Published in Proc Natl Acad Sci U S A on August 05, 2003
Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy. Nat Methods (2008) 6.75
All tangled up: how cells direct, manage and exploit topoisomerase function. Nat Rev Mol Cell Biol (2011) 2.66
The C-terminal domain of DNA gyrase A adopts a DNA-bending beta-pinwheel fold. Proc Natl Acad Sci U S A (2004) 1.93
A topological view of the replicon. EMBO Rep (2004) 1.76
Single-molecule analysis reveals the molecular bearing mechanism of DNA strand exchange by a serine recombinase. Proc Natl Acad Sci U S A (2011) 1.52
Mechanisms of chiral discrimination by topoisomerase IV. Proc Natl Acad Sci U S A (2009) 1.38
Topoisomerase II, not topoisomerase I, is the proficient relaxase of nucleosomal DNA. EMBO J (2006) 1.38
Braiding DNA: experiments, simulations, and models. Biophys J (2005) 1.16
Mechanics of DNA bridging by bacterial condensin MukBEF in vitro and in singulo. EMBO J (2010) 1.04
Remote control of DNA-acting enzymes by varying the Brownian dynamics of a distant DNA end. Proc Natl Acad Sci U S A (2012) 1.04
DNA supercoiling and its role in DNA decatenation and unknotting. Nucleic Acids Res (2009) 1.01
Twisting and untwisting a single DNA molecule covered by RecA protein. Biophys J (2004) 1.00
Simulations of action of DNA topoisomerases to investigate boundaries and shapes of spaces of knots. Biophys J (2004) 0.97
Interplay of DNA supercoiling and catenation during the segregation of sister duplexes. Nucleic Acids Res (2009) 0.97
Mechanisms for defining supercoiling set point of DNA gyrase orthologs: I. A nonconserved acidic C-terminal tail modulates Escherichia coli gyrase activity. J Biol Chem (2012) 0.97
Rotation of DNA around intact strand in human topoisomerase I implies distinct mechanisms for positive and negative supercoil relaxation. Nucleic Acids Res (2005) 0.93
The SMC1-SMC3 cohesin heterodimer structures DNA through supercoiling-dependent loop formation. Nucleic Acids Res (2013) 0.92
Single-molecule measurements of DNA topology and topoisomerases. J Biol Chem (2010) 0.92
Helical chirality: a link between local interactions and global topology in DNA. PLoS One (2010) 0.90
DNA chirality-dependent stimulation of topoisomerase IV activity by the C-terminal AAA+ domain of FtsK. Nucleic Acids Res (2010) 0.89
Differential stability of DNA crossovers in solution mediated by divalent cations. Nucleic Acids Res (2010) 0.89
Local sensing of global DNA topology: from crossover geometry to type II topoisomerase processivity. Nucleic Acids Res (2011) 0.87
Structural basis for the MukB-topoisomerase IV interaction and its functional implications in vivo. EMBO J (2013) 0.87
Motor proteins and molecular motors: how to operate machines at the nanoscale. J Phys Condens Matter (2013) 0.87
The bacterial nucleoid: nature, dynamics and sister segregation. Curr Opin Microbiol (2014) 0.86
Topoisomerase IV bends and overtwists DNA upon binding. Biophys J (2005) 0.86
Ability of viral topoisomerase II to discern the handedness of supercoiled DNA: bimodal recognition of DNA geometry by type II enzymes. Biochemistry (2006) 0.86
Electrostatic braiding and homologous pairing of DNA double helices. Biophys J (2011) 0.83
Chiral discrimination and writhe-dependent relaxation mechanism of human topoisomerase IIα. J Biol Chem (2013) 0.83
Comparison of DNA decatenation by Escherichia coli topoisomerase IV and topoisomerase III: implications for non-equilibrium topology simplification. Nucleic Acids Res (2013) 0.83
Distinct regions of the Escherichia coli ParC C-terminal domain are required for substrate discrimination by topoisomerase IV. J Mol Biol (2013) 0.83
Simulation of DNA catenanes. Phys Chem Chem Phys (2009) 0.83
Mapping Topoisomerase IV Binding and Activity Sites on the E. coli Genome. PLoS Genet (2016) 0.83
The Dynamic Interplay Between DNA Topoisomerases and DNA Topology. Biophys Rev (2016) 0.81
Chromatin regulates DNA torsional energy via topoisomerase II-mediated relaxation of positive supercoils. EMBO J (2014) 0.81
Direct observation of strand passage by DNA-topoisomerase and its limited processivity. PLoS One (2012) 0.80
DNA topoisomerase IIα controls replication origin cluster licensing and firing time in Xenopus egg extracts. Nucleic Acids Res (2013) 0.80
Chromosome length and perinuclear attachment constrain resolution of DNA intertwines. J Cell Biol (2014) 0.80
ATP-independent cooperative binding of yeast Isw1a to bare and nucleosomal DNA. PLoS One (2012) 0.79
Genome maintenance in the context of 4D chromatin condensation. Cell Mol Life Sci (2016) 0.77
Single-molecule analysis uncovers the difference between the kinetics of DNA decatenation by bacterial topoisomerases I and III. Nucleic Acids Res (2014) 0.77
DNA self-assembly: from chirality to evolution. Int J Mol Sci (2013) 0.77
A cell cycle-controlled redox switch regulates the topoisomerase IV activity. Genes Dev (2015) 0.76
Direct Evidence for the Formation of Precatenanes during DNA Replication. J Biol Chem (2015) 0.76
On the topology of chromatin fibres. Interface Focus (2012) 0.76
The tail that wags the dog: topoisomerase IV ParC C-terminal domain controls strand passage activity through multipartite topology-dependent interactions with DNA. J Mol Biol (2013) 0.75
The dynamic interplay between DNA topoisomerases and DNA topology. Biophys Rev (2016) 0.75
Controlled rotation mechanism of DNA strand exchange by the Hin serine recombinase. Sci Rep (2016) 0.75
Evolutionary twist on topoisomerases: conversion of gyrase to topoisomerase IV. Proc Natl Acad Sci U S A (2010) 0.75
Entropic elasticity of lambda-phage DNA. Science (1994) 15.40
Cellular roles of DNA topoisomerases: a molecular perspective. Nat Rev Mol Cell Biol (2002) 11.79
Direct mechanical measurements of the elasticity of single DNA molecules by using magnetic beads. Science (1992) 9.74
The elasticity of a single supercoiled DNA molecule. Science (1996) 8.58
Force and velocity measured for single molecules of RNA polymerase. Science (1998) 7.15
Behavior of supercoiled DNA. Biophys J (1998) 4.86
The role of topoisomerase IV in partitioning bacterial replicons and the structure of catenated intermediates in DNA replication. Cell (1992) 3.88
Type II DNA topoisomerases: enzymes that can unknot a topologically knotted DNA molecule via a reversible double-strand break. Cell (1980) 3.83
Isolation and characterisation of a strain carrying a conditional lethal mutation in the cou gene of Escherichia coli K12. Mol Gen Genet (1979) 3.74
Simplification of DNA topology below equilibrium values by type II topoisomerases. Science (1997) 3.05
Roles of topoisomerase IV and DNA gyrase in DNA unlinking during replication in Escherichia coli. Genes Dev (1995) 3.01
DNA gyrase and topoisomerase IV: biochemical activities, physiological roles during chromosome replication, and drug sensitivities. Biochim Biophys Acta (1998) 3.00
Probability of DNA knotting and the effective diameter of the DNA double helix. Proc Natl Acad Sci U S A (1993) 2.79
Single-molecule analysis of DNA uncoiling by a type II topoisomerase. Nature (2000) 2.78
Moving one DNA double helix through another by a type II DNA topoisomerase: the story of a simple molecular machine. Q Rev Biophys (1998) 2.62
Bacterial chromosome segregation: evidence for DNA gyrase involvement in decatenation. Cell (1984) 2.58
Structure of plectonemically supercoiled DNA. J Mol Biol (1990) 2.48
The capture of a DNA double helix by an ATP-dependent protein clamp: a key step in DNA transport by type II DNA topoisomerases. Cell (1992) 2.48
Topological challenges to DNA replication: conformations at the fork. Proc Natl Acad Sci U S A (2001) 2.11
Effect of supercoiling on the juxtaposition and relative orientation of DNA sites. Biophys J (1996) 1.97
Preferential relaxation of positively supercoiled DNA by E. coli topoisomerase IV in single-molecule and ensemble measurements. Genes Dev (2000) 1.94
The structure of supercoiled intermediates in DNA replication. Cell (1998) 1.75
Contrasting enzymatic activities of topoisomerase IV and DNA gyrase from Escherichia coli. J Biol Chem (1996) 1.64
Homologous pairing in stretched supercoiled DNA. Proc Natl Acad Sci U S A (1998) 1.63
Two distinct modes of strand unlinking during theta-type DNA replication. J Biol Chem (1996) 1.38
A locus affecting nucleoid segregation in Salmonella typhimurium. J Bacteriol (1990) 1.33
Topoisomerase III can serve as the cellular decatenase in Escherichia coli. J Biol Chem (2002) 1.23
The probabilities of supercoil removal and decatenation by yeast DNA topoisomerase II. Genes Cells (1996) 1.16
The elasticity of a single supercoiled DNA molecule. Science (1996) 8.58
Behavior of supercoiled DNA. Biophys J (1998) 4.86
Estimating the persistence length of a worm-like chain molecule from force-extension measurements. Biophys J (1999) 4.42
Alignment and sensitive detection of DNA by a moving interface. Science (1994) 4.18
Replication by a single DNA polymerase of a stretched single-stranded DNA. Proc Natl Acad Sci U S A (2000) 3.29
Single-molecule analysis of DNA uncoiling by a type II topoisomerase. Nature (2000) 2.78
Stretched and overwound DNA forms a Pauling-like structure with exposed bases. Proc Natl Acad Sci U S A (1998) 2.35
Twisting and stretching single DNA molecules. Prog Biophys Mol Biol (2000) 2.18
Preferential relaxation of positively supercoiled DNA by E. coli topoisomerase IV in single-molecule and ensemble measurements. Genes Dev (2000) 1.94
Stretching single stranded DNA, a model polyelectrolyte. Phys Rev Lett (2002) 1.90
Homologous pairing in stretched supercoiled DNA. Proc Natl Acad Sci U S A (1998) 1.63
pH-dependent specific binding and combing of DNA. Biophys J (1997) 1.60
Tracking topoisomerase activity at the single-molecule level. Annu Rev Biophys Biomol Struct (2005) 1.44
The mechanism of type IA topoisomerases. Proc Natl Acad Sci U S A (2002) 1.43
Mechanisms of chiral discrimination by topoisomerase IV. Proc Natl Acad Sci U S A (2009) 1.38
Micro-mechanical measurement of the torsional modulus of DNA. Genetica (1999) 1.22
Braiding DNA: experiments, simulations, and models. Biophys J (2005) 1.16
Stress-induced structural transitions in DNA and proteins. Annu Rev Biophys Biomol Struct (2000) 1.10
Single-molecule study of RuvAB-mediated Holliday-junction migration. Proc Natl Acad Sci U S A (2004) 1.10
Single-molecule DNA nanomanipulation: detection of promoter-unwinding events by RNA polymerase. Methods Enzymol (2003) 1.08
Observation of stable shapes and conformal diffusion in genus 2 vesicles. Science (1995) 1.02
Thermophilic topoisomerase I on a single DNA molecule. J Mol Biol (2003) 0.98
Statistical determination of the step size of molecular motors. J Phys Condens Matter (2005) 0.95
Topoisomerase IV bends and overtwists DNA upon binding. Biophys J (2005) 0.86
Temperature modulation and quadrature detection for selective titration of two-state exchanging reactants. Anal Chem (2011) 0.83
Gene regulation under growth conditions. A model for the regulation of initiation of replication in Escherichia coli. J Theor Biol (1991) 0.79
Validation of a clinical evaluation score for irritative dermatitis: SCOREPI. J Eur Acad Dermatol Venereol (2012) 0.75
Statistical properties of He-Ne laser radiation reflected through a turbulent atmosphere. Appl Opt (1981) 0.75
Fourier analysis to measure diffusion coefficients and resolve mixtures on a continuous electrophoresis chip. Anal Chem (2007) 0.75
[Anatomical study of the treatment of interradicular lesions of the molar]. J Parodontol (1987) 0.75