Published in Chromosoma on July 16, 2003
The take and give between retrotransposable elements and their hosts. Annu Rev Genet (2008) 1.86
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics (1989) 105.30
Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science (1999) 36.25
New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae. Yeast (1994) 24.57
Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications. Yeast (1998) 23.00
Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (1999) 19.25
Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors. Science (1987) 17.15
Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell (1998) 8.31
Loss of a yeast telomere: arrest, recovery, and chromosome loss. Cell (1993) 6.83
Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J (1998) 5.79
Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1. Genes Dev (1994) 5.21
The many interfaces of Mre11. Cell (1998) 4.14
Visualizing chromatin dynamics in interphase nuclei. Science (2002) 3.42
Partners and pathwaysrepairing a double-strand break. Trends Genet (2000) 3.39
Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae. Cell (1995) 3.37
Common themes in mechanisms of gene silencing. Mol Cell (2001) 2.88
Replication and segregation of plasmids containing cis-acting regulatory sites of silent mating-type genes in Saccharomyces cerevisiae are controlled by the SIR genes. Mol Cell Biol (1987) 2.68
NEJ1 controls non-homologous end joining in Saccharomyces cerevisiae. Nature (2001) 2.42
A DNA microarray-based genetic screen for nonhomologous end-joining mutants in Saccharomyces cerevisiae. Science (2001) 2.16
Mechanisms of silencing in Saccharomyces cerevisiae. Curr Opin Genet Dev (1998) 2.13
Yeast activators stimulate plant gene expression. Nature (1988) 2.13
Rap1-Sir4 binding independent of other Sir, yKu, or histone interactions initiates the assembly of telomeric heterochromatin in yeast. Genes Dev (2002) 2.12
Nej1p, a cell type-specific regulator of nonhomologous end joining in yeast. Curr Biol (2001) 1.91
Targeting of the yeast Ty5 retrotransposon to silent chromatin is mediated by interactions between integrase and Sir4p. Mol Cell Biol (2001) 1.81
Tagging chromatin with retrotransposons: target specificity of the Saccharomyces Ty5 retrotransposon changes with the chromosomal localization of Sir3p and Sir4p. Genes Dev (1999) 1.47
The Sir proteins of Saccharomyces cerevisiae: mediators of transcriptional silencing and much more. Curr Opin Microbiol (2000) 1.36
Yeast telomere repeat sequence (TRS) improves circular plasmid segregation, and TRS plasmid segregation involves the RAP1 gene product. Mol Cell Biol (1992) 1.29
The yeast silent information regulator Sir4p anchors and partitions plasmids. Mol Cell Biol (1997) 1.21
A single amino acid change in the yeast retrotransposon Ty5 abolishes targeting to silent chromatin. Mol Cell (1998) 1.18
Enhancement of telomere-plasmid segregation by the X-telomere associated sequence in Saccharomyces cerevisiae involves SIR2, SIR3, SIR4 and ABF1. Genetics (1994) 1.08
Telomere-mediated plasmid segregation in Saccharomyces cerevisiae involves gene products required for transcriptional repression at silencers and telomeres. Genetics (1993) 0.96
TEL+CEN antagonism on plasmids involves telomere repeat sequences tracts and gene products that interact with chromosomal telomeres. Chromosoma (1994) 0.84
Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting. Nucleic Acids Res (2011) 16.53
Targeting DNA double-strand breaks with TAL effector nucleases. Genetics (2010) 14.49
Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification. Mol Cell (2008) 11.24
TAL effectors: customizable proteins for DNA targeting. Science (2011) 9.47
Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA). Nat Methods (2010) 8.86
High-frequency modification of plant genes using engineered zinc-finger nucleases. Nature (2009) 7.19
In vivo genome editing using a high-efficiency TALEN system. Nature (2012) 7.11
Unexpected failure rates for modular assembly of engineered zinc fingers. Nat Methods (2008) 6.51
Efficient TALEN-mediated gene knockout in livestock. Proc Natl Acad Sci U S A (2012) 4.99
High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases. Proc Natl Acad Sci U S A (2010) 4.78
TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction. Nucleic Acids Res (2012) 4.45
Simple methods for generating and detecting locus-specific mutations induced with TALENs in the zebrafish genome. PLoS Genet (2012) 4.42
Standardized reagents and protocols for engineering zinc finger nucleases by modular assembly. Nat Protoc (2006) 4.16
ZiFiT (Zinc Finger Targeter): an updated zinc finger engineering tool. Nucleic Acids Res (2010) 3.59
Zinc Finger Targeter (ZiFiT): an engineered zinc finger/target site design tool. Nucleic Acids Res (2007) 3.47
High-frequency homologous recombination in plants mediated by zinc-finger nucleases. Plant J (2005) 3.45
Oligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arrays. Nat Protoc (2009) 3.01
Common physical properties of DNA affecting target site selection of sleeping beauty and other Tc1/mariner transposable elements. J Mol Biol (2002) 2.56
An affinity-based scoring scheme for predicting DNA-binding activities of modularly assembled zinc-finger proteins. Nucleic Acids Res (2008) 2.42
Transcription activator-like effector nucleases enable efficient plant genome engineering. Plant Physiol (2012) 2.36
Zinc Finger Database (ZiFDB): a repository for information on C2H2 zinc fingers and engineered zinc-finger arrays. Nucleic Acids Res (2008) 1.87
Phosphorylation regulates integration of the yeast Ty5 retrotransposon into heterochromatin. Mol Cell (2007) 1.86
TALEN-based gene correction for epidermolysis bullosa. Mol Ther (2013) 1.84
TALEN-engineered AR gene rearrangements reveal endocrine uncoupling of androgen receptor in prostate cancer. Proc Natl Acad Sci U S A (2013) 1.77
Controlling integration specificity of a yeast retrotransposon. Proc Natl Acad Sci U S A (2003) 1.74
The diversity of LTR retrotransposons. Genome Biol (2004) 1.74
Increasing frequencies of site-specific mutagenesis and gene targeting in Arabidopsis by manipulating DNA repair pathways. Genome Res (2013) 1.57
DNA replicons for plant genome engineering. Plant Cell (2014) 1.57
Rapid and efficient gene modification in rice and Brachypodium using TALENs. Mol Plant (2013) 1.56
Chromodomains direct integration of retrotransposons to heterochromatin. Genome Res (2008) 1.39
Targeting G with TAL effectors: a comparison of activities of TALENs constructed with NN and NK repeat variable di-residues. PLoS One (2012) 1.38
Targeted mutagenesis of duplicated genes in soybean with zinc-finger nucleases. Plant Physiol (2011) 1.29
Genomic neighborhoods for Arabidopsis retrotransposons: a role for targeted integration in the distribution of the Metaviridae. Genome Biol (2004) 1.27
Genes of the Pseudoviridae (Ty1/copia retrotransposons). Mol Biol Evol (2002) 1.27
TALEN-mediated editing of the mouse Y chromosome. Nat Biotechnol (2013) 1.26
TAL effectors: highly adaptable phytobacterial virulence factors and readily engineered DNA-targeting proteins. Trends Cell Biol (2013) 1.24
Athila4 of Arabidopsis and Calypso of soybean define a lineage of endogenous plant retroviruses. Genome Res (2002) 1.22
Targeted mutagenesis of Arabidopsis thaliana using engineered TAL effector nucleases. G3 (Bethesda) (2013) 1.19
Comparing zinc finger nucleases and transcription activator-like effector nucleases for gene targeting in Drosophila. G3 (Bethesda) (2013) 1.14
A TALE of two nucleases: gene targeting for the masses? Zebrafish (2011) 1.14
Translational recoding signals between gag and pol in diverse LTR retrotransposons. RNA (2003) 1.10
TAL effector nucleases induce mutations at a pre-selected location in the genome of primary barley transformants. Plant Mol Biol (2013) 1.10
Compact designer TALENs for efficient genome engineering. Nat Commun (2013) 1.06
SIRE1, an endogenous retrovirus family from Glycine max, is highly homogeneous and evolutionarily young. Mol Biol Evol (2003) 1.06
Improved soybean oil quality by targeted mutagenesis of the fatty acid desaturase 2 gene family. Plant Biotechnol J (2014) 1.04
A nucleosomal surface defines an integration hotspot for the Saccharomyces cerevisiae Ty1 retrotransposon. Genome Res (2012) 1.01
Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences. BMC Bioinformatics (2010) 0.96
A eukaryotic gene family related to retroelement integrases. Trends Genet (2005) 0.95
The Sireviruses, a plant-specific lineage of the Ty1/copia retrotransposons, interact with a family of proteins related to dynein light chain 8. Plant Physiol (2005) 0.93
Targeted deletion and inversion of tandemly arrayed genes in Arabidopsis thaliana using zinc finger nucleases. G3 (Bethesda) (2013) 0.92
Efficient design and assembly of custom TALENs using the Golden Gate platform. Methods Mol Biol (2015) 0.89
Access to DNA establishes a secondary target site bias for the yeast retrotransposon Ty5. Proc Natl Acad Sci U S A (2011) 0.88
Fanconi anemia gene editing by the CRISPR/Cas9 system. Hum Gene Ther (2015) 0.87
Targeting integration of the Saccharomyces Ty5 retrotransposon. Methods Mol Biol (2008) 0.87
TAL effector specificity for base 0 of the DNA target is altered in a complex, effector- and assay-dependent manner by substitutions for the tryptophan in cryptic repeat -1. PLoS One (2013) 0.87
A transient assay for monitoring zinc finger nuclease activity at endogenous plant gene targets. Methods Mol Biol (2010) 0.87
Targeted mutagenesis in Arabidopsis using zinc-finger nucleases. Methods Mol Biol (2011) 0.86
Vimentin Intermediate Filaments Template Microtubule Networks to Enhance Persistence in Cell Polarity and Directed Migration. Cell Syst (2016) 0.84
ZFNGenome: a comprehensive resource for locating zinc finger nuclease target sites in model organisms. BMC Genomics (2011) 0.83
Targeted mutagenesis for functional analysis of gene duplication in legumes. Methods Mol Biol (2013) 0.83
Retrotransposon target site selection by imitation of a cellular protein. Mol Cell Biol (2007) 0.81
Ty5 gag mutations increase retrotransposition and suggest a role for hydrogen bonding in the function of the nucleocapsid zinc finger. J Virol (2002) 0.81
The soybean retroelement SIRE1 uses stop codon suppression to express its envelope-like protein. EMBO Rep (2003) 0.80
Zinc Finger Database (ZiFDB) v2.0: a comprehensive database of C₂H₂ zinc fingers and engineered zinc finger arrays. Nucleic Acids Res (2012) 0.79
Retrotransposon vectors for gene delivery in plants. Mob DNA (2010) 0.77
SplitTester: software to identify domains responsible for functional divergence in protein family. BMC Bioinformatics (2005) 0.77
Tailor-made mutations in Arabidopsis using zinc finger nucleases. Methods Mol Biol (2014) 0.76
Genomics: fighting fire with fire. Nature (2008) 0.76
Welcome to mobile DNA. Mob DNA (2010) 0.75
Reviewer acknowledgement 2013. Mob DNA (2013) 0.75
Meeting report for mobile DNA 2010. Mob DNA (2010) 0.75
A CRISPR-Cpf1 system for efficient genome editing and transcriptional repression in plants. Nat Plants (2017) 0.75