Published in Int J Cancer on November 12, 2010
Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells. Clin Epigenetics (2011) 1.31
Complex DNA repair pathways as possible therapeutic targets to overcome temozolomide resistance in glioblastoma. Front Oncol (2012) 1.14
Digital transcriptome profiling of normal and glioblastoma-derived neural stem cells identifies genes associated with patient survival. Genome Med (2012) 1.11
Synthetic lethal targeting of DNA double-strand break repair deficient cells by human apurinic/apyrimidinic endonuclease inhibitors. Int J Cancer (2012) 1.04
Poly(ADP-ribose) polymerase-1 is a key mediator of cisplatin-induced kidney inflammation and injury. Free Radic Biol Med (2011) 1.03
Alternative modes of binding of poly(ADP-ribose) polymerase 1 to free DNA and nucleosomes. J Biol Chem (2012) 0.97
PARP-1 regulates resistance of pancreatic cancer to TRAIL therapy. Clin Cancer Res (2013) 0.93
The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedin. Oncotarget (2015) 0.89
Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to Cisplatin and poly (adp-ribose) polymerase inhibition. PLoS One (2012) 0.89
Optimizing molecular-targeted therapies in ovarian cancer: the renewed surge of interest in ovarian cancer biomarkers and cell signaling pathways. J Oncol (2012) 0.88
Site-specific noncovalent interaction of the biopolymer poly(ADP-ribose) with the Werner syndrome protein regulates protein functions. ACS Chem Biol (2012) 0.85
Fish oil suppresses cell growth and metastatic potential by regulating PTEN and NF-κB signaling in colorectal cancer. PLoS One (2014) 0.81
Effects of poly (ADP-ribosyl) polymerase (PARP) inhibitor on cisplatin resistance & proliferation of the ovarian cancer C13* cells. Indian J Med Res (2013) 0.79
Single cell resolution in vivo imaging of DNA damage following PARP inhibition. Sci Rep (2015) 0.79
Special Agents Hunting Down Women Silent Killer: The Emerging Role of the p38α Kinase. J Oncol (2012) 0.78
Potential application of curcumin and its analogues in the treatment strategy of patients with primary epithelial ovarian cancer. Int J Mol Sci (2014) 0.78
NELL2 function in the protection of cells against endoplasmic reticulum stress. Mol Cells (2014) 0.77
The Sound of Silence: RNAi in Poly (ADP-Ribose) Research. Genes (Basel) (2012) 0.76
Exclusive destruction of mitotic spindles in human cancer cells. Oncotarget (2017) 0.75
Discovery and structure-activity relationship of novel 2,3-dihydrobenzofuran-7-carboxamide and 2,3-dihydrobenzofuran-3(2H)-one-7-carboxamide derivatives as poly(ADP-ribose)polymerase-1 inhibitors. J Med Chem (2014) 0.75
Lethal recessive myelin toxicity of prion protein lacking its central domain. EMBO J (2007) 2.27
Quantitative analysis of the binding affinity of poly(ADP-ribose) to specific binding proteins as a function of chain length. Nucleic Acids Res (2007) 1.73
Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction. Cardiovasc Res (2008) 1.43
Poly(ADP-ribosyl)ation accelerates DNA repair in a pathway dependent on Cockayne syndrome B protein. Nucleic Acids Res (2003) 1.26
Upregulation of miR-24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8(+) T cells sensitizing them to apoptotic cell death. Aging Cell (2012) 1.15
Immunolocalisation of PrPSc in scrapie-infected N2a mouse neuroblastoma cells by light and electron microscopy. Eur J Cell Biol (2008) 1.14
Poly(ADP-ribosyl)ation in mammalian ageing. Nucleic Acids Res (2007) 1.13
Very low concentrations of arsenite suppress poly(ADP-ribosyl)ation in mammalian cells. Int J Cancer (2003) 1.11
Poly(ADP-ribosyl)ation inhibitors: promising drug candidates for a wide variety of pathophysiologic conditions. Int J Cancer (2004) 1.10
Increase in de novo HBV DNA integrations in response to oxidative DNA damage or inhibition of poly(ADP-ribosyl)ation. Hepatology (2002) 1.07
Rapid regulation of telomere length is mediated by poly(ADP-ribose) polymerase-1. Nucleic Acids Res (2008) 1.06
A modified and automated version of the 'Fluorimetric Detection of Alkaline DNA Unwinding' method to quantify formation and repair of DNA strand breaks. BMC Biotechnol (2009) 1.01
Age and gender effects on DNA strand break repair in peripheral blood mononuclear cells. Aging Cell (2012) 1.00
Association of mitochondrial antioxidant enzymes with mitochondrial DNA as integral nucleoid constituents. FASEB J (2009) 1.00
Neuroprotection by minocycline caused by direct and specific scavenging of peroxynitrite. J Biol Chem (2010) 0.99
Poly(ADP-ribosyl)ation during chromatin remodeling steps in rat spermiogenesis. Chromosoma (2005) 0.97
Up-regulation of cathepsin B and cathepsin L activities in scrapie-infected mouse Neuro2a cells. J Gen Virol (2003) 0.95
Imidazoquinolinone, imidazopyridine, and isoquinolindione derivatives as novel and potent inhibitors of the poly(ADP-ribose) polymerase (PARP): a comparison with standard PARP inhibitors. Mol Pharmacol (2008) 0.93
Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1. Mech Ageing Dev (2010) 0.90
High-affinity interaction of poly(ADP-ribose) and the human DEK oncoprotein depends upon chain length. Biochemistry (2010) 0.90
Pleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammation. Oxid Med Cell Longev (2012) 0.90
Poly(ADP-ribose) polymerase-1 is a survival factor for radiation-exposed intestinal epithelial stem cells in vivo. Nucleic Acids Res (2003) 0.90
Effect of zinc on cellular poly(ADP-ribosyl)ation capacity. Exp Gerontol (2007) 0.89
Poly(ADP-ribose) glycohydrolase as a target for neuroprotective intervention: assessment of currently available pharmacological tools. Eur J Pharmacol (2004) 0.88
The automated FADU-assay, a potential high-throughput in vitro method for early screening of DNA breakage. ALTEX (2011) 0.88
Chromatin composition is changed by poly(ADP-ribosyl)ation during chromatin immunoprecipitation. PLoS One (2012) 0.87
Poly(ADP-ribose) polymerase (PARP-1) and p53 independently function in regulating double-strand break repair in primate cells. Nucleic Acids Res (2004) 0.86
Reduced poly(ADP-ribosyl)ation in lymphocytes of laryngeal cancer patients: results of a case-control study. Int J Cancer (2002) 0.86
Site-specific noncovalent interaction of the biopolymer poly(ADP-ribose) with the Werner syndrome protein regulates protein functions. ACS Chem Biol (2012) 0.85
Quantification of cellular poly(ADP-ribosyl)ation by stable isotope dilution mass spectrometry reveals tissue- and drug-dependent stress response dynamics. ACS Chem Biol (2013) 0.85
DNA damage in Nijmegen Breakage Syndrome cells leads to PARP hyperactivation and increased oxidative stress. PLoS Genet (2012) 0.85
Role of poly(ADP-ribose) polymerase in sulfur mustard toxicity. Toxicology (2008) 0.85
Enzyme characteristics of recombinant poly(ADP-ribose) polymerases-1 of rat and human origin mirror the correlation between cellular poly(ADP-ribosyl)ation capacity and species-specific life span. Mech Ageing Dev (2010) 0.84
Poly(ADP-ribose)-mediated interplay of XPA and PARP1 leads to reciprocal regulation of protein function. FEBS J (2014) 0.84
Effects of psychotherapy on DNA strand break accumulation originating from traumatic stress. Psychother Psychosom (2014) 0.84
Ex vivo supplementation with nicotinic acid enhances cellular poly(ADP-ribosyl)ation and improves cell viability in human peripheral blood mononuclear cells. Biochem Pharmacol (2010) 0.84
Aging of different avian cultured cells: lack of ROS-induced damage and quality control mechanisms. Mech Ageing Dev (2009) 0.83
Quantitative analysis of WRN exonuclease activity by isotope dilution mass spectrometry. Mech Ageing Dev (2012) 0.83
High-throughput analysis of DNA interstrand crosslinks in human peripheral blood mononuclear cells by automated reverse FADU assay. Toxicology (2010) 0.82
Poly(ADP-RIBOSE) polymerase-1 (Parp-1) antagonizes topoisomerase I-dependent recombination stimulation by P53. Nucleic Acids Res (2006) 0.82
Prion protein in milk. PLoS One (2006) 0.82
Mechanisms of Hg species induced toxicity in cultured human astrocytes: genotoxicity and DNA-damage response. Metallomics (2014) 0.82
Poly(ADP-ribosyl)ation, PARP, and aging. Sci Aging Knowledge Environ (2004) 0.82
Induction of DNA strand breaks by dental composite components compared to X-ray exposure in human gingival fibroblasts. Arch Toxicol (2010) 0.81
Genetic heterogeneity versus molecular analysis of prion susceptibility in neuroblasma N2a sublines. Arch Virol (2008) 0.80
Oxytocin modulates proliferation and stress responses of human skin cells: implications for atopic dermatitis. Exp Dermatol (2013) 0.80
Highly selective apoptotic cell death induced by halo-salane titanium complexes. ChemMedChem (2009) 0.79
Induction of poly(ADP-ribosyl)ation and DNA damage in human peripheral lymphocytes after treatment with (-)-epigallocatechin-gallate. Mutat Res (2003) 0.79
Microdeletions within the hydrophobic core region of cellular prion protein alter its topology and metabolism. Biochem Biophys Res Commun (2010) 0.79
Zinc and ageing (ZINCAGE Project). Exp Gerontol (2008) 0.78
The deletion of amino acids 114-121 in the TM1 domain of mouse prion protein stabilizes its conformation but does not affect the overall structure. Biochim Biophys Acta (2007) 0.78
The octarepeat region of prion protein, but not the TM1 domain, is important for the antioxidant effect of prion protein. Free Radic Biol Med (2008) 0.78
High-resolution quantitative metabolome analysis of urine by automated flow injection NMR. Anal Chem (2013) 0.78
Neuroprotective therapies for Alzheimer's disease. Curr Pharm Des (2006) 0.78
A caveat in mouse genetic engineering: ectopic gene targeting in ES cells by bidirectional extension of the homology arms of a gene replacement vector carrying human PARP-1. Transgenic Res (2008) 0.77
Molecular mechanisms of Mn induced neurotoxicity: RONS generation, genotoxicity, and DNA-damage response. Mol Nutr Food Res (2013) 0.77
Rapamycin inhibits poly(ADP-ribosyl)ation in intact cells. Biochem Biophys Res Commun (2009) 0.76
Genetic and environmental influence on DNA strand break repair: a twin study. Environ Mol Mutagen (2013) 0.76
Cell cycle-dependent cytotoxicity and mitotic spindle checkpoint dependency of investigational and approved antimitotic agents. Int J Cancer (2011) 0.76
An automated Fpg-based FADU method for the detection of oxidative DNA lesions and screening of antioxidants. Toxicology (2013) 0.75
Meeting report: 4th European Congress of Biogerontology. Sci Aging Knowledge Environ (2005) 0.75
The first Sino-German Symposium on DNA Repair and Human Diseases. DNA Repair (Amst) (2011) 0.75
In-situ analysis of cellular poly(ADP-ribose) production in scrapie-infected mouse neuroblastoma cells. Histochem J (2003) 0.75
SENS and the polarization of aging-related research. Sci Aging Knowledge Environ (2006) 0.75
Stress Hormone-Mediated DNA Damage Response -- Implications for Cellular Senescence and Tumour Progression. Curr Drug Targets (2016) 0.75