Published in Zhonghua Wai Ke Za Zhi on April 01, 2003
PIRSF: family classification system at the Protein Information Resource. Nucleic Acids Res (2004) 19.62
The Protein Information Resource: an integrated public resource of functional annotation of proteins. Nucleic Acids Res (2002) 12.20
The Protein Information Resource. Nucleic Acids Res (2003) 11.17
PubChem: a public information system for analyzing bioactivities of small molecules. Nucleic Acids Res (2009) 11.05
Representative proteomes: a stable, scalable and unbiased proteome set for sequence analysis and functional annotation. PLoS One (2011) 5.64
The pediatric preclinical testing program: description of models and early testing results. Pediatr Blood Cancer (2007) 5.28
Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heart. Nat Biotechnol (2005) 5.27
An overview of the PubChem BioAssay resource. Nucleic Acids Res (2009) 4.75
Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition. Proc Natl Acad Sci U S A (2008) 4.07
Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock. Cell (2004) 3.98
A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice. Nature (2004) 3.90
PubChem's BioAssay Database. Nucleic Acids Res (2011) 3.74
The Protein Ontology: a structured representation of protein forms and complexes. Nucleic Acids Res (2010) 3.74
BioThesaurus: a web-based thesaurus of protein and gene names. Bioinformatics (2005) 3.43
CXCL12 / CXCR4 / CXCR7 chemokine axis and cancer progression. Cancer Metastasis Rev (2010) 3.24
Predicting protein-protein interactions based only on sequences information. Proc Natl Acad Sci U S A (2007) 3.06
pH-dependent entry of severe acute respiratory syndrome coronavirus is mediated by the spike glycoprotein and enhanced by dendritic cell transfer through DC-SIGN. J Virol (2004) 3.04
Coordination of Rab8 and Rab11 in primary ciliogenesis. Proc Natl Acad Sci U S A (2010) 2.88
S-nitrosohemoglobin deficiency: a mechanism for loss of physiological activity in banked blood. Proc Natl Acad Sci U S A (2007) 2.77
Spider silk fibers spun from soluble recombinant silk produced in mammalian cells. Science (2002) 2.69
Identification of the enzymatic mechanism of nitroglycerin bioactivation. Proc Natl Acad Sci U S A (2002) 2.65
Heterologous envelope immunogens contribute to AIDS vaccine protection in rhesus monkeys. J Virol (2004) 2.63
Replication-defective adenovirus serotype 5 vectors elicit durable cellular and humoral immune responses in nonhuman primates. J Virol (2005) 2.61
Amine-controlled assembly of metal-sulfite architecture from 1D chains to 3D framework. Inorg Chem (2007) 2.57
Plasmon-controlled fluorescence: a new paradigm in fluorescence spectroscopy. Analyst (2008) 2.45
Multiclade human immunodeficiency virus type 1 envelope immunogens elicit broad cellular and humoral immunity in rhesus monkeys. J Virol (2005) 2.40
Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation. Nat Cell Biol (2010) 2.37
The yak genome and adaptation to life at high altitude. Nat Genet (2012) 2.34
Characterization of sleep in zebrafish and insomnia in hypocretin receptor mutants. PLoS Biol (2007) 2.34
Early detection of lung adenocarcinoma in sputum by a panel of microRNA markers. Int J Cancer (2010) 2.20
An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation. Proc Natl Acad Sci U S A (2005) 2.18
Dual-modality monitoring of targeted intraarterial delivery of mesenchymal stem cells after transient ischemia. Stroke (2008) 2.18
PubChem BioAssay: 2014 update. Nucleic Acids Res (2013) 2.14
14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelial-mesenchymal transition. Cancer Cell (2009) 2.09
Immunogenicity of multiple gene and clade human immunodeficiency virus type 1 DNA vaccines. J Virol (2003) 2.09
Exo70 interacts with phospholipids and mediates the targeting of the exocyst to the plasma membrane. EMBO J (2007) 2.03
Human epithelial cancers secrete immunoglobulin g with unidentified specificity to promote growth and survival of tumor cells. Cancer Res (2003) 2.00
Global transcriptional programs reveal a carbon source foraging strategy by Escherichia coli. J Biol Chem (2005) 2.00
Membrane association and functional regulation of Sec3 by phospholipids and Cdc42. J Cell Biol (2008) 1.99
DNA-nanoparticle superlattices formed from anisotropic building blocks. Nat Mater (2010) 1.92
Monocyte chemotactic protein-1 (MCP-1) acts as a paracrine and autocrine factor for prostate cancer growth and invasion. Prostate (2006) 1.90
Targeted cardiac overexpression of A20 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction. Circulation (2007) 1.88
Synthesis, structure, and luminescent properties of hybrid inorganic-organic framework materials formed by lead aromatic carboxylates: inorganic connectivity variation from 0D to 3D. Inorg Chem (2009) 1.85
LEAFY COTYLEDON1 is a key regulator of fatty acid biosynthesis in Arabidopsis. Plant Physiol (2008) 1.79
Monocyte chemotactic protein-1 mediates prostate cancer-induced bone resorption. Cancer Res (2007) 1.79
An improved algorithm to generate a Wi-Fi fingerprint database for indoor positioning. Sensors (Basel) (2013) 1.78
Neutralizing antibodies elicited by immunization of monkeys with DNA plasmids and recombinant adenoviral vectors expressing human immunodeficiency virus type 1 proteins. J Virol (2005) 1.78
Autophagy is a therapeutic target in anticancer drug resistance. Biochim Biophys Acta (2010) 1.77
PI3K pathway activation results in low efficacy of both trastuzumab and lapatinib. BMC Cancer (2011) 1.73
Overweight is associated with decreased cognitive functioning among school-age children and adolescents. Obesity (Silver Spring) (2008) 1.71
Exo70 interacts with the Arp2/3 complex and regulates cell migration. Nat Cell Biol (2006) 1.70
The RABIT: a rapid automated biodosimetry tool for radiological triage. Health Phys (2010) 1.69
CRISPR typing and subtyping for improved laboratory surveillance of Salmonella infections. PLoS One (2012) 1.68
A multicenter, randomized, double-blind, parallel-group, placebo-controlled study of the effects of qili qiangxin capsules in patients with chronic heart failure. J Am Coll Cardiol (2013) 1.66
Very high fructose intake increases serum LDL-cholesterol and total cholesterol: a meta-analysis of controlled feeding trials. J Nutr (2013) 1.65
Prescribing of smoking cessation medication in England since the introduction of varenicline. Addiction (2011) 1.65
Findings from 2010 Global Adult Tobacco Survey: implementation of MPOWER policy in China. Biomed Environ Sci (2010) 1.65
Associations between body mass index and the prevalence of low micronutrient levels among US adults. MedGenMed (2006) 1.63
Multifidus muscle changes and clinical effects of one-level posterior lumbar interbody fusion: minimally invasive procedure versus conventional open approach. Eur Spine J (2009) 1.62
IL-4 and IL-12 regulate proteoglycan-induced arthritis through Stat-dependent mechanisms. J Immunol (2002) 1.61
The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases. Chem Biol (2005) 1.61
BETA2/NeuroD1 null mice: a new model for transcription factor-dependent photoreceptor degeneration. J Neurosci (2003) 1.61
Inhibition of interleukin-6 with CNTO328, an anti-interleukin-6 monoclonal antibody, inhibits conversion of androgen-dependent prostate cancer to an androgen-independent phenotype in orchiectomized mice. Cancer Res (2006) 1.59
AutismKB: an evidence-based knowledgebase of autism genetics. Nucleic Acids Res (2011) 1.59
Involvement of human natural killer cells in asthma pathogenesis: natural killer 2 cells in type 2 cytokine predominance. J Allergy Clin Immunol (2005) 1.59
SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with the plasma membrane. Nat Commun (2012) 1.58
Automated protein structure modeling in CASP9 by I-TASSER pipeline combined with QUARK-based ab initio folding and FG-MD-based structure refinement. Proteins (2011) 1.58
Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism. Cancer Res (2005) 1.56
Dendrite-free lithium deposition via self-healing electrostatic shield mechanism. J Am Chem Soc (2013) 1.56
Recombinant human butyrylcholinesterase from milk of transgenic animals to protect against organophosphate poisoning. Proc Natl Acad Sci U S A (2007) 1.54
4,4'-Thiodipyridinium tetrachlorocopper(II). Acta Crystallogr C (2004) 1.54
Identifying selected regions from heterozygosity and divergence using a light-coverage genomic dataset from two human populations. PLoS One (2008) 1.54
Postsynaptically synthesized prostaglandin E2 (PGE2) modulates hippocampal synaptic transmission via a presynaptic PGE2 EP2 receptor. J Neurosci (2005) 1.52
No-reflow protection and long-term efficacy for acute myocardial infarction with Tongxinluo: a randomized double-blind placebo-controlled multicenter clinical trial (ENLEAT Trial). Chin Med J (Engl) (2010) 1.51
Can data from primary care medical records be used to monitor national smoking prevalence? J Epidemiol Community Health (2011) 1.50
Increased susceptibility to liver injury in hepatitis B virus transgenic mice involves NKG2D-ligand interaction and natural killer cells. Hepatology (2007) 1.49
A piggyBac transposon-based genome-wide library of insertionally mutated Blm-deficient murine ES cells. Genome Res (2009) 1.48
Lethal giant larvae proteins interact with the exocyst complex and are involved in polarized exocytosis. J Cell Biol (2005) 1.47
Establishment and evaluation of a swine model of acute myocardial infarction and reperfusion-ventricular fibrillation-cardiac arrest using the interventional technique. J Chin Med Assoc (2013) 1.47
Influence of environmental factors on prevalence, symptoms, and pathologic process of chronic prostatitis/chronic pelvic pain syndrome in northwest China. Urology (2011) 1.46
Adapting the γ-H2AX assay for automated processing in human lymphocytes. 1. Technological aspects. Radiat Res (2010) 1.46
Cloning, sequencing, analysis, and heterologous expression of the fredericamycin biosynthetic gene cluster from Streptomyces griseus. J Am Chem Soc (2005) 1.46
Endovascular stenting vs. extrathoracic surgical bypass for symptomatic subclavian steal syndrome. J Endovasc Ther (2012) 1.45
Widespread and stable pancreatic gene transfer by adeno-associated virus vectors via different routes. Diabetes (2006) 1.45
Measuring the glycemic index of foods: interlaboratory study. Am J Clin Nutr (2008) 1.44
Mitotic phosphorylation of Exo84 disrupts exocyst assembly and arrests cell growth. J Cell Biol (2013) 1.43
P25alpha immunoreactive but alpha-synuclein immunonegative neuronal inclusions in multiple system atrophy. Acta Neuropathol (2006) 1.43
Diet-derived phenolic acids regulate osteoblast and adipocyte lineage commitment and differentiation in young mice. J Bone Miner Res (2014) 1.43
Cyclical regulation of the exocyst and cell polarity determinants for polarized cell growth. Mol Biol Cell (2005) 1.42
RANKL acts directly on RANK-expressing prostate tumor cells and mediates migration and expression of tumor metastasis genes. Prostate (2008) 1.42
Enhanced mucosal immunoglobulin A response of intranasal adenoviral vector human immunodeficiency virus vaccine and localization in the central nervous system. J Virol (2003) 1.41
The values of thin sections and three-dimensional reconstruction in the sellar region. World Neurosurg (2011) 1.40
Selective targeting of gold nanorods at the mitochondria of cancer cells: implications for cancer therapy. Nano Lett (2010) 1.40
A Phase II, randomized, double-blind, multicenter, based on standard therapy, placebo-controlled study of the efficacy and safety of recombinant human neuregulin-1 in patients with chronic heart failure. J Am Coll Cardiol (2010) 1.40
Acute and reversible cardiomyopathy provoked by stress in a Chinese woman. Chin Med J (Engl) (2008) 1.39
Predicting drug-target interaction networks based on functional groups and biological features. PLoS One (2010) 1.39
Involvement of sphingoid bases in mediating reactive oxygen intermediate production and programmed cell death in Arabidopsis. Cell Res (2007) 1.38
New insights into the antifibrotic effects of sorafenib on hepatic stellate cells and liver fibrosis. J Hepatol (2010) 1.38
Efficacy and safety of accelerated partial breast irradiation after breast-conserving surgery: a meta-analysis of published comparative studies. Breast J (2013) 1.38
A neurofibromatosis type 1 patient with thoracic encapsulated fluid and intracranial hypotension syndrome: a case report. Neurologist (2011) 1.38