Published in Nucleic Acids Res on December 01, 2011
SFARI Gene 2.0: a community-driven knowledgebase for the autism spectrum disorders (ASDs). Mol Autism (2013) 1.48
Autism-associated promoter variant in MET impacts functional and structural brain networks. Neuron (2012) 1.29
CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors. Proc Natl Acad Sci U S A (2014) 1.16
Brain transcriptional and epigenetic associations with autism. PLoS One (2012) 1.13
Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons. Mol Psychiatry (2014) 1.09
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Genome-wide identification of transcriptional targets of RORA reveals direct regulation of multiple genes associated with autism spectrum disorder. Mol Autism (2013) 1.04
A direct molecular link between the autism candidate gene RORa and the schizophrenia candidate MIR137. Sci Rep (2014) 1.00
EpilepsyGene: a genetic resource for genes and mutations related to epilepsy. Nucleic Acids Res (2014) 0.99
An inside job: how endosomal Na(+)/H(+) exchangers link to autism and neurological disease. Front Cell Neurosci (2014) 0.96
Integrated analysis of whole-exome sequencing and transcriptome profiling in males with autism spectrum disorders. Mol Autism (2015) 0.95
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Genetics studies indicate that neural induction and early neuronal maturation are disturbed in autism. Front Cell Neurosci (2014) 0.89
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Autworks: a cross-disease network biology application for Autism and related disorders. BMC Med Genomics (2012) 0.88
Application of custom-designed oligonucleotide array CGH in 145 patients with autistic spectrum disorders. Eur J Hum Genet (2012) 0.88
Prenatal expression of MET receptor tyrosine kinase in the fetal mouse dorsal raphe nuclei and the visceral motor/sensory brainstem. Dev Neurosci (2013) 0.87
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Family-based association study of ZNF533, DOCK4 and IMMP2L gene polymorphisms linked to autism in a northeastern Chinese Han population. J Zhejiang Univ Sci B (2014) 0.83
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Genome-wide analysis identifies a role for common copy number variants in specific language impairment. Eur J Hum Genet (2015) 0.82
Disruption of an Evolutionarily Novel Synaptic Expression Pattern in Autism. PLoS Biol (2016) 0.81
CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in neurodevelopment. Mol Autism (2015) 0.81
Protein signatures of oxidative stress response in a patient specific cell line model for autism. Mol Autism (2014) 0.80
PCOSKB: A KnowledgeBase on genes, diseases, ontology terms and biochemical pathways associated with PolyCystic Ovary Syndrome. Nucleic Acids Res (2015) 0.80
Investigation of sex differences in the expression of RORA and its transcriptional targets in the brain as a potential contributor to the sex bias in autism. Mol Autism (2015) 0.80
Shared Pathways Among Autism Candidate Genes Determined by Co-expression Network Analysis of the Developing Human Brain Transcriptome. J Mol Neurosci (2015) 0.79
Systems biology of complex symptom profiles: capturing interactivity across behavior, brain and immune regulation. Brain Behav Immun (2012) 0.79
Salivary miRNA profiles identify children with autism spectrum disorder, correlate with adaptive behavior, and implicate ASD candidate genes involved in neurodevelopment. BMC Pediatr (2016) 0.78
Glutamatergic candidate genes in autism spectrum disorder: an overview. J Neural Transm (Vienna) (2014) 0.78
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Genes with high penetrance for syndromic and non-syndromic autism typically function within the nucleus and regulate gene expression. Mol Autism (2016) 0.77
A systematic variant annotation approach for ranking genes associated with autism spectrum disorders. Mol Autism (2016) 0.76
Transcriptomic signatures of neuronal differentiation and their association with risk genes for autism spectrum and related neuropsychiatric disorders. Transl Psychiatry (2016) 0.75
A case report of Chinese brothers with inherited MECP2-containing duplication: autism and intellectual disability, but not seizures or respiratory infections. BMC Med Genet (2012) 0.75
Neonicotinoid Insecticides Alter the Gene Expression Profile of Neuron-Enriched Cultures from Neonatal Rat Cerebellum. Int J Environ Res Public Health (2016) 0.75
NERI: network-medicine based integrative approach for disease gene prioritization by relative importance. BMC Bioinformatics (2015) 0.75
Mutation of the CH1 Domain in the Histone Acetyltransferase CREBBP Results in Autism-Relevant Behaviors in Mice. PLoS One (2016) 0.75
Lysine Acetylation and Deacetylation in Brain Development and Neuropathies. Genomics Proteomics Bioinformatics (2017) 0.75
CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells. Mol Autism (2017) 0.75
Next-gen sequencing identifies non-coding variation disrupting miRNA-binding sites in neurological disorders. Mol Psychiatry (2017) 0.75
Postzygotic single-nucleotide mosaicisms contribute to the etiology of autism spectrum disorder and autistic traits and the origin of mutations. Hum Mutat (2017) 0.75
Autism-like behavior caused by deletion of vaccinia-related kinase 3 is improved by TrkB stimulation. J Exp Med (2017) 0.75
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol (2009) 235.12
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc (2009) 137.99
Mapping and quantifying mammalian transcriptomes by RNA-Seq. Nat Methods (2008) 126.81
TopHat: discovering splice junctions with RNA-Seq. Bioinformatics (2009) 81.13
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol (2010) 75.21
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A (2009) 54.68
Alternative isoform regulation in human tissue transcriptomes. Nature (2008) 52.76
KEGG for linking genomes to life and the environment. Nucleic Acids Res (2007) 49.37
A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci U S A (2004) 44.81
KEGG for representation and analysis of molecular networks involving diseases and drugs. Nucleic Acids Res (2009) 28.60
PANTHER: a library of protein families and subfamilies indexed by function. Genome Res (2003) 21.64
Human Protein Reference Database--2009 update. Nucleic Acids Res (2008) 21.25
The UCSC Genome Browser database: update 2011. Nucleic Acids Res (2010) 16.24
Structural variation of chromosomes in autism spectrum disorder. Am J Hum Genet (2008) 15.51
DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res (2010) 13.68
PID: the Pathway Interaction Database. Nucleic Acids Res (2008) 12.92
Autism as a strongly genetic disorder: evidence from a British twin study. Psychol Med (1995) 12.70
Advances in autism genetics: on the threshold of a new neurobiology. Nat Rev Genet (2008) 12.18
FlyBase: enhancing Drosophila Gene Ontology annotations. Nucleic Acids Res (2008) 12.15
Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. Nat Genet (2007) 12.13
The genetic association database. Nat Genet (2004) 11.29
Reactome: a database of reactions, pathways and biological processes. Nucleic Acids Res (2010) 11.23
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2010) 10.97
Transcriptomic analysis of autistic brain reveals convergent molecular pathology. Nature (2011) 10.16
Initial impact of the sequencing of the human genome. Nature (2011) 9.18
miRWalk--database: prediction of possible miRNA binding sites by "walking" the genes of three genomes. J Biomed Inform (2011) 8.50
The BioGRID Interaction Database: 2011 update. Nucleic Acids Res (2010) 8.46
Expansion of the BioCyc collection of pathway/genome databases to 160 genomes. Nucleic Acids Res (2005) 7.13
Genetic heritability and shared environmental factors among twin pairs with autism. Arch Gen Psychiatry (2011) 6.98
Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. Nat Genet (2008) 6.71
Prevalence of autism spectrum disorders in a total population sample. Am J Psychiatry (2011) 5.85
The database of experimentally supported targets: a functional update of TarBase. Nucleic Acids Res (2008) 5.65
A guide to the Proteomics Identifications Database proteomics data repository. Proteomics (2009) 5.63
Etiological heterogeneity in autism spectrum disorders: more than 100 genetic and genomic disorders and still counting. Brain Res (2010) 5.50
Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing. Clin Pharmacol Ther (2011) 5.44
The genetics of autism. Pediatrics (2004) 4.93
Annotating the human genome with Disease Ontology. BMC Genomics (2009) 4.71
Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses. Neuron (2011) 4.66
The Mouse Genome Database (MGD): premier model organism resource for mammalian genomics and genetics. Nucleic Acids Res (2010) 4.58
KOBAS 2.0: a web server for annotation and identification of enriched pathways and diseases. Nucleic Acids Res (2011) 4.44
Development of bioinformatics resources for display and analysis of copy number and other structural variants in the human genome. Cytogenet Genome Res (2006) 3.68
The genetics of autistic disorders and its clinical relevance: a review of the literature. Mol Psychiatry (2006) 3.63
A high-confidence human plasma proteome reference set with estimated concentrations in PeptideAtlas. Mol Cell Proteomics (2011) 3.37
Dynamic transcriptomes during neural differentiation of human embryonic stem cells revealed by short, long, and paired-end sequencing. Proc Natl Acad Sci U S A (2010) 3.28
Prevalence of parent-reported diagnosis of autism spectrum disorder among children in the US, 2007. Pediatrics (2009) 3.24
The Comparative Toxicogenomics Database: update 2011. Nucleic Acids Res (2010) 3.15
ZFIN: enhancements and updates to the Zebrafish Model Organism Database. Nucleic Acids Res (2010) 3.02
AutDB: a gene reference resource for autism research. Nucleic Acids Res (2008) 2.62
From disease ontology to disease-ontology lite: statistical methods to adapt a general-purpose ontology for the test of gene-ontology associations. Bioinformatics (2009) 2.37
Genetics of autism spectrum disorder. Eur J Hum Genet (2006) 2.24
Genome-wide in silico identification and analysis of cis natural antisense transcripts (cis-NATs) in ten species. Nucleic Acids Res (2006) 2.21
The Allen Brain Atlas: 5 years and beyond. Nat Rev Neurosci (2009) 2.00
The genetics of child psychiatric disorders: focus on autism and Tourette syndrome. Neuron (2010) 1.57
SFARI Gene: an evolving database for the autism research community. Dis Model Mech (2010) 1.50
A multi-dimensional evidence-based candidate gene prioritization approach for complex diseases-schizophrenia as a case. Bioinformatics (2009) 1.50
Biomolecular interaction network database. Brief Bioinform (2005) 1.27
Current developments in the genetics of autism: from phenome to genome. J Neuropathol Exp Neurol (2008) 1.26
Autism Genetic Database (AGD): a comprehensive database including autism susceptibility gene-CNVs integrated with known noncoding RNAs and fragile sites. BMC Med Genet (2009) 1.11
WebLab: a data-centric, knowledge-sharing bioinformatic platform. Nucleic Acids Res (2009) 1.00
A comprehensive resource for integrating and displaying protein post-translational modifications. BMC Res Notes (2009) 0.91
CPC: assess the protein-coding potential of transcripts using sequence features and support vector machine. Nucleic Acids Res (2007) 5.88
Automated genome annotation and pathway identification using the KEGG Orthology (KO) as a controlled vocabulary. Bioinformatics (2005) 4.60
KOBAS 2.0: a web server for annotation and identification of enriched pathways and diseases. Nucleic Acids Res (2011) 4.44
DATF: a database of Arabidopsis transcription factors. Bioinformatics (2005) 4.34
A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice. Nature (2004) 3.90
Mineralocorticoid receptor antagonism in the treatment of chronic central serous chorioretinopathy: a pilot study. Retina (2013) 3.42
Controlling cell behavior electrically: current views and future potential. Physiol Rev (2005) 3.34
CEAS: cis-regulatory element annotation system. Nucleic Acids Res (2006) 3.15
CTLs are targeted to kill beta cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope. J Clin Invest (2008) 3.11
Identification of multivesicular bodies as prevacuolar compartments in Nicotiana tabacum BY-2 cells. Plant Cell (2004) 3.08
Serial determination of glomerular filtration rate in conscious mice using FITC-inulin clearance. Am J Physiol Renal Physiol (2003) 3.06
pH-dependent entry of severe acute respiratory syndrome coronavirus is mediated by the spike glycoprotein and enhanced by dendritic cell transfer through DC-SIGN. J Virol (2004) 3.04
Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody. Science (2013) 2.95
Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism. Cell (2013) 2.94
Eukaryotic regulatory element conservation analysis and identification using comparative genomics. Genome Res (2004) 2.84
Induction of pluripotency in mouse somatic cells with lineage specifiers. Cell (2013) 2.69
Spider silk fibers spun from soluble recombinant silk produced in mammalian cells. Science (2002) 2.69
Heterologous envelope immunogens contribute to AIDS vaccine protection in rhesus monkeys. J Virol (2004) 2.63
Replication-defective adenovirus serotype 5 vectors elicit durable cellular and humoral immune responses in nonhuman primates. J Virol (2005) 2.61
KOBAS server: a web-based platform for automated annotation and pathway identification. Nucleic Acids Res (2006) 2.59
Multiclade human immunodeficiency virus type 1 envelope immunogens elicit broad cellular and humoral immunity in rhesus monkeys. J Virol (2005) 2.40
Clinical characteristics of 26 human cases of highly pathogenic avian influenza A (H5N1) virus infection in China. PLoS One (2008) 2.28
An analysis of the indications for cesarean section in a teaching hospital in China. Eur J Obstet Gynecol Reprod Biol (2013) 2.26
Genome-wide in silico identification and analysis of cis natural antisense transcripts (cis-NATs) in ten species. Nucleic Acids Res (2006) 2.21
A nonsynonymous SNP in human cytosolic sialidase in a small Asian population results in reduced enzyme activity: potential link with severe adverse reactions to oseltamivir. Cell Res (2007) 2.13
DRTF: a database of rice transcription factors. Bioinformatics (2006) 2.10
Immunogenicity of multiple gene and clade human immunodeficiency virus type 1 DNA vaccines. J Virol (2003) 2.09
Computational tools for copy number variation (CNV) detection using next-generation sequencing data: features and perspectives. BMC Bioinformatics (2013) 2.07
Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways. Blood (2010) 1.92
Targeted cardiac overexpression of A20 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction. Circulation (2007) 1.88
Neutralizing antibodies elicited by immunization of monkeys with DNA plasmids and recombinant adenoviral vectors expressing human immunodeficiency virus type 1 proteins. J Virol (2005) 1.78
Rha1, an Arabidopsis Rab5 homolog, plays a critical role in the vacuolar trafficking of soluble cargo proteins. Plant Cell (2003) 1.67
Prescribing of smoking cessation medication in England since the introduction of varenicline. Addiction (2011) 1.65
Multifidus muscle changes and clinical effects of one-level posterior lumbar interbody fusion: minimally invasive procedure versus conventional open approach. Eur Spine J (2009) 1.62
Application of direct current electric fields to cells and tissues in vitro and modulation of wound electric field in vivo. Nat Protoc (2007) 1.62
Genes and (common) pathways underlying drug addiction. PLoS Comput Biol (2007) 1.57
Recombinant human butyrylcholinesterase from milk of transgenic animals to protect against organophosphate poisoning. Proc Natl Acad Sci U S A (2007) 1.54
Electrical cues regulate the orientation and frequency of cell division and the rate of wound healing in vivo. Proc Natl Acad Sci U S A (2002) 1.52
Can data from primary care medical records be used to monitor national smoking prevalence? J Epidemiol Community Health (2011) 1.50
Pulsed magnetic field induces angiogenesis and improves cardiac function of surgically induced infarcted myocardium in Sprague-Dawley rats. Cardiology (2010) 1.49
Non-invasive measurement of bioelectric currents with a vibrating probe. Nat Protoc (2007) 1.48
Wound healing in rat cornea: the role of electric currents. FASEB J (2005) 1.48
A piggyBac transposon-based genome-wide library of insertionally mutated Blm-deficient murine ES cells. Genome Res (2009) 1.48
Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses. Cell Res (2013) 1.47
The multifunctional human p100 protein 'hooks' methylated ligands. Nat Struct Mol Biol (2007) 1.46
Safety and immunological responses to human mesenchymal stem cell therapy in difficult-to-treat HIV-1-infected patients. AIDS (2013) 1.45
P25alpha immunoreactive but alpha-synuclein immunonegative neuronal inclusions in multiple system atrophy. Acta Neuropathol (2006) 1.43
A modified procedure for velopharyngeal sphincteroplasty in primary cleft palate repair and secondary velopharyngeal incompetence treatment and its preliminary results. J Plast Reconstr Aesthet Surg (2006) 1.43
Acanthamoeba migration in an electric field. Invest Ophthalmol Vis Sci (2013) 1.42
Enhanced mucosal immunoglobulin A response of intranasal adenoviral vector human immunodeficiency virus vaccine and localization in the central nervous system. J Virol (2003) 1.41
MicroRNA expression and regulation in human, chimpanzee, and macaque brains. PLoS Genet (2011) 1.40
Toll-like receptors expressed by dermal fibroblasts contribute to hypertrophic scarring. J Cell Physiol (2011) 1.36
Hominoid-specific de novo protein-coding genes originating from long non-coding RNAs. PLoS Genet (2012) 1.35
Differential expression of the intermediate filament protein nestin during renal development and its localization in adult podocytes. J Am Soc Nephrol (2006) 1.34
NATsDB: Natural Antisense Transcripts DataBase. Nucleic Acids Res (2006) 1.33
A human-specific de novo protein-coding gene associated with human brain functions. PLoS Comput Biol (2010) 1.31
A PiggyBac-based recessive screening method to identify pluripotency regulators. PLoS One (2011) 1.30
Effect of transcription factor GATA-2 on phagocytic activity of alveolar macrophages from Pneumocystis carinii-infected hosts. Infect Immun (2003) 1.29
A suite of web-based programs to search for transcriptional regulatory motifs. Nucleic Acids Res (2004) 1.29
Vesicular zinc promotes presynaptic and inhibits postsynaptic long-term potentiation of mossy fiber-CA3 synapse. Neuron (2011) 1.29
Bladder outlet obstruction: progression from inflammation to fibrosis. BJU Int (2010) 1.28
Prime-boost vaccination with HIV-1 Gag protein and cytosine phosphate guanosine oligodeoxynucleotide, followed by adenovirus, induces sustained and robust humoral and cellular immune responses. J Immunol (2003) 1.27
Coupling of receptor conformation and ligand orientation determine graded activity. Nat Chem Biol (2010) 1.25
SynDB: a Synapse protein DataBase based on synapse ontology. Nucleic Acids Res (2006) 1.25
Enhanced intracellular delivery and improved antitumor efficacy of doxorubicin by sterically stabilized liposomes modified with a synthetic RGD mimetic. J Control Release (2005) 1.24
Amino acids stimulate translation initiation and protein synthesis through an Akt-independent pathway in human skeletal muscle. J Clin Endocrinol Metab (2002) 1.24
A subgroup of MYB transcription factor genes undergoes highly conserved alternative splicing in Arabidopsis and rice. J Exp Bot (2006) 1.23
Lithium treatment inhibits renal GSK-3 activity and promotes cyclooxygenase 2-dependent polyuria. Am J Physiol Renal Physiol (2004) 1.23
Effects of a randomized contingency management intervention on opiate abstinence and retention in methadone maintenance treatment in China. Addiction (2011) 1.22
Viral infection induces expression of novel phased microRNAs from conserved cellular microRNA precursors. PLoS Pathog (2011) 1.22
miR-17-92 cluster microRNAs confers tumorigenicity in multiple myeloma. Cancer Lett (2011) 1.21
An overview of liposome lyophilization and its future potential. J Control Release (2009) 1.20
Nerve regeneration and wound healing are stimulated and directed by an endogenous electrical field in vivo. J Cell Sci (2004) 1.17
HIV-1 subtype B' dictates the AIDS epidemic among paid blood donors in the Henan and Hubei provinces of China. AIDS (2003) 1.16
Golgi polarization in a strong electric field. J Cell Sci (2005) 1.16
Solid lipid nanoparticles (SLNs) to improve oral bioavailability of poorly soluble drugs. J Pharm Pharmacol (2004) 1.15
Retracted Curcumin prevents and reverses murine cardiac hypertrophy. J Clin Invest (2008) 1.15
Rare variants in RTEL1 are associated with familial interstitial pneumonia. Am J Respir Crit Care Med (2015) 1.15
Small applied electric fields guide migration of hippocampal neurons. J Cell Physiol (2008) 1.13
Effects of physiological electric fields on migration of human dermal fibroblasts. J Invest Dermatol (2010) 1.13
Database and analyses of known alternatively spliced genes in plants. Genomics (2003) 1.13
Development of a dissolution medium for nimodipine tablets based on bioavailability evaluation. Eur J Pharm Sci (2004) 1.12
A homozygous mutant embryonic stem cell bank applicable for phenotype-driven genetic screening. Nat Methods (2011) 1.11
Isorhapontigenin, a new resveratrol analog, attenuates cardiac hypertrophy via blocking signaling transduction pathways. Free Radic Biol Med (2005) 1.11
Guided migration of neural stem cells derived from human embryonic stem cells by an electric field. Stem Cells (2012) 1.11
Genome comparison using Gene Ontology (GO) with statistical testing. BMC Bioinformatics (2006) 1.10
Epigallocathechin-3 gallate inhibits cardiac hypertrophy through blocking reactive oxidative species-dependent and -independent signal pathways. Free Radic Biol Med (2006) 1.10
Finding new structural and sequence attributes to predict possible disease association of single amino acid polymorphism (SAP). Bioinformatics (2007) 1.10
A proof-of-concept and drug-drug interaction study of pamapimod, a novel p38 MAP kinase inhibitor, with methotrexate in patients with rheumatoid arthritis. J Clin Pharmacol (2010) 1.10
Discovery of a distinct superfamily of Kunitz-type toxin (KTT) from tarantulas. PLoS One (2008) 1.10
Has electrical growth cone guidance found its potential? Trends Neurosci (2002) 1.09
Resveratrol inhibits beta-amyloid oligomeric cytotoxicity but does not prevent oligomer formation. Neurotoxicology (2009) 1.09
Multichannel monolithic quartz crystal microbalance gas sensor array. Anal Chem (2009) 1.09
Loss of miR-29b following acute ischemic stroke contributes to neural cell death and infarct size. J Cereb Blood Flow Metab (2013) 1.08
SPIRONOLACTONE FOR NONRESOLVING CENTRAL SEROUS CHORIORETINOPATHY: A Randomized Controlled Crossover Study. Retina (2015) 1.08
p25alpha relocalizes in oligodendroglia from myelin to cytoplasmic inclusions in multiple system atrophy. Am J Pathol (2007) 1.08
DC electric fields induce distinct preangiogenic responses in microvascular and macrovascular cells. Arterioscler Thromb Vasc Biol (2004) 1.08
Electrically guiding migration of human induced pluripotent stem cells. Stem Cell Rev (2011) 1.08
Development of a chemically stable 10-hydroxycamptothecin nanosuspensions. Int J Pharm (2009) 1.07