Published in Gene on July 17, 2003
The antiproliferative action of progesterone in uterine epithelium is mediated by Hand2. Science (2011) 2.46
Defining the transcriptional redundancy of early bodywall muscle development in C. elegans: evidence for a unified theory of animal muscle development. Genes Dev (2006) 2.33
Normal and disease-related biological functions of Twist1 and underlying molecular mechanisms. Cell Res (2011) 1.99
A developmental taxonomy of glioblastoma defined and maintained by MicroRNAs. Cancer Res (2011) 1.89
Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalities. Nat Genet (2005) 1.89
Re-employment of developmental transcription factors in adult heart disease. Semin Cell Dev Biol (2006) 1.82
Endothelin-A receptor-dependent and -independent signaling pathways in establishing mandibular identity. Development (2004) 1.67
Hand2 loss-of-function in Hand1-expressing cells reveals distinct roles in epicardial and coronary vessel development. Circ Res (2011) 1.57
Cis-regulatory variations: a study of SNPs around genes showing cis-linkage in segregating mouse populations. BMC Genomics (2006) 1.53
ApoE Receptor 2 Mediation of Trophoblast Dysfunction and Pregnancy Complications Induced by Antiphospholipid Antibodies in Mice. Arthritis Rheumatol (2016) 1.44
Mutations within helix I of Twist1 result in distinct limb defects and variation of DNA binding affinities. J Biol Chem (2007) 1.34
DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer. Cancer Res (2009) 1.26
An absence of Twist1 results in aberrant cardiac neural crest morphogenesis. Dev Biol (2008) 1.22
Downregulation of Dlx5 and Dlx6 expression by Hand2 is essential for initiation of tongue morphogenesis. Development (2011) 1.20
Using a structural and logics systems approach to infer bHLH-DNA binding specificity determinants. Nucleic Acids Res (2011) 1.15
Phosphoregulation of Twist1 provides a mechanism of cell fate control. Curr Med Chem (2008) 1.09
Hand factors as regulators of cardiac morphogenesis and implications for congenital heart defects. Birth Defects Res A Clin Mol Teratol (2011) 1.03
Targeted deletion of Hand2 in cardiac neural crest-derived cells influences cardiac gene expression and outflow tract development. Dev Biol (2010) 0.96
Caudal-like PAL-1 directly activates the bodywall muscle module regulator hlh-1 in C. elegans to initiate the embryonic muscle gene regulatory network. Development (2009) 0.95
Differential regulation of Hand1 homodimer and Hand1-E12 heterodimer activity by the cofactor FHL2. Mol Cell Biol (2004) 0.95
Analysis of the Hand1 cell lineage reveals novel contributions to cardiovascular, neural crest, extra-embryonic, and lateral mesoderm derivatives. Dev Dyn (2010) 0.94
Identification of dysfunctional modules and disease genes in congenital heart disease by a network-based approach. BMC Genomics (2011) 0.93
Fluorescence Resonance Energy Transfer (FRET) as a method to calculate the dimerization strength of basic Helix-Loop-Helix (bHLH) proteins. Biol Proced Online (2004) 0.92
A bHLH code for cardiac morphogenesis. Pediatr Cardiol (2009) 0.91
Trophoblast gene expression: transcription factors in the specification of early trophoblast. Reprod Biol Endocrinol (2004) 0.91
Identification of temporal and region-specific myocardial gene expression patterns in response to infarction in swine. PLoS One (2013) 0.91
Pbx acts with Hand2 in early myocardial differentiation. Dev Biol (2009) 0.90
DNA binding-dependent and -independent functions of the Hand2 transcription factor during mouse embryogenesis. Development (2009) 0.89
Co-regulated expression of HAND2 and DEIN by a bidirectional promoter with asymmetrical activity in neuroblastoma. BMC Mol Biol (2009) 0.89
The Drosophila Hand gene is required for remodeling of the developing adult heart and midgut during metamorphosis. Dev Biol (2007) 0.88
Phosphopeptide mapping of proteins ectopically expressed in tissue culture cell lines. Biol Proced Online (2004) 0.87
Prx1 and Prx2 cooperatively regulate the morphogenesis of the medial region of the mandibular process. Dev Dyn (2009) 0.86
Expression level of Hand2 affects specification of enteric neurons and gastrointestinal function in mice. Gastroenterology (2011) 0.85
Phosphorylation of the Twist1-family basic helix-loop-helix transcription factors is involved in pathological cardiac remodeling. PLoS One (2011) 0.82
Combinatorial transcriptional interaction within the cardiac neural crest: a pair of HANDs in heart formation. Birth Defects Res C Embryo Today (2004) 0.81
Somatic muscle specification during embryonic and post-embryonic development in the nematode C. elegans. Wiley Interdiscip Rev Dev Biol (2011) 0.80
Analysis of a Hand1 hypomorphic allele reveals a critical threshold for embryonic viability. Dev Dyn (2010) 0.80
Scleraxis is required for differentiation of the stapedius and tensor tympani tendons of the middle ear. J Assoc Res Otolaryngol (2011) 0.78
Daxx inhibits muscle differentiation by repressing E2A-mediated transcription. J Cell Biochem (2009) 0.77
Conservation and divergence of bHLH genes in the calcisponge Sycon ciliatum. Evodevo (2016) 0.77
Gene replacement strategies to test the functional redundancy of basic helix-loop-helix transcription factor. Pediatr Cardiol (2010) 0.77
A Haplotype of Two Novel Polymorphisms in δ-Sarcoglycan Gene Increases Risk of Dilated Cardiomyopathy in Mongoloid Population. PLoS One (2015) 0.76
A seriation approach for visualization-driven discovery of co-expression patterns in Serial Analysis of Gene Expression (SAGE) data. PLoS One (2008) 0.75