Published in Lung Cancer on August 01, 2003
Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged. Genes Dev (2010) 4.75
Heterogeneous nuclear ribonucleoprotein K is over expressed, aberrantly localised and is associated with poor prognosis in colorectal cancer. Br J Cancer (2006) 1.65
Concentration-dependent control of pyruvate kinase M mutually exclusive splicing by hnRNP proteins. Nat Struct Mol Biol (2012) 1.22
hnRNP A1: the Swiss army knife of gene expression. Int J Mol Sci (2013) 1.19
Abnormalities in nitric oxide and its derivatives in lung cancer. Am J Respir Crit Care Med (2005) 1.07
Deregulated expression of hnRNP A/B proteins in human non-small cell lung cancer: parallel assessment of protein and mRNA levels in paired tumour/non-tumour tissues. BMC Cancer (2010) 1.05
Response of heterogeneous ribonuclear proteins (hnRNP) to ionising radiation and their involvement in DNA damage repair. Int J Radiat Biol (2009) 1.05
Heterogeneous nuclear ribonucleoprotein K represses the production of pro-apoptotic Bcl-xS splice isoform. J Biol Chem (2009) 1.04
Increased expression of the heterogeneous nuclear ribonucleoprotein K in pancreatic cancer and its association with the mutant p53. Int J Cancer (2010) 1.04
Heterogeneous nuclear ribonucleoprotein K: altered pattern of expression associated with diagnosis and prognosis of prostate cancer. Br J Cancer (2009) 0.96
Higher expression of the heterogeneous nuclear ribonucleoprotein k in melanoma. Ann Surg Oncol (2010) 0.91
Development of a novel splice array platform and its application in the identification of alternative splice variants in lung cancer. BMC Genomics (2010) 0.91
Role of nitric oxide and its metabolites as potential markers in lung cancer. Ann Thorac Med (2010) 0.90
Comprehensive analysis of the palindromic motif TCTCGCGAGA: a regulatory element of the HNRNPK promoter. DNA Res (2010) 0.90
Identification of novel deregulated RNA metabolism-related genes in non-small cell lung cancer. PLoS One (2012) 0.88
In vivo identification of ribonucleoprotein-RNA interactions. Proc Natl Acad Sci U S A (2006) 0.87
HnRNP A1/A2 and SF2/ASF regulate alternative splicing of interferon regulatory factor-3 and affect immunomodulatory functions in human non-small cell lung cancer cells. PLoS One (2013) 0.87
Proteome analysis of human gastric cardia adenocarcinoma by laser capture microdissection. BMC Cancer (2007) 0.86
Post-transcriptional regulation by poly(ADP-ribosyl)ation of the RNA-binding proteins. Int J Mol Sci (2013) 0.85
PSMB8 and PBK as potential gastric cancer subtype-specific biomarkers associated with prognosis. Oncotarget (2016) 0.81
Chemical proteomics identifies heterogeneous nuclear ribonucleoprotein (hnRNP) A1 as the molecular target of quercetin in its anti-cancer effects in PC-3 cells. J Biol Chem (2014) 0.80
Heterogeneous nuclear ribonucleoproteins A1 and A2 modulate expression of Tid1 isoforms and EGFR signaling in non-small cell lung cancer. Oncotarget (2016) 0.79
A truncated hnRNP A1 isoform, lacking the RGG-box RNA binding domain, can efficiently regulate HIV-1 splicing and replication. Biochim Biophys Acta (2014) 0.77
Global identification of hnRNP A1 binding sites for SSO-based splicing modulation. BMC Biol (2016) 0.77
The role of splicing factors in deregulation of alternative splicing during oncogenesis and tumor progression. Mol Cell Oncol (2014) 0.75
hnRNPK inhibits GSK3β Ser9 phosphorylation, thereby stabilizing c-FLIP and contributes to TRAIL resistance in H1299 lung adenocarcinoma cells. Sci Rep (2016) 0.75
Cytoplasmic Accumulation of Heterogeneous Nuclear Ribonucleoprotein K Strongly Promotes Tumor Invasion in Renal Cell Carcinoma Cells. PLoS One (2015) 0.75
Effects of rs3846662 Variants on HMGCR mRNA and Protein Levels and on Markers of Alzheimer's Disease Pathology. J Mol Neurosci (2015) 0.75
Ethanol and Cancer Induce Similar Changes on Protein Expression Pattern of Human Fibroblast Cell. Iran J Pharm Res (2016) 0.75
A microRNA DNA methylation signature for human cancer metastasis. Proc Natl Acad Sci U S A (2008) 7.14
Frequent BRG1/SMARCA4-inactivating mutations in human lung cancer cell lines. Hum Mutat (2008) 3.02
Clinical benefit associated with idiotypic vaccination in patients with follicular lymphoma. J Natl Cancer Inst (2006) 2.69
Alternative splicing: an emerging topic in molecular and clinical oncology. Lancet Oncol (2007) 2.46
Assessing the relationship between lung cancer risk and emphysema detected on low-dose CT of the chest. Chest (2007) 2.43
Down-regulation of hsa-miR-10a in chronic myeloid leukemia CD34+ cells increases USF2-mediated cell growth. Mol Cancer Res (2008) 1.94
A multidrug resistance 3 gene mutation causing cholelithiasis, cholestasis of pregnancy, and adulthood biliary cirrhosis. Gastroenterology (2003) 1.90
MAX inactivation in small cell lung cancer disrupts MYC-SWI/SNF programs and is synthetic lethal with BRG1. Cancer Discov (2013) 1.85
Genetic and epigenetic modifications of Sox2 contribute to the invasive phenotype of malignant gliomas. PLoS One (2011) 1.57
Improving selection criteria for lung cancer screening. The potential role of emphysema. Am J Respir Crit Care Med (2015) 1.55
SPACE: an algorithm to predict and quantify alternatively spliced isoforms using microarrays. Genome Biol (2008) 1.52
Novel and natural knockout lung cancer cell lines for the LKB1/STK11 tumor suppressor gene. Oncogene (2004) 1.49
A prognostic DNA methylation signature for stage I non-small-cell lung cancer. J Clin Oncol (2013) 1.47
Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2. Genome Biol (2013) 1.47
Gene expression profile of omental adipose tissue in human obesity. FASEB J (2003) 1.42
A small noncoding RNA signature found in exosomes of GBM patient serum as a diagnostic tool. Neuro Oncol (2014) 1.40
[Early detection of lung cancer: the right time]. Med Clin (Barc) (2002) 1.39
Inhibition of collagen receptor discoidin domain receptor-1 (DDR1) reduces cell survival, homing, and colonization in lung cancer bone metastasis. Clin Cancer Res (2012) 1.39
[Association between microsatellite instability and clinico-pathological characteristics in sporadic colon cancer]. Med Clin (Barc) (2005) 1.38
Relative amounts of antagonistic splicing factors, hnRNP A1 and ASF/SF2, change during neoplastic lung growth: implications for pre-mRNA processing. Mol Carcinog (2004) 1.32
Anaphylatoxin C5a creates a favorable microenvironment for lung cancer progression. J Immunol (2012) 1.30
Pigment epithelium-derived factor in the monkey retinal pigment epithelium and interphotoreceptor matrix: apical secretion and distribution. Exp Eye Res (2004) 1.29
The effects of adrenomedullin overexpression in breast tumor cells. J Natl Cancer Inst (2002) 1.26
Mitogen-activated protein kinase phosphatase-1 is overexpressed in non-small cell lung cancer and is an independent predictor of outcome in patients. Clin Cancer Res (2004) 1.24
Early lung cancer detection using spiral computed tomography and positron emission tomography. Am J Respir Crit Care Med (2005) 1.22
Human follicular lymphoma cells contain oligomannose glycans in the antigen-binding site of the B-cell receptor. J Biol Chem (2006) 1.19
Cdc42 is highly expressed in colorectal adenocarcinoma and downregulates ID4 through an epigenetic mechanism. Int J Oncol (2008) 1.19
Expression of complement factor H by lung cancer cells: effects on the activation of the alternative pathway of complement. Cancer Res (2004) 1.19
Twist1 suppresses senescence programs and thereby accelerates and maintains mutant Kras-induced lung tumorigenesis. PLoS Genet (2012) 1.15
Molecular analysis of a multistep lung cancer model induced by chronic inflammation reveals epigenetic regulation of p16 and activation of the DNA damage response pathway. Neoplasia (2007) 1.12
Alternative splicing in lung cancer. J Thorac Oncol (2009) 1.12
Down-regulation of human complement factor H sensitizes non-small cell lung cancer cells to complement attack and reduces in vivo tumor growth. J Immunol (2007) 1.11
TGFBI expression is associated with a better response to chemotherapy in NSCLC. Mol Cancer (2010) 1.11
Deregulation of miR-200b, miR-200c and miR-429 indicates its potential relevant role in patients with colorectal cancer liver metastasis. J Surg Oncol (2014) 1.10
Clinical significance of miR-126 in colorectal cancer. Genes Chromosomes Cancer (2014) 1.09
A gene-alteration profile of human lung cancer cell lines. Hum Mutat (2009) 1.09
Telomeres and telomerase in lung cancer. J Thorac Oncol (2008) 1.06
Expression of tumor-derived vascular endothelial growth factor and its receptors is associated with outcome in early squamous cell carcinoma of the lung. J Clin Oncol (2012) 1.06
TWIST1 overexpression is associated with nodal invasion and male sex in primary colorectal cancer. Ann Surg Oncol (2008) 1.06
Epidermal growth factor receptor (EGFR) polymorphisms and survival in head and neck cancer patients. Oral Oncol (2006) 1.05
Receptor of activated protein C promotes metastasis and correlates with clinical outcome in lung adenocarcinoma. Am J Respir Crit Care Med (2012) 1.04
Complement activation mediates cetuximab inhibition of non-small cell lung cancer tumor growth in vivo. Mol Cancer (2010) 1.04
Choline kinase as a link connecting phospholipid metabolism and cell cycle regulation: implications in cancer therapy. Int J Biochem Cell Biol (2008) 1.04
Comparative study of four different spherical embolic particles in an animal model: a morphologic and histologic evaluation. J Vasc Interv Radiol (2008) 1.01
PP2A inhibition is a common event in colorectal cancer and its restoration using FTY720 shows promising therapeutic potential. Mol Cancer Ther (2014) 1.00
Evaluation of micro-CT for emphysema assessment in mice: comparison with non-radiological techniques. Eur Radiol (2010) 0.99
TRAP1 regulates proliferation, mitochondrial function, and has prognostic significance in NSCLC. Mol Cancer Res (2014) 0.99
A novel missense mutation in the CYLD gene in a Spanish family with multiple familial trichoepithelioma. Arch Dermatol (2007) 0.99
MEK1/2 inhibition elicits regression of autochthonous lung tumors induced by KRASG12D or BRAFV600E. Cancer Res (2012) 0.97
Polymorphisms in the thymidylate synthase and dihydropyrimidine dehydrogenase genes predict response and toxicity to capecitabine-raltitrexed in colorectal cancer. Oncol Rep (2007) 0.96
Toxic epidermal necrolysis related to pemetrexed and carboplatin with vitamin B12 and folic acid supplementation for advanced non-small cell lung cancer. Onkologie (2009) 0.96
Proteomic analysis of chemonaive pediatric osteosarcomas and corresponding normal bone reveals multiple altered molecular targets. J Proteome Res (2009) 0.96
Biological profile of new apoptotic agents based on 2,4-pyrido[2,3-d]pyrimidine derivatives. Bioorg Med Chem (2006) 0.96
Long-term results after resection for bone sarcoma pulmonary metastases. Eur J Cardiothorac Surg (2009) 0.95
Inhibitor of differentiation-1 as a novel prognostic factor in NSCLC patients with adenocarcinoma histology and its potential contribution to therapy resistance. Clin Cancer Res (2011) 0.95
Differential expression of Rac1 identifies its target genes and its contribution to progression of colorectal cancer. Int J Biochem Cell Biol (2007) 0.95
Identification of importin 8 (IPO8) as the most accurate reference gene for the clinicopathological analysis of lung specimens. BMC Mol Biol (2008) 0.95
The oncoprotein SF2/ASF promotes non-small cell lung cancer survival by enhancing survivin expression. Clin Cancer Res (2010) 0.95
Altered expression of adhesion molecules and epithelial-mesenchymal transition in silica-induced rat lung carcinogenesis. Lab Invest (2004) 0.94
VEGF₁₂₁b and VEGF₁₆₅b are weakly angiogenic isoforms of VEGF-A. Mol Cancer (2010) 0.94
CL100 expression is down-regulated in advanced epithelial ovarian cancer and its re-expression decreases its malignant potential. Oncogene (2002) 0.93
Effects of acute hypoxia and lipopolysaccharide on nitric oxide synthase-2 expression in acute lung injury. Am J Respir Crit Care Med (2003) 0.92
Combined vaccination with idiotype-pulsed allogeneic dendritic cells and soluble protein idiotype for multiple myeloma patients relapsing after reduced-intensity conditioning allogeneic stem cell transplantation. Leuk Lymphoma (2006) 0.92
In vivo evaluation of a new embolic spherical particle (HepaSphere) in a kidney animal model. Cardiovasc Intervent Radiol (2008) 0.92
Alpha CP-4, encoded by a putative tumor suppressor gene at 3p21, but not its alternative splice variant alpha CP-4a, is underexpressed in lung cancer. Cancer Res (2004) 0.92
Patterns of response after preoperative treatment in gastric cancer. Int J Radiat Oncol Biol Phys (2010) 0.91
Development of a novel splice array platform and its application in the identification of alternative splice variants in lung cancer. BMC Genomics (2010) 0.91
A new palliative care consultation team at the oncology department of a university hospital: an assessment of initial efficiency and effectiveness. Support Care Cancer (2012) 0.90
Characterization of cisplatin cytotoxicity delivered from PLGA-systems. Eur J Pharm Biopharm (2007) 0.90
Adrenomedullin is a cross-talk molecule that regulates tumor and mast cell function during human carcinogenesis. Am J Pathol (2006) 0.90
Expression of alpha CP-4 inhibits cell cycle progression and suppresses tumorigenicity of lung cancer cells. Int J Cancer (2008) 0.90
Primary bone lymphoma of the mandible and thyroid incidentaloma identified by FDG PET/CT: a case report. Cases J (2009) 0.90
Quantification of lung damage in an elastase-induced mouse model of emphysema. Int J Biomed Imaging (2012) 0.90
Individual nodule tracking in micro-CT images of a longitudinal lung cancer mouse model. Med Image Anal (2013) 0.89
Four-week neoadjuvant intensity-modulated radiation therapy with concurrent capecitabine and oxaliplatin in locally advanced rectal cancer patients: a validation phase II trial. Int J Radiat Oncol Biol Phys (2011) 0.89
Identification of novel deregulated RNA metabolism-related genes in non-small cell lung cancer. PLoS One (2012) 0.88
Longitudinal study of a mouse model of chronic pulmonary inflammation using breath hold gated micro-CT. Eur Radiol (2010) 0.88
EWS/FLI-1 oncoprotein subtypes impose different requirements for transformation and metastatic activity in a murine model. J Mol Med (Berl) (2007) 0.88
Investigation of complement activation product c4d as a diagnostic and prognostic biomarker for lung cancer. J Natl Cancer Inst (2013) 0.88
MicroRNA-21 predicts response to preoperative chemoradiotherapy in locally advanced rectal cancer. Int J Colorectal Dis (2015) 0.88
Adrenomedullin expression in a rat model of acute lung injury induced by hypoxia and LPS. Am J Physiol Lung Cell Mol Physiol (2004) 0.87
Adrenomedullin functions as an important tumor survival factor in human carcinogenesis. Microsc Res Tech (2002) 0.87
Cortactin (CTTN) overexpression in osteosarcoma correlates with advanced stage and reduced survival. Cancer Biomark (2012) 0.87