Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage.

PubWeight™: 8.31‹?› | Rank: Top 0.1%

🔗 View Article (PMID 9708741)

Published in Cell on August 07, 1998

Authors

S E Lee1, J K Moore, A Holmes, K Umezu, R D Kolodner, J E Haber

Author Affiliations

1: Rosenstiel Center, Department of Biology, Brandeis University, Waltham, Massachusetts 02454-9110, USA.

Articles citing this

(truncated to the top 100)

Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (1999) 19.25

ATR: an essential regulator of genome integrity. Nat Rev Mol Cell Biol (2008) 11.86

53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell (2010) 8.70

Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol Mol Biol Rev (2002) 8.50

Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature (2008) 8.15

Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends. Cell (2008) 7.63

DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1. Nature (2004) 6.94

DNA helicases Sgs1 and BLM promote DNA double-strand break resection. Genes Dev (2008) 5.07

Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair. PLoS Genet (2008) 4.71

Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break. Curr Biol (2004) 4.35

Regulation of homologous recombination in eukaryotes. Annu Rev Genet (2010) 4.33

Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. Genes Dev (2001) 4.28

Acetylated lysine 56 on histone H3 drives chromatin assembly after repair and signals for the completion of repair. Cell (2008) 4.14

Chromatin remodelling at a DNA double-strand break site in Saccharomyces cerevisiae. Nature (2005) 4.08

Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex. Genes Dev (1999) 4.08

Genetic steps of mammalian homologous repair with distinct mutagenic consequences. Mol Cell Biol (2004) 3.96

Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair. Proc Natl Acad Sci U S A (2005) 3.93

Replication protein A-mediated recruitment and activation of Rad17 complexes. Proc Natl Acad Sci U S A (2003) 3.88

The MRE11 complex: starting from the ends. Nat Rev Mol Cell Biol (2011) 3.83

DNA damage-dependent nuclear dynamics of the Mre11 complex. Mol Cell Biol (2001) 3.78

Yeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequences. Mol Cell Biol (2003) 3.32

DNA end resection: many nucleases make light work. DNA Repair (Amst) (2009) 3.28

The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein. Genes Dev (2000) 3.25

Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks. Mol Cell (2009) 3.12

Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase. Science (2008) 3.09

Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation. Proc Natl Acad Sci U S A (1999) 3.06

EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants. Genes Dev (2002) 3.05

Differential regulation of the cellular response to DNA double-strand breaks in G1. Mol Cell (2008) 3.02

DNA length dependence of the single-strand annealing pathway and the role of Saccharomyces cerevisiae RAD59 in double-strand break repair. Mol Cell Biol (2000) 2.95

Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination. EMBO J (1998) 2.94

Functions of human replication protein A (RPA): from DNA replication to DNA damage and stress responses. J Cell Physiol (2006) 2.83

The yeast Xrs2 complex functions in S phase checkpoint regulation. Genes Dev (2001) 2.75

Mechanisms of double-strand break repair in somatic mammalian cells. Biochem J (2009) 2.68

Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4-ligase IV during chromosomal translocation formation. Nat Struct Mol Biol (2010) 2.65

The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae. Mol Cell Biol (1999) 2.51

The Mre11 nuclease is not required for 5' to 3' resection at multiple HO-induced double-strand breaks. Mol Cell Biol (2004) 2.46

Exo1 roles for repair of DNA double-strand breaks and meiotic crossing over in Saccharomyces cerevisiae. Mol Biol Cell (2000) 2.44

ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase. Genes Dev (2002) 2.40

ATM-related Tel1 associates with double-strand breaks through an Xrs2-dependent mechanism. Genes Dev (2003) 2.38

RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex. EMBO J (2005) 2.34

Competition between the Rad50 complex and the Ku heterodimer reveals a role for Exo1 in processing double-strand breaks but not telomeres. Mol Cell Biol (2003) 2.33

Genetic requirements for RAD51- and RAD54-independent break-induced replication repair of a chromosomal double-strand break. Mol Cell Biol (2001) 2.32

Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends. Proc Natl Acad Sci U S A (2007) 2.27

Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks. Genes Dev (2006) 2.27

Distinct roles for SWR1 and INO80 chromatin remodeling complexes at chromosomal double-strand breaks. EMBO J (2007) 2.23

Break dosage, cell cycle stage and DNA replication influence DNA double strand break response. EMBO J (2008) 2.21

Saccharomyces cerevisiae Sae2- and Tel1-dependent single-strand DNA formation at DNA break promotes microhomology-mediated end joining. Genetics (2007) 2.19

The basic cleft of RPA70N binds multiple checkpoint proteins, including RAD9, to regulate ATR signaling. Mol Cell Biol (2008) 2.17

Activation of ubiquitin-dependent DNA damage bypass is mediated by replication protein a. Mol Cell (2008) 2.16

Srs2 DNA helicase is involved in checkpoint response and its regulation requires a functional Mec1-dependent pathway and Cdk1 activity. EMBO J (2000) 2.15

Mechanisms that regulate localization of a DNA double-strand break to the nuclear periphery. Genes Dev (2009) 2.13

Collaboration and competition between DNA double-strand break repair pathways. FEBS Lett (2010) 2.11

Rif1 and rif2 inhibit localization of tel1 to DNA ends. Mol Cell (2009) 2.09

Targeting ATR and Chk1 kinases for cancer treatment: a new model for new (and old) drugs. Mol Oncol (2011) 2.07

Role of Saccharomyces single-stranded DNA-binding protein RPA in the strand invasion step of double-strand break repair. PLoS Biol (2004) 2.06

Interplay between Ino80 and Swr1 chromatin remodeling enzymes regulates cell cycle checkpoint adaptation in response to DNA damage. Genes Dev (2006) 2.05

Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks. EMBO J (2010) 2.04

Function of a conserved checkpoint recruitment domain in ATRIP proteins. Mol Cell Biol (2007) 2.02

A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev (2008) 2.01

Effects of mutations in DNA repair genes on formation of ribosomal DNA circles and life span in Saccharomyces cerevisiae. Mol Cell Biol (1999) 1.99

Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2002) 1.97

Repair of strand breaks by homologous recombination. Cold Spring Harb Perspect Biol (2013) 1.96

RAD51-dependent break-induced replication differs in kinetics and checkpoint responses from RAD51-mediated gene conversion. Mol Cell Biol (2005) 1.94

RSC mobilizes nucleosomes to improve accessibility of repair machinery to the damaged chromatin. Mol Cell Biol (2006) 1.94

NHEJ regulation by mating type is exercised through a novel protein, Lif2p, essential to the ligase IV pathway. Genes Dev (2001) 1.93

Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2. EMBO J (2010) 1.92

An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway. Nat Struct Mol Biol (2010) 1.92

Defective resection at DNA double-strand breaks leads to de novo telomere formation and enhances gene targeting. PLoS Genet (2010) 1.91

Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity. EMBO J (2008) 1.90

The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling. EMBO Rep (2006) 1.89

Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres. EMBO J (2008) 1.89

Rap1 prevents telomere fusions by nonhomologous end joining. EMBO J (2005) 1.87

Short telomeres induce a DNA damage response in Saccharomyces cerevisiae. Mol Biol Cell (2003) 1.86

Telomere dysfunction triggers developmentally regulated germ cell apoptosis. Mol Biol Cell (2001) 1.85

Enhancement of Saccharomyces cerevisiae end-joining efficiency by cell growth stage but not by impairment of recombination. Genetics (2002) 1.85

Requirement of the Mre11 complex and exonuclease 1 for activation of the Mec1 signaling pathway. Mol Cell Biol (2004) 1.83

Molecular dissection of mitotic recombination in the yeast Saccharomyces cerevisiae. Mol Cell Biol (2003) 1.83

RPA antagonizes microhomology-mediated repair of DNA double-strand breaks. Nat Struct Mol Biol (2014) 1.82

Telomere tethering at the nuclear periphery is essential for efficient DNA double strand break repair in subtelomeric region. J Cell Biol (2006) 1.81

Mutations in homologous recombination genes rescue top3 slow growth in Saccharomyces cerevisiae. Genetics (2002) 1.79

The karyopherin Kap142p/Msn5p mediates nuclear import and nuclear export of different cargo proteins. J Cell Biol (2001) 1.78

ATP-dependent chromatin remodeling factors and DNA damage repair. Mutat Res (2007) 1.78

Replicon dynamics, dormant origin firing, and terminal fork integrity after double-strand break formation. Cell (2009) 1.78

In vivo assembly and disassembly of Rad51 and Rad52 complexes during double-strand break repair. EMBO J (2004) 1.77

The yeast chromatin remodeler RSC complex facilitates end joining repair of DNA double-strand breaks. Mol Cell Biol (2005) 1.76

The catalytic subunit of DNA-dependent protein kinase regulates proliferation, telomere length, and genomic stability in human somatic cells. Mol Cell Biol (2008) 1.76

DNA damage response at functional and dysfunctional telomeres. Genes Dev (2008) 1.75

Maintenance of the DNA-damage checkpoint requires DNA-damage-induced mediator protein oligomerization. Mol Cell (2009) 1.73

The telomerase-recruitment domain of the telomere binding protein Cdc13 is regulated by Mec1p/Tel1p-dependent phosphorylation. Nucleic Acids Res (2006) 1.71

Human replication protein A: global fold of the N-terminal RPA-70 domain reveals a basic cleft and flexible C-terminal linker. J Biomol NMR (1999) 1.66

Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks. PLoS Genet (2011) 1.66

Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint. EMBO J (2004) 1.65

Interaction and colocalization of Rad9/Rad1/Hus1 checkpoint complex with replication protein A in human cells. Oncogene (2005) 1.59

The short life span of Saccharomyces cerevisiae sgs1 and srs2 mutants is a composite of normal aging processes and mitotic arrest due to defective recombination. Genetics (2001) 1.59

Rfc4 interacts with Rpa1 and is required for both DNA replication and DNA damage checkpoints in Saccharomyces cerevisiae. Mol Cell Biol (2001) 1.58

The role of DNA double-strand breaks in spontaneous homologous recombination in S. cerevisiae. PLoS Genet (2006) 1.57

Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response. EMBO J (2008) 1.56

ATRIP associates with replication protein A-coated ssDNA through multiple interactions. Proc Natl Acad Sci U S A (2006) 1.55

Response of Xenopus Cds1 in cell-free extracts to DNA templates with double-stranded ends. Mol Biol Cell (2000) 1.55

Chromosome healing in mouse embryonic stem cells. Proc Natl Acad Sci U S A (1999) 1.55

Articles by these authors

Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (1999) 19.25

Complete genome sequence of Salmonella enterica serovar Typhimurium LT2. Nature (2001) 16.89

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc Natl Acad Sci U S A (1998) 9.66

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet (2001) 9.34

Event-related fMRI: characterizing differential responses. Neuroimage (1998) 8.30

Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae. Mol Cell Biol (1996) 7.33

Lethal disruption of the yeast actin gene by integrative DNA transformation. Science (1982) 6.88

Intermediates of recombination during mating type switching in Saccharomyces cerevisiae. EMBO J (1990) 5.94

Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A. Nature (1993) 5.81

Characterization of double-strand break-induced recombination: homology requirements and single-stranded DNA formation. Mol Cell Biol (1992) 5.71

A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair. Cell (1997) 5.49

Removal of nonhomologous DNA ends in double-strand break recombination: the role of the yeast ultraviolet repair gene RAD1. Science (1992) 5.08

Two alternative pathways of double-strand break repair that are kinetically separable and independently modulated. Mol Cell Biol (1992) 4.97

Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae. Cell (2001) 4.96

Meiotic gene conversion and crossing over between dispersed homologous sequences occurs frequently in Saccharomyces cerevisiae. Genetics (1987) 4.94

Detecting activations in PET and fMRI: levels of inference and power. Neuroimage (1996) 4.86

Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced DNA replication. Proc Natl Acad Sci U S A (1996) 4.49

Homothallic mating type switching generates lethal chromosome breaks in rad52 strains of Saccharomyces cerevisiae. Mol Cell Biol (1981) 4.41

Genetic requirements for the single-strand annealing pathway of double-strand break repair in Saccharomyces cerevisiae. Genetics (1996) 4.33

Randomised, controlled trial of efficacy of midwife-managed care. Lancet (1996) 4.21

Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants. Nat Genet (1999) 4.18

Efficient repair of HO-induced chromosomal breaks in Saccharomyces cerevisiae by recombination between flanking homologous sequences. Mol Cell Biol (1988) 4.02

Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions. Genetics (1992) 3.97

Meiotic recombination in yeast: alteration by multiple heterozygosities. Science (1987) 3.93

A functional neuroanatomy of hallucinations in schizophrenia. Nature (1995) 3.78

Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae. Nature (2001) 3.77

Regulation of Saccharomyces Rad53 checkpoint kinase during adaptation from DNA damage-induced G2/M arrest. Mol Cell (2001) 3.74

Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2. Proc Natl Acad Sci U S A (1997) 3.66

Identification and purification of a single-stranded-DNA-specific exonuclease encoded by the recJ gene of Escherichia coli. Proc Natl Acad Sci U S A (1989) 3.65

Telomere maintenance is dependent on activities required for end repair of double-strand breaks. Curr Biol (1998) 3.63

SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination. Nat Genet (2001) 3.60

RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase. Genetics (1999) 3.55

Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae. Genetics (1994) 3.52

Anderson-Fabry disease: clinical manifestations and impact of disease in a cohort of 60 obligate carrier females. J Med Genet (2001) 3.45

Two different types of double-strand breaks in Saccharomyces cerevisiae are repaired by similar RAD52-independent, nonhomologous recombination events. Mol Cell Biol (1994) 3.40

Analysis of meiosis-defective mutations in yeast by physical monitoring of recombination. Genetics (1986) 3.38

The emergence of a highly transmissible lineage of cbl+ Pseudomonas (Burkholderia) cepacia causing CF centre epidemics in North America and Britain. Nat Med (1995) 3.36

Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae. Mol Cell Biol (1994) 3.34

Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in double-strand break-induced recombination. Proc Natl Acad Sci U S A (1997) 3.29

Two pathways for removal of nonhomologous DNA ends during double-strand break repair in Saccharomyces cerevisiae. Mol Cell Biol (1997) 3.27

An evaluation of the relatedness of proteins based on comparison of amino acid sequences. J Mol Biol (1970) 3.26

Anderson-Fabry disease: clinical manifestations and impact of disease in a cohort of 98 hemizygous males. J Med Genet (2001) 3.23

Characterization of a mutation in yeast causing nonrandom chromosome loss during mitosis. Genetics (1978) 3.21

MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast. Science (1994) 3.19

Meiotic pachytene arrest in MLH1-deficient mice. Cell (1996) 3.18

DNA structure-dependent requirements for yeast RAD genes in gene conversion. Nature (1995) 3.15

Capture of retrotransposon DNA at the sites of chromosomal double-strand breaks. Nature (1996) 3.07

Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families. Nat Med (1996) 3.07

Rad52-independent mitotic gene conversion in Saccharomyces cerevisiae frequently results in chromosomal loss. Genetics (1985) 3.01

Prevalence of hearing loss among children 6 to 19 years of age: the Third National Health and Nutrition Examination Survey. JAMA (1998) 2.98

Histological validation of myocardial microstructure obtained from diffusion tensor magnetic resonance imaging. Am J Physiol (1998) 2.97

The structure and evolution of subtelomeric Y' repeats in Saccharomyces cerevisiae. Genetics (1992) 2.96

DNA length dependence of the single-strand annealing pathway and the role of Saccharomyces cerevisiae RAD59 in double-strand break repair. Mol Cell Biol (2000) 2.95

Homothallic conversions of yeast mating-type genes occur by intrachromosomal recombination. Cell (1980) 2.95

Genetic and physical analysis of double-strand break repair and recombination in Saccharomyces cerevisiae. Genetics (1989) 2.93

Site-specific recombination determined by I-SceI, a mitochondrial group I intron-encoded endonuclease expressed in the yeast nucleus. Genetics (1992) 2.92

RAD1 and RAD10, but not other excision repair genes, are required for double-strand break-induced recombination in Saccharomyces cerevisiae. Mol Cell Biol (1995) 2.90

Double-strand break repair in yeast requires both leading and lagging strand DNA polymerases. Cell (1999) 2.89

Gene conversions and crossing over during homologous and homeologous ectopic recombination in Saccharomyces cerevisiae. Genetics (1993) 2.83

High interlaboratory reproducibility of DNA sequence-based typing of bacteria in a multicenter study. J Clin Microbiol (2006) 2.80

Expansions and contractions in a tandem repeat induced by double-strand break repair. Mol Cell Biol (1998) 2.79

The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations. Proc Natl Acad Sci U S A (1998) 2.77

Biochemical interaction of the Escherichia coli RecF, RecO, and RecR proteins with RecA protein and single-stranded DNA binding protein. Proc Natl Acad Sci U S A (1993) 2.77

Exonuclease I of Saccharomyces cerevisiae functions in mitotic recombination in vivo and in vitro. Mol Cell Biol (1997) 2.73

The chromosome end in yeast: its mosaic nature and influence on recombinational dynamics. Genetics (1994) 2.70

Chromosome break-induced DNA replication leads to nonreciprocal translocations and telomere capture. Genetics (1998) 2.55

Pleiotropic plasma membrane ATPase mutations of Saccharomyces cerevisiae. Mol Cell Biol (1987) 2.54

Rearrangements of highly polymorphic regions near telomeres of Saccharomyces cerevisiae. Mol Cell Biol (1984) 2.52

Isolation and characterization of two Saccharomyces cerevisiae genes encoding homologs of the bacterial HexA and MutS mismatch repair proteins. Genetics (1992) 2.50

Chromosomal rearrangements occur in S. cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand-break repair. Mol Cell (1998) 2.49

MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice. Genes Dev (2000) 2.49

Neural correlates of levels of emotional awareness. Evidence of an interaction between emotion and attention in the anterior cingulate cortex. J Cogn Neurosci (1998) 2.49

The genetic dependence of recombination in recD mutants of Escherichia coli. Genetics (1988) 2.49

New telomeres in yeast are initiated with a highly selected subset of TG1-3 repeats. Genes Dev (1993) 2.48

NEJ1 controls non-homologous end joining in Saccharomyces cerevisiae. Nature (2001) 2.42

Position effects in ectopic and allelic mitotic recombination in Saccharomyces cerevisiae. Genetics (1989) 2.41

Length and distribution of meiotic gene conversion tracts and crossovers in Saccharomyces cerevisiae. Genetics (1989) 2.38

The role of heteroduplex correction in gene conversion in Saccharomyces cerevisiae. Nature (1987) 2.38

Meiotic and mitotic behavior of dicentric chromosomes in Saccharomyces cerevisiae. Genetics (1984) 2.37

Identification of mismatch repair genes and their role in the development of cancer. Curr Opin Genet Dev (1995) 2.37

Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolism. Genetics (1998) 2.37

Characterization of hereditary nonpolyposis colorectal cancer families from a population-based series of cases. J Natl Cancer Inst (2000) 2.37

Healing of broken linear dicentric chromosomes in yeast. Genetics (1984) 2.35

Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines. Cancer Res (1995) 2.35

Physical monitoring of mating type switching in Saccharomyces cerevisiae. Mol Cell Biol (1988) 2.33

Specificity of mismatch repair following transformation of Saccharomyces cerevisiae with heteroduplex plasmid DNA. Proc Natl Acad Sci U S A (1989) 2.33

Impaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice. J Neurosci (2007) 2.33

Genetic requirements for RAD51- and RAD54-independent break-induced replication repair of a chromosomal double-strand break. Mol Cell Biol (2001) 2.32

Break-induced replication: a review and an example in budding yeast. Proc Natl Acad Sci U S A (2001) 2.31

Evidence of Chromosomal Breaks near the Mating-Type Locus of SACCHAROMYCES CEREVISIAE That Accompany MATalpha xMATalpha Matings. Genetics (1981) 2.28

An essential Saccharomyces cerevisiae single-stranded DNA binding protein is homologous to the large subunit of human RP-A. EMBO J (1990) 2.28

Detection of heteroduplex DNA molecules among the products of Saccharomyces cerevisiae meiosis. Proc Natl Acad Sci U S A (1990) 2.26

Strand exchange protein 1 from Saccharomyces cerevisiae. A novel multifunctional protein that contains DNA strand exchange and exonuclease activities. J Biol Chem (1991) 2.26

Protein interactions in genetic recombination in Escherichia coli. Interactions involving RecO and RecR overcome the inhibition of RecA by single-stranded DNA-binding protein. J Biol Chem (1994) 2.26

Interventions to improve antibiotic prescribing practices for hospital inpatients. Cochrane Database Syst Rev (2005) 2.25