Published in Cancer Res on July 15, 2003
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Nonlinear modelling of cancer: bridging the gap between cells and tumours. Nonlinearity (2010) 2.08
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The warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation. Cancer Res (2008) 1.53
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Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2. Neuro Oncol (2008) 1.27
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The pivotal roles of mitochondria in cancer: Warburg and beyond and encouraging prospects for effective therapies. Biochim Biophys Acta (2010) 1.22
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3-Bromopyruvate (3BP) a fast acting, promising, powerful, specific, and effective "small molecule" anti-cancer agent taken from labside to bedside: introduction to a special issue. J Bioenerg Biomembr (2012) 1.09
The role of IDH1 mutated tumour cells in secondary glioblastomas: an evolutionary game theoretical view. Phys Biol (2011) 1.09
Lactate and malignant tumors: a therapeutic target at the end stage of glycolysis. J Bioenerg Biomembr (2007) 1.08
Classifying the evolutionary and ecological features of neoplasms. Nat Rev Cancer (2017) 1.07
Involvement of mitophagy in oncogenic K-Ras-induced transformation: overcoming a cellular energy deficit from glucose deficiency. Autophagy (2011) 1.06
How does cancer cell metabolism affect tumor migration and invasion? Cell Adh Migr (2013) 1.04
Derlin-1 is overexpressed in human breast carcinoma and protects cancer cells from endoplasmic reticulum stress-induced apoptosis. Breast Cancer Res (2008) 1.02
Cancer across the tree of life: cooperation and cheating in multicellularity. Philos Trans R Soc Lond B Biol Sci (2015) 1.00
Clinicopathological and biological significance of human voltage-gated proton channel Hv1 protein overexpression in breast cancer. J Biol Chem (2012) 0.99
The evolutionary impact of androgen levels on prostate cancer in a multi-scale mathematical model. Biol Direct (2010) 0.97
A mathematical model of tumour and blood pHe regulation: The HCO3-/CO2 buffering system. Math Biosci (2010) 0.97
A 2D mechanistic model of breast ductal carcinoma in situ (DCIS) morphology and progression. J Theor Biol (2009) 0.96
Tumour-stromal interactions in acid-mediated invasion: a mathematical model. J Theor Biol (2010) 0.94
Widefield optical imaging of changes in uptake of glucose and tissue extracellular pH in head and neck cancer. Cancer Prev Res (Phila) (2014) 0.92
Dispersal evolution in neoplasms: the role of disregulated metabolism in the evolution of cell motility. Cancer Prev Res (Phila) (2011) 0.91
Mathematical Oncology: How Are the Mathematical and Physical Sciences Contributing to the War on Breast Cancer? Curr Breast Cancer Rep (2010) 0.88
Changing the energy of an immune response. Am J Clin Exp Immunol (2013) 0.88
Human voltage-gated proton channel hv1: a new potential biomarker for diagnosis and prognosis of colorectal cancer. PLoS One (2013) 0.87
Guanylyl cyclase C in colorectal cancer: susceptibility gene and potential therapeutic target. Future Oncol (2009) 0.87
3-Bromopyruvate antagonizes effects of lactate and pyruvate, synergizes with citrate and exerts novel anti-glioma effects. J Bioenerg Biomembr (2012) 0.87
Case report: Sodium dichloroacetate (DCA) inhibition of the "Warburg Effect" in a human cancer patient: complete response in non-Hodgkin's lymphoma after disease progression with rituximab-CHOP. J Bioenerg Biomembr (2012) 0.86
Tumor physiology and charge dynamics of anticancer drugs: implications for camptothecin-based drug development. Curr Med Chem (2011) 0.86
Hypoxia and metabolic adaptation of cancer cells. Oncogenesis (2016) 0.86
Nutritional limitation sensitizes mammalian cells to GSK-3β inhibitors and leads to growth impairment. Am J Pathol (2011) 0.84
Biological factors, tumor growth kinetics, and survival after metastasectomy for pulmonary melanoma. Ann Surg Oncol (2009) 0.84
Dysregulated bioenergetics: a key regulator of joint inflammation. Ann Rheum Dis (2016) 0.84
Metabolic reprogramming of alloantigen-activated T cells after hematopoietic cell transplantation. J Clin Invest (2016) 0.83
Variable toxicological response to the loss of OXPHOS through 1-methyl-4-phenylpyridinium-induced mitochondrial damage and anoxia in diverse neural immortal cell lines. Cell Biol Toxicol (2010) 0.81
Progressive increase of glucose transporter-3 (GLUT-3) expression in estrogen-induced breast carcinogenesis. Clin Transl Oncol (2012) 0.78
Water extract of brewers' rice induces apoptosis in human colorectal cancer cells via activation of caspase-3 and caspase-8 and downregulates the Wnt/β-catenin downstream signaling pathway in brewers' rice-treated rats with azoxymethane-induced colon carcinogenesis. BMC Complement Altern Med (2015) 0.78
Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression. Carcinogenesis (2015) 0.77
Ion transporters in brain tumors. Curr Med Chem (2015) 0.77
BACPTDP: a water-soluble camptothecin pro-drug with enhanced activity in hypoxic/acidic tumors. Cancer Chemother Pharmacol (2010) 0.77
An algorithm for molecular dissection of tumor progression. J Math Biol (2004) 0.77
Heterogeneity and proliferation of invasive cancer subclones in game theory models of the Warburg effect. Cell Prolif (2015) 0.77
A mathematical model for the onset of avascular tumor growth in response to the loss of p53 function. Cancer Inform (2007) 0.76
Inhibitory effect of a standardized pomegranate fruit extract on Wnt signalling in 1, 2-dimethylhydrazine induced rat colon carcinogenesis. Dig Dis Sci (2013) 0.76
Lactate, a Neglected Factor for Diabetes and Cancer Interaction. Mediators Inflamm (2016) 0.75
Characterisation of bioenergetic pathways and related regulators by multiple assays in human tumour cells. Cancer Cell Int (2016) 0.75
Leaky vessels as a potential source of stromal acidification in tumours. J Theor Biol (2010) 0.75
Cancer treatment scheduling and dynamic heterogeneity in social dilemmas of tumour acidity and vasculature. Br J Cancer (2017) 0.75
ERK/Drp1-dependent mitochondrial fission is involved in the MSC-induced drug resistance of T-cell acute lymphoblastic leukemia cells. Cell Death Dis (2016) 0.75
Aggregation Effects and Population-based dynamics as a source of therapy resistance in cancer. IEEE Trans Biomed Eng (2016) 0.75
Glycolytic inhibitors 2-deoxyglucose and 3-bromopyruvate synergize with photodynamic therapy respectively to inhibit cell migration. J Bioenerg Biomembr (2015) 0.75
A cellular automaton model examining the effects of oxygen, hydrogen ions and lactate on early tumour growth. J Math Biol (2013) 0.75