Published in Chem Biol Interact on July 25, 2003
N-acetyltransferase (Nat) 1 and 2 expression in Nat2 knockout mice. J Pharmacol Exp Ther (2006) 0.97
N-acetyltransferase 2 activity and folate levels. Life Sci (2009) 0.76
Safe handling of nanotechnology. Nature (2006) 7.25
De novo pathogenic SCN8A mutation identified by whole-genome sequencing of a family quartet affected by infantile epileptic encephalopathy and SUDEP. Am J Hum Genet (2012) 3.58
The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice. Mol Cell Biol (2003) 2.52
Vascular targeted nanoparticles for imaging and treatment of brain tumors. Clin Cancer Res (2006) 2.46
Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Toxicol Appl Pharmacol (2007) 2.37
Speech delay and autism spectrum behaviors are frequently associated with duplication of the 7q11.23 Williams-Beuren syndrome region. Genet Med (2007) 1.98
Homozygous HOXA1 mutations disrupt human brainstem, inner ear, cardiovascular and cognitive development. Nat Genet (2005) 1.98
Real-time measurements of dissolved oxygen inside live cells by organically modified silicate fluorescent nanosensors. Anal Chem (2004) 1.97
Association between osteosarcoma and deleterious mutations in the RECQL4 gene in Rothmund-Thomson syndrome. J Natl Cancer Inst (2003) 1.83
Exome sequencing reveals new causal mutations in children with epileptic encephalopathies. Epilepsia (2013) 1.78
The new toxicology of sophisticated materials: nanotoxicology and beyond. Toxicol Sci (2010) 1.71
Brain cancer diagnosis and therapy with nanoplatforms. Adv Drug Deliv Rev (2006) 1.66
Radon, smoking, and lung cancer: the need to refocus radon control policy. Am J Public Health (2013) 1.65
Photodynamic characterization and in vitro application of methylene blue-containing nanoparticle platforms. Photochem Photobiol (2005) 1.56
FOXC2 haploinsufficient mice are a model for human autosomal dominant lymphedema-distichiasis syndrome. Hum Mol Genet (2003) 1.55
Chy-3 mice are Vegfc haploinsufficient and exhibit defective dermal superficial to deep lymphatic transition and dermal lymphatic hypoplasia. Dev Dyn (2007) 1.53
"Nanosized voltmeter" enables cellular-wide electric field mapping. Biophys J (2007) 1.37
Nanoparticles for two-photon photodynamic therapy in living cells. Nano Lett (2006) 1.37
Astrocyte-only Npc1 reduces neuronal cholesterol and triples life span of Npc1-/- mice. J Neurosci Res (2008) 1.26
Multicolored stain-free histopathology with coherent Raman imaging. Lab Invest (2012) 1.22
Review of 2,4-dichlorophenoxyacetic acid (2,4-D) epidemiology and toxicology. Crit Rev Toxicol (2002) 1.19
The clinical spectrum of homozygous HOXA1 mutations. Am J Med Genet A (2008) 1.16
Age-dependent susceptibility to manganese-induced neurological dysfunction. Toxicol Sci (2009) 1.16
Experimental non-alcoholic fatty liver disease results in decreased hepatic uptake transporter expression and function in rats. Eur J Pharmacol (2009) 1.16
In utero and postnatal exposure to arsenic alters pulmonary structure and function. Toxicol Appl Pharmacol (2008) 1.13
Allopregnanolone treatment, both as a single injection or repetitively, delays demyelination and enhances survival of Niemann-Pick C mice. J Neurosci Res (2005) 1.12
Incorporating new technologies into toxicity testing and risk assessment: moving from 21st century vision to a data-driven framework. Toxicol Sci (2013) 1.10
A novel mouse model of Niemann-Pick type C disease carrying a D1005G-Npc1 mutation comparable to commonly observed human mutations. Hum Mol Genet (2011) 1.10
Absence of RECQL4 mutations in poikiloderma with neutropenia in Navajo and non-Navajo patients. Am J Med Genet A (2003) 1.10
Encapsulation of methylene blue in polyacrylamide nanoparticle platforms protects its photodynamic effectiveness. Biochem Biophys Res Commun (2008) 1.07
DNA constructs designed to produce short hairpin, interfering RNAs in transgenic mice sometimes show early lethality and an interferon response. J Appl Genet (2005) 1.07
The role of docosahexaenoic acid in mediating mitochondrial membrane lipid oxidation and apoptosis in colonocytes. Carcinogenesis (2005) 1.07
Manganese-induced neurotoxicity: the role of astroglial-derived nitric oxide in striatal interneuron degeneration. Toxicol Sci (2006) 1.05
Athabascan brainstem dysgenesis syndrome. Am J Med Genet A (2003) 1.05
Decreased Npc1 gene dosage in mice is associated with weight gain. Obesity (Silver Spring) (2009) 1.04
Ratiometric optical PEBBLE nanosensors for real-time magnesium ion concentrations inside viable cells. Anal Chem (2003) 1.03
Rescue of neurodegeneration in Niemann-Pick C mice by a prion-promoter-driven Npc1 cDNA transgene. Hum Mol Genet (2002) 1.03
Tissue distribution and pharmacokinetics of stable polyacrylamide nanoparticles following intravenous injection in the rat. Toxicol Appl Pharmacol (2010) 1.02
1,3-Dinitrobenzene inhibits mitochondrial complex II in rat and mouse brainstem and cortical astrocytes. Neurotoxicology (2003) 1.02
Foxc2 is expressed in developing lymphatic vessels and other tissues associated with lymphedema-distichiasis syndrome. Gene Expr Patterns (2004) 1.02
Understanding Niemann-Pick type C disease: a fat problem. Curr Opin Neurol (2003) 1.01
Optochemical nanosensor PEBBLEs: photonic explorers for bioanalysis with biologically localized embedding. Curr Opin Chem Biol (2004) 1.01
In vitro characterization of a targeted, dye-loaded nanodevice for intraoperative tumor delineation. Neurosurgery (2009) 1.00
Methylene blue-conjugated hydrogel nanoparticles and tumor-cell targeted photodynamic therapy. Macromol Biosci (2011) 1.00
Diindolylmethane analogs bind NR4A1 and are NR4A1 antagonists in colon cancer cells. Mol Endocrinol (2014) 0.99
Photonic explorers based on multifunctional nanoplatforms for biosensing and photodynamic therapy. Appl Opt (2007) 0.98
Hydrogel nanoparticles with covalently linked coomassie blue for brain tumor delineation visible to the surgeon. Small (2012) 0.97
Pulmonary function and pathology in hydroxypropyl-beta-cyclodextin-treated and untreated Npc1⁻/⁻ mice. Mol Genet Metab (2011) 0.96
Toxicological and pathophysiological roles of reactive oxygen and nitrogen species. Toxicology (2010) 0.96
Manganese potentiates lipopolysaccharide-induced expression of NOS2 in C6 glioma cells through mitochondrial-dependent activation of nuclear factor kappaB. Brain Res Mol Brain Res (2004) 0.95
Hepatic gene expression and lipid homeostasis in C57BL/6 mice exposed to hydrazine or acetylhydrazine. Toxicol Sci (2004) 0.95
The brain tumor window model: a combined cranial window and implanted glioma model for evaluating intraoperative contrast agents. Neurosurgery (2010) 0.95
Suppression of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced nitric-oxide synthase 2 expression in astrocytes by a novel diindolylmethane analog protects striatal neurons against apoptosis. Mol Pharmacol (2008) 0.92
MRI detects therapeutic effects in weanling Niemann-Pick type C mice. J Neurosci Res (2008) 0.92
Nanoscale probes encapsulated by biologically localized embedding (PEBBLEs) for ion sensing and imaging in live cells. Talanta (2004) 0.92
Bioeliminable nanohydrogels for drug delivery. Nano Lett (2008) 0.91
Genetics of sexual development: a new paradigm. Am J Med Genet A (2007) 0.90
Nuclear factor kappa-B mediates selective induction of neuronal nitric oxide synthase in astrocytes during low-level inflammatory stimulation with MPTP. Brain Res (2008) 0.90
Neuropeptides modulate rat chorda tympani responses. Am J Physiol Regul Integr Comp Physiol (2003) 0.90
Amelioration of enteric neuropathology in a mouse model of Niemann-Pick C by Npc1 expression in enteric glia. J Neurosci Res (2009) 0.90
Liquid polymer nano-PEBBLEs for Cl- analysis and biological applications. Analyst (2003) 0.90
Developmental exposure to manganese increases adult susceptibility to inflammatory activation of glia and neuronal protein nitration. Toxicol Sci (2009) 0.90
Manganese potentiates nuclear factor-kappaB-dependent expression of nitric oxide synthase 2 in astrocytes by activating soluble guanylate cyclase and extracellular responsive kinase signaling pathways. J Neurosci Res (2008) 0.90
Nanoencapsulation method for high selectivity sensing of hydrogen peroxide inside live cells. Anal Chem (2010) 0.89
New technologies for nutrition research. J Nutr (2004) 0.89
Mosaic tetrasomy 12p with triplication of 12p detected by array-based comparative genomic hybridization of peripheral blood DNA. Am J Med Genet A (2007) 0.89
Modulation of intercellular calcium signaling by melatonin in avian and mammalian astrocytes is brain region-specific. J Comp Neurol (2005) 0.89
A 122.5-kilobase deletion of the P gene underlies the high prevalence of oculocutaneous albinism type 2 in the Navajo population. Am J Hum Genet (2002) 0.87
Identification of a novel C16orf57 mutation in Athabaskan patients with Poikiloderma with Neutropenia. Am J Med Genet A (2010) 0.87
Polymorphisms of the HTR1a allele are linked to frontal brain electrical asymmetry. Biol Psychol (2009) 0.86
Mice deleted for heart-type cytochrome c oxidase subunit 7a1 develop dilated cardiomyopathy. Mitochondrion (2011) 0.86
Diffusion tensor imaging in Niemann-Pick Type C disease. Pediatr Neurol (2005) 0.86
Ultrafine hydrogel nanoparticles: synthetic approach and therapeutic application in living cells. Angew Chem Int Ed Engl (2007) 0.86
Role of oxidative stress and the mitochondrial permeability transition in methylmercury cytotoxicity. Neurotoxicology (2011) 0.86
Deficiency of the cytoskeletal protein SPECC1L leads to oblique facial clefting. Am J Hum Genet (2011) 0.86
Niemann-Pick C1 mice, a model of "juvenile Alzheimer's disease", with normal gene expression in neurons and fibrillary astrocytes show long term survival and delayed neurodegeneration. J Alzheimers Dis (2012) 0.86
Neonatal ontogeny of murine arylamine N-acetyltransferases: implications for arylamine genotoxicity. Toxicol Sci (2003) 0.85
NF-kappaB-dependent production of nitric oxide by astrocytes mediates apoptosis in differentiated PC12 neurons following exposure to manganese and cytokines. Brain Res Mol Brain Res (2005) 0.85
Low-dose 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine causes inflammatory activation of astrocytes in nuclear factor-κB reporter mice prior to loss of dopaminergic neurons. J Neurosci Res (2011) 0.84
Prenatal expression of N-acetyltransferases in C57Bl/6 mice. Chem Biol Interact (2003) 0.84
Tamoxifen and vitamin E treatments delay symptoms in the mouse model of Niemann-Pick C. J Appl Genet (2004) 0.83
Gene deletion of nos2 protects against manganese-induced neurological dysfunction in juvenile mice. Toxicol Sci (2011) 0.82
One-dimensional patterning of cells in silicone wells via compression-induced fracture. J Biomed Mater Res A (2013) 0.82
Neuroprotective efficacy and pharmacokinetic behavior of novel anti-inflammatory para-phenyl substituted diindolylmethanes in a mouse model of Parkinson's disease. J Pharmacol Exp Ther (2013) 0.82
Proteomic identification of carbonylated proteins in 1,3-dinitrobenzene neurotoxicity. Neurotoxicology (2011) 0.82
CI-1010 induced opening of the mitochondrial permeability transition pore precedes oxidative stress and apoptosis in SY5Y neuroblastoma cells. Brain Res (2003) 0.81
Manganese-induced NF-kappaB activation and nitrosative stress is decreased by estrogen in juvenile mice. Toxicol Sci (2011) 0.81
The role of decreased levels of Niemann-Pick C1 intracellular cholesterol transport on obesity is reversed in the C57BL/6J, metabolic syndrome mouse strain: a metabolic or an inflammatory effect? J Appl Genet (2012) 0.81
In vivo assessment of neurodegeneration in Niemann-Pick type C mice by quantitative T2 mapping and diffusion tensor imaging. J Magn Reson Imaging (2011) 0.81
Modulation of hydrogel nanoparticle intracellular trafficking by multivalent surface engineering with tumor targeting peptide. Nanoscale (2013) 0.81
Analysis of targeted mutation in DJ-1 on cellular function in primary astrocytes. Toxicol Lett (2008) 0.80
Manganese inhibits ATP-induced calcium entry through the transient receptor potential channel TRPC3 in astrocytes. Neurotoxicology (2012) 0.80
1,3-Dinitrobenzene-induced metabolic impairment through selective inactivation of the pyruvate dehydrogenase complex. Toxicol Sci (2011) 0.80
Thalidomide modulates nuclear redox status and preferentially depletes glutathione in rabbit limb versus rat limb. J Pharmacol Exp Ther (2002) 0.80