87
Effects of polymorphisms in ovine and caprine prion protein alleles on cell-free conversion. Vet Res (2011) 0.87
From high-throughput cell culture screening to mouse model: identification of new inhibitor classes against prion disease. ChemMedChem (2011) 0.87
Hepatitis E virus seroprevalence of domestic pigs in Germany determined by a novel in-house and two reference ELISAs. J Virol Methods (2013) 0.86
The novel sorting nexin SNX33 interferes with cellular PrP formation by modulation of PrP shedding. Traffic (2008) 0.86
Poly(ADP-ribose) polymerase (PARP-1) and p53 independently function in regulating double-strand break repair in primate cells. Nucleic Acids Res (2004) 0.86
Biochemical Characteristics and PrP(Sc) Distribution Pattern in the Brains of Cattle Experimentally Challenged with H-type and L-type Atypical BSE. PLoS One (2013) 0.86
Use of competition ELISA for monitoring of West Nile virus infections in horses in Germany. Int J Environ Res Public Health (2013) 0.86
Reduced poly(ADP-ribosyl)ation in lymphocytes of laryngeal cancer patients: results of a case-control study. Int J Cancer (2002) 0.86
Quantification of cellular poly(ADP-ribosyl)ation by stable isotope dilution mass spectrometry reveals tissue- and drug-dependent stress response dynamics. ACS Chem Biol (2013) 0.85
Biochemical and immunohistochemical characterization of feline spongiform encephalopathy in a German captive cheetah. J Gen Virol (2010) 0.85
Site-specific noncovalent interaction of the biopolymer poly(ADP-ribose) with the Werner syndrome protein regulates protein functions. ACS Chem Biol (2012) 0.85
Role of poly(ADP-ribose) polymerase in sulfur mustard toxicity. Toxicology (2008) 0.85
DNA damage in Nijmegen Breakage Syndrome cells leads to PARP hyperactivation and increased oxidative stress. PLoS Genet (2012) 0.85
Scrapie infection of prion protein-deficient cell line upon ectopic expression of mutant prion proteins. J Biol Chem (2007) 0.85
West Nile virus monitoring in migrating and resident water birds in Iran: are common coots the main reservoirs of the virus in wetlands? Vector Borne Zoonotic Dis (2011) 0.85
Cellular prion protein acquires resistance to proteolytic degradation following copper ion binding. Biol Chem (2004) 0.85
BSE infectivity in jejunum, ileum and ileocaecal junction of incubating cattle. Vet Res (2011) 0.84
Effects of psychotherapy on DNA strand break accumulation originating from traumatic stress. Psychother Psychosom (2014) 0.84
Ex vivo supplementation with nicotinic acid enhances cellular poly(ADP-ribosyl)ation and improves cell viability in human peripheral blood mononuclear cells. Biochem Pharmacol (2010) 0.84
Inhibition of prion amplification by expression of dominant inhibitory mutants--a systematic insertion mutagenesis study. Infect Disord Drug Targets (2009) 0.84
Enzyme characteristics of recombinant poly(ADP-ribose) polymerases-1 of rat and human origin mirror the correlation between cellular poly(ADP-ribosyl)ation capacity and species-specific life span. Mech Ageing Dev (2010) 0.84
Physiological role of the cellular prion protein (PrPc): protein profiling study in two cell culture systems. J Proteome Res (2008) 0.84
Poly(ADP-ribose)-mediated interplay of XPA and PARP1 leads to reciprocal regulation of protein function. FEBS J (2014) 0.84
Multiple infections of rodents with zoonotic pathogens in Austria. Vector Borne Zoonotic Dis (2014) 0.83
Sentinel birds in wild-bird resting sites as potential indicators for West Nile virus infections in Germany. Arch Virol (2010) 0.83
EU-approved rapid tests for bovine spongiform encephalopathy detect atypical forms: a study for their sensitivities. PLoS One (2012) 0.83